Corneal Endothelial Cell Loss After Pneumatic Retinopexy for the Repair of Primary Rhegmatogenous Retinal Detachment
Rhegmatogenous Retinal Detachment
About this trial
This is an interventional treatment trial for Rhegmatogenous Retinal Detachment focused on measuring Corneal Endothelial Cell Loss, pneumatic retinopexy, vitrectomy
Eligibility Criteria
Inclusion Criteria:
- Age more than 18 years old.
- Patients with rhegmatogenous retinal detachment undergoing pneumatic retinopexy and pars plana vitrectomy.
- Patients on which specular microscopy and IOLMaster® can be performed without delaying their treatment (availability of a qualified operator).
- Decision makers able to give informed consent.
Exclusion Criteria:
- Unable to attend follow-up visits.
- History of previous intraocular surgery in surgical eye, except cataract extraction by phacoemulsification.
- Aphakia in surgical eye.
- Presence of an anterior chamber intraocular lens in surgical eye.
- Need for cryotherapy to treat the retinal break.
Sites / Locations
- Sunnybrook Health Sciences Centre
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
pneumatic retinopexy group
vitrectomy group
First, a 5/8-in 25-gauge needle will be used to perform an anterior chamber paracentesis, aiming to withdraw a minimum of 0.3 ml of aqueous fluid form the anterior chamber. Then, sulfur hexafluoride (SF6) will be injected in the vitreous cavity. The total volume of gas injected will exceed by 0.3 ml the amount of fluid withdrawn by the anterior chamber paracentesis (ex: 0.6 ml of SF6 would be injected after having withdrawn 0.3 ml). The laser retinopexy will be performed 48 hours later with laser.
Under certain circumstances, pneumatic retinopexy can't be considered as a primary treatment for rhegmatogenous retinal detachment. In these cases, the patient will be booked for urgent 25 G vitrectomy with intraoperative laser retinopexy and gas injection to treat retinal detachment