Back to results

Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction (PARAGON-HF)

Primary Purpose

Heart Failure With Preserved Ejection Fraction

Status

Completed

Phase

Phase 3

Locations

International

Study Type

Interventional

Intervention

LCZ696

Valsartan

About this trial

This is an interventional treatment trial for Heart Failure With Preserved Ejection Fraction focused on measuring Heart failure, preserved ejection fraction, diastolic heart failure

Eligibility Criteria

50 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

Left ventricular ejection fraction (LVEF) ≥45% by echo during screening epoch or within 6 months prior to study entry.
Symptom(s) of heart failure (HF) and requiring treatment with diuretic(s) for HF at least 30 days prior to study entry.
Current symptom(s) of HF (NYHA class II-IV)
Structural heart disease (left atrial enlargement or left ventricular hypertrophy) documented by echocardiogram.
Elevated NT-proBNP

Exclusion Criteria:

Any prior measurement of LVEF < 40%.
Acute coronary syndrome (including MI), cardiac surgery, other major CV surgery within 3 months , or urgent percutaneous coronary intervention within 3 months or and elective PCI within 30 days prior to entry.
Any clinical event within the 6 months prior to entry could have reduced the LVEF (e.g., MI, CABG), unless an echo measurement performed after the event confirms a LVEF ≥45%.
Current acute decompensated HF requiring therapy.
Patients who require treatment with 2 or more of the following: an angiotensin converting enzyme inhibitor (ACEI), an angiotensin receptor blocker (ARB) or a renin inhibitor.
Alternative reason for shortness of breath such as: significant pulmonary disease or severe COPD, hemoglobin (Hgb) <10 g/dl, or body mass index (BMI) > 40 kg/m2.
Systolic blood pressure (SBP) ≥ 180 mmHg at entry, or SBP >150 mmHg and <180 mmHg at entry unless the patient is receiving 3 or more antihypertensive drugs, or SBP < 110 mmHg at entry.

Other protocol-defined inclusion/exclusion criteria may apply.

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

LCZ696

Valsartan

Arm Description

Single Blind Run-in Period (3-8 weeks): Patients will start on Valsartan 80 mg b.i.d. for 1-2 weeks followed by LCZ696 100 mg b.i.d. for 2-4 weeks prior to randomization into the Double Blind period (up to 57 months). Patients can only be randomized from the run-in period if they meet all of the run-in safety criteria. Target dose of LCZ696 during the double blind period is 200 mg b.i.d.

Single Blind Run-in Period (3-8 weeks): Patients will start on Valsartan 80 mg b.i.d. for 1-2 weeks followed by LCZ696 100 mg b.i.d. for 2-4 weeks prior to randomization into the Double Blind period (up to 57 months). Patients can only be randomized from the run-in period if they meet all of the run-in safety criteria. Target dose of Valsartan during the double blind period is 160 mg b.i.d.

Outcomes

Primary Outcome Measures

Cumulative Number of Primary Composite Events of Cardiovascular (CV) Death and Total (First and Recurrent) HF Hospitalizations.

The primary objective of this study is to compare LCZ696 to valsartan in reducing the rate of the composite endpoint of CV death and total (first and recurrent) HF hospitalizations, in HF patients (New York Heart Association [NYHA] Class II-IV) with preserved ejection fraction (left ventricular ejection fraction [LVEF] ≥45%). The treatment arm with the lower rate of events will be deemed as having a successful response.

Secondary Outcome Measures

Change in the Clinical Summary Score From Baseline to Month 8 by Kansas City Cardiomyopathy Questionnaire (KCCQ)

The KCCQ is a validated instrument for self-assessment of quality of life and health status in heart failure (HF) patients. The clinical summary score, which is derived from the physical limitations and heart failure (HF) symptoms domains of the KCCQ is a valid measure for assessing the patient's health aspects that may be influenced by CV medications. Scores are transformed to a range of 0-100, in which higher scores reflect better health status. Evaluation of change from baseline to month 8 in KCCQ a most sensitive, specific, and responsive health-related quality of life measure for heart failure symptoms and physical limitations.

Change From Baseline to Month 8 in New York Heart Association (NYHA) Functional Class

Evaluation of change from baseline to Month 8 in NYHA functional class, a well established grading scale used to classify a heart failure's (HF) patients' level of functionality based on the signs and symptoms of HF exhibited by the patient.

Participants With First Occurrence of a Composite Renal Endpoint

Analyis of composite renal endpoint defined as renal death, or reaching ESRD, or ≥50% decline in eGFR relative to baseline, using Cox's proportional hazards model.

All-cause Mortality

Analysis for all-cause mortality using Cox's proportional hazards model.

Full Information

NCT ID

NCT01920711

First Posted

August 8, 2013

Last Updated

September 8, 2020

Sponsor

Novartis Pharmaceuticals

1. Study Identification

Unique Protocol Identification Number

NCT01920711

Brief Title

Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction

Acronym

PARAGON-HF

Official Title

A Multicenter, Randomized, Double-blind, Parallel Group, Active-controlled Study to Evaluate the Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients (NYHA Class II-IV) With Preserved Ejection Fraction (PARAGON-HF)

Study Type

Interventional

2. Study Status

Record Verification Date

September 2020

Overall Recruitment Status

Completed

Study Start Date

July 18, 2014 (Actual)

Primary Completion Date

June 7, 2019 (Actual)

Study Completion Date

June 7, 2019 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

Novartis Pharmaceuticals

4. Oversight

Studies a U.S. FDA-regulated Drug Product

Yes

Studies a U.S. FDA-regulated Device Product

Data Monitoring Committee

Yes

5. Study Description

Brief Summary

The purpose of this study was to evaluate the effect of LCZ696 compared to valsartan in the reduction of cardiovascular death and heart failure(HF) hospitalizations in patients with HF with preserved ejection fraction.

Detailed Description

This was a multicenter, randomized, double-blind, parallel group, active-controlled, study to evaluate the efficacy and safety of sacubitril/valsartan compared to valsartan, on morbidity and mortality in heart failure patients (NYHA Class II-IV) with preserved ejection fraction. Specifically, the study evaluated the effect of sacubitril/valsartan compared to the active comparator valsartan in the reduction of the rate of CV death and total HF hospitalizations in patients with HFpEF. The trial consisted of two periods: (1) a single-blind treatment run-in epoch that lasted from 3 to 8 weeks, in which patients received valsartan 80 mg bid, followed by sacubitril/valsartan 100 mg bid and (2) a double-blind randomized treatment epoch (sacubitril/valsartan 200 mg bid or valsartan 160 mg bid). In this study, investigators were responsible for assessing and submitting all events which could potentially fulfill the criteria for the primary, secondary, or other clinical endpoints to a Clinical Endpoint Committee (CEC). Investigator reported events were assessed by the CEC for adjudication. For angioedema or angioedema-like events, investigators completed an Adjudication Questionnaire for an Angioedema-like Event form. All angioedema reports were forwarded to an Angioedema Adjudication Committee (AAC) by Novartis for assessment.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Heart Failure With Preserved Ejection Fraction

Keywords

Heart failure, preserved ejection fraction, diastolic heart failure

7. Study Design

Primary Purpose

Treatment

Study Phase

Phase 3

Interventional Study Model

Parallel Assignment

Masking

ParticipantInvestigator

Allocation

Randomized

Enrollment

4822 (Actual)

8. Arms, Groups, and Interventions

Arm Title

LCZ696

Arm Type

Experimental

Arm Description

Arm Title

Valsartan

Arm Type

Active Comparator

Arm Description

Single Blind Run-in Period (3-8 weeks): Patients will start on Valsartan 80 mg b.i.d. for 1-2 weeks followed by LCZ696 100 mg b.i.d. for 2-4 weeks prior to randomization into the Double Blind period (up to 57 months). Patients can only be randomized from the run-in period if they meet all of the run-in safety criteria. Target dose of Valsartan during the double blind period is 160 mg b.i.d.

Intervention Type

Drug

Intervention Name(s)

LCZ696

Intervention Description

LCZ696 50mg, 100mg and 200 mg dosage strengths will be available for dose adjustments.

Intervention Type

Drug

Intervention Name(s)

Valsartan

Intervention Description

Valsartan 40mg, 80mg and 160mg dosage strengths will be available for dose adjustments.

Primary Outcome Measure Information:

Title

Cumulative Number of Primary Composite Events of Cardiovascular (CV) Death and Total (First and Recurrent) HF Hospitalizations.

Description

Time Frame

Total follow up time (up to 57 months)

Secondary Outcome Measure Information:

Title

Change in the Clinical Summary Score From Baseline to Month 8 by Kansas City Cardiomyopathy Questionnaire (KCCQ)

Description

Time Frame

Baseline, 8 months

Title

Change From Baseline to Month 8 in New York Heart Association (NYHA) Functional Class

Description

Time Frame

Baseline, 8 months

Title

Participants With First Occurrence of a Composite Renal Endpoint

Description

Analyis of composite renal endpoint defined as renal death, or reaching ESRD, or ≥50% decline in eGFR relative to baseline, using Cox's proportional hazards model.

Time Frame

Randomization to total follow-up time (up to 57 months)

Title

All-cause Mortality

Description

Analysis for all-cause mortality using Cox's proportional hazards model.

Time Frame

Randomization to total follow up time (up to 57 months)

10. Eligibility

Sex

All

Minimum Age & Unit of Time

50 Years

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria: Left ventricular ejection fraction (LVEF) ≥45% by echo during screening epoch or within 6 months prior to study entry. Symptom(s) of heart failure (HF) and requiring treatment with diuretic(s) for HF at least 30 days prior to study entry. Current symptom(s) of HF (NYHA class II-IV) Structural heart disease (left atrial enlargement or left ventricular hypertrophy) documented by echocardiogram. Elevated NT-proBNP Exclusion Criteria: Any prior measurement of LVEF < 40%. Acute coronary syndrome (including MI), cardiac surgery, other major CV surgery within 3 months , or urgent percutaneous coronary intervention within 3 months or and elective PCI within 30 days prior to entry. Any clinical event within the 6 months prior to entry could have reduced the LVEF (e.g., MI, CABG), unless an echo measurement performed after the event confirms a LVEF ≥45%. Current acute decompensated HF requiring therapy. Patients who require treatment with 2 or more of the following: an angiotensin converting enzyme inhibitor (ACEI), an angiotensin receptor blocker (ARB) or a renin inhibitor. Alternative reason for shortness of breath such as: significant pulmonary disease or severe COPD, hemoglobin (Hgb) <10 g/dl, or body mass index (BMI) > 40 kg/m2. Systolic blood pressure (SBP) ≥ 180 mmHg at entry, or SBP >150 mmHg and <180 mmHg at entry unless the patient is receiving 3 or more antihypertensive drugs, or SBP < 110 mmHg at entry. Other protocol-defined inclusion/exclusion criteria may apply.

Overall Study Officials:

First Name & Middle Initial & Last Name & Degree

Novartis Pharmaceuticals

Organizational Affiliation

Novartis Pharmaceuticals

Official's Role

Study Director

Facility Information:

Facility Name

Novartis Investigative Site

City

Huntsville

State/Province

Alabama

ZIP/Postal Code

35801

Country

United States

Facility Name

Novartis Investigative Site

City

Mobile

State/Province

Alabama

ZIP/Postal Code

36608

Country

United States

Facility Name

Novartis Investigative Site

City

Muscle Shoals

State/Province

Alabama

ZIP/Postal Code

35662

Country

United States

Facility Name

Novartis Investigative Site

City

Little Rock

State/Province

Arkansas

ZIP/Postal Code

72204

Country

United States

Facility Name

Novartis Investigative Site

City

Beverly Hills

State/Province

California

ZIP/Postal Code

90211

Country

United States

Facility Name

Novartis Investigative Site

City

Los Angeles

State/Province

California

ZIP/Postal Code

90073

Country

United States

Facility Name

Novartis Investigative Site

City

Northridge

State/Province

California

ZIP/Postal Code

91325

Country

United States

Facility Name

Novartis Investigative Site

City

Orange

State/Province

California

ZIP/Postal Code

92868

Country

United States

Facility Name

Novartis Investigative Site

City

San Diego

State/Province

California

ZIP/Postal Code

92161

Country

United States

Facility Name

Novartis Investigative Site

City

Santa Ana

State/Province

California

ZIP/Postal Code

92704

Country

United States

Facility Name

Novartis Investigative Site

City

Denver

State/Province

Colorado

ZIP/Postal Code

80220

Country

United States

Facility Name

Novartis Investigative Site

City

Hartford

State/Province

Connecticut

ZIP/Postal Code

06105

Country

United States

Facility Name

Novartis Investigative Site

City

New Haven

State/Province

Connecticut

ZIP/Postal Code

06520-8062

Country

United States

Facility Name

Novartis Investigative Site

City

Stamford

State/Province

Connecticut

ZIP/Postal Code

06905

Country

United States

Facility Name

Novartis Investigative Site

City

West Haven

State/Province

Connecticut

ZIP/Postal Code

06516

Country

United States

Facility Name

Novartis Investigative Site

City

Bradenton

State/Province

Florida

ZIP/Postal Code

34209

Country

United States

Facility Name

Novartis Investigative Site

City

Gainesville

State/Province

Florida

ZIP/Postal Code

32608

Country

United States

Facility Name

Novartis Investigative Site

City

Lake Worth

State/Province

Florida

ZIP/Postal Code

33461

Country

United States

Facility Name

Novartis Investigative Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33143

Country

United States

Facility Name

Novartis Investigative Site

City

Tallahassee

State/Province

Florida

ZIP/Postal Code

32308

Country

United States

Facility Name

Novartis Investigative Site

City

Atlanta

State/Province

Georgia

ZIP/Postal Code

30309

Country

United States

Facility Name

Novartis Investigative Site

City

Atlanta

State/Province

Georgia

ZIP/Postal Code

30310-1495

Country

United States

Facility Name

Novartis Investigative Site

City

Covington

State/Province

Georgia

ZIP/Postal Code

30014

Country

United States

Facility Name

Novartis Investigative Site

City

Cumming

State/Province

Georgia

ZIP/Postal Code

30041

Country

United States

Facility Name

Novartis Investigative Site

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60611

Country

United States

Facility Name

Novartis Investigative Site

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60637

Country

United States

Facility Name

Novartis Investigative Site

City

Evanston

State/Province

Illinois

ZIP/Postal Code

60201

Country

United States

Facility Name

Novartis Investigative Site

City

Hazel Crest

State/Province

Illinois

ZIP/Postal Code

60429

Country

United States

Facility Name

Novartis Investigative Site

City

Lombard

State/Province

Illinois

ZIP/Postal Code

60148

Country

United States

Facility Name

Novartis Investigative Site

City

Maywood

State/Province

Illinois

ZIP/Postal Code

60153

Country

United States

Facility Name

Novartis Investigative Site

City

Oakbrook Terrace

State/Province

Illinois

ZIP/Postal Code

60181

Country

United States

Facility Name

Novartis Investigative Site

City

Peoria

State/Province

Illinois

ZIP/Postal Code

61602

Country

United States

Facility Name

Novartis Investigative Site

City

Quincy

State/Province

Illinois

ZIP/Postal Code

62301

Country

United States

Facility Name

Novartis Investigative Site

City

Louisville

State/Province

Kentucky

ZIP/Postal Code

40206

Country

United States

Facility Name

Novartis Investigative Site

City

Baton Rouge

State/Province

Louisiana

ZIP/Postal Code

70808

Country

United States

Facility Name

Novartis Investigative Site

City

Hammond

State/Province

Louisiana

ZIP/Postal Code

70403

Country

United States

Facility Name

Novartis Investigative Site

City

Lafayette

State/Province

Louisiana

ZIP/Postal Code

70508

Country

United States

Facility Name

Novartis Investigative Site

City

Slidell

State/Province

Louisiana

ZIP/Postal Code

70458

Country

United States

Facility Name

Novartis Investigative Site

City

Biddeford

State/Province

Maine

ZIP/Postal Code

04005

Country

United States

Facility Name

Novartis Investigative Site

City

Portland

State/Province

Maine

ZIP/Postal Code

04102

Country

United States

Facility Name

Novartis Investigative Site

City

Baltimore

State/Province

Maryland

ZIP/Postal Code

21229

Country

United States

Facility Name

Novartis Investigative Site

City

Baltimore

State/Province

Maryland

ZIP/Postal Code

21287

Country

United States

Facility Name

Novartis Investigative Site

City

Columbia

State/Province

Maryland

ZIP/Postal Code

21044

Country

United States

Facility Name

Novartis Investigative Site

City

Boston

State/Province

Massachusetts

ZIP/Postal Code

02118

Country

United States

Facility Name

Novartis Investigative Site

City

Boston

State/Province

Massachusetts

Country

United States

Facility Name

Novartis Investigative Site

City

Ann Arbor

State/Province

Michigan

ZIP/Postal Code

48105

Country

United States

Facility Name

Novartis Investigative Site

City

Detroit

State/Province

Michigan

ZIP/Postal Code

48202

Country

United States

Facility Name

Novartis Investigative Site

City

Grand Blanc

State/Province

Michigan

ZIP/Postal Code

48439

Country

United States

Facility Name

Novartis Investigative Site

City

Saginaw

State/Province

Michigan

ZIP/Postal Code

48601

Country

United States

Facility Name

Novartis Investigative Site

City

Minneapolis

State/Province

Minnesota

ZIP/Postal Code

55417

Country

United States

Facility Name

Novartis Investigative Site

City

Minneapolis

State/Province

Minnesota

ZIP/Postal Code

55433

Country

United States

Facility Name

Novartis Investigative Site

City

Minneapolis

State/Province

Minnesota

ZIP/Postal Code

55455

Country

United States

Facility Name

Novartis Investigative Site

City

Saint Cloud

State/Province

Minnesota

ZIP/Postal Code

56303

Country

United States

Facility Name

Novartis Investigative Site

City

Saint Paul

State/Province

Minnesota

ZIP/Postal Code

55102

Country

United States

Facility Name

Novartis Investigative Site

City

Belzoni

State/Province

Mississippi

ZIP/Postal Code

39038

Country

United States

Facility Name

Novartis Investigative Site

City

Jackson

State/Province

Mississippi

ZIP/Postal Code

39216

Country

United States

Facility Name

Novartis Investigative Site

City

Saint Louis

State/Province

Missouri

ZIP/Postal Code

63110

Country

United States

Facility Name

Novartis Investigative Site

City

Saint Louis

State/Province

Missouri

ZIP/Postal Code

63136

Country

United States

Facility Name

Novartis Investigative Site

City

Kalispell

State/Province

Montana

ZIP/Postal Code

59901 3158

Country

United States

Facility Name

Novartis Investigative Site

City

Lincoln

State/Province

Nebraska

ZIP/Postal Code

68506

Country

United States

Facility Name

Novartis Investigative Site

City

Lebanon

State/Province

New Hampshire

ZIP/Postal Code

03756

Country

United States

Facility Name

Novartis Investigative Site

City

Morristown

State/Province

New Jersey

ZIP/Postal Code

07960

Country

United States

Facility Name

Novartis Investigative Site

City

New Brunswick

State/Province

New Jersey

ZIP/Postal Code

08901

Country

United States

Facility Name

Novartis Investigative Site

City

Ridgewood

State/Province

New Jersey

ZIP/Postal Code

07450

Country

United States

Facility Name

Novartis Investigative Site

City

Albuquerque

State/Province

New Mexico

ZIP/Postal Code

87102

Country

United States

Facility Name

Novartis Investigative Site

City

Bronx

State/Province

New York

ZIP/Postal Code

10467

Country

United States

Facility Name

Novartis Investigative Site

City

Brooklyn

State/Province

New York

ZIP/Postal Code

11215

Country

United States

Facility Name

Novartis Investigative Site

City

Buffalo

State/Province

New York

ZIP/Postal Code

14203

Country

United States

Facility Name

Novartis Investigative Site

City

Buffalo

State/Province

New York

ZIP/Postal Code

14215

Country

United States

Facility Name

Novartis Investigative Site

City

Flushing

State/Province

New York

ZIP/Postal Code

11355

Country

United States

Facility Name

Novartis Investigative Site

City

Kingston

State/Province

New York

ZIP/Postal Code

12401

Country

United States

Facility Name

Novartis Investigative Site

City

Northport

State/Province

New York

ZIP/Postal Code

11768

Country

United States

Facility Name

Novartis Investigative Site

City

Rochester

State/Province

New York

ZIP/Postal Code

14642

Country

United States

Facility Name

Novartis Investigative Site

City

Saratoga Springs

State/Province

New York

ZIP/Postal Code

12866

Country

United States

Facility Name

Novartis Investigative Site

City

Chapel Hill

State/Province

North Carolina

ZIP/Postal Code

27599-7075

Country

United States

Facility Name

Novartis Investigative Site

City

Winston-Salem

State/Province

North Carolina

ZIP/Postal Code

27157

Country

United States

Facility Name

Novartis Investigative Site

City

Grand Forks

State/Province

North Dakota

ZIP/Postal Code

58201

Country

United States

Facility Name

Novartis Investigative Site

City

Canton

State/Province

Ohio

ZIP/Postal Code

44710

Country

United States

Facility Name

Novartis Investigative Site

City

Marion

State/Province

Ohio

ZIP/Postal Code

43302

Country

United States

Facility Name

Novartis Investigative Site

City

Tulsa

State/Province

Oklahoma

ZIP/Postal Code

74133

Country

United States

Facility Name

Novartis Investigative Site

City

Portland

State/Province

Oregon

ZIP/Postal Code

97225

Country

United States

Facility Name

Novartis Investigative Site

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19107

Country

United States

Facility Name

Novartis Investigative Site

City

Yardley

State/Province

Pennsylvania

ZIP/Postal Code

19067

Country

United States

Facility Name

Novartis Investigative Site

City

Providence

State/Province

Rhode Island

ZIP/Postal Code

02908

Country

United States

Facility Name

Novartis Investigative Site

City

Warwick

State/Province

Rhode Island

ZIP/Postal Code

02886

Country

United States

Facility Name

Novartis Investigative Site

City

Charleston

State/Province

South Carolina

ZIP/Postal Code

29403

Country

United States

Facility Name

Novartis Investigative Site

City

Rapid City

State/Province

South Dakota

ZIP/Postal Code

57701

Country

United States

Facility Name

Novartis Investigative Site

City

Sioux Falls

State/Province

South Dakota

ZIP/Postal Code

57104

Country

United States

Facility Name

Novartis Investigative Site

City

Knoxville

State/Province

Tennessee

ZIP/Postal Code

37917

Country

United States

Facility Name

Novartis Investigative Site

City

Memphis

State/Province

Tennessee

ZIP/Postal Code

38104

Country

United States

Facility Name

Novartis Investigative Site

City

Nashville

State/Province

Tennessee

ZIP/Postal Code

37203

Country

United States

Facility Name

Novartis Investigative Site

City

Nashville

State/Province

Tennessee

ZIP/Postal Code

37212

Country

United States

Facility Name

Novartis Investigative Site

City

Beaumont

State/Province

Texas

ZIP/Postal Code

77702

Country

United States

Facility Name

Novartis Investigative Site

City

Dallas

State/Province

Texas

ZIP/Postal Code

75216

Country

United States

Facility Name

Novartis Investigative Site

City

Dallas

State/Province

Texas

ZIP/Postal Code

75231

Country

United States

Facility Name

Novartis Investigative Site

City

Dallas

State/Province

Texas

ZIP/Postal Code

75235

Country

United States

Facility Name

Novartis Investigative Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77030

Country

United States

Facility Name

Novartis Investigative Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77094

Country

United States

Facility Name

Novartis Investigative Site

City

Livingston

State/Province

Texas

ZIP/Postal Code

77351

Country

United States

Facility Name

Novartis Investigative Site

City

McKinney

State/Province

Texas

ZIP/Postal Code

75069

Country

United States

Facility Name

Novartis Investigative Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78234

Country

United States

Facility Name

Novartis Investigative Site

City

Tomball

State/Province

Texas

ZIP/Postal Code

77375

Country

United States

Facility Name

Novartis Investigative Site

City

Salt Lake City

State/Province

Utah

ZIP/Postal Code

84124

Country

United States

Facility Name

Novartis Investigative Site

City

Salt Lake City

State/Province

Utah

ZIP/Postal Code

84132

Country

United States

Facility Name

Novartis Investigative Site

City

White River Junction

State/Province

Vermont

ZIP/Postal Code

05009

Country

United States

Facility Name

Novartis Investigative Site

City

Seattle

State/Province

Washington

ZIP/Postal Code

98122

Country

United States

Facility Name

Novartis Investigative Site

City

Seattle

State/Province

Washington

ZIP/Postal Code

98195

Country

United States

Facility Name

Novartis Investigative Site

City

Madison

State/Province

Wisconsin

ZIP/Postal Code

53705

Country

United States

Facility Name

Novartis Investigative Site

City

Madison

State/Province

Wisconsin

ZIP/Postal Code

53792-1615

Country

United States

Facility Name

Novartis Investigative Site

City

Milwaukee

State/Province

Wisconsin

ZIP/Postal Code

53215

Country

United States

Facility Name

Novartis Investigative Site

City

Caba

State/Province

Buenos Aires

ZIP/Postal Code

1407

Country

Argentina

Facility Name

Novartis Investigative Site

City

Caba

State/Province

Buenos Aires

ZIP/Postal Code

C1056ABJ

Country

Argentina

Facility Name

Novartis Investigative Site

City

Caba

State/Province

Buenos Aires

ZIP/Postal Code

C1280AEB

Country

Argentina

Facility Name

Novartis Investigative Site

City

Quilmes

State/Province

Buenos Aires

ZIP/Postal Code

B1878GEG

Country

Argentina

Facility Name

Novartis Investigative Site

City

Ramos Mejia

State/Province

Buenos Aires

ZIP/Postal Code

B1704ETD

Country

Argentina

Facility Name

Novartis Investigative Site

City

Caba

State/Province

Capital Federal

ZIP/Postal Code

C1179AAB

Country

Argentina

Facility Name

Novartis Investigative Site

City

Posadas

State/Province

Misiones

ZIP/Postal Code

N3300AHX

Country

Argentina

Facility Name

Novartis Investigative Site

City

Ciudad de Salta

State/Province

Provincia De Salta

ZIP/Postal Code

A4406BPF

Country

Argentina

Facility Name

Novartis Investigative Site

City

Tucuman

State/Province

San Miguel De Tucuman

ZIP/Postal Code

T4000ICL

Country

Argentina

Facility Name

Novartis Investigative Site

City

Rosario

State/Province

Santa Fe

ZIP/Postal Code

2000

Country

Argentina

Facility Name

Novartis Investigative Site

City

Rosario

State/Province

Santa Fe

ZIP/Postal Code

3080

Country

Argentina

Facility Name

Novartis Investigative Site

City

Rosario

State/Province

Santa Fe

ZIP/Postal Code

S2000DSV

Country

Argentina

Facility Name

Novartis Investigative Site

City

Rosario

State/Province

Santa Fe

ZIP/Postal Code

S2000QID

Country

Argentina

Facility Name

Novartis Investigative Site

City

San Miguel de Tucuman

State/Province

Tucuman

ZIP/Postal Code

T4000IFL

Country

Argentina

Facility Name

Novartis Investigative Site

City

Buenos Aires

ZIP/Postal Code

C1425AGP

Country

Argentina

Facility Name

Novartis Investigative Site

City

Buenos Aires

ZIP/Postal Code

C1428DCO

Country

Argentina

Facility Name

Novartis Investigative Site

City

Caba

ZIP/Postal Code

C1119ACN

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5000AAX

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5000EVQ

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5009BSN

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5016KET

Country

Argentina

Facility Name

Novartis Investigative Site

City

Cordoba

ZIP/Postal Code

X5022CPU

Country

Argentina

Facility Name

Novartis Investigative Site

City

Formosa

ZIP/Postal Code

P3600

Country

Argentina

Facility Name

Novartis Investigative Site

City

San Luis

ZIP/Postal Code

D5702JRS

Country

Argentina

Facility Name

Novartis Investigative Site

City

Santa Fe

ZIP/Postal Code

S3000FWO

Country

Argentina

Facility Name

Novartis Investigative Site

City

Southport

State/Province

Queensland

ZIP/Postal Code

4215

Country

Australia

Facility Name

Novartis Investigative Site

City

Bedford Park

State/Province

South Australia

ZIP/Postal Code

5041

Country

Australia

Facility Name

Novartis Investigative Site

City

Bundoora

State/Province

Victoria

ZIP/Postal Code

3083

Country

Australia

Facility Name

Novartis Investigative Site

City

Epping

State/Province

Victoria

ZIP/Postal Code

3076

Country

Australia

Facility Name

Novartis Investigative Site

City

Geelong

State/Province

Victoria

ZIP/Postal Code

3220

Country

Australia

Facility Name

Novartis Investigative Site

City

Innsbruck

State/Province

Tyrol

ZIP/Postal Code

6020

Country

Austria

Facility Name

Novartis Investigative Site

City

Braunau

ZIP/Postal Code

A5280

Country

Austria

Facility Name

Novartis Investigative Site

City

Graz

ZIP/Postal Code

8020

Country

Austria

Facility Name

Novartis Investigative Site

City

Graz

ZIP/Postal Code

A-8036

Country

Austria

Facility Name

Novartis Investigative Site

City

Großgmain

ZIP/Postal Code

5084

Country

Austria

Facility Name

Novartis Investigative Site

City

Linz

ZIP/Postal Code

4010

Country

Austria

Facility Name

Novartis Investigative Site

City

Vienna

ZIP/Postal Code

1130

Country

Austria

Facility Name

Novartis Investigative Site

City

Wien

ZIP/Postal Code

A 1090

Country

Austria

Facility Name

Novartis Investigative Site

City

Aalst

ZIP/Postal Code

9300

Country

Belgium

Facility Name

Novartis Investigative Site

City

Antwerpen

ZIP/Postal Code

2060

Country

Belgium

Facility Name

Novartis Investigative Site

City

Brasschaat

ZIP/Postal Code

2930

Country

Belgium

Facility Name

Novartis Investigative Site

City

Bruxelles

ZIP/Postal Code

1200

Country

Belgium

Facility Name

Novartis Investigative Site

City

De Pinte

ZIP/Postal Code

9840

Country

Belgium

Facility Name

Novartis Investigative Site

City

Genk

ZIP/Postal Code

3600

Country

Belgium

Facility Name

Novartis Investigative Site

City

Gent

ZIP/Postal Code

9000

Country

Belgium

Facility Name

Novartis Investigative Site

City

Hasselt

ZIP/Postal Code

3500

Country

Belgium

Facility Name

Novartis Investigative Site

City

Huy

ZIP/Postal Code

4500

Country

Belgium

Facility Name

Novartis Investigative Site

City

Kortrijk

ZIP/Postal Code

8500

Country

Belgium

Facility Name

Novartis Investigative Site

City

Leuven

ZIP/Postal Code

3000

Country

Belgium

Facility Name

Novartis Investigative Site

City

Ottignies

ZIP/Postal Code

1340

Country

Belgium

Facility Name

Novartis Investigative Site

City

Goiania

State/Province

ZIP/Postal Code

74605-020

Country

Brazil

Facility Name

Novartis Investigative Site

City

Belo Horizonte

State/Province

ZIP/Postal Code

30150-221

Country

Brazil

Facility Name

Novartis Investigative Site

City

Uberlandia

State/Province

Minas Gerais

ZIP/Postal Code

38411 186

Country

Brazil

Facility Name

Novartis Investigative Site

City

Curitiba

State/Province

Parana

ZIP/Postal Code

80730 150

Country

Brazil

Facility Name

Novartis Investigative Site

City

Campina Grande do Sul

State/Province

ZIP/Postal Code

83430-000

Country

Brazil

Facility Name

Novartis Investigative Site

City

Porto Alegre

State/Province

ZIP/Postal Code

90035-003

Country

Brazil

Facility Name

Novartis Investigative Site

City

Porto Alegre

State/Province

ZIP/Postal Code

90880-480

Country

Brazil

Facility Name

Novartis Investigative Site

City

Liberdade

State/Province

Sao Paulo

ZIP/Postal Code

01504-001

Country

Brazil

Facility Name

Novartis Investigative Site

City

Blumenau

State/Province

ZIP/Postal Code

89020 430

Country

Brazil

Facility Name

Novartis Investigative Site

City

Campinas

State/Province

ZIP/Postal Code

13020-431

Country

Brazil

Facility Name

Novartis Investigative Site

City

Campinas

State/Province

ZIP/Postal Code

13060-904

Country

Brazil

Facility Name

Novartis Investigative Site

City

Ribeirao Preto

State/Province

ZIP/Postal Code

14055-370

Country

Brazil

Facility Name

Novartis Investigative Site

City

Sao Jose do Rio Preto

State/Province

ZIP/Postal Code

15090 000

Country

Brazil

Facility Name

Novartis Investigative Site

City

Sao Paulo

State/Province

ZIP/Postal Code

08270-070

Country

Brazil

Facility Name

Novartis Investigative Site

City

Burgas

ZIP/Postal Code

8127

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Pazardzhik

ZIP/Postal Code

4400

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Pleven

ZIP/Postal Code

5800

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Plovdiv

ZIP/Postal Code

4000

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Plovdiv

ZIP/Postal Code

4002

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Shumen

ZIP/Postal Code

9700

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Silistra

ZIP/Postal Code

7500

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Sliven

ZIP/Postal Code

8800

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Smolian

ZIP/Postal Code

4700

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Sofia

ZIP/Postal Code

1000

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Sofia

ZIP/Postal Code

1202

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Sofia

ZIP/Postal Code

1233

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Sofia

ZIP/Postal Code

1309

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Sofia

ZIP/Postal Code

1407

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Sofia

ZIP/Postal Code

1527

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Sofia

ZIP/Postal Code

1606

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Sofia

ZIP/Postal Code

1784

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Varna

ZIP/Postal Code

9010

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Veliko Tarnovo

ZIP/Postal Code

5000

Country

Bulgaria

Facility Name

Novartis Investigative Site

City

Calgary

State/Province

Alberta

ZIP/Postal Code

T2N 4Z6

Country

Canada

Facility Name

Novartis Investigative Site

City

Victoria

State/Province

British Columbia

ZIP/Postal Code

V8R4R2

Country

Canada

Facility Name

Novartis Investigative Site

City

St. John

State/Province

Newfoundland and Labrador

ZIP/Postal Code

A1B 3V6

Country

Canada

Facility Name

Novartis Investigative Site

City

Halifax

State/Province

Nova Scotia

ZIP/Postal Code

B3H 2Y9

Country

Canada

Facility Name

Novartis Investigative Site

City

Cambridge

State/Province

Ontario

ZIP/Postal Code

N1R 6V6

Country

Canada

Facility Name

Novartis Investigative Site

City

Hamilton

State/Province

Ontario

ZIP/Postal Code

L8L 2X2

Country

Canada

Facility Name

Novartis Investigative Site

City

Ottawa

State/Province

Ontario

ZIP/Postal Code

K1Y 4W7

Country

Canada

Facility Name

Novartis Investigative Site

City

Toronto

State/Province

Ontario

ZIP/Postal Code

M5B 1W8

Country

Canada

Facility Name

Novartis Investigative Site

City

Toronto

State/Province

Ontario

ZIP/Postal Code

M5G 1X5

Country

Canada

Facility Name

Novartis Investigative Site

City

Toronto

State/Province

Ontario

ZIP/Postal Code

M5S 1B2

Country

Canada

Facility Name

Novartis Investigative Site

City

Weston

State/Province

Ontario

ZIP/Postal Code

M9N 1W4

Country

Canada

Facility Name

Novartis Investigative Site

City

Montreal

State/Province

Quebec

ZIP/Postal Code

H1T 1C8

Country

Canada

Facility Name

Novartis Investigative Site

City

Montreal

State/Province

Quebec

ZIP/Postal Code

H3G 1A4

Country

Canada

Facility Name

Novartis Investigative Site

City

Montreal

State/Province

Quebec

ZIP/Postal Code

H3T 1E2

Country

Canada

Facility Name

Novartis Investigative Site

City

Sainte Foy

State/Province

Quebec

ZIP/Postal Code

G1V 4G5

Country

Canada

Facility Name

Novartis Investigative Site

City

Sherbrooke

State/Province

Quebec

ZIP/Postal Code

J1G 2E8

Country

Canada

Facility Name

Novartis Investigative Site

City

Thetford Mines

State/Province

Quebec

ZIP/Postal Code

G6G 2V4

Country

Canada

Facility Name

Novartis Investigative Site

City

Trois Rivieres

State/Province

Quebec

ZIP/Postal Code

G8Z 3R9

Country

Canada

Facility Name

Novartis Investigative Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100037

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100039

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100044

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100730

Country

China

Facility Name

Novartis Investigative Site

City

Chongqing

State/Province

Chongqing

ZIP/Postal Code

400010

Country

China

Facility Name

Novartis Investigative Site

City

Lanzhou

State/Province

Gansu

ZIP/Postal Code

730030

Country

China

Facility Name

Novartis Investigative Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

51000

Country

China

Facility Name

Novartis Investigative Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

510080

Country

China

Facility Name

Novartis Investigative Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

510515

Country

China

Facility Name

Novartis Investigative Site

City

Nanning

State/Province

Guangxi

ZIP/Postal Code

530021

Country

China

Facility Name

Novartis Investigative Site

City

Changsha

State/Province

Hunan

ZIP/Postal Code

410003

Country

China

Facility Name

Novartis Investigative Site

City

Nanjing

State/Province

Jiangsu

ZIP/Postal Code

210009

Country

China

Facility Name

Novartis Investigative Site

City

Nanjing

State/Province

Jiangsu

ZIP/Postal Code

210029

Country

China

Facility Name

Novartis Investigative Site

City

Suzhou

State/Province

Jiangsu

ZIP/Postal Code

215004

Country

China

Facility Name

Novartis Investigative Site

City

Wuxi

State/Province

Jiangsu

Country

China

Facility Name

Novartis Investigative Site

City

Nanchang

State/Province

Jiangxi

ZIP/Postal Code

330006

Country

China

Facility Name

Novartis Investigative Site

City

Changchun

State/Province

Jilin

ZIP/Postal Code

130022

Country

China

Facility Name

Novartis Investigative Site

City

Jilin

State/Province

Jilin

ZIP/Postal Code

132000

Country

China

Facility Name

Novartis Investigative Site

City

Shenyang

State/Province

Liaoning

ZIP/Postal Code

110003

Country

China

Facility Name

Novartis Investigative Site

City

Shenyang

State/Province

Liaoning

ZIP/Postal Code

110016

Country

China

Facility Name

Novartis Investigative Site

City

Shanghai

State/Province

Shanghai

ZIP/Postal Code

200032

Country

China

Facility Name

Novartis Investigative Site

City

Shanghai

State/Province

Shanghai

ZIP/Postal Code

200120

Country

China

Facility Name

Novartis Investigative Site

City

Shanghai

State/Province

Shanghai

Country

China

Facility Name

Novartis Investigative Site

City

Xi'an

State/Province

Shanxi

ZIP/Postal Code

710032

Country

China

Facility Name

Novartis Investigative Site

City

Xian

State/Province

Shanxi

ZIP/Postal Code

710061

Country

China

Facility Name

Novartis Investigative Site

City

Chengdu

State/Province

Sichuan

ZIP/Postal Code

610041

Country

China

Facility Name

Novartis Investigative Site

City

Tianjin

State/Province

Tianjin

ZIP/Postal Code

300121

Country

China

Facility Name

Novartis Investigative Site

City

Wulumuqi

State/Province

Xinjiang

ZIP/Postal Code

830054

Country

China

Facility Name

Novartis Investigative Site

City

Hangzhou

State/Province

Zhejiang

ZIP/Postal Code

310009

Country

China

Facility Name

Novartis Investigative Site

City

Hangzhou

State/Province

Zhejiang

ZIP/Postal Code

310013

Country

China

Facility Name

Novartis Investigative Site

City

Hangzhou

State/Province

Zhejiang

ZIP/Postal Code

310016

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

ZIP/Postal Code

100029

Country

China

Facility Name

Novartis Investigative Site

City

Beijing

ZIP/Postal Code

100034

Country

China

Facility Name

Novartis Investigative Site

City

Chongqing

ZIP/Postal Code

400037

Country

China

Facility Name

Novartis Investigative Site

City

Jinan

ZIP/Postal Code

250012

Country

China

Facility Name

Novartis Investigative Site

City

Nanjing

ZIP/Postal Code

210036

Country

China

Facility Name

Novartis Investigative Site

City

Shanghai

ZIP/Postal Code

200025

Country

China

Facility Name

Novartis Investigative Site

City

Shanghai

ZIP/Postal Code

200031

Country

China

Facility Name

Novartis Investigative Site

City

Shanghai

ZIP/Postal Code

200080

Country

China

Facility Name

Novartis Investigative Site

City

Medellin

State/Province

Antioquia

ZIP/Postal Code

050036

Country

Colombia

Facility Name

Novartis Investigative Site

City

Barranquilla

State/Province

Atlantico

Country

Colombia

Facility Name

Novartis Investigative Site

City

Barranquilla

ZIP/Postal Code

080020

Country

Colombia

Facility Name

Novartis Investigative Site

City

Barranquilla

Country

Colombia

Facility Name

Novartis Investigative Site

City

Florida Blanca

Country

Colombia

Facility Name

Novartis Investigative Site

City

Varazdin

State/Province

HRV

ZIP/Postal Code

42000

Country

Croatia

Facility Name

Novartis Investigative Site

City

Rijeka

ZIP/Postal Code

51000

Country

Croatia

Facility Name

Novartis Investigative Site

City

Zadar

ZIP/Postal Code

23000

Country

Croatia

Facility Name

Novartis Investigative Site

City

Zagreb

ZIP/Postal Code

10000

Country

Croatia

Facility Name

Novartis Investigative Site

City

Brandys nad Labem

State/Province

Czech Republic

ZIP/Postal Code

250 01

Country

Czechia

Facility Name

Novartis Investigative Site

City

Brno

State/Province

Czech Republic

ZIP/Postal Code

60200

Country

Czechia

Facility Name

Novartis Investigative Site

City

Ivancice

State/Province

Czech Republic

ZIP/Postal Code

66491

Country

Czechia

Facility Name

Novartis Investigative Site

City

Kladno

State/Province

Czech Republic

ZIP/Postal Code

272 80

Country

Czechia

Facility Name

Novartis Investigative Site

City

Liberec

State/Province

Czech Republic

ZIP/Postal Code

460 05

Country

Czechia

Facility Name

Novartis Investigative Site

City

Louny

State/Province

Czech Republic

Country

Czechia

Facility Name

Novartis Investigative Site

City

Ostrava

State/Province

Czech Republic

ZIP/Postal Code

70200

Country

Czechia

Facility Name

Novartis Investigative Site

City

Plzen

State/Province

Czech Republic

ZIP/Postal Code

30100

Country

Czechia

Facility Name

Novartis Investigative Site

City

Praha 4

State/Province

Czech Republic

ZIP/Postal Code

140 21

Country

Czechia

Facility Name

Novartis Investigative Site

City

Roznov pod Radhostem

State/Province

Czech Republic

ZIP/Postal Code

756 61

Country

Czechia

Facility Name

Novartis Investigative Site

City

Svitavy

State/Province

Czech Republic

ZIP/Postal Code

568 25

Country

Czechia

Facility Name

Novartis Investigative Site

City

Trebic

State/Province

Czech Republic

ZIP/Postal Code

674 01

Country

Czechia

Facility Name

Novartis Investigative Site

City

Usti nad Labem

State/Province

Czech Republic

ZIP/Postal Code

400 01

Country

Czechia

Facility Name

Novartis Investigative Site

City

Znojmo

State/Province

Czech Republic

ZIP/Postal Code

66902

Country

Czechia

Facility Name

Novartis Investigative Site

City

Policska

State/Province

CZE

ZIP/Postal Code

57201

Country

Czechia

Facility Name

Novartis Investigative Site

City

Praha 2

State/Province

CZE

ZIP/Postal Code

128 08

Country

Czechia

Facility Name

Novartis Investigative Site

City

Usti nad Labem

State/Province

CZE

ZIP/Postal Code

400 01

Country

Czechia

Facility Name

Novartis Investigative Site

City

CZE

ZIP/Postal Code

11000

Country

Czechia

Facility Name

Novartis Investigative Site

City

Kolin

ZIP/Postal Code

280 20

Country

Czechia

Facility Name

Novartis Investigative Site

City

Marianske lazne

ZIP/Postal Code

353 01

Country

Czechia

Facility Name

Novartis Investigative Site

City

Uherske Hradiste

ZIP/Postal Code

68601

Country

Czechia

Facility Name

Novartis Investigative Site

City

Esbjerg

ZIP/Postal Code

DK-6700

Country

Denmark

Facility Name

Novartis Investigative Site

City

Glostrup

ZIP/Postal Code

2600

Country

Denmark

Facility Name

Novartis Investigative Site

City

Herlev

ZIP/Postal Code

2730

Country

Denmark

Facility Name

Novartis Investigative Site

City

Hvidovre

ZIP/Postal Code

2650

Country

Denmark

Facility Name

Novartis Investigative Site

City

Randers

ZIP/Postal Code

8930

Country

Denmark

Facility Name

Novartis Investigative Site

City

Svendborg

ZIP/Postal Code

5700

Country

Denmark

Facility Name

Novartis Investigative Site

City

Viborg

ZIP/Postal Code

DK-8800

Country

Denmark

Facility Name

Novartis Investigative Site

City

Jyvaskyla

ZIP/Postal Code

40620

Country

Finland

Facility Name

Novartis Investigative Site

City

Oulu

ZIP/Postal Code

90220

Country

Finland

Facility Name

Novartis Investigative Site

City

Tampere

ZIP/Postal Code

33520

Country

Finland

Facility Name

Novartis Investigative Site

City

Bayonne

State/Province

Bayonne Cedex

ZIP/Postal Code

64109

Country

France

Facility Name

Novartis Investigative Site

City

Montpellier cedex 5

State/Province

Herault

ZIP/Postal Code

34059

Country

France

Facility Name

Novartis Investigative Site

City

Besancon Cedex

ZIP/Postal Code

25030

Country

France

Facility Name

Novartis Investigative Site

City

Beziers Cedex

ZIP/Postal Code

34525

Country

France

Facility Name

Novartis Investigative Site

City

Bordeaux Cedex

ZIP/Postal Code

33075

Country

France

Facility Name

Novartis Investigative Site

City

Grenoble

ZIP/Postal Code

38043

Country

France

Facility Name

Novartis Investigative Site

City

Lyon

ZIP/Postal Code

F-69001

Country

France

Facility Name

Novartis Investigative Site

City

Paris cedex 10

ZIP/Postal Code

75010

Country

France

Facility Name

Novartis Investigative Site

City

Poitiers

ZIP/Postal Code

86000

Country

France

Facility Name

Novartis Investigative Site

City

Pontoise

ZIP/Postal Code

F-95300

Country

France

Facility Name

Novartis Investigative Site

City

Rennes Cedex 9

ZIP/Postal Code

35033

Country

France

Facility Name

Novartis Investigative Site

City

Toulouse Cedex

ZIP/Postal Code

31059

Country

France

Facility Name

Novartis Investigative Site

City

Tourcoing

ZIP/Postal Code

59208

Country

France

Facility Name

Novartis Investigative Site

City

Vandoeuvre Les Nancy

ZIP/Postal Code

54511

Country

France

Facility Name

Novartis Investigative Site

City

Dresden

State/Province

Sachsen

ZIP/Postal Code

01099

Country

Germany

Facility Name

Novartis Investigative Site

City

Aachen

ZIP/Postal Code

52074

Country

Germany

Facility Name

Novartis Investigative Site

City

Bad Homburg

ZIP/Postal Code

61348

Country

Germany

Facility Name

Novartis Investigative Site

City

Bad Krozingen

ZIP/Postal Code

79189

Country

Germany

Facility Name

Novartis Investigative Site

City

Bamberg

ZIP/Postal Code

96049

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin Buch

ZIP/Postal Code

13125

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

10789

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

12157

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

12683

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

13086

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

13353

Country

Germany

Facility Name

Novartis Investigative Site

City

Berlin

ZIP/Postal Code

13405

Country

Germany

Facility Name

Novartis Investigative Site

City

Chemnitz

ZIP/Postal Code

09126

Country

Germany

Facility Name

Novartis Investigative Site

City

Chemnitz

ZIP/Postal Code

09130

Country

Germany

Facility Name

Novartis Investigative Site

City

Dessau-Roßlau

ZIP/Postal Code

06846

Country

Germany

Facility Name

Novartis Investigative Site

City

Dresden

ZIP/Postal Code

01277

Country

Germany

Facility Name

Novartis Investigative Site

City

Dresden

ZIP/Postal Code

01307

Country

Germany

Facility Name

Novartis Investigative Site

City

Dresden

ZIP/Postal Code

01309

Country

Germany

Facility Name

Novartis Investigative Site

City

Duisburg

ZIP/Postal Code

47137

Country

Germany

Facility Name

Novartis Investigative Site

City

Eilenburg

ZIP/Postal Code

D 04838

Country

Germany

Facility Name

Novartis Investigative Site

City

Elsterwerda

ZIP/Postal Code

04910

Country

Germany

Facility Name

Novartis Investigative Site

City

Essen

ZIP/Postal Code

45355

Country

Germany

Facility Name

Novartis Investigative Site

City

Frankfurt

ZIP/Postal Code

60594

Country

Germany

Facility Name

Novartis Investigative Site

City

Frankfurt

ZIP/Postal Code

65929

Country

Germany

Facility Name

Novartis Investigative Site

City

Hamburg

ZIP/Postal Code

20099

Country

Germany

Facility Name

Novartis Investigative Site

City

Hamburg

ZIP/Postal Code

20246

Country

Germany

Facility Name

Novartis Investigative Site

City

Hamburg

ZIP/Postal Code

22041

Country

Germany

Facility Name

Novartis Investigative Site

City

Hamburg

ZIP/Postal Code

22765

Country

Germany

Facility Name

Novartis Investigative Site

City

Hassloch

ZIP/Postal Code

67454

Country

Germany

Facility Name

Novartis Investigative Site

City

Heidenau

ZIP/Postal Code

01809

Country

Germany

Facility Name

Novartis Investigative Site

City

Heppenheim

ZIP/Postal Code

64646

Country

Germany

Facility Name

Novartis Investigative Site

City

Homburg

ZIP/Postal Code

66421

Country

Germany

Facility Name

Novartis Investigative Site

City

Ingelheim

ZIP/Postal Code

55218

Country

Germany

Facility Name

Novartis Investigative Site

City

Jena

ZIP/Postal Code

07740

Country

Germany

Facility Name

Novartis Investigative Site

City

Kassel

ZIP/Postal Code

34121

Country

Germany

Facility Name

Novartis Investigative Site

City

Kleve

ZIP/Postal Code

47533

Country

Germany

Facility Name

Novartis Investigative Site

City

Koblenz

ZIP/Postal Code

56068

Country

Germany

Facility Name

Novartis Investigative Site

City

Koeln

ZIP/Postal Code

51065

Country

Germany

Facility Name

Novartis Investigative Site

City

Leipzig

ZIP/Postal Code

04103

Country

Germany

Facility Name

Novartis Investigative Site

City

Loehne

ZIP/Postal Code

32584

Country

Germany

Facility Name

Novartis Investigative Site

City

Ludwigshafen

ZIP/Postal Code

67071

Country

Germany

Facility Name

Novartis Investigative Site

City

Lutherstadt Wittenberg

ZIP/Postal Code

06886

Country

Germany

Facility Name

Novartis Investigative Site

City

Lüneburg

ZIP/Postal Code

21339

Country

Germany

Facility Name

Novartis Investigative Site

City

Mainz

ZIP/Postal Code

55116

Country

Germany

Facility Name

Novartis Investigative Site

City

Meißen

ZIP/Postal Code

01662

Country

Germany

Facility Name

Novartis Investigative Site

City

Memmingen

ZIP/Postal Code

87700

Country

Germany

Facility Name

Novartis Investigative Site

City

Muehldorf Am Inn

ZIP/Postal Code

84453

Country

Germany

Facility Name

Novartis Investigative Site

City

Muehldorf

ZIP/Postal Code

84453

Country

Germany

Facility Name

Novartis Investigative Site

City

Muenster

ZIP/Postal Code

48149

Country

Germany

Facility Name

Novartis Investigative Site

City

Munchen

ZIP/Postal Code

81675

Country

Germany

Facility Name

Novartis Investigative Site

City

Munich

ZIP/Postal Code

80638

Country

Germany

Facility Name

Novartis Investigative Site

City

Nienburg

ZIP/Postal Code

31582

Country

Germany

Facility Name

Novartis Investigative Site

City

Northeim

ZIP/Postal Code

37154

Country

Germany

Facility Name

Novartis Investigative Site

City

Oschatz

ZIP/Postal Code

04758

Country

Germany

Facility Name

Novartis Investigative Site

City

Papenburg

ZIP/Postal Code

26871

Country

Germany

Facility Name

Novartis Investigative Site

City

Reinfeld

ZIP/Postal Code

23858

Country

Germany

Facility Name

Novartis Investigative Site

City

Riesa

ZIP/Postal Code

01589

Country

Germany

Facility Name

Novartis Investigative Site

City

Rodgau

ZIP/Postal Code

63110

Country

Germany

Facility Name

Novartis Investigative Site

City

Siegen

ZIP/Postal Code

57072

Country

Germany

Facility Name

Novartis Investigative Site

City

Ulm

ZIP/Postal Code

89077

Country

Germany

Facility Name

Novartis Investigative Site

City

Wermsdorf

ZIP/Postal Code

04779

Country

Germany

Facility Name

Novartis Investigative Site

City

Weyhe

ZIP/Postal Code

28844

Country

Germany

Facility Name

Novartis Investigative Site

City

Witten

ZIP/Postal Code

58455

Country

Germany

Facility Name

Novartis Investigative Site

City

Wuerzburg

ZIP/Postal Code

97080

Country

Germany

Facility Name

Novartis Investigative Site

City

Athens

State/Province

Attica

ZIP/Postal Code

15562

Country

Greece

Facility Name

Novartis Investigative Site

City

Athens

State/Province

ZIP/Postal Code

14233

Country

Greece

Facility Name

Novartis Investigative Site

City

Ioannina

State/Province

ZIP/Postal Code

455 00

Country

Greece

Facility Name

Novartis Investigative Site

City

Larissa

State/Province

ZIP/Postal Code

411 10

Country

Greece

Facility Name

Novartis Investigative Site

City

Athens

ZIP/Postal Code

115 27

Country

Greece

Facility Name

Novartis Investigative Site

City

Athens

ZIP/Postal Code

12462

Country

Greece

Facility Name

Novartis Investigative Site

City

Thessaloniki

ZIP/Postal Code

54642

Country

Greece

Facility Name

Novartis Investigative Site

City

Thessaloniki

ZIP/Postal Code

GR 54636

Country

Greece

Facility Name

Novartis Investigative Site

City

Guatemala City

ZIP/Postal Code

01010

Country

Guatemala

Facility Name

Novartis Investigative Site

City

Guatemala City

ZIP/Postal Code

01011

Country

Guatemala

Facility Name

Novartis Investigative Site

City

Guatemala City

ZIP/Postal Code

01015

Country

Guatemala

Facility Name

Novartis Investigative Site

City

Guatemala City

ZIP/Postal Code

10110

Country

Guatemala

Facility Name

Novartis Investigative Site

City

Zalaegerszeg

State/Province

Zala

ZIP/Postal Code

8900

Country

Hungary

Facility Name

Novartis Investigative Site

City

Budapest

ZIP/Postal Code

1042

Country

Hungary

Facility Name

Novartis Investigative Site

City

Budapest

ZIP/Postal Code

1085

Country

Hungary

Facility Name

Novartis Investigative Site

City

Budapest

ZIP/Postal Code

1134

Country

Hungary

Facility Name

Novartis Investigative Site

City

Budapest

ZIP/Postal Code

1145

Country

Hungary

Facility Name

Novartis Investigative Site

City

Budapest

ZIP/Postal Code

H 1096

Country

Hungary

Facility Name

Novartis Investigative Site

City

Cegled

ZIP/Postal Code

2700

Country

Hungary

Facility Name

Novartis Investigative Site

City

Kistarcsa

ZIP/Postal Code

2143

Country

Hungary

Facility Name

Novartis Investigative Site

City

Mako

ZIP/Postal Code

6900

Country

Hungary

Facility Name

Novartis Investigative Site

City

Nyiregyháza

ZIP/Postal Code

4400

Country

Hungary

Facility Name

Novartis Investigative Site

City

Pecs

ZIP/Postal Code

7623

Country

Hungary

Facility Name

Novartis Investigative Site

City

Pecs

ZIP/Postal Code

7635

Country

Hungary

Facility Name

Novartis Investigative Site

City

Pécs

ZIP/Postal Code

7623

Country

Hungary

Facility Name

Novartis Investigative Site

City

Szeged

ZIP/Postal Code

H 6725

Country

Hungary

Facility Name

Novartis Investigative Site

City

Szekesfehervar

ZIP/Postal Code

H-8000

Country

Hungary

Facility Name

Novartis Investigative Site

City

Guntur

State/Province

Andhra Pradesh

ZIP/Postal Code

522001

Country

India

Facility Name

Novartis Investigative Site

City

Vishakhapatnam

State/Province

Andhra Pradesh

ZIP/Postal Code

532 002

Country

India

Facility Name

Novartis Investigative Site

City

New Delhi

State/Province

Delhi

ZIP/Postal Code

110 060

Country

India

Facility Name

Novartis Investigative Site

City

Ahmedabad

State/Province

Gujarat

ZIP/Postal Code

380054

Country

India

Facility Name

Novartis Investigative Site

City

Surat

State/Province

Gujarat

ZIP/Postal Code

395 002

Country

India

Facility Name

Novartis Investigative Site

City

Chandigarh

State/Province

Haryana

ZIP/Postal Code

160 030

Country

India

Facility Name

Novartis Investigative Site

City

Gurgaon

State/Province

Haryana

ZIP/Postal Code

122001

Country

India

Facility Name

Novartis Investigative Site

City

Kochi

State/Province

Kerala

ZIP/Postal Code

683 594

Country

India

Facility Name

Novartis Investigative Site

City

Pune

State/Province

Maharashtra

ZIP/Postal Code

411 030

Country

India

Facility Name

Novartis Investigative Site

City

Ludhiana

State/Province

Punjab

ZIP/Postal Code

141002

Country

India

Facility Name

Novartis Investigative Site

City

Bikaner

State/Province

Rajasthan

ZIP/Postal Code

334003

Country

India

Facility Name

Novartis Investigative Site

City

Chennai

State/Province

Tamil NADU

ZIP/Postal Code

600037

Country

India

Facility Name

Novartis Investigative Site

City

Chennai

State/Province

Tamil Nadu

ZIP/Postal Code

600081

Country

India

Facility Name

Novartis Investigative Site

City

Madurai

State/Province

Tamil NADU

ZIP/Postal Code

625107

Country

India

Facility Name

Novartis Investigative Site

City

Kolkata

State/Province

West Bengal

ZIP/Postal Code

700 020

Country

India

Facility Name

Novartis Investigative Site

City

New Delhi

ZIP/Postal Code

110025

Country

India

Facility Name

Novartis Investigative Site

City

Hadera

ZIP/Postal Code

38100

Country

Israel

Facility Name

Novartis Investigative Site

City

Hadera

Country

Israel

Facility Name

Novartis Investigative Site

City

Haifa

ZIP/Postal Code

3339419

Country

Israel

Facility Name

Novartis Investigative Site

City

Haifa

ZIP/Postal Code

3525408

Country

Israel

Facility Name

Novartis Investigative Site

City

Lower Galilee

ZIP/Postal Code

15208

Country

Israel

Facility Name

Novartis Investigative Site

City

Nahariya

ZIP/Postal Code

22100

Country

Israel

Facility Name

Novartis Investigative Site

City

Petach Tikva

ZIP/Postal Code

49100

Country

Israel

Facility Name

Novartis Investigative Site

City

Ramat Gan

ZIP/Postal Code

52621

Country

Israel

Facility Name

Novartis Investigative Site

City

Rehovot

ZIP/Postal Code

76100

Country

Israel

Facility Name

Novartis Investigative Site

City

Tel Giborim, Holon

ZIP/Postal Code

58100

Country

Israel

Facility Name

Novartis Investigative Site

City

Aosta

State/Province

ZIP/Postal Code

11100

Country

Italy

Facility Name

Novartis Investigative Site

City

Cortona

State/Province

ZIP/Postal Code

52044

Country

Italy

Facility Name

Novartis Investigative Site

City

Bergamo

State/Province

ZIP/Postal Code

24127

Country

Italy

Facility Name

Novartis Investigative Site

City

Treviglio

State/Province

ZIP/Postal Code

24047

Country

Italy

Facility Name

Novartis Investigative Site

City

Bologna

State/Province

ZIP/Postal Code

40138

Country

Italy

Facility Name

Novartis Investigative Site

City

Brescia

State/Province

ZIP/Postal Code

25123

Country

Italy

Facility Name

Novartis Investigative Site

City

Cona

State/Province

ZIP/Postal Code

44100

Country

Italy

Facility Name

Novartis Investigative Site

City

Pozzilli

State/Province

ZIP/Postal Code

86077

Country

Italy

Facility Name

Novartis Investigative Site

City

Monza

State/Province

ZIP/Postal Code

20900

Country

Italy

Facility Name

Novartis Investigative Site

City

Messina

State/Province

ZIP/Postal Code

98125

Country

Italy

Facility Name

Novartis Investigative Site

City

Milano

State/Province

ZIP/Postal Code

20162

Country

Italy

Facility Name

Novartis Investigative Site

City

Vimercate

State/Province

ZIP/Postal Code

200059

Country

Italy

Facility Name

Novartis Investigative Site

City

Padova

State/Province

ZIP/Postal Code

35128

Country

Italy

Facility Name

Novartis Investigative Site

City

Perugia

State/Province

ZIP/Postal Code

06100

Country

Italy

Facility Name

Novartis Investigative Site

City

Perugia

State/Province

ZIP/Postal Code

06129

Country

Italy

Facility Name

Novartis Investigative Site

City

Pavia

State/Province

ZIP/Postal Code

27100

Country

Italy

Facility Name

Novartis Investigative Site

City

Ariccia

State/Province

ZIP/Postal Code

00041

Country

Italy

Facility Name

Novartis Investigative Site

City

Roma

State/Province

ZIP/Postal Code

00163

Country

Italy

Facility Name

Novartis Investigative Site

City

Roma

State/Province

ZIP/Postal Code

00189

Country

Italy

Facility Name

Novartis Investigative Site

City

Sassari

State/Province

ZIP/Postal Code

07100

Country

Italy

Facility Name

Novartis Investigative Site

City

Trieste

State/Province

ZIP/Postal Code

34142

Country

Italy

Facility Name

Novartis Investigative Site

City

Trieste

State/Province

ZIP/Postal Code

34149

Country

Italy

Facility Name

Novartis Investigative Site

City

Palmanova

State/Province

ZIP/Postal Code

33057

Country

Italy

Facility Name

Novartis Investigative Site

City

San Daniele Del Friuli

State/Province

ZIP/Postal Code

33038

Country

Italy

Facility Name

Novartis Investigative Site

City

Saronno

State/Province

ZIP/Postal Code

21047

Country

Italy

Facility Name

Novartis Investigative Site

City

Venezia

State/Province

ZIP/Postal Code

30174

Country

Italy

Facility Name

Novartis Investigative Site

City

Milano

ZIP/Postal Code

20149

Country

Italy

Facility Name

Novartis Investigative Site

City

Napoli

ZIP/Postal Code

80131

Country

Italy

Facility Name

Novartis Investigative Site

City

Seto-city

State/Province

Aichi

ZIP/Postal Code

489-8642

Country

Japan

Facility Name

Novartis Investigative Site

City

Chikushino-city

State/Province

Fukuka

ZIP/Postal Code

818-8516

Country

Japan

Facility Name

Novartis Investigative Site

City

Ogaki-city

State/Province

Gifu

ZIP/Postal Code

503-8502

Country

Japan

Facility Name

Novartis Investigative Site

City

Maebashi city

State/Province

Gunma

ZIP/Postal Code

371 8511

Country

Japan

Facility Name

Novartis Investigative Site

City

Amagasaki city

State/Province

Hyogo

ZIP/Postal Code

660 8550

Country

Japan

Facility Name

Novartis Investigative Site

City

Kanazawa

State/Province

Ishikawa

ZIP/Postal Code

920 8650

Country

Japan

Facility Name

Novartis Investigative Site

City

Morioka

State/Province

Iwate

ZIP/Postal Code

020 0066

Country

Japan

Facility Name

Novartis Investigative Site

City

Kanonji-city

State/Province

Kagawa

ZIP/Postal Code

769-1695

Country

Japan

Facility Name

Novartis Investigative Site

City

Takamatsu city

State/Province

Kagawa

ZIP/Postal Code

760 8557

Country

Japan

Facility Name

Novartis Investigative Site

City

Yokohama-city

State/Province

Kanagawa

ZIP/Postal Code

227-8501

Country

Japan

Facility Name

Novartis Investigative Site

City

Yokohama-city

State/Province

Kanagawa

ZIP/Postal Code

236 0051

Country

Japan

Facility Name

Novartis Investigative Site

City

Sendai city

State/Province

Miyagi

ZIP/Postal Code

980 8574

Country

Japan

Facility Name

Novartis Investigative Site

City

Kashihara city

State/Province

Nara

ZIP/Postal Code

634 8522

Country

Japan

Facility Name

Novartis Investigative Site

City

Sayama-city

State/Province

Saitama

ZIP/Postal Code

350-1305

Country

Japan

Facility Name

Novartis Investigative Site

City

Kusatsu city

State/Province

Shiga

ZIP/Postal Code

525 8585

Country

Japan

Facility Name

Novartis Investigative Site

City

Chiyoda-ku

State/Province

Tokyo

ZIP/Postal Code

101-8309

Country

Japan

Facility Name

Novartis Investigative Site

City

Hachioji-city

State/Province

Tokyo

ZIP/Postal Code

192-0918

Country

Japan

Facility Name

Novartis Investigative Site

City

Itabashi-ku

State/Province

Tokyo

ZIP/Postal Code

173-8610

Country

Japan

Facility Name

Novartis Investigative Site

City

Shinagawa-ku

State/Province

Tokyo

ZIP/Postal Code

142-8666

Country

Japan

Facility Name

Novartis Investigative Site

City

Gyeonggi do

State/Province

Bucheon Si

ZIP/Postal Code

422-711

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Cheongju si

State/Province

Chungcheongbuk Do

ZIP/Postal Code

28644

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Wonju

State/Province

Gangwon-do

ZIP/Postal Code

26427

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Bundang Gu

State/Province

Gyeonggi Do

ZIP/Postal Code

13620

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

State/Province

Korea

ZIP/Postal Code

05505

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Incheon

State/Province

KOR

ZIP/Postal Code

22332

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

State/Province

KOR

ZIP/Postal Code

08308

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Daegu

ZIP/Postal Code

705 718

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

ZIP/Postal Code

02841

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

ZIP/Postal Code

03080

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

ZIP/Postal Code

03722

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Seoul

ZIP/Postal Code

06351

Country

Korea, Republic of

Facility Name

Novartis Investigative Site

City

Torreon

State/Province

Coahulia

ZIP/Postal Code

27000

Country

Mexico

Facility Name

Novartis Investigative Site

City

Mexico

State/Province

Distrito Federal

ZIP/Postal Code

14080

Country

Mexico

Facility Name

Novartis Investigative Site

City

Leon

State/Province

Guanajuato

ZIP/Postal Code

37530

Country

Mexico

Facility Name

Novartis Investigative Site

City

Zapopan

State/Province

Jalisco

ZIP/Postal Code

45200

Country

Mexico

Facility Name

Novartis Investigative Site

City

San Juan del Rio

State/Province

Queretaro

ZIP/Postal Code

76800

Country

Mexico

Facility Name

Novartis Investigative Site

City

San Luis Potosi

State/Province

San Luis Potosí

ZIP/Postal Code

78240

Country

Mexico

Facility Name

Novartis Investigative Site

City

Culiacan

State/Province

Sinaloa

ZIP/Postal Code

80230

Country

Mexico

Facility Name

Novartis Investigative Site

City

Aguascalientes

ZIP/Postal Code

20230

Country

Mexico

Facility Name

Novartis Investigative Site

City

Queretaro

ZIP/Postal Code

76000

Country

Mexico

Facility Name

Novartis Investigative Site

City

San Luis Potosi

ZIP/Postal Code

78200

Country

Mexico

Facility Name

Novartis Investigative Site

City

San Luis Potosí

ZIP/Postal Code

78200

Country

Mexico

Facility Name

Novartis Investigative Site

City

Apeldoorn

State/Province

ZIP/Postal Code

7334

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Den Haag

State/Province

ZIP/Postal Code

2597 AX

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Almelo

State/Province

ZIP/Postal Code

7609

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Arnhem

ZIP/Postal Code

6815 AD

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Blaricum

ZIP/Postal Code

1261 AN

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Den Haag

ZIP/Postal Code

2512 VA

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Ede

ZIP/Postal Code

6716 RP

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Gouda

ZIP/Postal Code

2803 HH

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Groningen

ZIP/Postal Code

9713 GZ

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Hardenberg

ZIP/Postal Code

7770 AA

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Harderwijk

ZIP/Postal Code

3840 AC

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Nijmegen

ZIP/Postal Code

6500 HB

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Rotterdam

ZIP/Postal Code

3015 CE

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Sneek

ZIP/Postal Code

8601 ZK

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Tilburg

ZIP/Postal Code

5022 GC

Country

Netherlands

Facility Name

Novartis Investigative Site

City

Loerenskog

ZIP/Postal Code

NO 1478

Country

Norway

Facility Name

Novartis Investigative Site

City

Oslo

ZIP/Postal Code

0450

Country

Norway

Facility Name

Novartis Investigative Site

City

Stavanger

ZIP/Postal Code

4068

Country

Norway

Facility Name

Novartis Investigative Site

City

Tromsoe

ZIP/Postal Code

NO-9038

Country

Norway

Facility Name

Novartis Investigative Site

City

Bellavista

State/Province

Lima

ZIP/Postal Code

CALLAO 02

Country

Peru

Facility Name

Novartis Investigative Site

City

Cercado De Lima

State/Province

Lima

ZIP/Postal Code

Country

Peru

Facility Name

Novartis Investigative Site

City

Jesus Maria

State/Province

Lima

ZIP/Postal Code

Country

Peru

Facility Name

Novartis Investigative Site

City

Miraflores

State/Province

Lima

ZIP/Postal Code

Country

Peru

Facility Name

Novartis Investigative Site

City

San Isidro

State/Province

Lima

ZIP/Postal Code

Country

Peru

Facility Name

Novartis Investigative Site

City

Lipa City

State/Province

Batangas

ZIP/Postal Code

4217

Country

Philippines

Facility Name

Novartis Investigative Site

City

Quezon City

State/Province

Manila

ZIP/Postal Code

1100

Country

Philippines

Facility Name

Novartis Investigative Site

City

Quezon City

ZIP/Postal Code

1100

Country

Philippines

Facility Name

Novartis Investigative Site

City

Quezon City

ZIP/Postal Code

1102

Country

Philippines

Facility Name

Novartis Investigative Site

City

Lodz

State/Province

Lodzkie

ZIP/Postal Code

90 549

Country

Poland

Facility Name

Novartis Investigative Site

City

Gdynia

ZIP/Postal Code

81-157

Country

Poland

Facility Name

Novartis Investigative Site

City

Gdynia

ZIP/Postal Code

81-548

Country

Poland

Facility Name

Novartis Investigative Site

City

Grodzisk Mazowiecki

ZIP/Postal Code

05 825

Country

Poland

Facility Name

Novartis Investigative Site

City

Katowice

ZIP/Postal Code

40-645

Country

Poland

Facility Name

Novartis Investigative Site

City

Krakow

ZIP/Postal Code

30-015

Country

Poland

Facility Name

Novartis Investigative Site

City

Krakow

ZIP/Postal Code

31 501

Country

Poland

Facility Name

Novartis Investigative Site

City

Lublin

ZIP/Postal Code

20-363

Country

Poland

Facility Name

Novartis Investigative Site

City

Sandomierz

ZIP/Postal Code

27 600

Country

Poland

Facility Name

Novartis Investigative Site

City

Staszów

ZIP/Postal Code

28-200

Country

Poland

Facility Name

Novartis Investigative Site

City

Torun

ZIP/Postal Code

87-100

Country

Poland

Facility Name

Novartis Investigative Site

City

Warszawa/Anin

ZIP/Postal Code

04-761

Country

Poland

Facility Name

Novartis Investigative Site

City

Warszawa

ZIP/Postal Code

02-097

Country

Poland

Facility Name

Novartis Investigative Site

City

Warszawa

ZIP/Postal Code

04-154

Country

Poland

Facility Name

Novartis Investigative Site

City

Zabrze

ZIP/Postal Code

41 800

Country

Poland

Facility Name

Novartis Investigative Site

City

Zamosc

ZIP/Postal Code

22-400

Country

Poland

Facility Name

Novartis Investigative Site

City

Pitesti

State/Province

Arges

ZIP/Postal Code

110438

Country

Romania

Facility Name

Novartis Investigative Site

City

Bucuresti

State/Province

District 1

ZIP/Postal Code

014461

Country

Romania

Facility Name

Novartis Investigative Site

City

Craiova

State/Province

Jud. Dolj

ZIP/Postal Code

200497

Country

Romania

Facility Name

Novartis Investigative Site

City

Sibiu

State/Province

Jud. Iasi

ZIP/Postal Code

550371

Country

Romania

Facility Name

Novartis Investigative Site

City

Timisoara

State/Province

Timis

ZIP/Postal Code

300125

Country

Romania

Facility Name

Novartis Investigative Site

City

Timisoara

State/Province

Timis

ZIP/Postal Code

300362

Country

Romania

Facility Name

Novartis Investigative Site

City

Arad

ZIP/Postal Code

310158

Country

Romania

Facility Name

Novartis Investigative Site

City

Baia Mare

ZIP/Postal Code

430222

Country

Romania

Facility Name

Novartis Investigative Site

City

Bucharest

ZIP/Postal Code

050098

Country

Romania

Facility Name

Novartis Investigative Site

City

Bucuresti

ZIP/Postal Code

062272

Country

Romania

Facility Name

Novartis Investigative Site

City

Targu Mures

ZIP/Postal Code

540142

Country

Romania

Facility Name

Novartis Investigative Site

City

Targu Mures

ZIP/Postal Code

540143

Country

Romania

Facility Name

Novartis Investigative Site

City

Timisoara

ZIP/Postal Code

300041

Country

Romania

Facility Name

Novartis Investigative Site

City

Ekaterinburg

ZIP/Postal Code

620028

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Ekaterinburg

ZIP/Postal Code

620137

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Ivanovo

ZIP/Postal Code

153012

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Izhevsk

ZIP/Postal Code

426009

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Izhevsk

ZIP/Postal Code

426063

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Kemerovo

ZIP/Postal Code

650029

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Kemerovo

ZIP/Postal Code

650099

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Kirov

ZIP/Postal Code

610027

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Kirov

ZIP/Postal Code

610035

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

101990

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

117198

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

121309

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Moscow

ZIP/Postal Code

121552

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

N.Novgorod

ZIP/Postal Code

603005

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Perm

ZIP/Postal Code

614990

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Rostov on Don

ZIP/Postal Code

344022

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Rostov-on-Don

ZIP/Postal Code

344068

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Saint Petersburg

ZIP/Postal Code

194044

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Saint Petersburg

ZIP/Postal Code

197022

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Saint Petersburg

ZIP/Postal Code

197341

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Saint Petersburg

ZIP/Postal Code

199106

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Saint-Petersburg

ZIP/Postal Code

192257

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Saratov

ZIP/Postal Code

410012

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Sestroretsk

ZIP/Postal Code

197706

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Smolensk

ZIP/Postal Code

214018

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

St Petersburg

ZIP/Postal Code

196601

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

St-Petersburg

ZIP/Postal Code

194295

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

St.- Petersburg

ZIP/Postal Code

197110

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Yaroslavl

ZIP/Postal Code

150003

Country

Russian Federation

Facility Name

Novartis Investigative Site

City

Belgrade

ZIP/Postal Code

11000

Country

Serbia

Facility Name

Novartis Investigative Site

City

Beograd

ZIP/Postal Code

11040

Country

Serbia

Facility Name

Novartis Investigative Site

City

Niska Banja

ZIP/Postal Code

18205

Country

Serbia

Facility Name

Novartis Investigative Site

City

Nis

ZIP/Postal Code

18000

Country

Serbia

Facility Name

Novartis Investigative Site

City

Singapore

ZIP/Postal Code

119074

Country

Singapore

Facility Name

Novartis Investigative Site

City

Singapore

ZIP/Postal Code

169609

Country

Singapore

Facility Name

Novartis Investigative Site

City

Singapore

ZIP/Postal Code

308433

Country

Singapore

Facility Name

Novartis Investigative Site

City

Singapore

ZIP/Postal Code

529889

Country

Singapore

Facility Name

Novartis Investigative Site

City

Singapore

ZIP/Postal Code

768828

Country

Singapore

Facility Name

Novartis Investigative Site

City

Brezno

State/Province

Slovak Republic

ZIP/Postal Code

977 42

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Komarno

State/Province

Slovak Republic

ZIP/Postal Code

94501

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Levice

State/Province

Slovak Republic

ZIP/Postal Code

93401

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Namestovo

State/Province

Slovak Republic

ZIP/Postal Code

02901

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Povazska Bystrica

State/Province

Slovak Republic

ZIP/Postal Code

01701

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Presov

State/Province

Slovak Republic

ZIP/Postal Code

08001

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Bardejov

ZIP/Postal Code

085 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Bratislava

ZIP/Postal Code

821 07

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Bratislava

ZIP/Postal Code

831 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Bratislava

ZIP/Postal Code

833 48

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Bratislava

ZIP/Postal Code

841 07

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Bratislava

ZIP/Postal Code

842 31

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Bratislava

ZIP/Postal Code

851 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Kosice

ZIP/Postal Code

040 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Levice

ZIP/Postal Code

934 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Lucenec

ZIP/Postal Code

984 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Lucenec

ZIP/Postal Code

98439

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Nitra

ZIP/Postal Code

949 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Nitra

ZIP/Postal Code

949 88

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Nove Zamky

ZIP/Postal Code

940 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Nove Zamky

ZIP/Postal Code

94002

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Piestany

ZIP/Postal Code

921 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Presov

ZIP/Postal Code

080 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Svidnik

ZIP/Postal Code

089 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Trebisov

ZIP/Postal Code

075 01

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Zilina

ZIP/Postal Code

012 07

Country

Slovakia

Facility Name

Novartis Investigative Site

City

Golnik

ZIP/Postal Code

4204

Country

Slovenia

Facility Name

Novartis Investigative Site

City

Ljubljana

ZIP/Postal Code

1000

Country

Slovenia

Facility Name

Novartis Investigative Site

City

Bloemfontein

State/Province

Free State

ZIP/Postal Code

9301

Country

South Africa

Facility Name

Novartis Investigative Site

City

Soweto

State/Province

Gauteng

ZIP/Postal Code

2013

Country

South Africa

Facility Name

Novartis Investigative Site

City

Durban

State/Province

Kwa-Zulu Natal

ZIP/Postal Code

4052

Country

South Africa

Facility Name

Novartis Investigative Site

City

Alberton

ZIP/Postal Code

1449

Country

South Africa

Facility Name

Novartis Investigative Site

City

Bloemfontein

ZIP/Postal Code

9301

Country

South Africa

Facility Name

Novartis Investigative Site

City

Cape Town

ZIP/Postal Code

7500

Country

South Africa

Facility Name

Novartis Investigative Site

City

Cape Town

ZIP/Postal Code

7531

Country

South Africa

Facility Name

Novartis Investigative Site

City

Cape Town

ZIP/Postal Code

7925

Country

South Africa

Facility Name

Novartis Investigative Site

City

Durban

ZIP/Postal Code

4001

Country

South Africa

Facility Name

Novartis Investigative Site

City

Tongaat

ZIP/Postal Code

3300

Country

South Africa

Facility Name

Novartis Investigative Site

City

Western Cape

ZIP/Postal Code

7130

Country

South Africa

Facility Name

Novartis Investigative Site

City

Worcester

ZIP/Postal Code

6850

Country

South Africa

Facility Name

Novartis Investigative Site

City

Almeria

State/Province

Andalucia

ZIP/Postal Code

04120

Country

Spain

Facility Name

Novartis Investigative Site

City

Cordoba

State/Province

Andalucia

ZIP/Postal Code

14004

Country

Spain

Facility Name

Novartis Investigative Site

City

Malaga

State/Province

Andalucia

ZIP/Postal Code

29010

Country

Spain

Facility Name

Novartis Investigative Site

City

Marbella

State/Province

Andalucia

ZIP/Postal Code

29600

Country

Spain

Facility Name

Novartis Investigative Site

City

Sanlúcar de Barrameda

State/Province

Andalucia

ZIP/Postal Code

11540

Country

Spain

Facility Name

Novartis Investigative Site

City

Sevilla

State/Province

Andalucia

ZIP/Postal Code

41013

Country

Spain

Facility Name

Novartis Investigative Site

City

Sevilla

State/Province

Andalucia

ZIP/Postal Code

41014

Country

Spain

Facility Name

Novartis Investigative Site

City

Sant Joan Despi

State/Province

Barcelona

ZIP/Postal Code

08970

Country

Spain

Facility Name

Novartis Investigative Site

City

Villamartin

State/Province

Cadiz

ZIP/Postal Code

11650

Country

Spain

Facility Name

Novartis Investigative Site

City

Santander

State/Province

Cantabria

ZIP/Postal Code

39008

Country

Spain

Facility Name

Novartis Investigative Site

City

Aranda de Duero

State/Province

Castilla Y Leon

ZIP/Postal Code

09400

Country

Spain

Facility Name

Novartis Investigative Site

City

Leon

State/Province

Castilla Y Leon

ZIP/Postal Code

24071

Country

Spain

Facility Name

Novartis Investigative Site

City

Lerida

State/Province

Cataluna

ZIP/Postal Code

25198

Country

Spain

Facility Name

Novartis Investigative Site

City

Badalona

State/Province

Catalunya

ZIP/Postal Code

08916

Country

Spain

Facility Name

Novartis Investigative Site

City

Barcelona

State/Province

Catalunya

ZIP/Postal Code

08003

Country

Spain

Facility Name

Novartis Investigative Site

City

Alzira

State/Province

Comunidad Valenciana

ZIP/Postal Code

46600

Country

Spain

Facility Name

Novartis Investigative Site

City

Valencia

State/Province

Comunidad Valenciana

ZIP/Postal Code

46010

Country

Spain

Facility Name

Novartis Investigative Site

City

Valencia

State/Province

Comunidad Valenciana

ZIP/Postal Code

46014

Country

Spain

Facility Name

Novartis Investigative Site

City

Valencia

State/Province

Comunidad Valenciana

ZIP/Postal Code

46026

Country

Spain

Facility Name

Novartis Investigative Site

City

Merida

State/Province

Extremadura

ZIP/Postal Code

06800

Country

Spain

Facility Name

Novartis Investigative Site

City

A Coruna

State/Province

Galicia

ZIP/Postal Code

15006

Country

Spain

Facility Name

Novartis Investigative Site

City

Santiago de Compostela

State/Province

Galicia

ZIP/Postal Code

15706

Country

Spain

Facility Name

Novartis Investigative Site

City

Olot

State/Province

Girona

ZIP/Postal Code

17800

Country

Spain

Facility Name

Novartis Investigative Site

City

Mostoles

State/Province

Madrid

ZIP/Postal Code

28935

Country

Spain

Facility Name

Novartis Investigative Site

City

El Palmar

State/Province

Murcia

ZIP/Postal Code

30120

Country

Spain

Facility Name

Novartis Investigative Site

City

Ciudad Real

ZIP/Postal Code

13005

Country

Spain

Facility Name

Novartis Investigative Site

City

Madrid

ZIP/Postal Code

28009

Country

Spain

Facility Name

Novartis Investigative Site

City

Madrid

ZIP/Postal Code

28034

Country

Spain

Facility Name

Novartis Investigative Site

City

Madrid

ZIP/Postal Code

28040

Country

Spain

Facility Name

Novartis Investigative Site

City

Madrid

ZIP/Postal Code

28046

Country

Spain

Facility Name

Novartis Investigative Site

City

Madrid

ZIP/Postal Code

28222

Country

Spain

Facility Name

Novartis Investigative Site

City

Danderyd

ZIP/Postal Code

182 88

Country

Sweden

Facility Name

Novartis Investigative Site

City

Falun

ZIP/Postal Code

791 82

Country

Sweden

Facility Name

Novartis Investigative Site

City

Goteborg

ZIP/Postal Code

413 45

Country

Sweden

Facility Name

Novartis Investigative Site

City

Karlstad

ZIP/Postal Code

652 30

Country

Sweden

Facility Name

Novartis Investigative Site

City

Lund

ZIP/Postal Code

222 21

Country

Sweden

Facility Name

Novartis Investigative Site

City

Orebro

ZIP/Postal Code

701 85

Country

Sweden

Facility Name

Novartis Investigative Site

City

Stockholm

ZIP/Postal Code

17176

Country

Sweden

Facility Name

Novartis Investigative Site

City

Vasteras

ZIP/Postal Code

72189

Country

Sweden

Facility Name

Novartis Investigative Site

City

Basel

ZIP/Postal Code

4031

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Bern

ZIP/Postal Code

3010

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Biel

ZIP/Postal Code

2502

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Lausanne

ZIP/Postal Code

1011

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Zurich

ZIP/Postal Code

8091

Country

Switzerland

Facility Name

Novartis Investigative Site

City

Tainan

State/Province

Taiwan ROC

ZIP/Postal Code

70403

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Changhua

ZIP/Postal Code

50006

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Kaohsiung

ZIP/Postal Code

80756

Country

Taiwan

Facility Name

Novartis Investigative Site

City

New Taipei

ZIP/Postal Code

22060

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Taichung

ZIP/Postal Code

40447

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Tainan

ZIP/Postal Code

71004

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Taipei

ZIP/Postal Code

10002

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Taipei

ZIP/Postal Code

11217

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Yilan

ZIP/Postal Code

26058

Country

Taiwan

Facility Name

Novartis Investigative Site

City

Istanbul

State/Province

TUR

ZIP/Postal Code

34098

Country

Turkey

Facility Name

Novartis Investigative Site

City

Haydarpasa Istanbul

ZIP/Postal Code

34668

Country

Turkey

Facility Name

Novartis Investigative Site

City

Istanbul

ZIP/Postal Code

34304

Country

Turkey

Facility Name

Novartis Investigative Site

City

Izmir

ZIP/Postal Code

35040

Country

Turkey

Facility Name

Novartis Investigative Site

City

Izmir

ZIP/Postal Code

35340

Country

Turkey

Facility Name

Novartis Investigative Site

City

Kocaeli

ZIP/Postal Code

41380

Country

Turkey

Facility Name

Novartis Investigative Site

City

Pendik / Istanbul

ZIP/Postal Code

34899

Country

Turkey

Facility Name

Novartis Investigative Site

City

Sivas

ZIP/Postal Code

58140

Country

Turkey

Facility Name

Novartis Investigative Site

City

High Wycombe

State/Province

Buckinghamshire

ZIP/Postal Code

HP11 2TT

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Stockton on Tees

State/Province

Cleveland

ZIP/Postal Code

TS19 8PE

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Darlington

State/Province

Co Durham

ZIP/Postal Code

DL3 8SQ

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Durham

State/Province

County Durham

ZIP/Postal Code

DH1 5TW

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Torquay

State/Province

Devon

ZIP/Postal Code

TQ2 7AA

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Dorchester

State/Province

Dorset

ZIP/Postal Code

DT1 2JY

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Peterborough

State/Province

GBR

ZIP/Postal Code

PE3 6DA

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Basingstoke

State/Province

Hampshire

ZIP/Postal Code

RG24 9NA

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Portsmouth

State/Province

Hampshire

ZIP/Postal Code

PO6 3LY

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Oldham

State/Province

Lancashire

ZIP/Postal Code

OL1 2JH

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Harrow

State/Province

Middlesex

ZIP/Postal Code

HA1 3UJ

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Portadown

State/Province

Nothern Ireland

ZIP/Postal Code

BT63 5QQ

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Wansford

State/Province

Peterborough

ZIP/Postal Code

PE8 6PL

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Glasgow

State/Province

Scotland

ZIP/Postal Code

G12 8TA

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Taunton

State/Province

Somerset

ZIP/Postal Code

TA1 5DA

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Gateshead

State/Province

Tyne And Wear

ZIP/Postal Code

NE9 6SX

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Clydebank

State/Province

West Dumbartonshire

ZIP/Postal Code

G81 4HX

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Cheshire

ZIP/Postal Code

CW1 4QJ

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Coventry

ZIP/Postal Code

CV2 2DX

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Dundee

ZIP/Postal Code

DD1 9SY

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Glasgow

ZIP/Postal Code

G20 0XA

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Hull

ZIP/Postal Code

HU16 5JQ

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

London

ZIP/Postal Code

SE5 9RS

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

London

ZIP/Postal Code

SW 6NP

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Newport

ZIP/Postal Code

NP20 2UB

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Nottingham

ZIP/Postal Code

NG5 1PB

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Sheffield

ZIP/Postal Code

S5 7AU

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Swindon

ZIP/Postal Code

SN3 6BB

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Wiltshire

ZIP/Postal Code

SN15 2SB

Country

United Kingdom

Facility Name

Novartis Investigative Site

City

Wrexham

ZIP/Postal Code

LL13 7TD

Country

United Kingdom

12. IPD Sharing Statement

Plan to Share IPD

Yes

IPD Sharing Plan Description

Novartis is committed to sharing with qualified external researchers, access to patient-level data and supporting clinical documents from eligible studies. These requests are reviewed and approved by an independent review panel on the basis of scientific merit. All data provided is anonymized to respect the privacy of patients who have participated in the trial in line with applicable laws and regulations. This trial data availability is according to the criteria and process described on www.clinicalstudydatarequest.com.

Citations:

PubMed Identifier

36050227

Citation

Butt JH, Dewan P, Jhund PS, Anand IS, Atar D, Ge J, Desai AS, Echeverria LE, Kober L, Lam CSP, Maggioni AP, Martinez F, Packer M, Rouleau JL, Sim D, Van Veldhuisen DJ, Vrtovec B, Zannad F, Zile MR, Gong J, Lefkowitz MP, Rizkala AR, Solomon SD, McMurray JJV. Sacubitril/Valsartan and Frailty in Patients With Heart Failure and Preserved Ejection Fraction. J Am Coll Cardiol. 2022 Sep 20;80(12):1130-1143. doi: 10.1016/j.jacc.2022.06.037. Epub 2022 Aug 29.

Results Reference

derived

PubMed Identifier

35717169

Citation

Wijkman MO, Claggett B, Vaduganathan M, Cunningham JW, Rorth R, Jackson A, Packer M, Zile M, Rouleau J, Swedberg K, Lefkowitz M, Shah SJ, Pfeffer MA, McMurray JJV, Solomon SD. Effects of sacubitril/valsartan on glycemia in patients with diabetes and heart failure: the PARAGON-HF and PARADIGM-HF trials. Cardiovasc Diabetol. 2022 Jun 18;21(1):110. doi: 10.1186/s12933-022-01545-1.

Results Reference

derived

PubMed Identifier

35603667

Citation

Vaduganathan M, Claggett BL, Inciardi RM, Fonarow GC, McMurray JJV, Solomon SD. Estimating the Benefits of Combination Medical Therapy in Heart Failure With Mildly Reduced and Preserved Ejection Fraction. Circulation. 2022 Jun 7;145(23):1741-1743. doi: 10.1161/CIRCULATIONAHA.121.058929. Epub 2022 May 23. No abstract available.

Results Reference

derived

PubMed Identifier

35603665

Citation

Vaduganathan M, Claggett BL, McMurray JJV, Solomon SD. Health Status Trajectories Before and After Hospitalization for Heart Failure. Circulation. 2022 Jun 21;145(25):1872-1874. doi: 10.1161/CIRCULATIONAHA.122.059282. Epub 2022 May 21. No abstract available.

Results Reference

derived

PubMed Identifier

35483796

Citation

Cikes M, Planinc I, Claggett B, Cunningham J, Milicic D, Sweitzer N, Senni M, Gori M, Linssen G, Shah SJ, Packer M, Pfeffer M, Zile MR, Anand I, Chiang LM, Lam CSP, Redfield M, Desai AS, McMurray JJV, Solomon SD. Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Trial. JACC Heart Fail. 2022 May;10(5):336-346. doi: 10.1016/j.jchf.2022.01.018. Epub 2022 Apr 6.

Results Reference

derived

PubMed Identifier

34918855

Citation

Jackson AM, Rorth R, Liu J, Kristensen SL, Anand IS, Claggett BL, Cleland JGF, Chopra VK, Desai AS, Ge J, Gong J, Lam CSP, Lefkowitz MP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rizkala AR, Rouleau JL, Seferovic PM, Tromp J, Van Veldhuisen DJ, Yilmaz MB, Zannad F, Zile MR, Kober L, Petrie MC, Jhund PS, Solomon SD, McMurray JJV; PARAGON-HF Committees and Investigators. Diabetes and pre-diabetes in patients with heart failure and preserved ejection fraction. Eur J Heart Fail. 2022 Mar;24(3):497-509. doi: 10.1002/ejhf.2403. Epub 2022 Jan 4.

Results Reference

derived

PubMed Identifier

34807713

Citation

Desai AS, Vaduganathan M, Cleland JG, Claggett BL, Barkoudah E, Finn P, McCausland FR, Yilmaz MB, Lefkowitz M, Shi V, Pfeffer MA, McMurray JJV, Solomon SD. Mode of Death in Patients With Heart Failure and Preserved Ejection Fraction: Insights From PARAGON-HF Trial. Circ Heart Fail. 2021 Dec;14(12):e008597. doi: 10.1161/CIRCHEARTFAILURE.121.008597. Epub 2021 Nov 22.

Results Reference

derived

PubMed Identifier

34796742

Citation

Mooney L, Hawkins NM, Jhund PS, Redfield MM, Vaduganathan M, Desai AS, Rouleau JL, Minamisawa M, Shah AM, Lefkowitz MP, Zile MR, Van Veldhuisen DJ, Pfeffer MA, Anand IS, Maggioni AP, Senni M, Claggett BL, Solomon SD, McMurray JJV. Impact of Chronic Obstructive Pulmonary Disease in Patients With Heart Failure With Preserved Ejection Fraction: Insights From PARAGON-HF. J Am Heart Assoc. 2021 Dec 7;10(23):e021494. doi: 10.1161/JAHA.121.021494. Epub 2021 Nov 19.

Results Reference

derived

PubMed Identifier

34392331

Citation

Jackson AM, Jhund PS, Anand IS, Dungen HD, Lam CSP, Lefkowitz MP, Linssen G, Lund LH, Maggioni AP, Pfeffer MA, Rouleau JL, Saraiva JFK, Senni M, Vardeny O, Wijkman MO, Yilmaz MB, Saito Y, Zile MR, Solomon SD, McMurray JJV. Sacubitril-valsartan as a treatment for apparent resistant hypertension in patients with heart failure and preserved ejection fraction. Eur Heart J. 2021 Sep 21;42(36):3741-3752. doi: 10.1093/eurheartj/ehab499.

Results Reference

derived

PubMed Identifier

34097449

Citation

Felker GM, Butler J, Januzzi JL Jr, Desai AS, McMurray JJV, Solomon SD. Probabilistic Readjudication of Heart Failure Hospitalization Events in the PARAGON-HF Study. Circulation. 2021 Jun 8;143(23):2316-2318. doi: 10.1161/CIRCULATIONAHA.121.054496. Epub 2021 Jun 7. No abstract available.

Results Reference

derived

PubMed Identifier

33998278

Citation

Selvaraj S, Claggett BL, Packer M, Zannad F, Anand IS, Pieske B, Zhao Z, Shi VC, Lefkowitz MP, McMurray JJV, Solomon SD. Effects of Sacubitril/Valsartan on Serum Lipids in Heart Failure With Preserved Ejection Fraction. J Am Heart Assoc. 2021 Sep 7;10(17):e022069. doi: 10.1161/JAHA.121.022069. Epub 2021 May 16.

Results Reference

derived

PubMed Identifier

33888245

Citation

Shen L, Jhund PS, Anand IS, Bhatt AS, Desai AS, Maggioni AP, Martinez FA, Pfeffer MA, Rizkala AR, Rouleau JL, Swedberg K, Vaduganathan M, Vardeny O, van Veldhuisen DJ, Zannad F, Zile MR, Packer M, Solomon SD, McMurray JJV. Incidence and Outcomes of Pneumonia in Patients With Heart Failure. J Am Coll Cardiol. 2021 Apr 27;77(16):1961-1973. doi: 10.1016/j.jacc.2021.03.001.

Results Reference

derived

PubMed Identifier

33866828

Citation

Tromp J, Claggett BL, Liu J, Jackson AM, Jhund PS, Kober L, Widimsky J, Boytsov SA, Chopra VK, Anand IS, Ge J, Chen CH, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, Van Veldhuisen DJ, Zannad F, Zile MR, Rizkala AR, Inubushi-Molessa A, Lefkowitz MP, Shi VC, McMurray JJV, Solomon SD, Lam CSP; PARAGON-HF Investigators. Global Differences in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Trial. Circ Heart Fail. 2021 Apr;14(4):e007901. doi: 10.1161/CIRCHEARTFAILURE.120.007901. Epub 2021 Apr 19.

Results Reference

derived

PubMed Identifier

33839075

Citation

Vaduganathan M, Cunningham JW, Claggett BL, Causland FM, Barkoudah E, Finn P, Zannad F, Pfeffer MA, Rizkala AR, Sabarwal S, McMurray JJV, Solomon S, Desai AS. Worsening Heart Failure Episodes Outside a Hospital Setting in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Trial. JACC Heart Fail. 2021 May;9(5):374-382. doi: 10.1016/j.jchf.2021.01.014. Epub 2021 Apr 7.

Results Reference

derived

PubMed Identifier

33727901

Citation

Gronda E, Vanoli E, Iacoviello M. The PARAGON-HF trial: the sacubitril/valsartan in heart failure with preserved ejection fraction. Eur Heart J Suppl. 2020 Nov 18;22(Suppl L):L77-L81. doi: 10.1093/eurheartj/suaa140. eCollection 2020 Nov.

Results Reference

derived

PubMed Identifier

33714741

Citation

Jering K, Claggett B, Redfield MM, Shah SJ, Anand IS, Martinez F, Sabarwal SV, Seferovic PM, Kerr Saraiva JF, Katova T, Lefkowitz MP, Pfeffer MA, McMurray JJV, Solomon SD. Burden of Heart Failure Signs and Symptoms, Prognosis, and Response to Therapy: The PARAGON-HF Trial. JACC Heart Fail. 2021 May;9(5):386-397. doi: 10.1016/j.jchf.2021.01.011. Epub 2021 Mar 10.

Results Reference

derived

PubMed Identifier

33189633

Citation

Jering KS, Zannad F, Claggett B, Mc Causland FR, Ferreira JP, Desai A, Barkoudah E, McMurray JJV, Pfeffer MA, Solomon SD. Cardiovascular and Renal Outcomes of Mineralocorticoid Receptor Antagonist Use in PARAGON-HF. JACC Heart Fail. 2021 Jan;9(1):13-24. doi: 10.1016/j.jchf.2020.08.014. Epub 2020 Nov 11.

Results Reference

derived

PubMed Identifier

32845715

Citation

Mc Causland FR, Lefkowitz MP, Claggett B, Anavekar NS, Senni M, Gori M, Jhund PS, McGrath MM, Packer M, Shi V, Van Veldhuisen DJ, Zannad F, Comin-Colet J, Pfeffer MA, McMurray JJV, Solomon SD. Angiotensin-Neprilysin Inhibition and Renal Outcomes in Heart Failure With Preserved Ejection Fraction. Circulation. 2020 Sep 29;142(13):1236-1245. doi: 10.1161/CIRCULATIONAHA.120.047643. Epub 2020 Aug 17.

Results Reference

derived

PubMed Identifier

32731928

Citation

Cunningham JW, Claggett BL, O'Meara E, Prescott MF, Pfeffer MA, Shah SJ, Redfield MM, Zannad F, Chiang LM, Rizkala AR, Shi VC, Lefkowitz MP, Rouleau J, McMurray JJV, Solomon SD, Zile MR. Effect of Sacubitril/Valsartan on Biomarkers of Extracellular Matrix Regulation in Patients With HFpEF. J Am Coll Cardiol. 2020 Aug 4;76(5):503-514. doi: 10.1016/j.jacc.2020.05.072.

Results Reference

derived

PubMed Identifier

32241619

Citation

Cunningham JW, Vaduganathan M, Claggett BL, Zile MR, Anand IS, Packer M, Zannad F, Lam CSP, Janssens S, Jhund PS, Kober L, Rouleau J, Shah SJ, Chopra VK, Shi VC, Lefkowitz MP, Prescott MF, Pfeffer MA, McMurray JJV, Solomon SD. Effects of Sacubitril/Valsartan on N-Terminal Pro-B-Type Natriuretic Peptide in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail. 2020 May;8(5):372-381. doi: 10.1016/j.jchf.2020.03.002. Epub 2020 Mar 30.

Results Reference

derived

PubMed Identifier

32192799

Citation

Selvaraj S, Claggett BL, Bohm M, Anker SD, Vaduganathan M, Zannad F, Pieske B, Lam CSP, Anand IS, Shi VC, Lefkowitz MP, McMurray JJV, Solomon SD. Systolic Blood Pressure in Heart Failure With Preserved Ejection Fraction Treated With Sacubitril/Valsartan. J Am Coll Cardiol. 2020 Apr 14;75(14):1644-1656. doi: 10.1016/j.jacc.2020.02.009. Epub 2020 Mar 16.

Results Reference

derived

PubMed Identifier

31806129

Citation

Shah AM, Cikes M, Prasad N, Li G, Getchevski S, Claggett B, Rizkala A, Lukashevich I, O'Meara E, Ryan JJ, Shah SJ, Mullens W, Zile MR, Lam CSP, McMurray JJV, Solomon SD; PARAGON-HF Investigators. Echocardiographic Features of Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction. J Am Coll Cardiol. 2019 Dec 10;74(23):2858-2873. doi: 10.1016/j.jacc.2019.09.063.

Results Reference

derived

PubMed Identifier

31736342

Citation

Solomon SD, Vaduganathan M, L Claggett B, Packer M, Zile M, Swedberg K, Rouleau J, A Pfeffer M, Desai A, Lund LH, Kober L, Anand I, Sweitzer N, Linssen G, Merkely B, Luis Arango J, Vinereanu D, Chen CH, Senni M, Sibulo A, Boytsov S, Shi V, Rizkala A, Lefkowitz M, McMurray JJV. Sacubitril/Valsartan Across the Spectrum of Ejection Fraction in Heart Failure. Circulation. 2020 Feb 4;141(5):352-361. doi: 10.1161/CIRCULATIONAHA.119.044586. Epub 2019 Nov 17.

Results Reference

derived

PubMed Identifier

31736337

Citation

McMurray JJV, Jackson AM, Lam CSP, Redfield MM, Anand IS, Ge J, Lefkowitz MP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Rizkala AR, Sabarwal SV, Shah AM, Shah SJ, Shi VC, van Veldhuisen DJ, Zannad F, Zile MR, Cikes M, Goncalvesova E, Katova T, Kosztin A, Lelonek M, Sweitzer N, Vardeny O, Claggett B, Jhund PS, Solomon SD. Effects of Sacubitril-Valsartan Versus Valsartan in Women Compared With Men With Heart Failure and Preserved Ejection Fraction: Insights From PARAGON-HF. Circulation. 2020 Feb 4;141(5):338-351. doi: 10.1161/CIRCULATIONAHA.119.044491. Epub 2019 Nov 17.

Results Reference

derived

PubMed Identifier

31726194

Citation

Vaduganathan M, Claggett BL, Desai AS, Anker SD, Perrone SV, Janssens S, Milicic D, Arango JL, Packer M, Shi VC, Lefkowitz MP, McMurray JJV, Solomon SD. Prior Heart Failure Hospitalization, Clinical Outcomes, and Response to Sacubitril/Valsartan Compared With Valsartan in HFpEF. J Am Coll Cardiol. 2020 Jan 28;75(3):245-254. doi: 10.1016/j.jacc.2019.11.003. Epub 2019 Nov 11.

Results Reference

derived

PubMed Identifier

31475794

Citation

Solomon SD, McMurray JJV, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, van Veldhuisen DJ, Zannad F, Zile MR, Desai AS, Claggett B, Jhund PS, Boytsov SA, Comin-Colet J, Cleland J, Dungen HD, Goncalvesova E, Katova T, Kerr Saraiva JF, Lelonek M, Merkely B, Senni M, Shah SJ, Zhou J, Rizkala AR, Gong J, Shi VC, Lefkowitz MP; PARAGON-HF Investigators and Committees. Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction. N Engl J Med. 2019 Oct 24;381(17):1609-1620. doi: 10.1056/NEJMoa1908655. Epub 2019 Sep 1.

Results Reference

derived

PubMed Identifier

31302043

Citation

Chandra A, Vaduganathan M, Lewis EF, Claggett BL, Rizkala AR, Wang W, Lefkowitz MP, Shi VC, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, Van Veldhuisen DJ, Zannad F, Zile MR, McMurray JJV, Solomon SD; PARAGON-HF Investigators. Health-Related Quality of Life in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Trial. JACC Heart Fail. 2019 Oct;7(10):862-874. doi: 10.1016/j.jchf.2019.05.015. Epub 2019 Jul 10.

Results Reference

derived

PubMed Identifier

29980595

Citation

Solomon SD, Rizkala AR, Lefkowitz MP, Shi VC, Gong J, Anavekar N, Anker SD, Arango JL, Arenas JL, Atar D, Ben-Gal T, Boytsov SA, Chen CH, Chopra VK, Cleland J, Comin-Colet J, Duengen HD, Echeverria Correa LE, Filippatos G, Flammer AJ, Galinier M, Godoy A, Goncalvesova E, Janssens S, Katova T, Kober L, Lelonek M, Linssen G, Lund LH, O'Meara E, Merkely B, Milicic D, Oh BH, Perrone SV, Ranjith N, Saito Y, Saraiva JF, Shah S, Seferovic PM, Senni M, Sibulo AS Jr, Sim D, Sweitzer NK, Taurio J, Vinereanu D, Vrtovec B, Widimsky J Jr, Yilmaz MB, Zhou J, Zweiker R, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, Van Veldhuisen DJ, Zannad F, Zile MR, McMurray JJV. Baseline Characteristics of Patients With Heart Failure and Preserved Ejection Fraction in the PARAGON-HF Trial. Circ Heart Fail. 2018 Jul;11(7):e004962. doi: 10.1161/CIRCHEARTFAILURE.118.004962.

Results Reference

derived

PubMed Identifier

29890892

Citation

Mutze T, Glimm E, Schmidli H, Friede T. Group sequential designs with robust semiparametric recurrent event models. Stat Methods Med Res. 2019 Aug;28(8):2385-2403. doi: 10.1177/0962280218780538. Epub 2018 Jun 11.

Results Reference

derived

PubMed Identifier

28662936

Citation

Solomon SD, Rizkala AR, Gong J, Wang W, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, Van Veldhuisen DJ, Zannad F, Zile MR, Desai AS, Shi VC, Lefkowitz MP, McMurray JJV. Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction: Rationale and Design of the PARAGON-HF Trial. JACC Heart Fail. 2017 Jul;5(7):471-482. doi: 10.1016/j.jchf.2017.04.013. Epub 2017 Jun 26.

Results Reference

derived

PubMed Identifier

25415957

Citation

Rossi A, Gheorghiade M, Triposkiadis F, Solomon SD, Pieske B, Butler J. Left atrium in heart failure with preserved ejection fraction: structure, function, and significance. Circ Heart Fail. 2014 Nov;7(6):1042-9. doi: 10.1161/CIRCHEARTFAILURE.114.001276. No abstract available.

Results Reference

derived

Learn more about this trial

Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction

We'll reach out to this number within 24 hrs

Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction (PARAGON-HF)

Heart Failure With Preserved Ejection Fraction

About this trial

Eligibility Criteria

Sites / Locations

Arms of the Study

Arm 1

Arm 2

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

1. Study Identification

2. Study Status

3. Sponsor/Collaborators

4. Oversight

5. Study Description

6. Conditions and Keywords

7. Study Design

8. Arms, Groups, and Interventions

10. Eligibility

12. IPD Sharing Statement

Learn more about this trial