Neurobiology of Language Recovery in Aphasia: Natural History and Treatment-Induced Recovery
Aphasia, Dysgraphia, Anomia
About this trial
This is an interventional treatment trial for Aphasia focused on measuring Aphasia, Dysgraphia, Anomia, Agrammatism, Stroke, Language Recovery, Treatment, Biomarkers of Recovery
Eligibility Criteria
Inclusion Criteria:
- Aphasia following a stroke
- Stoke was at least 1 year ago
- Medically stable
- Right-handed
- Normal or 'corrected to normal' vision and hearing
- English as primary language
- At least a high school education
Exclusion Criteria:
- History of neurological disease, head trauma, psychiatric disorders, alcoholism, or developmental speech, language, or learning disabilities
Sites / Locations
- Northwestern University
- Johns Hopkins University
- Boston University
- Harvard University
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Experimental
Naming Deficits
Spelling and/or Writing Deficits
Sentence Processing
Language treatment will focus on improving naming deficits in people who have aphasia. An experimental group will receive treatment focusing on naming objects and a control/natural history group will receive no treatment. Both groups will be assessed at baseline (week 0), at week 12, and at week 24.
Language treatment will focus on improving writing and/or spelling deficits in people who have aphasia. An experimental group will receive treatment focusing on improving spelling abilities and a control/natural history group will receive no treatment. Both groups will be assessed at baseline (week 0), at week 12, and at week 24.
Language treatment will focus on improving sentence comprehension and production deficits in people who have aphasia. An experimental group will receive treatment focusing on improving sentence processing and a control/natural history group will receive no treatment. Both groups will be assessed at baseline (week 0), at week 12, and at week 24.