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The Relationship Between Metamemory and Memory in Old Age (M&Mresearch)

Primary Purpose

Mild Cognitive Impairment

Status

Unknown status

Phase

Not Applicable

Locations

Hong Kong

Study Type

Interventional

Intervention

Metamemory Cognitive Intervention

About this trial

This is an interventional treatment trial for Mild Cognitive Impairment focused on measuring metamemory, memory, mild cognitive impairment

Eligibility Criteria

65 Years - undefined (Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

Study 1:

Participants are Chinese elderly of age 65 or above and they speak Cantonese as their primary language. They are to be recruited from a convenience sample of clients who are without cognitive problems and are attending service in the Elderly Health Centres (EHC) of the Elderly Health Service of the Department of Health, Hong Kong Special Administrative Region Government (HKSARG).

Study 2:

In addition to the inclusion criteria of Study 1, EHC members with confirmed dementia, suspected dementia, and suspected MCI will also be invited to participate in Study 2. However, confirmed demented clients and suspected demented clients must show their capacity to appraise by passing Quality of Life Appraisal Inventory (CapQOL) (Wong, J.G.W.S. et al., 2005) before they are accepted to the Study. All clients are recruited upon consent.

Study 3:

Suspected MCI participants of Study 2 with below average memory self-efficacy assessed to have MCI (according to operational definition) will be invited and recruited to Study 3 upon consent. In the present research, MCI is defined operationally according to prior local studies and determined with reference to the educational level-adjusted cutoff scores of Chinese Mini Mental Status Examination (CMMSE) and Abbreviated version of Memory Inventory for the Chinese combined (Lam, L. C.W. & et al., 2005; Lam, L.C.W. & et al., 2008).

Exclusion Criteria:

The presence of currently active medical conditions potentially affecting cognition e.g. vitamin B12 deficiency, hypothyroidism, chronic alcoholism, delirium, and active psychiatric disorders e.g. schizophrenia
Other conditions that might affect cognitive competency e.g. aphasia, severe visual or hearing impairment.

Sites / Locations

Research Site

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

lifestyle counseling

Arm Description

Metamemory Cognitive Intervention

Outcomes

Primary Outcome Measures

Objective Memory Measures

change from baseline in Hong Kong List Learning Test, 2nd Edition (HKLLT, Chan, A.S., 2006) for verbal episodic memory

Objective Memory Measures

Change from baseline in Figure Recognition of Memory Assessment Scale (MAS, Williams, 1991) for visual episodic memory

Objective Memory Measures

Change from baseline in Category Verbal Fluency Test (CVFT, categories to be chosen with reference to local studies by published by Chiu, H.F.K. et al., 1997 and Mok et al., 2004) for semantic memory

Objective Memory Measures

Change from baseline in Digit Span and Visual Spatial Span from (MAS, Williams, 1991) for verbal and visual memory working memory

Objective Memory Measures

Change from baseline in Event-based and Time-based Tasks for prospective memory (tasks to be developed with reference to the recommendations of Wilson, B.A. & et al., 2008)

Secondary Outcome Measures

Subjective Memory Measures

Change from baseline in the Chinese version of Memory Self-efficacy Scale (MSE, Frequency of Forgetting-10 Scale, Zelinski and Gilewski, 2004)

Subjective Memory Measures

Change from baseline in Chinese versions of the Abbreviated version of Memory Inventory for the Chinese (AMIC, Lam, Linda, C. W. & et al., 2005)

Subjective Memory Measures

Change from baseline in Chinese versions of the Anxiety about Memory (AM, a subscale of the Memory Functioning Questionnaire, Gilewski, Zelinski & Schaie, 1990, for Study 1 only)

Subjective Memory Measures

Change from baseline in Chinese versions of the Stereotypes about Memory Aging (SMA, Fort & Gana, 2009)

Full Information

NCT ID

NCT02113345

First Posted

March 12, 2014

Last Updated

April 9, 2014

Sponsor

The University of Hong Kong

1. Study Identification

Unique Protocol Identification Number

NCT02113345

Brief Title

The Relationship Between Metamemory and Memory in Old Age

Acronym

M&Mresearch

Official Title

The Relationship Between Metamemory and Memory in Old Age

Study Type

Interventional

2. Study Status

Record Verification Date

April 2014

Overall Recruitment Status

Unknown status

Study Start Date

April 2014 (undefined)

Primary Completion Date

March 2016 (Anticipated)

Study Completion Date

March 2016 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

The University of Hong Kong

4. Oversight

Data Monitoring Committee

5. Study Description

Brief Summary

The purpose of this research is to explore the relationship of metamemory and memory of elders and to evaluate the effectiveness of a metamemory cognitive intervention on elders with mild cognitive impairment and low memory self-efficacy.

Detailed Description

There are 3 studies in the present research. Study 1 is a reliability and validity study of the Chinese Metamemory Scales. Study 2 is a cross-sectional study to explore the relationship between metamemory and memory of elders encountered in Hong Kong primary health care setting.Study 3 is an Effectiveness Study of Metamemory Cognitive Intervention on elders with mild cognitive impairment and low memory self-efficacy. This research has the following aims and hypotheses: Research Aims: To evaluate the reliability and validity of the Chinese Metamemory Scales To explore the relationship between metamemory and memory of elders To evaluate the effectiveness of a metamemory cognitive intervention on Mild Cognitive Impairment (MCI) elders who have low memory self-efficacy Research Hypotheses: Study 1: The Chinese Metamemory Scales will show acceptable psychometric properties. Study 2: There is a positive correlation between metamemory (subjective memory) and memory (objective memory) and this relationship is mediated by stereotyped beliefs about memory ageing. Study 3: Comparing to Control Group, the Intervention Group will yield the following expected results: There is an improvement in objective memory measures post-training. There is an improvement in subjective memory measures post-training. There is an improvement in mood measures post-training.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Mild Cognitive Impairment

Keywords

metamemory, memory, mild cognitive impairment

7. Study Design

Primary Purpose

Treatment

Study Phase

Not Applicable

Interventional Study Model

Single Group Assignment

Masking

Participant

Allocation

N/A

Enrollment

60 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title

lifestyle counseling

Arm Type

Experimental

Arm Description

Metamemory Cognitive Intervention

Intervention Type

Behavioral

Intervention Name(s)

Metamemory Cognitive Intervention

Intervention Description

Metamemory Cognitive Intervention

Primary Outcome Measure Information:

Title

Objective Memory Measures

Description

change from baseline in Hong Kong List Learning Test, 2nd Edition (HKLLT, Chan, A.S., 2006) for verbal episodic memory

Time Frame

Baseline, post-intervention at week 16

Title

Objective Memory Measures

Description

Change from baseline in Figure Recognition of Memory Assessment Scale (MAS, Williams, 1991) for visual episodic memory

Time Frame

Baseline, post-intervention at week 16

Title

Objective Memory Measures

Description

Change from baseline in Category Verbal Fluency Test (CVFT, categories to be chosen with reference to local studies by published by Chiu, H.F.K. et al., 1997 and Mok et al., 2004) for semantic memory

Time Frame

Baseline, post-intervention at week 16

Title

Objective Memory Measures

Description

Change from baseline in Digit Span and Visual Spatial Span from (MAS, Williams, 1991) for verbal and visual memory working memory

Time Frame

Baseline, post-intervention at week 16

Title

Objective Memory Measures

Description

Change from baseline in Event-based and Time-based Tasks for prospective memory (tasks to be developed with reference to the recommendations of Wilson, B.A. & et al., 2008)

Time Frame

Baseline, post-intervention at week 16

Secondary Outcome Measure Information:

Title

Subjective Memory Measures

Description

Change from baseline in the Chinese version of Memory Self-efficacy Scale (MSE, Frequency of Forgetting-10 Scale, Zelinski and Gilewski, 2004)

Time Frame

Baseline, post-intervention at week 16

Title

Subjective Memory Measures

Description

Change from baseline in Chinese versions of the Abbreviated version of Memory Inventory for the Chinese (AMIC, Lam, Linda, C. W. & et al., 2005)

Time Frame

Baseline, post-intervention at week 16

Title

Subjective Memory Measures

Description

Change from baseline in Chinese versions of the Anxiety about Memory (AM, a subscale of the Memory Functioning Questionnaire, Gilewski, Zelinski & Schaie, 1990, for Study 1 only)

Time Frame

Baseline, post-intervention at week 16

Title

Subjective Memory Measures

Description

Change from baseline in Chinese versions of the Stereotypes about Memory Aging (SMA, Fort & Gana, 2009)

Time Frame

Baseline, post-intervention at week 16

10. Eligibility

Sex

All

Minimum Age & Unit of Time

65 Years

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria: Study 1: Participants are Chinese elderly of age 65 or above and they speak Cantonese as their primary language. They are to be recruited from a convenience sample of clients who are without cognitive problems and are attending service in the Elderly Health Centres (EHC) of the Elderly Health Service of the Department of Health, Hong Kong Special Administrative Region Government (HKSARG). Study 2: In addition to the inclusion criteria of Study 1, EHC members with confirmed dementia, suspected dementia, and suspected MCI will also be invited to participate in Study 2. However, confirmed demented clients and suspected demented clients must show their capacity to appraise by passing Quality of Life Appraisal Inventory (CapQOL) (Wong, J.G.W.S. et al., 2005) before they are accepted to the Study. All clients are recruited upon consent. Study 3: Suspected MCI participants of Study 2 with below average memory self-efficacy assessed to have MCI (according to operational definition) will be invited and recruited to Study 3 upon consent. In the present research, MCI is defined operationally according to prior local studies and determined with reference to the educational level-adjusted cutoff scores of Chinese Mini Mental Status Examination (CMMSE) and Abbreviated version of Memory Inventory for the Chinese combined (Lam, L. C.W. & et al., 2005; Lam, L.C.W. & et al., 2008). Exclusion Criteria: The presence of currently active medical conditions potentially affecting cognition e.g. vitamin B12 deficiency, hypothyroidism, chronic alcoholism, delirium, and active psychiatric disorders e.g. schizophrenia Other conditions that might affect cognitive competency e.g. aphasia, severe visual or hearing impairment.

Overall Study Officials:

First Name & Middle Initial & Last Name & Degree

Debbie SK Chow

Organizational Affiliation

The University of Hong Kong

Official's Role

Principal Investigator

Facility Information:

Facility Name

Research Site

City

Hong Kong

Country

Hong Kong

12. IPD Sharing Statement

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The Relationship Between Metamemory and Memory in Old Age

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