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A Clinical Trial of D1+ Versus D2 Distal Gastrectomy for Stage IB & II Advanced Gastric Cancer (ADDICT)

Primary Purpose

Gastric Adenocarcinoma

Status
Unknown status
Phase
Phase 3
Locations
Korea, Republic of
Study Type
Interventional
Intervention
D2 distal subtotal gastrectomy
D1+ distal subtotal gastrectomy
Sponsored by
National Cancer Center, Korea
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Gastric Adenocarcinoma

Eligibility Criteria

20 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria :

  • Histologically proven primary gastric adenocarcinoma
  • T1N1, T2N0, T2N1, T3N0, T3N1 by CT scan (AJCC 7th classification) and intraoperative surgical staging prior to resectional procedure
  • Location of primary tumor; antrum, or angle, lower body or mid body of the stomach
  • No evidence of other distant metastasis
  • Aged ≥ 20 year old
  • Performance status (PS) of 0 or 1 on Eastern Cooperative Oncology Group (ECOG) scale
  • No prior treatment of chemotherapy or radiation therapy against any other malignancies, and no prior treatment for gastric cancer including endoscopic mucosal resection

  • Adequate organ functions defined as indicated below:

    • WBC 3000/mm3 - 12,000/mm3
    • >serum Hemoglobin 8.0 g/dl
    • > serum Platelet 100 000/mm3
    • < serum AST 100 IU/l
    • <serum ALT 100 IU/l
    • < Total Bilirubin 2.0 mg/dl
  • Written signed informed consent

Exclusion Criteria :

  • Active double cancer (synchronous double cancer and metachronous double cancer within five disease-free years), excluding carcinoma in situ (lesions equal to intraepithelial or intramucosal cancer)
  • Gastric remnant cancer
  • ≥T4a in surgical staging before resection
  • N2 or more (number of metastatic lymph nodes ≥3) in CT scan
  • Histologically rare variants in WHO Classification such as Adenosquamous, Hepatoid, Squamous cell, Undifferentiated, , neuroendocrine carcinoma and others
  • Pregnant or breast-feeding women
  • Mental disorder(diagnosed with mental disorder on medical record)
  • systemic administration of corticosteroids(include Herbal Medication)
  • unstable angina or myocardial infarction within 6 months of the trial
  • unstable hypertension
  • severe respiratory disease requiring continuous oxygen therapy
  • previous upper abdominal surgery except laparoscopic cholecystectomy

Sites / Locations

  • Soon Chun Hyang University Hospital Cheonan
  • Konyang University Hospital
  • Kangwon National University Hospital
  • Dongguk University Gyeongju Hospital
  • Korea University Ansan Hospital
  • Dongguk University Medical Center
  • Hanyang University Guri Hospital
  • The Catholic University of Korea St. Vincent's Hospital
  • Ajou University Hospital
  • Gyengsang National University Hospital
  • National Cancer CenterRecruiting
  • Jeju National University Hospital
  • Chonbuk National University Hospital
  • Chosun University Hospital
  • Chonnam National University Hwasun Hospital
  • Kosin University Gospel Hospital
  • Pusan National University Hospital
  • Dong-A University Hospital
  • Dongnam Inst. Of Radiological & Medical Sciences
  • Inje University Haeundae Paik Hospital
  • Keimyung University Dongsan Medical Center
  • Kyungpook National University Hospital
  • Kungpook National University Hospital
  • Daegu Veterans Hospital
  • Yeungnam University Medical Center
  • Daegu Catholic Univ. Medical Center
  • Chungnam National University Hospital
  • Inha University Hospital
  • The Catholic University of Korea Incheon St. Mary's Hospital
  • Gachon University Gill Medical Center
  • Seoul National University Hospital
  • Seoul Red Cross Hospital
  • Severance Hospital
  • KyungHee University Medical Center
  • Hanyang University Medical Center
  • Kyung Hee University Hospital at Gangdong
  • VHS Medical Center
  • Samsung Medical Center
  • Gangnam Severance Hospital
  • Korea University Anam Hospital
  • The Catholic University of Korea St. Mary's Hospital
  • Asan Medical Center
  • Korea Cancer Center Hospital
  • Soon Chun Hyang University Hospital Seoul
  • Konkuk University Medical Center
  • Hallym University Sacred Heart Hospital
  • Korea University Guro Hospital
  • SMG-SNU Boramae Medical Center
  • Chung-Ang University Hospital
  • Ewha Womans University Medical Center

Arms of the Study

Arm 1

Arm 2

Arm Type

Active Comparator

Experimental

Arm Label

D2 distal subtotal gastrectomy

D1+ distal subtotal gastrectomy

Arm Description

D2 distal subtotal gastrectomy D2 includes Nos.1.3,4sb,4d,5,6,7,8a,9,11p,and 12a nodes in Japanese classification. Systemic en bloc lymph node dissection is mandatory. Resection margin should be negative for malignancy with intraoperative frozen biopsy

D1+ distal subtotal gastrectomy D1+ includes Nos.1,3,4sb,4d,5,6,7,8a,and 9 nodes in Japanese classification. Systemic en bloc lymph node dissection is mandatory. Resection margin should be negative for malignancy with intraoperative frozen biopsy

Outcomes

Primary Outcome Measures

overall survival
To test non-inferiority of survival of D1+ gastrectomy versus D2 gastrectomy for clinical stage I B & II advanced gastric cancer

Secondary Outcome Measures

disease free survival
3 year disease free survival
Subgroup analysis of Laparoscopic surgery versus open surgery
Subgroup analysis of Laparoscopic surgery versus open surgery in terms of 3 year relapse free survival and 5 year overall survival
Operating time
Operating time
Early postoperative complications
Early postoperative complications
Long term postoperative complications
Long term postoperative complications
Quality of life of the patients in terms of European quality of life questionnaire (EQ-5D)
Quality of life of the patients in terms of European quality of life questionnaire (EQ-5D)
Overall cost for the treatment
Overall cost for the treatment (from operative day to discharge day)
Finding biomarkers predicting lymph node metastasis and recurrence
Finding biomarkers predicting lymph node metastasis and recurrence for prediction of lymph node metastasis and recurrence

Full Information

First Posted
March 4, 2014
Last Updated
April 18, 2016
Sponsor
National Cancer Center, Korea
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1. Study Identification

Unique Protocol Identification Number
NCT02144727
Brief Title
A Clinical Trial of D1+ Versus D2 Distal Gastrectomy for Stage IB & II Advanced Gastric Cancer
Acronym
ADDICT
Official Title
A Multicenter Randomized Clinical Trial of D1+ Versus D2 Distal Gastrectomy for Stage IB & II Advanced Gastric Cancer
Study Type
Interventional

2. Study Status

Record Verification Date
April 2016
Overall Recruitment Status
Unknown status
Study Start Date
January 2014 (undefined)
Primary Completion Date
December 2021 (Anticipated)
Study Completion Date
December 2021 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
National Cancer Center, Korea

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
In oncological aspect, D1+ lymph node dissection would be enough for early stage gastric cancer in advanced gastric cancer (stage IB/IIA/IIB ).
Detailed Description
■ Background of Hypothesis A. JCOG (Japanese Clinical Oncology Group) 9501 Study : Addition of aorta lymph node dissection to D2 lymph node dissection does not increase survival rate. Wide range of operation is not always the best treatment. If invasion rate can be kept as minimal as possible while maintaining survival rate, it can lead to more secure operation while also reducing the frequency of complication after the surgery. 20 It may be advantageous for patients in terms of operation time, cost, and quality of life. B. COACT 1001 study A previous study which compared the feasibility of lymph node dissection in open surgery and lapraroscopic surgery for advanced gastric cancer. 11p, 12a lymph node (D2) resection rate: 79.2% and 88.8% respectively in all advance gastric cancer. 11p, 12a lymph node (D2) metastasis rate: 1.9% and 2.9% respectively. Subgroup analysis 11p, 12a lymph node resection in cStage IB/IIA: 74.5-80.0% and 86.7-96.1% respectively. : 0% metastasis rate for both. lymph node dissection in cStage IIB/IIIA: 81.1-82.3% and 87.5-89.2% respectively.: metastasis rates are 2.1% and 2.4-12.1% respectively. Application: 11p and 12a lymph nodes, which belong in D2 lymph nodes, need to be resected in advance gastric cancer in IIB stage or higher. However, in earlier stages of advance gastric cancer, the probability of metastasis is very low; therefore, resection of D1+ lymph nodes, excluding 11p and 12a, is enough.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Gastric Adenocarcinoma

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
1880 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
D2 distal subtotal gastrectomy
Arm Type
Active Comparator
Arm Description
D2 distal subtotal gastrectomy D2 includes Nos.1.3,4sb,4d,5,6,7,8a,9,11p,and 12a nodes in Japanese classification. Systemic en bloc lymph node dissection is mandatory. Resection margin should be negative for malignancy with intraoperative frozen biopsy
Arm Title
D1+ distal subtotal gastrectomy
Arm Type
Experimental
Arm Description
D1+ distal subtotal gastrectomy D1+ includes Nos.1,3,4sb,4d,5,6,7,8a,and 9 nodes in Japanese classification. Systemic en bloc lymph node dissection is mandatory. Resection margin should be negative for malignancy with intraoperative frozen biopsy
Intervention Type
Procedure
Intervention Name(s)
D2 distal subtotal gastrectomy
Intervention Description
D2 includes Nos.1.3,4sb,4d,5,6,7,8a,9,11p,and 12a nodes in Japanese classification. Systemic en bloc lymph node dissection is mandatory. Resection margin should be negative for malignancy with intraoperative frozen biopsy.
Intervention Type
Procedure
Intervention Name(s)
D1+ distal subtotal gastrectomy
Intervention Description
D1+ includes Nos.1,3,4sb,4d,5,6,7,8a,and 9 nodes in Japanese classification. Systemic en bloc lymph node dissection is mandatory. Resection margin should be negative for malignancy with intraoperative frozen biopsy
Primary Outcome Measure Information:
Title
overall survival
Description
To test non-inferiority of survival of D1+ gastrectomy versus D2 gastrectomy for clinical stage I B & II advanced gastric cancer
Time Frame
5 year
Secondary Outcome Measure Information:
Title
disease free survival
Description
3 year disease free survival
Time Frame
3 year
Title
Subgroup analysis of Laparoscopic surgery versus open surgery
Description
Subgroup analysis of Laparoscopic surgery versus open surgery in terms of 3 year relapse free survival and 5 year overall survival
Time Frame
3 year , 5 year
Title
Operating time
Description
Operating time
Time Frame
op day
Title
Early postoperative complications
Description
Early postoperative complications
Time Frame
within 30 days
Title
Long term postoperative complications
Description
Long term postoperative complications
Time Frame
after 30 days
Title
Quality of life of the patients in terms of European quality of life questionnaire (EQ-5D)
Description
Quality of life of the patients in terms of European quality of life questionnaire (EQ-5D)
Time Frame
baseline, 1 week, 1month, 6 month, 1 year, 3 year
Title
Overall cost for the treatment
Description
Overall cost for the treatment (from operative day to discharge day)
Time Frame
operation day to discharge
Title
Finding biomarkers predicting lymph node metastasis and recurrence
Description
Finding biomarkers predicting lymph node metastasis and recurrence for prediction of lymph node metastasis and recurrence
Time Frame
3 year

10. Eligibility

Sex
All
Minimum Age & Unit of Time
20 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria : Histologically proven primary gastric adenocarcinoma T1N1, T2N0, T2N1, T3N0, T3N1 by CT scan (AJCC 7th classification) and intraoperative surgical staging prior to resectional procedure Location of primary tumor; antrum, or angle, lower body or mid body of the stomach No evidence of other distant metastasis Aged ≥ 20 year old Performance status (PS) of 0 or 1 on Eastern Cooperative Oncology Group (ECOG) scale No prior treatment of chemotherapy or radiation therapy against any other malignancies, and no prior treatment for gastric cancer including endoscopic mucosal resection Adequate organ functions defined as indicated below: WBC 3000/mm3 - 12,000/mm3 >serum Hemoglobin 8.0 g/dl > serum Platelet 100 000/mm3 < serum AST 100 IU/l <serum ALT 100 IU/l < Total Bilirubin 2.0 mg/dl Written signed informed consent Exclusion Criteria : Active double cancer (synchronous double cancer and metachronous double cancer within five disease-free years), excluding carcinoma in situ (lesions equal to intraepithelial or intramucosal cancer) Gastric remnant cancer ≥T4a in surgical staging before resection N2 or more (number of metastatic lymph nodes ≥3) in CT scan Histologically rare variants in WHO Classification such as Adenosquamous, Hepatoid, Squamous cell, Undifferentiated, , neuroendocrine carcinoma and others Pregnant or breast-feeding women Mental disorder(diagnosed with mental disorder on medical record) systemic administration of corticosteroids(include Herbal Medication) unstable angina or myocardial infarction within 6 months of the trial unstable hypertension severe respiratory disease requiring continuous oxygen therapy previous upper abdominal surgery except laparoscopic cholecystectomy
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Young Woo Kim, Ph.D
Phone
82-31-920-1635
Email
gskim@ncc.re.kr
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Young Woo Kim, PhD
Organizational Affiliation
National Cancer Center, Korea
Official's Role
Principal Investigator
Facility Information:
Facility Name
Soon Chun Hyang University Hospital Cheonan
City
Cheonan
State/Province
Chuncheongnam-Do
ZIP/Postal Code
330-721
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Moon Soo Lee, Dr
Phone
+82-41-570-2114
First Name & Middle Initial & Last Name & Degree
Moon Soo Lee, Dr
Facility Name
Konyang University Hospital
City
Metropolitan City Daejon
State/Province
Daejon
ZIP/Postal Code
302-718
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sang Eok Lee, Dr
Phone
+82-10-6432-6399
Email
srglee@hanmail.net
First Name & Middle Initial & Last Name & Degree
Sang Eok Lee, Dr
Facility Name
Kangwon National University Hospital
City
Chuncheon
State/Province
Gangwon-Do
ZIP/Postal Code
200-722
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sung Bae Park, Dr
Phone
+82-10-2001-8566
Email
bsb1971_kr@kangwon.ac.kr
First Name & Middle Initial & Last Name & Degree
Sung Bae Park, Dr
Facility Name
Dongguk University Gyeongju Hospital
City
Gyeongju
State/Province
Gyeongbuk
ZIP/Postal Code
780-350
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jung Min Bae, Dr
Phone
+82-54-770-8217
First Name & Middle Initial & Last Name & Degree
Jung Min Bae, Dr
Facility Name
Korea University Ansan Hospital
City
Ansan
State/Province
Gyeonggi-Do
ZIP/Postal Code
425-707
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jong Han Kim, Dr
Phone
+82-31-412-5030
Email
ppongttai@gmail.com
First Name & Middle Initial & Last Name & Degree
Jong Han Kim, Dr
Facility Name
Dongguk University Medical Center
City
Goyang
State/Province
Gyeonggi-Do
ZIP/Postal Code
410-773
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yong Hae Baik, Dr
Phone
+82-10-6320-9229
Email
Whitedrag@naver.com
First Name & Middle Initial & Last Name & Degree
Yong Hae Baik, Dr
Facility Name
Hanyang University Guri Hospital
City
Guri
State/Province
Gyeonggi-do
ZIP/Postal Code
471-701
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Min Gyu Kim, Dr
Phone
+82-31-560-2114
First Name & Middle Initial & Last Name & Degree
Min Gyu Kim, Dr
Facility Name
The Catholic University of Korea St. Vincent's Hospital
City
Suwon
State/Province
Gyeonggi-Do
ZIP/Postal Code
442-723
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hyung Min Chin, Dr
Phone
+82-31-249-7170
Email
hchin@catholic.ac.kr
Facility Name
Ajou University Hospital
City
Suwon
State/Province
Gyeonggi-Do
ZIP/Postal Code
443-380
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sang-Uk Han, Dr
Phone
+82-10-2911-9336
Email
hansu@ajou.ac.kr
First Name & Middle Initial & Last Name & Degree
Sang-Uk Han, Dr
Facility Name
Gyengsang National University Hospital
City
Jinjoo
State/Province
Gyeongsangnam-Do
ZIP/Postal Code
660-702
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Young Joon Lee, Dr
Phone
+82-10-5060-3214
Email
orangejulia@naver.com
First Name & Middle Initial & Last Name & Degree
Young Joon Lee, Dr
First Name & Middle Initial & Last Name & Degree
Sang Ho Jeong, Dr
Facility Name
National Cancer Center
City
Goyang
State/Province
Gyunggi-Do
ZIP/Postal Code
410-769
Country
Korea, Republic of
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Young Woo Kim, PhD.
Phone
+82-31-920-1635
Email
gskim@ncc.re.kr
First Name & Middle Initial & Last Name & Degree
Young Woo Kim, Ph.D
First Name & Middle Initial & Last Name & Degree
Keun Won Ryu, Ph.D
First Name & Middle Initial & Last Name & Degree
Hong Man Yoon, M.D.
First Name & Middle Initial & Last Name & Degree
Bang Wool Eom, M.D. M.S.
First Name & Middle Initial & Last Name & Degree
Myeong Chul Kook, Ph.D
First Name & Middle Initial & Last Name & Degree
Soo Jin Kim, Ph.D
First Name & Middle Initial & Last Name & Degree
Byung Ho Nam, Ph.D
Facility Name
Jeju National University Hospital
City
Jeju
State/Province
Jeju Special Self-Governing Province
ZIP/Postal Code
690-767
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
In Ho Jeong, Dr
Phone
+82-10-3644-2240
Email
41056@naver.com
First Name & Middle Initial & Last Name & Degree
In Ho Jeong, Dr
Facility Name
Chonbuk National University Hospital
City
Jeonju
State/Province
Jellabuk-Do
ZIP/Postal Code
561-712
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Doo Hyun Yang, Dr
Phone
+82-10-4905-6291
Email
ydh@chonbuk.ac.kr
First Name & Middle Initial & Last Name & Degree
Chan Young Kim, Dr
First Name & Middle Initial & Last Name & Degree
Doo Hyun Yang, Dr
First Name & Middle Initial & Last Name & Degree
Se-Yul Lee, Dr
Facility Name
Chosun University Hospital
City
Gwangju
State/Province
Jellanam-Do
ZIP/Postal Code
501-717
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Young Don Min, Dr
Phone
+82-62-220-3114
First Name & Middle Initial & Last Name & Degree
Sung Soo Kim, Dr
First Name & Middle Initial & Last Name & Degree
Young Don Min, Dr
Facility Name
Chonnam National University Hwasun Hospital
City
Hwasun-Gun
State/Province
Jellanam-Do
ZIP/Postal Code
519-763
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Young Kyu Park, Dr
Phone
+82-10-7173-1196
Email
parkyk@jnu.ac.kr
First Name & Middle Initial & Last Name & Degree
Young Kyu Park, Dr
First Name & Middle Initial & Last Name & Degree
Sung-Yub Rhu, Dr
First Name & Middle Initial & Last Name & Degree
Mi Ran Jung, Dr
First Name & Middle Initial & Last Name & Degree
Oh Jeong, Dr
Facility Name
Kosin University Gospel Hospital
City
Busan
ZIP/Postal Code
602-702
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sang Ho Lee, Dr
Phone
+82-10-2867-8177
Email
gslsh@kosinmed.or.kr
First Name & Middle Initial & Last Name & Degree
Kyung Won Seo, Dr
First Name & Middle Initial & Last Name & Degree
Ki Young Yoon, Dr
First Name & Middle Initial & Last Name & Degree
Sang Ho Lee, Dr
Facility Name
Pusan National University Hospital
City
Busan
ZIP/Postal Code
602-739
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Dong Heon Kim, Dr
Phone
+82-10-4004-1134
Email
kdhun@pusan.ac.kr
First Name & Middle Initial & Last Name & Degree
Dae Hwan Kim, Dr
First Name & Middle Initial & Last Name & Degree
Dong Heon Kim, Dr
Facility Name
Dong-A University Hospital
City
Busan
ZIP/Postal Code
602-812
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ki-Han Kim, Dr
Phone
+82-51-240-2643
First Name & Middle Initial & Last Name & Degree
Ki-Han Kim, Dr
First Name & Middle Initial & Last Name & Degree
Min Chan Kim, Dr
Facility Name
Dongnam Inst. Of Radiological & Medical Sciences
City
Busan
ZIP/Postal Code
619-953
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jae-Seok Min, Dr
Phone
+82-10-9567-9488
Email
mdoogy@hanmail.net
First Name & Middle Initial & Last Name & Degree
Jae-Seok Min, Dr
Facility Name
Inje University Haeundae Paik Hospital
City
Busan
ZIP/Postal Code
Busan 612-896
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Byoung-Jo Suh, Dr
Phone
+82-11-899-7365
Email
oltx62@hotmail.com
First Name & Middle Initial & Last Name & Degree
Byoung-Jo Suh, Dr
First Name & Middle Initial & Last Name & Degree
Sung-Jin Oh, Dr
Facility Name
Keimyung University Dongsan Medical Center
City
Daegu
ZIP/Postal Code
700-712
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Seung Wan Ryu, Dr
Phone
+82-11-522-9659
Email
gsman@dsmc.or.kr
First Name & Middle Initial & Last Name & Degree
Seung Wan Ryu, Dr
First Name & Middle Initial & Last Name & Degree
Young Gil Son, Dr
Facility Name
Kyungpook National University Hospital
City
Daegu
ZIP/Postal Code
700-721
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ho Young Chung, Dr
Phone
+82-53-200-5601
First Name & Middle Initial & Last Name & Degree
Ho Young Chung, Dr
Facility Name
Kungpook National University Hospital
City
Daegu
ZIP/Postal Code
702-210
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wansik Yu, Dr
Phone
+82-10-9069-0365
Email
wyu@knu.ac.kr
First Name & Middle Initial & Last Name & Degree
O Kyoung Kwon, Dr
First Name & Middle Initial & Last Name & Degree
Wansik Yu, Dr
Facility Name
Daegu Veterans Hospital
City
Daegu
ZIP/Postal Code
704-802
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Taebong Kim, Dr
Phone
+82-10-4137-8022
Email
tkimchr@medigate.net
First Name & Middle Initial & Last Name & Degree
Taebong Kim, Dr
Facility Name
Yeungnam University Medical Center
City
Daegu
ZIP/Postal Code
705-703
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Se Won Kim, Dr
Email
kswgs@ynu.ac.kr
First Name & Middle Initial & Last Name & Degree
Se Won Kim, Dr
Facility Name
Daegu Catholic Univ. Medical Center
City
Daegu
ZIP/Postal Code
705-718
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hyun Dong Chae, Dr
Phone
+82-53-650-4065
Email
surgery@cu.ac.kr
First Name & Middle Initial & Last Name & Degree
Hyun Dong Chae, Dr
Facility Name
Chungnam National University Hospital
City
Daejeon
ZIP/Postal Code
301-721
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ji Young Sul, Dr
Phone
+82-10-5420-8369
Email
jsul@cnu.ac.kr
First Name & Middle Initial & Last Name & Degree
Ji Young Sul, Dr
Facility Name
Inha University Hospital
City
Incheon
ZIP/Postal Code
400-711
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yoon Seok Heo, Dr
Phone
+82-32-890-3431
Email
gshur@inha.ac.kr
First Name & Middle Initial & Last Name & Degree
Yoon Seok Heo, Dr
Facility Name
The Catholic University of Korea Incheon St. Mary's Hospital
City
Incheon
ZIP/Postal Code
403-720
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jinjo Kim, Dr
Phone
+82-2-1544-9004
Email
kjj@catholic.ac.kr
First Name & Middle Initial & Last Name & Degree
Jin-Jo Kim, Dr
First Name & Middle Initial & Last Name & Degree
Jung Sun Lee, Dr
First Name & Middle Initial & Last Name & Degree
Chang-Hyun Kim, Dr
Facility Name
Gachon University Gill Medical Center
City
Incheon
ZIP/Postal Code
405-760
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Woon Ki Lee, Dr
Phone
+82-10-8945-6007
Email
lwk@gilhospital.com
First Name & Middle Initial & Last Name & Degree
Woon Ki Lee, Dr
Facility Name
Seoul National University Hospital
City
Seoul
ZIP/Postal Code
110-744
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Han-Kwang Yang, Dr
Phone
+82-10-5216-0032
Email
hkyang@snu.ac.kr
First Name & Middle Initial & Last Name & Degree
Seong-Ho Kong, Dr
First Name & Middle Initial & Last Name & Degree
Yun-Suhk Suh, Dr
First Name & Middle Initial & Last Name & Degree
Han-Kwang Yang, Dr
First Name & Middle Initial & Last Name & Degree
Hyuk-Joon Lee, Dr
Facility Name
Seoul Red Cross Hospital
City
Seoul
ZIP/Postal Code
110-747
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Dong Gue Shin, Dr
Phone
+82-2-2002-8380
Email
shinedk@seoulmc.or.kr
First Name & Middle Initial & Last Name & Degree
Dong Gue Shin, Dr
Facility Name
Severance Hospital
City
Seoul
ZIP/Postal Code
120-752
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Woo-Jin Hyung, Dr
Phone
+82-2-2228-5170
First Name & Middle Initial & Last Name & Degree
In Kyu Kwon, Dr
First Name & Middle Initial & Last Name & Degree
Jong Won Kim, Dr
First Name & Middle Initial & Last Name & Degree
Hyung Il Kim, Dr
First Name & Middle Initial & Last Name & Degree
Sung Hoon Noh, Dr
First Name & Middle Initial & Last Name & Degree
Hyun-Baek Shin, Dr
First Name & Middle Initial & Last Name & Degree
Ji-Young Ahn, Dr
First Name & Middle Initial & Last Name & Degree
In Cho, Dr
First Name & Middle Initial & Last Name & Degree
Woo-Jin Hyung, Dr
Facility Name
KyungHee University Medical Center
City
Seoul
ZIP/Postal Code
130-872
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yong Ho Kim, Dr
Phone
+82-10-6540-8262
Email
kyjho@khmc.or.kr
First Name & Middle Initial & Last Name & Degree
Yong Ho Kim, Dr
Facility Name
Hanyang University Medical Center
City
Seoul
ZIP/Postal Code
133-792
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sung Joon Kwon, Dr
Phone
+82-10-2014-4398
Email
sjkwon@hanyang.ac.kr
First Name & Middle Initial & Last Name & Degree
Sung Joon Kwon, Dr
Facility Name
Kyung Hee University Hospital at Gangdong
City
Seoul
ZIP/Postal Code
134-727
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sung Il Choi, Dr
Phone
+82-10-3974-1654
Email
drchoi@khu.ac.kr
First Name & Middle Initial & Last Name & Degree
Sung Il Choi, Dr
Facility Name
VHS Medical Center
City
Seoul
ZIP/Postal Code
134-791
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ho-Geun Yoon, Dr
Phone
+82-2-2225-1234
First Name & Middle Initial & Last Name & Degree
Ho-Geun Yoon, Dr
Facility Name
Samsung Medical Center
City
Seoul
ZIP/Postal Code
135-710
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jae-Moon Bae, Ph.D
Phone
+82-10-8843-1625
Email
jmoonbae60@yahoo.co.kr
First Name & Middle Initial & Last Name & Degree
Jae-Moon Bae, Ph.D
First Name & Middle Initial & Last Name & Degree
Sang-Hyun Kim, Dr
First Name & Middle Initial & Last Name & Degree
Jun Ho Lee, Dr
Facility Name
Gangnam Severance Hospital
City
Seoul
ZIP/Postal Code
135-720
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Seung-Ho Choi, Dr
Phone
+82-10-3276-1466
Email
choish@yumc.yonsei.ac.kr
First Name & Middle Initial & Last Name & Degree
Seung-Ho Choi, Dr
Facility Name
Korea University Anam Hospital
City
Seoul
ZIP/Postal Code
136-705
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Seong Heum Park, Dr
Phone
+82-10-8992-3973
Email
pshchw@korea.ac.kr
First Name & Middle Initial & Last Name & Degree
Sung Heum Park, Dr
Facility Name
The Catholic University of Korea St. Mary's Hospital
City
Seoul
ZIP/Postal Code
137-701
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hae-Myung Jeon, Dr
Phone
+82-10-9066-5231
Email
hmjeon@catholic.ac.kr
First Name & Middle Initial & Last Name & Degree
Kyo-Young Song, Dr
First Name & Middle Initial & Last Name & Degree
Hae Myung Jeon, Dr
Facility Name
Asan Medical Center
City
Seoul
ZIP/Postal Code
138-736
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jeong Hwan Yook, Dr
Phone
+82-10-2258-8826
Email
jhyook@amc.seoul.kr
First Name & Middle Initial & Last Name & Degree
Byung-Sik Kim, Dr
First Name & Middle Initial & Last Name & Degree
Moon-Won Yoo, Dr
First Name & Middle Initial & Last Name & Degree
Jeong-Hwan Yook, Dr
Facility Name
Korea Cancer Center Hospital
City
Seoul
ZIP/Postal Code
139-709
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hang Jong Yu, Dr
Phone
+82-10-9253-5463
Email
imyst@hanafos.com
First Name & Middle Initial & Last Name & Degree
Hang Jong Yu, Dr
First Name & Middle Initial & Last Name & Degree
Jong In Lee, Dr
First Name & Middle Initial & Last Name & Degree
Sung Ho Jin, Dr
Facility Name
Soon Chun Hyang University Hospital Seoul
City
Seoul
ZIP/Postal Code
140-887
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yong Jin Kim, Dr
Phone
+82-10-5382-6758
Email
yjkim@hosp.sch.ac.kr
First Name & Middle Initial & Last Name & Degree
Yong Jin Kim, Dr
First Name & Middle Initial & Last Name & Degree
Ji Yeon Park, Dr
Facility Name
Konkuk University Medical Center
City
Seoul
ZIP/Postal Code
143-729
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ho-Yoon Bang, Dr
Phone
+82-10-6297-0629
Email
bangstca@kcch.re.kr
First Name & Middle Initial & Last Name & Degree
Ho-Yoon Bang, Dr
First Name & Middle Initial & Last Name & Degree
Pyoung Su Kim, Dr
Facility Name
Hallym University Sacred Heart Hospital
City
Seoul
ZIP/Postal Code
150-037
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Man Sup Lim, Dr
Phone
+82-10-3270-2988
Email
ellemes@hanmail.net
First Name & Middle Initial & Last Name & Degree
Dae Hyun Yang, Dr
First Name & Middle Initial & Last Name & Degree
Hae Wan Lee, Dr
First Name & Middle Initial & Last Name & Degree
Man Sup Lim, Dr
First Name & Middle Initial & Last Name & Degree
Ji Woong Cho, Dr
Facility Name
Korea University Guro Hospital
City
Seoul
ZIP/Postal Code
152-703
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Young Jae Mok, Dr
Phone
+82-10-2686-6587
Email
yjmok@kumc.ac.kr
First Name & Middle Initial & Last Name & Degree
Young Jae Mok, Dr
First Name & Middle Initial & Last Name & Degree
You Jin Jang, Dr
Facility Name
SMG-SNU Boramae Medical Center
City
Seoul
ZIP/Postal Code
156-707
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hye Sung Ahn, Dr
Phone
+82-2-2072-3797
First Name & Middle Initial & Last Name & Degree
Hye Sung Ahn, Dr
Facility Name
Chung-Ang University Hospital
City
Seoul
ZIP/Postal Code
156-755
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kyeung Chun Chi, Dr
Phone
+82-16-649-9874
Email
kcchi@cau.ac.kr
First Name & Middle Initial & Last Name & Degree
Joong-Min Park, Dr
First Name & Middle Initial & Last Name & Degree
Kyeung Chun Chi, Dr
Facility Name
Ewha Womans University Medical Center
City
Seoul
ZIP/Postal Code
158-710
Country
Korea, Republic of
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Joo Ho Lee, Dr
Email
gsljh@ewha.ac.kr
First Name & Middle Initial & Last Name & Degree
Yong Il Kim, Dr
First Name & Middle Initial & Last Name & Degree
Joo Ho Lee, Dr

12. IPD Sharing Statement

Learn more about this trial

A Clinical Trial of D1+ Versus D2 Distal Gastrectomy for Stage IB & II Advanced Gastric Cancer

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