Interpersonal Psychotherapy for Treatment Resistant Depression
Treatment Resistant Depression
About this trial
This is an interventional treatment trial for Treatment Resistant Depression focused on measuring Psychotherapy, Treatment Resistant Depression, depression
Eligibility Criteria
Inclusion Criteria:
- Primary diagnose of unipolar treatment resistant depression
Exclusion Criteria:
- Patients diagnose of: bipolar disorder, psychosis, high suicide risk, Intellectual disability, illicit drug dependence.
- Currently in or having received psychotherapy in the last 4 weeks
Sites / Locations
- Federal University of Rio Grande do Sul / Hospital de Clínicas de Porto Alegre (HCPA)Recruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
IPT+antidepressant drugs
Antidepressant Drugs
Interpersonal Psychotherapy protocol (IPT) consist of 16 sessions of manualized interpersonal psychotherapy for depression. Patients are allowed to reschedule 3 sessions if they miss their appointments. Antidepressant Drugs protocol consist of pharmacological management of depression, oriented by international guidelines, clinician´s free choice. Monotherapy or combinations are allowed. Antidepressant and drugs are: fluoxetine, sertraline, paroxetin, citalopram, escitalopram, fluvoxamine, venlafaxin, duloxetin, bupropion, lithium, risperidone, tranylcypromine, Imipramine, amitriptyline, clomipramine, nortriptyline, trazodone, mirtazapine, sulpiride.
Drugs protocol consist of pharmacological management of depression, oriented by international guidelines, clinician´s free choice. Antidepressant Drugs protocol consist of pharmacological management of depression, oriented by international guidelines, clinician´s free choice. Monotherapy or combinations are allowed. Antidepressant and drugs are: fluoxetine, sertraline, paroxetine, citalopram, escitalopram, fluvoxamine, venlafaxine, duloxetine, bupropion, lithium, risperidone, tranylcypromine, Imipramine, amitriptyline, clomipramine, nortriptyline, trazodone, mirtazapine, sulpiride.