Study of the Impact of Dairy Fat on Cardiovascular Health. (HDL)
Metabolic Syndrome
About this trial
This is an interventional prevention trial for Metabolic Syndrome
Eligibility Criteria
Inclusion Criteria:
- Men and women age between 18 and 65 years
- Waist circumference >80.0 cm for women and >94.0 cm for men
- Plasma concentration of triglycerides >1.70 mmol / L
- Stable weight for 6 months before the start of the study (+/- 5lbs)
Exclusion Criteria:
- Men or women aged under 18 years or over 65 years
- History of CVD, type 2 diabetes or dyslipidaemia monogenic
- Endocrine disorders
- Smoking
- Lipid lowering medications or hypertension medications
- Food allergies and aversions to any food in the composition of experimental menus
- Subjects with special dietary habits (e.g. vegetarianism)
- Subject with a calculated Framingham risk of cardiovascular disease (CVD) > 20%
Sites / Locations
- Richardson Centre for Functional Foods and Nutraceuticals
- Institute of Nutrition and Funtional Foods
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Experimental
Experimental
Experimental
Experimental
Experimental
Cheese diet
Butter diet
CHO diet
MUFA diet
PUFA diet
A 4-week experimental diet with all meals and foods be provided to participants, including 90g of regular cheddar cheese daily per 2500 kcal. The diet will contain 13% of saturated fat (SFA), 14% of mono-unsaturated fat (MUFA), 5% of polyunsaturated fat (PUFA) and 53% of carbohydrate (CHO).
A 4-week experimental diet with all meals and foods be provided to participants, the diet will contain 13% of SFA mostly from butter. The diet will contain 14% of MUFA, 5% of PUFA and 53% of CHO.
A 4-week experimental diet with all meals and foods will provided to participants. The diet will contain 60% of CHO, 6% of SFA, 14% of MUFA and 5% of PUFA.
A 4-week experimental diet with all meals and foods be provided to participants. The diet will contain 21% of MUFA, 6% of SFA, 5% of PUFA and 53% of CHO.
A 4-week experimental diet with all meals and foods will be provided to participants. The diet will contain 12% of PUFA, 14% of MUFA, 6% of SFA and 53% of CHO.