Insulin Therapy and Falls Due to Orthostatic Hypotension
Orthostatic Hypotension, Diabetes, Syncope
About this trial
This is an interventional diagnostic trial for Orthostatic Hypotension focused on measuring Diabetes, Insulin, Orthostatic Hypotension, Falls, Syncope
Eligibility Criteria
Inclusion Criteria:
- All subjects must be 65 years of age or older
- All must have been diagnosed with Type 2 diabetes for at least 5 years
- All subjects must be insulin-naïve on recruitment
- All subjects must be eligible to start insulin therapy (long or intermediate acting) as determined by their diabetologist
Exclusion Criteria:
- Anemia, as determined by serum hematocrit
- Abnormal liver function tests
- Elevated creatinine
- Smoker
- Musculoskeletal or neurological condition that would preclude tilt table testing or orthostatic vitals
Sites / Locations
- Gerontology Research Lab, Dept. of Medicine, Vancouver Coastal Health Research Institute, VGH Research Pavilion, Room 186-828 West 10th Avenue
Arms of the Study
Arm 1
Arm 2
Other
Other
Before Initiation of Insulin Therapy
After Initiation of Insulin Therapy
Study sessions will occur before the initiation of insulin therapy (no insulin). Initiation of insulin administration will be determined as part of standard of care by the subjects diabetologist in the VGH Diabetes Centre and not as part of participation in this study.
Study session will take place 2-4 weeks after the initiation of insulin therapy. Initiation of insulin administration will be determined as part of standard of care by the subjects diabetologist in the VGH Diabetes Centre and not as part of participation in this study.