Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture and Stress Loading.
Primary Purpose
Spinal Cord Injury, Degenerative Spinal Disease.
Status
Completed
Phase
Not Applicable
Locations
Taiwan
Study Type
Interventional
Intervention
imaging diagnostics
Sponsored by
About this trial
This is an interventional diagnostic trial for Spinal Cord Injury, Degenerative Spinal Disease.
Eligibility Criteria
Inclusion Criteria:
- Patients with a diagnosis of spinal cord injury and degenerative spinal disease
- Normal volunteers
Exclusion Criteria:
- Patients with cancer and infection.
Sites / Locations
- Tiffany Ting-Fang Shih
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
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Arm Description
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Outcomes
Primary Outcome Measures
Disc Perfusion
Secondary Outcome Measures
Full Information
NCT ID
NCT01973257
First Posted
October 24, 2013
Last Updated
October 31, 2013
Sponsor
National Taiwan University Hospital
1. Study Identification
Unique Protocol Identification Number
NCT01973257
Brief Title
Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture and Stress Loading.
Official Title
Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture and Stress Loading.
Study Type
Interventional
2. Study Status
Record Verification Date
October 2013
Overall Recruitment Status
Completed
Study Start Date
August 2007 (undefined)
Primary Completion Date
July 2010 (Actual)
Study Completion Date
July 2010 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
National Taiwan University Hospital
4. Oversight
5. Study Description
Brief Summary
The purpose of our study is to evaluate the perfusion of the IVDs and their diffusion ability by using the Dynamic contrast-enhanced MR perfusion technique and Diffusion weighted image with ADC value measurement, and to determine the relationship between these data and the degeneration of IVDs, the different posture, and different stress-loading status.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Spinal Cord Injury, Degenerative Spinal Disease.
7. Study Design
Primary Purpose
Diagnostic
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Participant
Enrollment
50 (Actual)
8. Arms, Groups, and Interventions
Arm Title
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Arm Type
Experimental
Arm Description
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Intervention Type
Procedure
Intervention Name(s)
imaging diagnostics
Primary Outcome Measure Information:
Title
Disc Perfusion
Time Frame
3 months
10. Eligibility
Sex
All
Minimum Age & Unit of Time
20 Years
Maximum Age & Unit of Time
80 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Patients with a diagnosis of spinal cord injury and degenerative spinal disease
Normal volunteers
Exclusion Criteria:
- Patients with cancer and infection.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Tiffany Ting-Fang Shih
Organizational Affiliation
Department of Medical Image, National Taiwan University Hospital
Official's Role
Principal Investigator
Facility Information:
Facility Name
Tiffany Ting-Fang Shih
City
Taipei
ZIP/Postal Code
100
Country
Taiwan
12. IPD Sharing Statement
Learn more about this trial
Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture and Stress Loading.
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