Neuroprotective Therapy and Therapeutic Target in Emergency Department
Stroke, Dehydration
About this trial
This is an interventional treatment trial for Stroke focused on measuring stroke, dehydration, prognosis
Eligibility Criteria
Inclusion Criteria:
- acute stroke
Exclusion Criteria:
1.the time between the onset of neurological symptoms and emergency department presentation are more than 12 hours
2.required fibrinolytic therapy
3.required surgical intervention
4.underline disease including congestive heart failure, chronic renal failure ( Cr>2 mg/dl) , liver cirrhosis, chronic obstructive pulmonary disease
5. initial systolic blood pressure>200 or diastolic blood pressure > 120 mmHg
6.initial systolic blood pressure<100 mmHg
7.oxygen saturation less than 92% ( room air )
8. require diuretics
Sites / Locations
- Chang Gung Memorial Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
No Intervention
Bun/Cr based hydration
control
receive intravenous normal saline infusion and adjust infusion rate by Bun/Cr followed in the first 72 hours
receive intravenous normal saline infusion as clinician's adjustment