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Associative Memory in Autism Spectrum Disorder (MEM-TA)

Primary Purpose

Autistic Disorder

Status
Unknown status
Phase
Not Applicable
Locations
France
Study Type
Interventional
Intervention
Electroencephalography
Neuropsychological assessment
Sponsored by
University Hospital, Caen
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional basic science trial for Autistic Disorder focused on measuring Autism Spectrum Disorder, Development, Memory, ERD

Eligibility Criteria

10 Years - 18 Years (Child, Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • Right handed children from 10 to 18 years old
  • Informed consent signed by the legal representative and adolescent himself.

  • Medical Examinations, psychopathology, and cognitive examination in accordance with inclusion and exclusion criteria specific to each population:

    • People with ASD:

      • Participants with ASD without mental retardation with a diagnosis in reference to the DSM V criteria
    • Controls : Participants without ASD

Main exclusion criteria:

  • mental retardation,
  • schizophrenia,
  • ADHD,
  • head injury with lost of consciousness

Sites / Locations

  • Caen University HospitalRecruiting

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Experimental

Arm Label

Patients

Control

Arm Description

Electroencephalography and neuropsychological tests in children with autism

Electroencephalography and neuropsychological tests in children without autism

Outcomes

Primary Outcome Measures

Index of discrimination obtained with the task of associative memory

Secondary Outcome Measures

Full Information

First Posted
October 9, 2014
Last Updated
February 19, 2018
Sponsor
University Hospital, Caen
Collaborators
Institut National de la Santé Et de la Recherche Médicale, France, Amiens University Hospital
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1. Study Identification

Unique Protocol Identification Number
NCT02265094
Brief Title
Associative Memory in Autism Spectrum Disorder
Acronym
MEM-TA
Official Title
Associative Memory in ASD Without Mental Retardation : Study in EEG and Neuropsychology
Study Type
Interventional

2. Study Status

Record Verification Date
February 2018
Overall Recruitment Status
Unknown status
Study Start Date
December 22, 2015 (Actual)
Primary Completion Date
December 2018 (Anticipated)
Study Completion Date
December 2019 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University Hospital, Caen
Collaborators
Institut National de la Santé Et de la Recherche Médicale, France, Amiens University Hospital

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
The aim of this study is to investigate the neural substrates of associative memory in Autism Spectrum Disorder using both behavioural and EEG assessments.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Autistic Disorder
Keywords
Autism Spectrum Disorder, Development, Memory, ERD

7. Study Design

Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Factorial Assignment
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
80 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Patients
Arm Type
Experimental
Arm Description
Electroencephalography and neuropsychological tests in children with autism
Arm Title
Control
Arm Type
Experimental
Arm Description
Electroencephalography and neuropsychological tests in children without autism
Intervention Type
Other
Intervention Name(s)
Electroencephalography
Intervention Description
EEG recordings during memory tests
Intervention Type
Behavioral
Intervention Name(s)
Neuropsychological assessment
Intervention Description
patterns of eye gaze during cognitive tests
Primary Outcome Measure Information:
Title
Index of discrimination obtained with the task of associative memory
Time Frame
4 years

10. Eligibility

Sex
All
Minimum Age & Unit of Time
10 Years
Maximum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: Right handed children from 10 to 18 years old Informed consent signed by the legal representative and adolescent himself. Medical Examinations, psychopathology, and cognitive examination in accordance with inclusion and exclusion criteria specific to each population: People with ASD: Participants with ASD without mental retardation with a diagnosis in reference to the DSM V criteria Controls : Participants without ASD Main exclusion criteria: mental retardation, schizophrenia, ADHD, head injury with lost of consciousness
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Bérengère GUILLERY-GIRARD, PhD
Phone
0231064347
Email
berengere.guillery@unicaen.fr
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Jean-Marc BALEYTE, MD
Organizational Affiliation
University Hospital, Caen
Official's Role
Principal Investigator
Facility Information:
Facility Name
Caen University Hospital
City
Caen
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Baleyte Jean Marc

12. IPD Sharing Statement

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Associative Memory in Autism Spectrum Disorder

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