Lateral Wedge Insole With Subtalar Strapping for Knee Osteoarthritis
Primary Purpose
Osteoarthritis
Status
Completed
Phase
Not Applicable
Locations
Brazil
Study Type
Interventional
Intervention
Neutral insole with subtalar strapping (sham)
Lateral wedge insole with subtalar strapping
Sponsored by

About this trial
This is an interventional treatment trial for Osteoarthritis focused on measuring osteoarthritis, osteoarthritis, knee, foot orthoses, orthotic insoles
Eligibility Criteria
Inclusion Criteria:
- Meet the American College of Rheumatology criteria for knee Osteoarthritis
- Varus malalignment of the knee
- Absence of previous fracture on the index knee
- Absence of previous surgery on the index knee
- Absence of Rheumatoid Arthritis
- No Intra-articular injection on the index knee in the past 6 months
- Receiving usual care for Osteoarthritis for at least 6 months
- Be able to understand and agree with the informed consent
Exclusion Criteria:
- Undergo surgery during the study
- Undergo Intra-articular injection during the study
- Develop articular infection of the index joint during the study
Sites / Locations
- Instituto de Ortopedia e Traumatologia HC-FMUSP
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Sham Comparator
Arm Label
Wedge
Neutral
Arm Description
Lateral wedge insole with subtalar strapping Use of lateral wedge insoles with subtalar strapping for 5 to 10 hours daily
Neutral insole with subtalar strapping (sham) Use of neutral insoles with subtalar strapping for 5 to 10 hours daily
Outcomes
Primary Outcome Measures
Symptoms
Evaluation of patient's symptoms using WOMAC (western ontario and mcmaster universities osteoarthritis index), VAS (visual analogic scale of pain) and Lequesne questionaires
Secondary Outcome Measures
Ankle pain
Number of patients that reported ankle pain related to the use of the insole as a measure of tolerability
Full Information
NCT ID
NCT01739296
First Posted
November 22, 2012
Last Updated
September 10, 2013
Sponsor
University of Sao Paulo General Hospital
1. Study Identification
Unique Protocol Identification Number
NCT01739296
Brief Title
Lateral Wedge Insole With Subtalar Strapping for Knee Osteoarthritis
Official Title
Lateral Wedge Insole With Subtalar Strapping for Knee Osteoarthritis: a Randomized Clinical Trial
Study Type
Interventional
2. Study Status
Record Verification Date
September 2013
Overall Recruitment Status
Completed
Study Start Date
June 2011 (undefined)
Primary Completion Date
February 2012 (Actual)
Study Completion Date
July 2012 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University of Sao Paulo General Hospital
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
This is a clinical study to evaluate the efficacy of a lateral wedge insole with subtalar strapping in knee osteoarthritis treatment.
Detailed Description
The objective of this study is to evaluate the efficacy of a lateral wedge insole with subtalar strapping in knee osteoarthritis treatment. Fifty-eight patients with knee osteoarthritis were randomized to use either a lateral wedge or a neutral insole. VAS, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Lequesne questionnaires were applied at baseline, and weeks two, eight, and 24.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Osteoarthritis
Keywords
osteoarthritis, osteoarthritis, knee, foot orthoses, orthotic insoles
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Investigator
Allocation
Randomized
Enrollment
58 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Wedge
Arm Type
Experimental
Arm Description
Lateral wedge insole with subtalar strapping Use of lateral wedge insoles with subtalar strapping for 5 to 10 hours daily
Arm Title
Neutral
Arm Type
Sham Comparator
Arm Description
Neutral insole with subtalar strapping (sham) Use of neutral insoles with subtalar strapping for 5 to 10 hours daily
Intervention Type
Other
Intervention Name(s)
Neutral insole with subtalar strapping (sham)
Other Intervention Name(s)
Neutral
Intervention Description
Neutral insole with subtalar strapping (sham)
Intervention Type
Other
Intervention Name(s)
Lateral wedge insole with subtalar strapping
Other Intervention Name(s)
Wedge
Intervention Description
Lateral wedge insole with subtalar strapping
Primary Outcome Measure Information:
Title
Symptoms
Description
Evaluation of patient's symptoms using WOMAC (western ontario and mcmaster universities osteoarthritis index), VAS (visual analogic scale of pain) and Lequesne questionaires
Time Frame
24 weeks
Secondary Outcome Measure Information:
Title
Ankle pain
Description
Number of patients that reported ankle pain related to the use of the insole as a measure of tolerability
Time Frame
24 weeks
10. Eligibility
Sex
All
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Meet the American College of Rheumatology criteria for knee Osteoarthritis
Varus malalignment of the knee
Absence of previous fracture on the index knee
Absence of previous surgery on the index knee
Absence of Rheumatoid Arthritis
No Intra-articular injection on the index knee in the past 6 months
Receiving usual care for Osteoarthritis for at least 6 months
Be able to understand and agree with the informed consent
Exclusion Criteria:
Undergo surgery during the study
Undergo Intra-articular injection during the study
Develop articular infection of the index joint during the study
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Gustavo C Campos, MD
Organizational Affiliation
FMUSP
Official's Role
Principal Investigator
Facility Information:
Facility Name
Instituto de Ortopedia e Traumatologia HC-FMUSP
City
São Paulo
State/Province
SP
ZIP/Postal Code
05410-000
Country
Brazil
12. IPD Sharing Statement
Links:
URL
http://sbot.org.br
Description
Brazilian Orthopaedics Association
URL
http://iothcfmusp.com.br
Description
Orthopaedics and Traumatology Institute website
URL
http://fmusp.org.br
Description
University of São Paulo website
URL
http://sbcj.org.br
Description
Brazilian Knee Surgery Association website
Learn more about this trial
Lateral Wedge Insole With Subtalar Strapping for Knee Osteoarthritis
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