A Nutritional Management Algorithm in Older Patients With Locally Advanced Esophageal Cancer
Localized Stage I-III Esophageal Cancer, Gastroesophageal Junction Cancer
About this trial
This is an interventional other trial for Localized Stage I-III Esophageal Cancer focused on measuring nutritional management algorithm, nutritional and functional assessments, 13-264
Eligibility Criteria
Inclusion Criteria:
- Patients must be ≥ age of 65; no maximum age limit.
- Patients who will receive induction chemotherapy followed by combined chemoradiotherapy at MSKCC for localized stage I-III esophageal or gastroesophageal junction cancer.
- Patients can receive chemoradiotherapy preoperatively prior to surgical resection or as definitive/primary chemoradiotherapy.
- Patients can be KPS ≥60, as long as primary provider feels that patient is candidate for combined modality chemoradiotherapy
- Be able to provide informed consent
Exclusion Criteria:
- Enrolled on a phase I trial
- Patients with a feeding tube previously placed.
- Not English-speaking
Sites / Locations
- Memorial Sloan Kettering Cancer Center at Basking Ridge (Consent Only)
- Memorial Sloan Kettering Monmouth (Consent Only)
- Memorial Sloan Kettering Bergen (Consent only)
- Memorial Sloan Kettering Cancer Center @ Suffolk (Consent Only)
- Memorial Sloan Kettering Cancer Center at Commack (Consent Only)
- Memorial Sloan Kettering West Harrison (Consent Only)
- Memorial Sloan Kettering Cancer Center
Arms of the Study
Arm 1
Experimental
nutritional management
The proposed study will be a prospective feasibility study of a nutritional management algorithm with risk-based guidelines in older adults (n=50) with newly diagnosed locally advanced esophageal cancer receiving preoperative or definitive chemoradiotherapy with an induction chemotherapy approach. Eligible patients must be age ≥ 65 years old. While all patients with esophageal cancer may benefit from this intervention, we wish to target the most vulnerable population (older patients who are at highest risk of malnutrition) in this pilot study.