Quantitative Versus Qualitative Fecal Immunochemical Tests (FIT) to Prioritize Urgency of Colonoscopy Referral
Colorectal Cancer
About this trial
This is an interventional screening trial for Colorectal Cancer focused on measuring Colorectal cancer, Screening, Fecal occult blood, Fecal immunochemical test, Qualitative, Quantitative
Eligibility Criteria
Inclusion Criteria:
- Adults aged 50 years and above
Exclusion Criteria:
- Lower gastrointestinal tract symptoms such as diarrhoea, constipation, per rectal bleeding
- Personal history of colorectal tumour or cancer
- Family history of familial adenomatous polyposis or hereditary non-polyposis colorectal cancer
Sites / Locations
- University of Malaya Medical Centre
Arms of the Study
Arm 1
Arm 2
Other
Other
Qualitative fecal immunochemical test
Quantitative fecal immunochemical test
Stool samples will be tested with the qualitative fecal immunochemical test (qFIT), and will be stratified for colonoscopy as follows: >200 ng/dL - colonoscopy with one month 100-200 ng/dL - colonoscopy as per waiting list <100 ng/dL - no colonoscopy Cost analysis, anxiety scores and patient satisfaction scores will be calculated for all patients.
Stool samples will be tested with the quantitative fecal immunochemical test (FIT), and will be scheduled for colonoscopy as follows: Positive - colonoscopy as per waiting list Negative - no colonoscopy Cost analysis, anxiety scores and patient satisfaction scores will be calculated for all patients.