search
Back to results

Study Evaluating the Safety, Tolerability, and Efficacy of Dexmecamylamine (TC-5214) for Treatment of Overactive Bladder

Primary Purpose

Overactive Bladder

Status
Completed
Phase
Phase 2
Locations
United States
Study Type
Interventional
Intervention
dexmecamylamine
Placebo
Sponsored by
Targacept Inc.
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Overactive Bladder

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Verified medical history of overactive bladder for at least 6 months
  • Capable of walking unassisted to use the bathroom
  • Able to measure voided urine volume and complete the diary without assistance
  • If the subject is currently being treated with an OAB medication, the subject is willing to discontinue OAB medications while participating in this study

Exclusion Criteria:

  • Diagnosis of a neurological disease affecting bladder function
  • Stress incontinence, insensate incontinence, overflow incontinence or incontinence due to urinary fistula
  • History of incomplete bladder emptying, bladder outflow obstruction or post-void residual bladder volume > 150 mL
  • Males with benign prostatic hyperplasia or with a prostate-specific antigen (PSA) of 4 ng/mL or more
  • Other urinary tract pathology such as malignancy, ureteric reflux, bladder stone, uninvestigated hematuria, urethral stricture, or cystitis
  • Prior treatment with intravesical or intraprostatic botulinum toxin in the last 2 years
  • Myasthenia gravis
  • Angle closure glaucoma
  • Current implantation of interstim electrodes or vaginal surgical mesh
  • Presence of a clinically significant medical condition at any time during the study
  • Presence of clinically significant abnormalities in laboratory findings, physical exam findings or vital signs
  • Participated in an investigational drug trial within 3 months of screening

Sites / Locations

  • Simon-Williamson Clinic, P.C.
  • Physician's Resource Group
  • Coastal Clinical Research, Inc.
  • Coastal Clinical Research, Inc
  • Mobile Ob-Gyn, P.C.
  • Radiant Research, Inc.
  • Clinical Trials of Arizona, Inc.
  • Beach Clinical Studies
  • Radiant Research, Inc.
  • Genova Clinical Research, Inc.
  • Radiant Research, Inc.
  • Lynn Institute of the Ozarks
  • Atlantic Urology Medical Group
  • Adam D. Karnes, MD
  • Tri Valley Urology Medical Group
  • Center for Clinical Trials, LLC
  • Northern California Research
  • San Diego Sexual Medicine
  • Genesis Research
  • Westlake Medical Research
  • InFocus Clinical Research
  • Horizons Clinical Research Center, LLC
  • Women's Health Specialty Care
  • Connecticut Clinical Research Center, LLC
  • South Florida Medical Research
  • Meridien Reseach
  • Tampa Bay Medical Research
  • 3H Clinical Research Corporation
  • Palm Spring Research Institute
  • American Medical Research Institute
  • Altus Research
  • Sunrise Medical Research
  • Suncoast Clinical Research, Inc.
  • Advanced Research Institute, Inc.
  • Clinical Research of Central Florida
  • Lakeview Medical Research
  • Southeastern Research Group, Inc.
  • Palm Beach Research Center
  • Clinical Research of Central Florida
  • Atlanta Medical Research Institute
  • Radiant Reseach, Inc.
  • Southeast Regional Research Group
  • Perimeter North Medical Research, Inc.
  • Fellows Research Alliance, Inc.
  • North Georgia Clinical Research
  • North Idaho Urology
  • Radiant Research, Inc.
  • Clinical Investigation Specialists, Inc.
  • First Urology PSC
  • Deaconess Clinic Gateway Health Center
  • Heartland Research Associates, LLC
  • Heartland Research Associates, LLC
  • GTC Research
  • Heartland Research Associates, LLC
  • Bluegrass Clinical Research
  • Research Integrity, LLC
  • Regional Urology, LLC
  • Willis-Knighton Physician Network
  • Mid Atlantic Urology Associates, LLC
  • Boston Clinical Trials, Inc.
  • Beacon Clinical Research, LLC
  • Bay State Clinical Trials, Inc.
  • Family Medicine Specialists, PC
  • Beyer Research
  • Westside Family Medical Center, PC
  • William Beaumont Hospital
  • Saginaw Valley Medical Reseach Group, LLC
  • Radiant Research, Inc.
  • Metro Urology
  • Mississippi Medical Research, LLC
  • Center for Pharmaceutical Research
  • Radiant Research, Inc.
  • Montana Health Research Institute, Inc.
  • Five Valleys Urology
  • Women's Clinical of Lincoln, P.C.
  • Quality Clinical Research, Inc.
  • Summit Medical Group
  • Comprehensive Clinical Research
  • Lawrence OB-GYN Clinical Research, LLC
  • Delaware Valley Urology, LLC
  • Albuquerque Clinical Trials, Inc.
  • SouthWest Clinical Research
  • The Urological Institute of Northeastern New York
  • Advanced Urology Centers of New York
  • Premier Medical Group of the Hudson Valley, PC
  • Manhattan Medical Research Practice PLLC
  • Premier Medical Group of the Hudson Valley, PC
  • Rochester Clinical Research, Inc.
  • Wake Research Associates, LLC
  • PMG Research of Wilmington
  • Lyndhurst Clinical Research
  • Radiant Research, Inc.
  • Rapid Medical Research, Inc.
  • The Cleveland Clinic
  • Radiant Research, Inc.
  • Physicians' Research, Inc.
  • Urologic Consultants of SE PA
  • Altoona Center for Clinical Research
  • Clinical Research of Philadelphia, LLC
  • Advanced Clinical Concepts
  • Greater Providence Clinical Research, LLC
  • Radiant Research, Inc.
  • Fellows Research Alliance, Inc.
  • Medical Research South, LLC
  • Coastal Carolina Research Center
  • Carolina Urologic Research Center
  • Hillcrest Clinical Research, LLC
  • Meridian Clinical Research
  • The Jackson Clinic
  • Advanced Therapeutics, Inc.
  • Tennesse Women's Care
  • Tekton Research, Inc.
  • DiscoverResearch, Inc.
  • Research Across America
  • Research Across America
  • DCOL Center for Clinical Research
  • Quality Research Inc.
  • Clinical Trials of Texas, Inc.
  • Radiant Reseach, Inc.
  • Wasatch Clinical Research
  • The Group for Women
  • Clinical Research Associates of Tidewater, Inc.
  • Integrity Medical Research, LLC
  • Valley Women's Clinic
  • Seattle Women's Health, Research, Gynecology

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm Type

Placebo Comparator

Experimental

Experimental

Experimental

Arm Label

Placebo

0.5 mg dexmecamylamine (TC-5214)

1 mg dexmecamylamine (TC-5214)

2 mg dexmecamylamine (TC-5214)

Arm Description

One tablet of placebo to be administered orally twice a day.

One tablet of 0.5 mg dexmecamylamine to be administered orally twice a day.

One tablet of 1 mg dexmecamylamine to be administered orally twice a day.

One tablet of 2 mg dexmecamylamine to be administered orally twice a day.

Outcomes

Primary Outcome Measures

Change from baseline in micturition frequency per 24 hours
Micturition: Any voiding episode recorded by the patient as "urinated" either with or without incontinence.
Change from baseline in urinary urge incontinence (UUI) episodes per 24 hours

Secondary Outcome Measures

Change from baseline in the volume voided per micturition
Change from baseline in nocturia per 24 hours
Nocturia: A micturition that wakes the subject from sleep between the time the subject went to bed and the time the subject woke up.
Clinical Global Impression of Improvement (CGI-I)
Change from baseline in Patient Perception of Bladder Condition (PPBC)
Change from baseline in the Urgency Questionnaire
Change from baseline in disease specific quality of life (OABq)

Full Information

First Posted
May 30, 2013
Last Updated
May 11, 2015
Sponsor
Targacept Inc.
search

1. Study Identification

Unique Protocol Identification Number
NCT01868516
Brief Title
Study Evaluating the Safety, Tolerability, and Efficacy of Dexmecamylamine (TC-5214) for Treatment of Overactive Bladder
Study Type
Interventional

2. Study Status

Record Verification Date
August 2014
Overall Recruitment Status
Completed
Study Start Date
May 2013 (undefined)
Primary Completion Date
June 2014 (Actual)
Study Completion Date
June 2014 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Targacept Inc.

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
Overactive bladder (OAB) is a syndrome characterized by symptoms of a sudden need to urinate with or without incontinence (leaking). The purpose of this study is to test whether dexmecamylamine is safe and effective compared to placebo for the treatment of symptoms of OAB.
Detailed Description
The study included a three- or five-week screening period, followed by a 12-week treatment period during which patients received either one of three doses of dexmecamylamine or placebo twice daily, randomized in a ratio of 2:1:1:1 (placebo, low dose, mid dose, high dose), with a two-week follow-up period. A total of 768 subjects with overactive bladder were randomized into the double-blind treatment period of the study.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Overactive Bladder

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 2
Interventional Study Model
Parallel Assignment
Masking
ParticipantInvestigator
Allocation
Randomized
Enrollment
1635 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Placebo
Arm Type
Placebo Comparator
Arm Description
One tablet of placebo to be administered orally twice a day.
Arm Title
0.5 mg dexmecamylamine (TC-5214)
Arm Type
Experimental
Arm Description
One tablet of 0.5 mg dexmecamylamine to be administered orally twice a day.
Arm Title
1 mg dexmecamylamine (TC-5214)
Arm Type
Experimental
Arm Description
One tablet of 1 mg dexmecamylamine to be administered orally twice a day.
Arm Title
2 mg dexmecamylamine (TC-5214)
Arm Type
Experimental
Arm Description
One tablet of 2 mg dexmecamylamine to be administered orally twice a day.
Intervention Type
Drug
Intervention Name(s)
dexmecamylamine
Other Intervention Name(s)
TC-5214
Intervention Type
Drug
Intervention Name(s)
Placebo
Primary Outcome Measure Information:
Title
Change from baseline in micturition frequency per 24 hours
Description
Micturition: Any voiding episode recorded by the patient as "urinated" either with or without incontinence.
Time Frame
12 weeks
Title
Change from baseline in urinary urge incontinence (UUI) episodes per 24 hours
Time Frame
12 weeks
Secondary Outcome Measure Information:
Title
Change from baseline in the volume voided per micturition
Time Frame
12 weeks
Title
Change from baseline in nocturia per 24 hours
Description
Nocturia: A micturition that wakes the subject from sleep between the time the subject went to bed and the time the subject woke up.
Time Frame
12 weeks
Title
Clinical Global Impression of Improvement (CGI-I)
Time Frame
12 weeks
Title
Change from baseline in Patient Perception of Bladder Condition (PPBC)
Time Frame
12 weeks
Title
Change from baseline in the Urgency Questionnaire
Time Frame
12 weeks
Title
Change from baseline in disease specific quality of life (OABq)
Time Frame
12 weeks

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Verified medical history of overactive bladder for at least 6 months Capable of walking unassisted to use the bathroom Able to measure voided urine volume and complete the diary without assistance If the subject is currently being treated with an OAB medication, the subject is willing to discontinue OAB medications while participating in this study Exclusion Criteria: Diagnosis of a neurological disease affecting bladder function Stress incontinence, insensate incontinence, overflow incontinence or incontinence due to urinary fistula History of incomplete bladder emptying, bladder outflow obstruction or post-void residual bladder volume > 150 mL Males with benign prostatic hyperplasia or with a prostate-specific antigen (PSA) of 4 ng/mL or more Other urinary tract pathology such as malignancy, ureteric reflux, bladder stone, uninvestigated hematuria, urethral stricture, or cystitis Prior treatment with intravesical or intraprostatic botulinum toxin in the last 2 years Myasthenia gravis Angle closure glaucoma Current implantation of interstim electrodes or vaginal surgical mesh Presence of a clinically significant medical condition at any time during the study Presence of clinically significant abnormalities in laboratory findings, physical exam findings or vital signs Participated in an investigational drug trial within 3 months of screening
Facility Information:
Facility Name
Simon-Williamson Clinic, P.C.
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35209
Country
United States
Facility Name
Physician's Resource Group
City
Dothan
State/Province
Alabama
ZIP/Postal Code
36305
Country
United States
Facility Name
Coastal Clinical Research, Inc.
City
Mobile
State/Province
Alabama
ZIP/Postal Code
33324
Country
United States
Facility Name
Coastal Clinical Research, Inc
City
Mobile
State/Province
Alabama
ZIP/Postal Code
36608
Country
United States
Facility Name
Mobile Ob-Gyn, P.C.
City
Mobile
State/Province
Alabama
ZIP/Postal Code
36608
Country
United States
Facility Name
Radiant Research, Inc.
City
Chandler
State/Province
Arizona
ZIP/Postal Code
85224
Country
United States
Facility Name
Clinical Trials of Arizona, Inc.
City
Glendale
State/Province
Arizona
ZIP/Postal Code
85306
Country
United States
Facility Name
Beach Clinical Studies
City
Phoenix
State/Province
Arizona
ZIP/Postal Code
85051
Country
United States
Facility Name
Radiant Research, Inc.
City
Scottsdale
State/Province
Arizona
ZIP/Postal Code
85251
Country
United States
Facility Name
Genova Clinical Research, Inc.
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85704
Country
United States
Facility Name
Radiant Research, Inc.
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85710
Country
United States
Facility Name
Lynn Institute of the Ozarks
City
Little Rock
State/Province
Arkansas
ZIP/Postal Code
72205
Country
United States
Facility Name
Atlantic Urology Medical Group
City
Long Beach
State/Province
California
ZIP/Postal Code
90806
Country
United States
Facility Name
Adam D. Karnes, MD
City
Los Angeles
State/Province
California
ZIP/Postal Code
90036
Country
United States
Facility Name
Tri Valley Urology Medical Group
City
Murrieta
State/Province
California
ZIP/Postal Code
92562
Country
United States
Facility Name
Center for Clinical Trials, LLC
City
Paramount
State/Province
California
ZIP/Postal Code
90723
Country
United States
Facility Name
Northern California Research
City
Sacramento
State/Province
California
ZIP/Postal Code
95821
Country
United States
Facility Name
San Diego Sexual Medicine
City
San Diego
State/Province
California
ZIP/Postal Code
92120
Country
United States
Facility Name
Genesis Research
City
San Diego
State/Province
California
ZIP/Postal Code
92123
Country
United States
Facility Name
Westlake Medical Research
City
Thousand Oaks
State/Province
California
ZIP/Postal Code
91360
Country
United States
Facility Name
InFocus Clinical Research
City
Denver
State/Province
Colorado
ZIP/Postal Code
80211
Country
United States
Facility Name
Horizons Clinical Research Center, LLC
City
Denver
State/Province
Colorado
ZIP/Postal Code
80220
Country
United States
Facility Name
Women's Health Specialty Care
City
Farmington
State/Province
Connecticut
ZIP/Postal Code
06032
Country
United States
Facility Name
Connecticut Clinical Research Center, LLC
City
Middlebury
State/Province
Connecticut
ZIP/Postal Code
06762
Country
United States
Facility Name
South Florida Medical Research
City
Aventura
State/Province
Florida
ZIP/Postal Code
33180
Country
United States
Facility Name
Meridien Reseach
City
Brooksville
State/Province
Florida
ZIP/Postal Code
34601
Country
United States
Facility Name
Tampa Bay Medical Research
City
Clearwater
State/Province
Florida
ZIP/Postal Code
33761
Country
United States
Facility Name
3H Clinical Research Corporation
City
Coral Springs
State/Province
Florida
ZIP/Postal Code
33065
Country
United States
Facility Name
Palm Spring Research Institute
City
Hialeah
State/Province
Florida
ZIP/Postal Code
33012
Country
United States
Facility Name
American Medical Research Institute
City
Kissimmee
State/Province
Florida
ZIP/Postal Code
34741
Country
United States
Facility Name
Altus Research
City
Lake Worth
State/Province
Florida
ZIP/Postal Code
33461
Country
United States
Facility Name
Sunrise Medical Research
City
Lauderdale Lakes
State/Province
Florida
ZIP/Postal Code
33319
Country
United States
Facility Name
Suncoast Clinical Research, Inc.
City
New Port Richey
State/Province
Florida
ZIP/Postal Code
34652
Country
United States
Facility Name
Advanced Research Institute, Inc.
City
New Port Richey
State/Province
Florida
ZIP/Postal Code
34653
Country
United States
Facility Name
Clinical Research of Central Florida
City
Plant City
State/Province
Florida
ZIP/Postal Code
33563
Country
United States
Facility Name
Lakeview Medical Research
City
Summerfield
State/Province
Florida
ZIP/Postal Code
34491
Country
United States
Facility Name
Southeastern Research Group, Inc.
City
Tallahassee
State/Province
Florida
ZIP/Postal Code
32308
Country
United States
Facility Name
Palm Beach Research Center
City
West Palm Beach
State/Province
Florida
ZIP/Postal Code
33409
Country
United States
Facility Name
Clinical Research of Central Florida
City
Winter Haven
State/Province
Florida
ZIP/Postal Code
33880
Country
United States
Facility Name
Atlanta Medical Research Institute
City
Alpharetta
State/Province
Georgia
ZIP/Postal Code
30005
Country
United States
Facility Name
Radiant Reseach, Inc.
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30342
Country
United States
Facility Name
Southeast Regional Research Group
City
Columbus
State/Province
Georgia
ZIP/Postal Code
31904
Country
United States
Facility Name
Perimeter North Medical Research, Inc.
City
Roswell
State/Province
Georgia
ZIP/Postal Code
30076
Country
United States
Facility Name
Fellows Research Alliance, Inc.
City
Savannah
State/Province
Georgia
ZIP/Postal Code
31406
Country
United States
Facility Name
North Georgia Clinical Research
City
Woodstock
State/Province
Georgia
ZIP/Postal Code
30189
Country
United States
Facility Name
North Idaho Urology
City
Coeur d'Alene
State/Province
Idaho
ZIP/Postal Code
83814
Country
United States
Facility Name
Radiant Research, Inc.
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60654
Country
United States
Facility Name
Clinical Investigation Specialists, Inc.
City
Gurnee
State/Province
Illinois
ZIP/Postal Code
60031
Country
United States
Facility Name
First Urology PSC
City
Jeffersonville
State/Province
Indiana
ZIP/Postal Code
47130
Country
United States
Facility Name
Deaconess Clinic Gateway Health Center
City
Newburgh
State/Province
Indiana
ZIP/Postal Code
47630
Country
United States
Facility Name
Heartland Research Associates, LLC
City
Augusta
State/Province
Kansas
ZIP/Postal Code
67010
Country
United States
Facility Name
Heartland Research Associates, LLC
City
Newton
State/Province
Kansas
ZIP/Postal Code
67114
Country
United States
Facility Name
GTC Research
City
Shawnee
State/Province
Kansas
ZIP/Postal Code
66218
Country
United States
Facility Name
Heartland Research Associates, LLC
City
Wichita
State/Province
Kansas
ZIP/Postal Code
67207
Country
United States
Facility Name
Bluegrass Clinical Research
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40291
Country
United States
Facility Name
Research Integrity, LLC
City
Owensboro
State/Province
Kentucky
ZIP/Postal Code
42303
Country
United States
Facility Name
Regional Urology, LLC
City
Shreveport
State/Province
Louisiana
ZIP/Postal Code
71106
Country
United States
Facility Name
Willis-Knighton Physician Network
City
Shreveport
State/Province
Louisiana
ZIP/Postal Code
71115
Country
United States
Facility Name
Mid Atlantic Urology Associates, LLC
City
Greenbelt
State/Province
Maryland
ZIP/Postal Code
20770
Country
United States
Facility Name
Boston Clinical Trials, Inc.
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02131
Country
United States
Facility Name
Beacon Clinical Research, LLC
City
Brockton
State/Province
Massachusetts
ZIP/Postal Code
02301
Country
United States
Facility Name
Bay State Clinical Trials, Inc.
City
Watertown
State/Province
Massachusetts
ZIP/Postal Code
02472
Country
United States
Facility Name
Family Medicine Specialists, PC
City
Grand Rapids
State/Province
Michigan
ZIP/Postal Code
49544
Country
United States
Facility Name
Beyer Research
City
Kalamazoo
State/Province
Michigan
ZIP/Postal Code
49009
Country
United States
Facility Name
Westside Family Medical Center, PC
City
Kalamazoo
State/Province
Michigan
ZIP/Postal Code
49009
Country
United States
Facility Name
William Beaumont Hospital
City
Royal Oak
State/Province
Michigan
ZIP/Postal Code
48073
Country
United States
Facility Name
Saginaw Valley Medical Reseach Group, LLC
City
Saginaw
State/Province
Michigan
ZIP/Postal Code
48604
Country
United States
Facility Name
Radiant Research, Inc.
City
Edina
State/Province
Minnesota
ZIP/Postal Code
55435
Country
United States
Facility Name
Metro Urology
City
Woodbury
State/Province
Minnesota
ZIP/Postal Code
55125
Country
United States
Facility Name
Mississippi Medical Research, LLC
City
Carriere
State/Province
Mississippi
ZIP/Postal Code
39426
Country
United States
Facility Name
Center for Pharmaceutical Research
City
Kansas City
State/Province
Missouri
ZIP/Postal Code
64114
Country
United States
Facility Name
Radiant Research, Inc.
City
St. Louis
State/Province
Missouri
ZIP/Postal Code
63141
Country
United States
Facility Name
Montana Health Research Institute, Inc.
City
Billings
State/Province
Montana
ZIP/Postal Code
59102
Country
United States
Facility Name
Five Valleys Urology
City
Missoula
State/Province
Montana
ZIP/Postal Code
59808
Country
United States
Facility Name
Women's Clinical of Lincoln, P.C.
City
Lincoln
State/Province
Nebraska
ZIP/Postal Code
68510
Country
United States
Facility Name
Quality Clinical Research, Inc.
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68114
Country
United States
Facility Name
Summit Medical Group
City
Berkeley Heights
State/Province
New Jersey
ZIP/Postal Code
07922
Country
United States
Facility Name
Comprehensive Clinical Research
City
Berlin
State/Province
New Jersey
ZIP/Postal Code
08009
Country
United States
Facility Name
Lawrence OB-GYN Clinical Research, LLC
City
Lawrenceville
State/Province
New Jersey
ZIP/Postal Code
08648
Country
United States
Facility Name
Delaware Valley Urology, LLC
City
Voorhees
State/Province
New Jersey
ZIP/Postal Code
08043
Country
United States
Facility Name
Albuquerque Clinical Trials, Inc.
City
Albuquerque
State/Province
New Mexico
ZIP/Postal Code
87102
Country
United States
Facility Name
SouthWest Clinical Research
City
Albuquerque
State/Province
New Mexico
ZIP/Postal Code
87109
Country
United States
Facility Name
The Urological Institute of Northeastern New York
City
Albany
State/Province
New York
ZIP/Postal Code
12208
Country
United States
Facility Name
Advanced Urology Centers of New York
City
Garden City
State/Province
New York
ZIP/Postal Code
11530
Country
United States
Facility Name
Premier Medical Group of the Hudson Valley, PC
City
Kingston
State/Province
New York
ZIP/Postal Code
12401
Country
United States
Facility Name
Manhattan Medical Research Practice PLLC
City
New York
State/Province
New York
ZIP/Postal Code
10016
Country
United States
Facility Name
Premier Medical Group of the Hudson Valley, PC
City
Poughkeepsie
State/Province
New York
ZIP/Postal Code
12601
Country
United States
Facility Name
Rochester Clinical Research, Inc.
City
Rochester
State/Province
New York
ZIP/Postal Code
14609
Country
United States
Facility Name
Wake Research Associates, LLC
City
Raleigh
State/Province
North Carolina
ZIP/Postal Code
27612
Country
United States
Facility Name
PMG Research of Wilmington
City
Wilmington
State/Province
North Carolina
ZIP/Postal Code
28401
Country
United States
Facility Name
Lyndhurst Clinical Research
City
Winston-Salem
State/Province
North Carolina
ZIP/Postal Code
27103
Country
United States
Facility Name
Radiant Research, Inc.
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45249
Country
United States
Facility Name
Rapid Medical Research, Inc.
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44122
Country
United States
Facility Name
The Cleveland Clinic
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44195
Country
United States
Facility Name
Radiant Research, Inc.
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43212
Country
United States
Facility Name
Physicians' Research, Inc.
City
Zanesville
State/Province
Ohio
ZIP/Postal Code
43701
Country
United States
Facility Name
Urologic Consultants of SE PA
City
Bala Cynwyd
State/Province
Pennsylvania
ZIP/Postal Code
19004
Country
United States
Facility Name
Altoona Center for Clinical Research
City
Duncansville
State/Province
Pennsylvania
ZIP/Postal Code
16635
Country
United States
Facility Name
Clinical Research of Philadelphia, LLC
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19114
Country
United States
Facility Name
Advanced Clinical Concepts
City
West Reading
State/Province
Pennsylvania
ZIP/Postal Code
19611
Country
United States
Facility Name
Greater Providence Clinical Research, LLC
City
Warwick
State/Province
Rhode Island
ZIP/Postal Code
02888
Country
United States
Facility Name
Radiant Research, Inc.
City
Anderson
State/Province
South Carolina
ZIP/Postal Code
29621
Country
United States
Facility Name
Fellows Research Alliance, Inc.
City
Bluffton
State/Province
South Carolina
ZIP/Postal Code
29910
Country
United States
Facility Name
Medical Research South, LLC
City
Charleston
State/Province
South Carolina
ZIP/Postal Code
29407
Country
United States
Facility Name
Coastal Carolina Research Center
City
Mount Pleasant
State/Province
South Carolina
ZIP/Postal Code
29464
Country
United States
Facility Name
Carolina Urologic Research Center
City
Myrtle Beach
State/Province
South Carolina
ZIP/Postal Code
29572
Country
United States
Facility Name
Hillcrest Clinical Research, LLC
City
Simpsonville
State/Province
South Carolina
ZIP/Postal Code
29681
Country
United States
Facility Name
Meridian Clinical Research
City
Dakota Dunes
State/Province
South Dakota
ZIP/Postal Code
57049
Country
United States
Facility Name
The Jackson Clinic
City
Jackson
State/Province
Tennessee
ZIP/Postal Code
38305
Country
United States
Facility Name
Advanced Therapeutics, Inc.
City
Johnson City
State/Province
Tennessee
ZIP/Postal Code
37601
Country
United States
Facility Name
Tennesse Women's Care
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37203
Country
United States
Facility Name
Tekton Research, Inc.
City
Austin
State/Province
Texas
ZIP/Postal Code
78745
Country
United States
Facility Name
DiscoverResearch, Inc.
City
Bryan
State/Province
Texas
ZIP/Postal Code
77802
Country
United States
Facility Name
Research Across America
City
Carrollton
State/Province
Texas
ZIP/Postal Code
75010
Country
United States
Facility Name
Research Across America
City
Dallas
State/Province
Texas
ZIP/Postal Code
75234
Country
United States
Facility Name
DCOL Center for Clinical Research
City
Longview
State/Province
Texas
ZIP/Postal Code
75605
Country
United States
Facility Name
Quality Research Inc.
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78209
Country
United States
Facility Name
Clinical Trials of Texas, Inc.
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Facility Name
Radiant Reseach, Inc.
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Facility Name
Wasatch Clinical Research
City
Salt Lake City
State/Province
Utah
ZIP/Postal Code
84107
Country
United States
Facility Name
The Group for Women
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23502
Country
United States
Facility Name
Clinical Research Associates of Tidewater, Inc.
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23507
Country
United States
Facility Name
Integrity Medical Research, LLC
City
Mountlake Terrace
State/Province
Washington
ZIP/Postal Code
98043
Country
United States
Facility Name
Valley Women's Clinic
City
Renton
State/Province
Washington
ZIP/Postal Code
98055
Country
United States
Facility Name
Seattle Women's Health, Research, Gynecology
City
Seattle
State/Province
Washington
ZIP/Postal Code
98105
Country
United States

12. IPD Sharing Statement

Learn more about this trial

Study Evaluating the Safety, Tolerability, and Efficacy of Dexmecamylamine (TC-5214) for Treatment of Overactive Bladder

We'll reach out to this number within 24 hrs