Effectiveness Study of Integrative Treatment for Pediatric Pneumonia
Pneumonia
About this trial
This is an interventional treatment trial for Pneumonia focused on measuring pneumonia, pediatrics, viral
Eligibility Criteria
Inclusion Criteria:
- children, aged 6 months to 59 months old, diagnosed as pneumonia according to western medicine diagnostic criteria;
- diagnosed as TCM pneumonia with gasp-cough, meeting wind-heat blocking lungs pattern (feng re bi fei zheng), and phlegm-heat blocking lungs pattern (tan re bi fei zheng);
- disease progression within 72 hours;
- those whose guardians understood and assigned the informed consent;
Exclusion Criteria:
- emergency pneumonia;
- complicated with other Pulmonary Disorders attack other than pneumonia;
- complicated with primary disease of heart (congenital heart disease, myocarditis, et al), liver (ALT, and AST ≥ 1.5 times of normal value ceiling), kidney (BUN > 8.2mmol/L, or serum CR > 104 µmol/L, et al) and blood system (anemia), and those with psychopathy;
- allergic to interventional medications;
- those who are participating or have participated in other clinical trials in 3 months.
Sites / Locations
- Affiliated Children's Hospital of Capital University of Medical Sciences
- Guangzhou Children's Hospital
- Affiliated Children's Hospital of Dalian Medical University
- Affiliated Hospital of Liaoning University of TCM
- Affiliated Hospital of Shandong University of TCM
- Affiliated Longhua Hospital of Shanghai University of TCM
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Injection, medications and application
Injection and medications
Intravenous injection: Xiyanping injection, produced by Jiangxi Qing Feng Pharmaceutical Co., Ltd; Medications: according to TCM syndrome differentiations; Wind-heat blocking lungs pattern (feng re bi fei zheng): Xiaoer Qingfei Heji (mixture), and Zhi Ke San (herbal powder to relieve cough) Phlegm-heat blocking lungs pattern (tan re bi fei zheng): Xiaoer Qingfei Heji (mixture), and Hua Tan San (herbal powder to remove phlegm) External application: Fuxiong San
Intravenous injection: Ribavirin Injection; Medications: symptomatic therapies Guaifenesin Syrup, for removing phlegm, relieving gasp-cough; Ibuprofen Suspension, and salbutamol in case of different symptoms