High-intensity Exercise and Fall Prevention Boot Camp for Parkinson's Disease
Parkinson's Disease
About this trial
This is an interventional treatment trial for Parkinson's Disease focused on measuring boot camp, exercise, balance training, fall prevention, falling, strength training
Eligibility Criteria
Inclusion Criteria:
- Neurologist-diagnosed idiopathic PD based on the UK PD brain bank criteria
- Aged 45-85
- Hoehn and Yahr stages 1-3 (mild to moderate PD)
- Participants do not anticipate a change in medication or surgical procedures in the next 8 months of the trial (2 months for the trial and 6 for the follow-up)
- Clearance from primary care physician to participate in the trial
- Must be stable on PD medication and DBS for 3 months prior to trial
Exclusion Criteria:
- Poorly controlled or unstable cardiovascular disease that precludes participation in exercise
- Moderate-to-severe dementia using the Montreal Cognitive Assessment (MoCA). We will exclude participants with a MoCA cut off score of <26/30. This cut off value has excellent sensitivity (90%) and specificity (75%).
- Inability to stand or walk for more than 10 minutes
- Other significant disorders that would limit endurance exercise participation (i.e., osteoarthritis, stroke, respiratory problems, traumatic brain injury, neuromuscular disease, pain)
- Already participating in a regular, vigorous exercise program (3X/week or more of >60% estimated maximum heart rate)
- Participants will be excluded from the trial if they are taking any medications that interfere with heart rate response to exercise
Sites / Locations
- University of Nevada, Las Vegas
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
High intensity boot camp
Usual care arm
Each of the two HIBCs will have 10 participants (20 total) with a 1:5 physical therapist-to-patient ratio. Each HIBC session will last 1.5 hours and will be held on 4 days of the week. Participants will be required to attend 3 of those 4 days but may attend all. Because this is a pragmatic trial, therapists will have some leeway to control the intensity and the modality of the exercise. However, the basic format of the HIBC will consist of the following exercise components: A. 30 minutes of moderate-high intensity aerobic exercise at 70%+ of estimated maximum heart rate; B. 15 minutes of strengthening the major muscle groups of the trunk and upper/lower extremities; C. 15 minutes of balance training; and, D. 15 minutes of rest and stretching. Participants will rotate through these four different exercise components in a circuit fashion.
The low intensity exercise group will participate in the Fitness Counts Exercise Program (FCEP) which is a basic low intensity, sitting and standing exercise program (10 minutes of stretching, 10 minutes of aerobic exercise (60% of heart rate maximum), and 10 minutes of strengthening). This exercise program was developed by the National Parkinson Foundation and is commonly used in PD exercise classes. The physical therapist-to-patient ratio will be 1:5. As there are two clinical sites, there will be 10 participants in each of the two boot camps (20 total). The FCEP will be 1 hour daily on four days of the week. Participants will be required to attend 3 days per week but may attend more if they are able.