Clinical, Anti-Inflammatory And Anti-Infective Properties Of Amniotic Membranes Used For Guided Tissue Regeneration
Chronic Periodontitis
About this trial
This is an interventional treatment trial for Chronic Periodontitis focused on measuring Periodontitis, Periodontal Regeneration, Amniotic membrane, Guided tissue regeneration, Anti-inflammatory, Periodontal Therapy.
Eligibility Criteria
Inclusion Criteria:
Systemically healthy chronic periodontitis patients within the age group of 30-55 years having at least 2 periodontal pockets ≥5 mm with at least 1 pocket in each quadrant showing radiographic evidence of vertical bone loss were included in the study. Assessment of suitability for GTR membrane placement was confirmed by transgingival probing to verify the presence of two well-contained interdental bone defects in as many quadrants.
Exclusion Criteria:
Smokers, medically compromised patients, pregnant women & lactating mothers and subjects receiving periodontal therapy in the 24 weeks (6-month)-period leading to the study were not included.
Sites / Locations
- SVS Institute of Dental Sciences, Mahabubnagar
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Amniotic Membrane
Control group (Hydroxyapatite only)
The test site was treated as follows; After placement and proper condensation of natural Hydroxyapatite graft in the defect, AM was cut based on defect anatomy of surgical site and then adapted over the bone graft and alveolar bone extending from base of the flap reflection to the tooth surface.
The control site was treated by graft placement (Hydroxyapatite) only