Efficacy of TOCT and (tDCS) for Gait Improvement in Patients With Chronic Stroke
Stroke
About this trial
This is an interventional treatment trial for Stroke focused on measuring Chronic Stroke, tDCS, transcranial direct current stimulation, task oriented circuit training, TOCT, gait training
Eligibility Criteria
Inclusion criteria:
- Males and females subjects. Age > 18 years, <75 years.
- Diagnosis of first ischemic stroke > 6 months.
- MMSE>24;
- FAC higher or equal to 4
Exclusion Criteria:
- Contraindications to tDCS: intracranial metal implants that can be stimulated, incorrectly positioned or over-heated by the electric current, presence of a history of epilepsy, frequent headaches or neck pain, implantable devices (ventriculoperitoneal shunts, pacemakers, intrathecal pumps, intracranial metal implants).
- Neurological or psychiatric pathology.
- Severe cardio-pulmonary, renal, hepatic diseases.
- Pregnancy.
Sites / Locations
- Ferrara University Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
real tDCS + TOCT
sham tDCS + TOCT
Every day will be given continuous stimulation duration of 15 minutes with intensity of 0.5 mA (for a current density of 60μA/cm2), generated by a constant current stimulator rechargeable batteries for 10 consecutive days after any rehabilitation treatment in the gym. Two sponge electrodes are placed, soaked in saline solution, fixed by an elastic band, the anode consists of an electrode oblong 8cm2 positioned at M1 area on the lower limb affection (following the medial sagittal axis, with the center of the electrode positioned at one centimeter laterally to the vertex) while the cathode (48cm2) is placed in the contralateral supraorbitale area as reference electrode. The current reaches 0.5mA and decreases with a ramp of 10 seconds.
Every day will be given a continuous low-intensity stimulation of 0.5mA (for a current density of 60μA/cm2) only for 10 seconds at the beginning and at the end of the stimulation for 10 consecutive days after any rehabilitative treatment. The mounting of electrodes for sham stimulation is the same used for the experimental group.