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Telomeres Parameters in Celiac Disease

Primary Purpose

Celiac Disease

Status
Unknown status
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
take blood samples
Sponsored by
Meir Medical Center
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional basic science trial for Celiac Disease focused on measuring celiac, telomere, telomerase

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • patients with celiac disease

Exclusion Criteria:

  • known malignancy
  • cannot sign informed consent
  • under age 18

Sites / Locations

    Arms of the Study

    Arm 1

    Arm Type

    Experimental

    Arm Label

    celiac disease

    Arm Description

    Outcomes

    Primary Outcome Measures

    telomere length

    Secondary Outcome Measures

    Full Information

    First Posted
    April 27, 2014
    Last Updated
    April 27, 2014
    Sponsor
    Meir Medical Center
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    1. Study Identification

    Unique Protocol Identification Number
    NCT02126033
    Brief Title
    Telomeres Parameters in Celiac Disease
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    April 2014
    Overall Recruitment Status
    Unknown status
    Study Start Date
    undefined (undefined)
    Primary Completion Date
    December 2015 (Anticipated)
    Study Completion Date
    undefined (undefined)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Principal Investigator
    Name of the Sponsor
    Meir Medical Center

    4. Oversight

    5. Study Description

    Brief Summary
    Celiac disease is an autoimmune process that causes destructive changes in the epithel of the small bowel and it is also a pre-malignant state (e.g lymphoma). The aim of the study is to examine telomere length and other parameters of genetic instability from peripheral blood lymphocytes of patients with celiac disease compared with healthy controls.

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Celiac Disease
    Keywords
    celiac, telomere, telomerase

    7. Study Design

    Primary Purpose
    Basic Science
    Study Phase
    Not Applicable
    Interventional Study Model
    Parallel Assignment
    Enrollment
    40 (Anticipated)

    8. Arms, Groups, and Interventions

    Arm Title
    celiac disease
    Arm Type
    Experimental
    Intervention Type
    Procedure
    Intervention Name(s)
    take blood samples
    Primary Outcome Measure Information:
    Title
    telomere length
    Time Frame
    at entry, after 6 months of gluten-free diet

    10. Eligibility

    Sex
    All
    Minimum Age & Unit of Time
    18 Years
    Accepts Healthy Volunteers
    Accepts Healthy Volunteers
    Eligibility Criteria
    Inclusion Criteria: patients with celiac disease Exclusion Criteria: known malignancy cannot sign informed consent under age 18

    12. IPD Sharing Statement

    Learn more about this trial

    Telomeres Parameters in Celiac Disease

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