Transient Global Amnesia (TGA). Exploratory Study of the Default Mode Network During the Acute Phase (ICTUS)
Amnesia
About this trial
This is an interventional basic science trial for Amnesia focused on measuring Transient Global amnesia, fMRI, resting state
Eligibility Criteria
Inclusion Criteria:
Patient group
Clinical criteria of definition of transient global amnesia:
Acute disorder of anterograde memory observed by a witness. Respect of the other cognitive functions. No exclusion criteria for this diagnosis (see exclusion criteria section).
Hippocampal lesion in DWI MRI performed at 72h Clinical resolution of memory disorder within 24 hours
Control group No cognitive complaint No history of transient amnesia
Both groups Age between 40 and 80 years old
Exclusion Criteria:
Patient group Disturbance of consciousness or loss of identity Argument in favor of seizure disorders Presence of a neurological deficit focused
Both groups Recent head trauma Acute intoxication ethyl Taking drugs influencing memory processing Severe hypoglycemia Psychiatric disorder altering capacity for judgment Progressive neurological disorder with cognitive alteration Indication against MRI French language level insufficient to be appropriately involved in neuropsychological assessment, Administrative issues: unable to give informed about information, not covered by a social security system, refusal to sign the consent, patient under curators.
Pregnant Woman
Sites / Locations
- Chu Purpan
Arms of the Study
Arm 1
Arm 2
Experimental
Other
patient
control
each patient TGA will receive an evaluation in resting state IRMf during three successive visits: During the acute phase within 24 hours In 72 hours In 3 months
each control will receive an evaluation in resting state IRMf during three successive visits: During the acute phase within 24 hours In 72 hours In 3 months