Use of the Medical Device DECAP CO2 for the Treatment of Hypercapnic Respiratory Distress in Patients Under Noninvasive Ventilation (DECAP CO2)
Respiratory Distress Syndrome, Hypercapnia
About this trial
This is an interventional treatment trial for Respiratory Distress Syndrome focused on measuring Hypercapnia, Respiratory Distress Syndrome, Extracorporeal CO2 remover, Noninvasive ventilation
Eligibility Criteria
Inclusion Criteria:
Adult patient suffering from severe chronic respiratory failure
- Chronic obstructive pulmonary disease : stage III
- Hypercapnic respiratory decomposition
- No anticipated directive with the treating physician, pulmonologist or his family.
- Challenged for invasive ventilation by critical care doctor, emergency doctor or pulmonologist ; due to the respiratory pathology severity or other (age, comorbidity)
- Not challenged for a noninvasive ventilation
- Failure of the noninvasive ventilation in intensive care unit (pH decrease due to hypercapnia after 2 hours of noninvasive ventilation
Obtaining of the consent of the patient or the reliable person or the close relation
Exclusion Criteria:
- - Patients who made anticipated directives (decision of the patient to have no tracheotomy, intubation, noninvasive ventilation)
- Contraindication to heparin (active bleeding, Heparin-induced thrombocytopenia)
- Patients < 18 years and > 90 years
- Patients already included in another therapeutic trial
- Pregnant woman or breast feeding
- Legal incapacity
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Other
noninvasive ventilation alone
noninvasive ventilation associated with the DECAP CO2 device
After validation of the inclusion and exclusion criteria, the patients include in this clinical trial will be randomized between the two arms of the study: Noninvasive ventilation alone Noninvasive ventilation associated with the DECAP CO2 device
After validation of the inclusion and exclusion criteria, the patients include in this clinical trial will be randomized between the two arms of the study: Noninvasive ventilation alone Noninvasive ventilation associated with the DECAP CO2 device