Wake and Light Therapy to In-patients With Major Depression: Efficacy, Predictors and Patient Experiences
Major Depression
About this trial
This is an interventional treatment trial for Major Depression focused on measuring Wake therapy, Sleep deprivation, Light therapy, Bipolar depression, Sleep-wake cycle, Major depression, Depression, Depressive Disorder, Major Behavioural Symptoms, Mood Disorders, Mental Disorders, Dyssomnias, Sleep Disorders, Affective Disorders
Eligibility Criteria
Inclusion Criteria:
- A diagnosis of major depression according to DSM-IV
- A score on the Hamilton Depression Scale, 17 items version of at least 18
- Patient with major depression as part of a bipolar disorder should be in adequate mood stabilising therapy at entry to the study
- Age of 18 to 65
- Speak and understand Danish
Exclusion Criteria:
- Severe suicidal ideation (a score of 3 or above on the Hamilton Depression Scale, 17-items version)
- Anxiety psychic or somatic (a score of 3 or above on the Hamilton Depression Scale, 17-items version)
- personality disorder according to DSM-IV
- Drug or alcohol abuse
- Psychotic disorder
- Pregnancy
- Glaucoma
- Epilepsy
Sites / Locations
- Mette Kragh
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
wake therapy, light therapy and sleep time stabilisation
treatment as usual
Wake therapy/sleep deprivation: Patients are awake for 36 hours three times in one week with a normal night of sleep between. Light therapy for 30 minutes daily in the entire study period. Sleep time stabilisation which involves psychoeducation regarding sleep hygiene and keeping the day-night cycle constant.