A Phase I/II to Assess Safety, Tolerability and Efficacy of DL-lactic Acid Syrup in Children With Recurrent Tonsillitis

This is an interventional treatment trial for Recurrent Tonsillitis in Children focused on measuring Recurrent Tonsillitis, Streptococcus A Read More

Inclusion Criteria:

• Children at the ages of 5-16.
• Patient is suffering from recurrent documented sore throat with at least 4 tonsillitis episodes during the preceding year (at least one verified by culture or rapid antigen testing for Streptococcus A).
• Patient with clinical presentation of irregular tonsils.
• Tonsils size graded between 2.5-4.
• Clinical diagnosis of bacterial known in recurrent pharyngeal-tonsillitis.
• Patient is willing to participate in the study and adhere to the study protocol
• Patient's guardian and/or Patient have signed informed consent.

Exclusion Criteria:

• Clinical diagnosis of acute tonsillitis/pharyngitis caused by Streptococcus pyogenes (Positive RSAT or microbial culture).
• Subjects who are known as Streptococcus pyogenes carriers
• Subject's requiring any other medication (topical or systemic) that may affect the course of the disease during the study period (e.g. antibiotics, sedating antihistamines), and/or did not completed 14 days from end of antibiotics treatment.
• Subjects with known hypersensitivity to lactose.
• Subject is suffering from peritonsillar abscess.
• Subject suffers from an active peptic ulcer
• Subjects who are suffering from any concomitant disease which in the judgment of the investigator will interfere with the conduct or interpretation of the study results.
• Subject is currently participating in another clinical study.