High Intensity Training in Patients With Spinal and Bulbar Muscular Atrophy (HIT in Kennedy)
Spinal and Bulbar Muscular Atrophy, Healthy Subjects
About this trial
This is an interventional supportive care trial for Spinal and Bulbar Muscular Atrophy focused on measuring Kennedy's disease, Spinal and bulbar muscular atrophy, High Intensity Training, High Intensity Interval Training, HIT, HIIT, Training, Exercise, 10-20-30
Eligibility Criteria
Inclusion Criteria:
- Diagnosed with Spinal and bulbar muscular atrophy or
- Healthy control subjects matched individually with participating patients on age, sex, BMI and activity level.
Exclusion Criteria:
- More than 1 hour of fitness weekly before inclusion
- Other disease possibly confounding the results
- Pregnancy or breastfeeding
- Participations in other scientific studies wich could influence on the results during the last 30 days before inclusion.
- Physical and/or mental conditions preventing participating in the study protocol.
Sites / Locations
- Neuromuscular Research Unit
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Supervised high intensity training
Unsupervised High intensity training
8 weeks of supervised high intensity training, 10 minutes, 3 times a week (once a week supervised) on a cycle ergometer followed by 8 weeks of unsupervised optional training. Participants: Patients with Kennedy's disease or healthy control subjects (individually matched with patients). Participants: Patients with Kennedys disease and healthy control subjects.
8 week control period with no training followed by 8 weeks of unsupervised high intensity training on a cycle ergometer. Participants: Patients with Kennedy's disease.