A Comparison of Bed Rest Versus Moderate Activity in Preterm Premature Rupture of Membranes (PPROM) (PACT)
Preterm Premature Rupture of the Membranes, Physical Activity
About this trial
This is an interventional prevention trial for Preterm Premature Rupture of the Membranes focused on measuring Preterm Premature Rupture of the Membranes, Bedrest, Physical Activity
Eligibility Criteria
Inclusion Criteria:
- Pregnant
- Gestational age between 23 weeks 0 days - 32 weeks 0 days
- Diagnosed with preterm premature rupture of membranes
Exclusion Criteria:
- Cervical dilation greater than or equal to 3cm
- Active labor
- Evidence of infection
- Inability to provide informed consent
- Requirement for continuous fetal monitoring
Sites / Locations
- UCSD Health Sciences, Labor & Delivery
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
Bedrest
Moderate Activity
Bedrest is a standard recommendation for patients with PPROM. Subjects randomized to this arm of the study will undergo the following: Receive recommendation for bedrest (standard of care). Have maternal mood and muscle strength evaluated on enrollment and after delivery (observational study procedure). Wear a pedometer to measure activity when out of bed (observational study procedure).
Subjects randomized to this arm of the study will undergo the following: Receive recommendation to ambulate 150 feet, twice per day (interventional study procedure). Prior to each session of ambulation, an ultrasound will be performed to ensure adequate amniotic fluid volume and appropriate fetal position, and a fetal heart rate tracing will be obtained to ensure that there is reassuring fetal status (observational study procedure). During each session of ambulation, the fetal heart rate tracing will be monitored continuously (observational study procedure). Have maternal mood and muscle strength evaluated on enrollment and after delivery (observational study procedure). Wear a pedometer to measure activity when out of bed (observational study procedure).