Back to resultsNeuromuscular Electrical Stimulation Via the Peroneal Nerve Reduces Muscle Soreness Following Intermittent Exercise
Primary Purpose
Delayed Onset Muscle Soreness
Status
Completed
Phase
Not Applicable
Locations
United Kingdom
Study Type
Interventional
Intervention
control
graduated compression socks
neuromuscular electrical stimulation device
Sponsored by
About this trial
This is an interventional basic science trial for Delayed Onset Muscle Soreness focused on measuring delayed onset muscle soreness, muscle damage, muscle function, inflammation
Eligibility Criteria
Inclusion Criteria:
- healthy males
- currently playing intermittent sports (such as soccer, field hockey, rugby)
- currently representing their respective sports at either university, county, national or international levels
Exclusion Criteria:
- unhealthy males
- not currently playing intermittent sports (such as soccer, field hockey, rugby)
- not currently representing their respective sports at either university, county, national or international levels
- individuals indicating a history of cardiovascular, metabolic or haematological disorders
- participants reporting a sedentary lifestyle of less than three 30-min physical activity sessions per week
Sites / Locations
- School of Sport, Exercise and Health Sciences
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
experimental group
Arm Description
All participants performed a modified version of the Loughborough Intermittent Shuttle Test (LIST; Nicholas et al, 2000), an exercise protocol designed to simulate the activity pattern characteristics of intermittent sports such as soccer. The LIST was performed on three occasions, at the same time of day, each separated by approximately four weeks. Following each exercise trial, one of three recovery interventions were applied, the order of which were randomly allocated.
Outcomes
Primary Outcome Measures
Perceived muscle soreness (PMS)
perceived muscle soreness (PMS), often referred to as delayed onset muscle soreness (DOMS)
Secondary Outcome Measures
muscle strength
Full Information
NCT ID
NCT02018211
First Posted
December 17, 2013
Last Updated
June 25, 2015
Sponsor
Firstkind Ltd
Collaborators
Loughborough University
1. Study Identification
Unique Protocol Identification Number
NCT02018211
Brief Title
Neuromuscular Electrical Stimulation Via the Peroneal Nerve Reduces Muscle Soreness Following Intermittent Exercise
Official Title
Neuromuscular Electrical Stimulation Via the Peroneal Nerve Reduces Muscle Soreness Following Intermittent Exercise
Study Type
Interventional
2. Study Status
Record Verification Date
June 2015
Overall Recruitment Status
Completed
Study Start Date
December 2012 (undefined)
Primary Completion Date
March 2013 (Actual)
Study Completion Date
March 2013 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Firstkind Ltd
Collaborators
Loughborough University
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Numerous techniques are reported to enhance recovery following intense exercise, however there is equivocal support for such claims. A novel technique of neuromuscular electrical stimulation (NMES) via the peroneal nerve has been shown to augment limb blood flow which could enhance recovery following exercise. The present study examined the effects of NMES, compared to graduated compression socks on muscle soreness, strength, and markers of muscle damage and inflammation following intense intermittent exercise.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Delayed Onset Muscle Soreness
Keywords
delayed onset muscle soreness, muscle damage, muscle function, inflammation
7. Study Design
Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
21 (Actual)
8. Arms, Groups, and Interventions
Arm Title
experimental group
Arm Type
Experimental
Arm Description
All participants performed a modified version of the Loughborough Intermittent Shuttle Test (LIST; Nicholas et al, 2000), an exercise protocol designed to simulate the activity pattern characteristics of intermittent sports such as soccer. The LIST was performed on three occasions, at the same time of day, each separated by approximately four weeks. Following each exercise trial, one of three recovery interventions were applied, the order of which were randomly allocated.
Intervention Type
Other
Intervention Name(s)
control
Intervention Description
passive recovery following exercise test
Intervention Type
Device
Intervention Name(s)
graduated compression socks
Intervention Description
graduated compression socks worn after test exercise
Intervention Type
Device
Intervention Name(s)
neuromuscular electrical stimulation device
Other Intervention Name(s)
firefly device
Intervention Description
neuromuscular electrical stimulation device worn after test exercise
Primary Outcome Measure Information:
Title
Perceived muscle soreness (PMS)
Description
perceived muscle soreness (PMS), often referred to as delayed onset muscle soreness (DOMS)
Time Frame
72hrs
Secondary Outcome Measure Information:
Title
muscle strength
Time Frame
72hrs
Other Pre-specified Outcome Measures:
Title
measurement of CK and LDH activity and IL-6, CRP and TBAR concentrations
Description
markers of muscle damage and inflammation following intense intermittent exercise
Time Frame
72 hrs
10. Eligibility
Sex
Male
Minimum Age & Unit of Time
20 Years
Maximum Age & Unit of Time
22 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
healthy males
currently playing intermittent sports (such as soccer, field hockey, rugby)
currently representing their respective sports at either university, county, national or international levels
Exclusion Criteria:
unhealthy males
not currently playing intermittent sports (such as soccer, field hockey, rugby)
not currently representing their respective sports at either university, county, national or international levels
individuals indicating a history of cardiovascular, metabolic or haematological disorders
participants reporting a sedentary lifestyle of less than three 30-min physical activity sessions per week
Facility Information:
Facility Name
School of Sport, Exercise and Health Sciences
City
Loughborough
State/Province
Leicestershire
ZIP/Postal Code
LE11 3TU
Country
United Kingdom
12. IPD Sharing Statement
Citations:
PubMed Identifier
25011496
Citation
Ferguson RA, Dodd MJ, Paley VR. Neuromuscular electrical stimulation via the peroneal nerve is superior to graduated compression socks in reducing perceived muscle soreness following intense intermittent endurance exercise. Eur J Appl Physiol. 2014 Oct;114(10):2223-32. doi: 10.1007/s00421-014-2943-5. Epub 2014 Jul 11.
Results Reference
result
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Neuromuscular Electrical Stimulation Via the Peroneal Nerve Reduces Muscle Soreness Following Intermittent Exercise
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