Farming, Personal Protective Equipment, Nepal
Organophosphate Poisoning
About this trial
This is an interventional prevention trial for Organophosphate Poisoning focused on measuring Pesticides, Personal protective equipment, Developing countries, Tropical Climate
Eligibility Criteria
Inclusion
- Male (females usually wear national dresses considered to provide adequate protection (43).
- Age min. 18 years (implies being a legal worker).
- Grows crops in knee and abdomen height in given data collection period.
- Willing to spend 1.5-3 hours working with organophosphates under normal working conditions.
- Involved in farming minimum two years (implies being active).
- Usually sprays at least once in two weeks with organophosphates on average (implies being active).
- Uses a hand pressured backpack sprayer placed at home (necessary to complete non-intervention).
- Works with crops in 5-10 katha land (sufficient to apply organophosphates for given time).
- Has a mobile/landline number (necessary for easy contact).
Exclusion
- Has a helper during work with organophosphates (organophosphate exposure reduced).
- Is unwilling to stay organophosphate free one week prior to each of two experiment days (necessary for comparable measurements).
- Has any of the following conditions: liver disease/damage, alcoholic/viral hepatitis, acute infection, chronic malnutrition, heart attack, metastasis, obstructive jaundice, inflammation, uses pyridostigmine drugs (decreases or increases plasma cholinesterase) (44-46).
Sites / Locations
- FAPPEN - Field
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
LAPPE/DP
DP/LAPPE
In the LAPPE experiment the farmer will work as usual (mixing/loading/application/cleaning). wearing the LAPPE solution and carrying a new hand pressured backpack sprayer with a standardized nozzle. Conditions such as dosage, work practices and weather conditions will remain uncontrolled but be observed. After one week this process will be repeated wearing the DP solution.
In the DP experiment the farmer will work as usual (mixing/loading/application/cleaning) wearing the DP solution and carrying his usual backpack sprayer with his usual nozzle. Conditions such as dosage, work practices and weather conditions will remain uncontrolled but be observed. After one week this process will be repeated wearing the LAPPE solution.