Back to resultsRandomised Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over (ADAGE)
Primary Purpose
Colonic Adenocarcinoma
Status
Recruiting
Phase
Phase 3
Locations
France
Study Type
Interventional
Intervention
LV5FU2 or capectitabine
FOLFOX4 or XELOX
Observation
LV5FU2 or capecitabine
Sponsored by
About this trial
This is an interventional treatment trial for Colonic Adenocarcinoma focused on measuring Adjuvant chemotherapy in colonic adenocarcinoma in elderly
Eligibility Criteria
Inclusion Criteria:
- Age ≥ 70 years
- Patient considered able to receive chemotherapy
- Lee score detailed faxed to CRGA
- Stage III colon adenocarcinoma
- R0 resection of the primary tumor
- Start of the potential adjuvant chemotherapy within 12 weeks after surgery
- No prior chemotherapy for colon cancer
- Geriatric Self-administered questionnaire completed faxed to CRGA
- Geriatric Questionnaire completed by the team faxed to CRGA
- Effective contraception for men patients throughout treatment and for at least 6 months after discontinuation of oxaliplatin
- Consent signed
Exclusion Criteria:
- Other progressive disease (cancer uncontrolled for less than 2 years)
- Rectal Cancer (located less than 15 cm from the anal verge endoscopy or sub-peritoneal)
- ANC <2000 / mm3 for group 1 and ANC <1500 / mm3 for group 2 and platelets <100,000 / mm3 or hemoglobin <9 g / dL
- Neuropathy for patients in group 1
- Known deficit of dihydropyrimidine dehydrogenase (DPD)
- Patients with severe hepatic insufficiency
- Any contrindication to the drugs used in the study
- Inability to submit to medical follow-up for geographical, social or psychological reasons.
Sites / Locations
- CHU de Fort de FranceRecruiting
- CH d'AbbevilleRecruiting
- CROMGRecruiting
- Centre hospitalier du Pays d'AixRecruiting
- Centre hospitalier d'AlbiRecruiting
- Clinique Claude BernardRecruiting
- Clinique Claude BernardRecruiting
- Centre OncogardRecruiting
- Hôpital SudRecruiting
- ICO Site Paul PapinRecruiting
- CHU d'AngersRecruiting
- HOP PrivéRecruiting
- CH Victor DupouyRecruiting
- Hôpital Les BonnettesRecruiting
- Hôpital Privé BonnettesRecruiting
- Centre Hospitalier Ardèche MéridionaleRecruiting
- CH D'AuxerreRecruiting
- Institut Sainte CatherineRecruiting
- Hôpital Henri DuffautRecruiting
- Hôpital de BayeuxRecruiting
- CH Côte BasqueRecruiting
- Centre d'Oncologie et de Radiothérapie du Pays-BasqueRecruiting
- CH de BeauvaisRecruiting
- CH de BloisRecruiting
- CHU AvicenneRecruiting
- Polyclinique Bordeaux NordRecruiting
- Hôpital DuchenneRecruiting
- Hôpital Pierre OudotRecruiting
- Clinique Pasteur Saint EspritRecruiting
- CH de BéziersRecruiting
- CHU Côte de NacreRecruiting
- CHRecruiting
- Infirmerie Protestante de LyonRecruiting
- CH William MoreyRecruiting
- Hôpital Privé Sainte MarieRecruiting
- Centre Hospitalier Métropole SavoieRecruiting
- Centre Hospitalier Public du CotentinRecruiting
- CHRecruiting
- Centre Hospitalier GénéralRecruiting
- CHU EstaingRecruiting
- Hopitaux Civils de ColmarRecruiting
- Centre HospitalierRecruiting
- CHRecruiting
- Centre Hospitalier Sud FrancilienRecruiting
- Clinique des CèdresRecruiting
- Clinique des CèdresRecruiting
- Centre Hospitalier de DaxRecruiting
- Service de médecineRecruiting
- Hôpital François MitterandRecruiting
- Institut de Cancérologie de Bourgogne - GRRECCRecruiting
- Centre Goerges François LeclercRecruiting
- CHI Elbeuf-Louviers-Val de ReuilRecruiting
- CHRecruiting
- CHI de Fréjus Saint-RaphaëlRecruiting
- Centre médical des ForcillesRecruiting
- Centre HospitalierRecruiting
- Centre HospitalierRecruiting
- CHRecruiting
- CHU de Grenoble - Hôpital A. MichallonRecruiting
- CH Marne La Vallée-JossignyRecruiting
- CHD VendéeRecruiting
- Groupe Hospitalier de la Rochelle Ré-AunisRecruiting
- CHRecruiting
- CH du MansRecruiting
- Centre Oscar LambretRecruiting
- CHRU Hôpital Claude Huriez 4eme ESTRecruiting
- Clinique François ChénieuxRecruiting
- CHU DupuytrenRecruiting
- CHRecruiting
- CHBS - Hôpital du ScorffRecruiting
- Clinique de la SauvegardeRecruiting
- Clinique Mutualiste Eugène AndréRecruiting
- Hôpital Privé Jean MermozRecruiting
- CHU de Lyon - Croix RousseRecruiting
- CH ST Joseph-ST LucRecruiting
- Hôpital Edouard HerriotRecruiting
- Centre RadiologieRecruiting
- Hôpital Européen MarseilleRecruiting
- Hopital NordRecruiting
- CHU La TimoneRecruiting
- CH de MeauxRecruiting
- Hôpital LayneRecruiting
- Hôpital MonodRecruiting
- Centre HospitalierRecruiting
- Centre HospitalierRecruiting
- Centre Azuréen de CancérologieRecruiting
- Hôpital Privé du Confluent SASRecruiting
- Hôpital Américain de ParisRecruiting
- Hôpital Pierre BérégovoyRecruiting
- Centre Antoine LacassagneRecruiting
- Centre OncogardRecruiting
- CHU CarémeauRecruiting
- Hôpital de la SourceRecruiting
- Hôpital Privé des PeupliersRecruiting
- Hôpital Saint AntoineRecruiting
- HEGPRecruiting
- Hôpital CochinRecruiting
- Hôpital Saint LouisRecruiting
- Institut MontsourisRecruiting
- Pitié SalpêtièreRecruiting
- Centre HospitalierRecruiting
- Hôpital Haut LevequeRecruiting
- CHU Lyon SudRecruiting
- Centre CARIO - HCPARecruiting
- Hôpital de la MilétrieRecruiting
- CH Annecy GenevoisRecruiting
- Polyclinique FranchevilleRecruiting
- CHU Robert DebréRecruiting
- CHU de PontchaillouRecruiting
- Centre Eugène MarquisRecruiting
- CHRecruiting
- Hôpital Drome NordRecruiting
- CHU Charles NicolleRecruiting
- Clinique MathildeRecruiting
- Hôpital Privé Saint GrégoireRecruiting
- ICO - Site René GauducheauRecruiting
- Institut de Cancérologie Lucien NeuwirthRecruiting
- CHRecruiting
- Institut CurieRecruiting
- Polyclinique Côte Basque SudRecruiting
- Centre Hospitalier de Saint-MaloRecruiting
- Hôpital d'Instruction des Armées BeginRecruiting
- Polyclinique Saint ClaudeRecruiting
- CH SaintongeRecruiting
- CH MorlevatRecruiting
- CHRecruiting
- Centre HospitalierRecruiting
- CH Région Saint OmerRecruiting
- Clinique Sainte AnneRecruiting
- Centre Paul StraussRecruiting
- Hôpitaux du LemanRecruiting
- Hôpital Sainte MusseRecruiting
- Hôpital Sainte MusseRecruiting
- Clinique Saint Jean du LanguedocRecruiting
- Hôpitaux TrousseauRecruiting
- Centre HospitalierRecruiting
- CHU de Nancy-BradoisRecruiting
- Institut de Cancérologie de LorraineRecruiting
- Paul BrousseRecruiting
- Centre HospitalierRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm Type
Experimental
Experimental
Experimental
Experimental
Arm Label
GROUP1 -ARM A
GROUP1-ARMB
GROUP2- ARM C
GROUP2-ARM D
Arm Description
LV5FU2 or capecitabine
FOLFOX4 or XELOX
Observation
LV5FU2 or capecitabine
Outcomes
Primary Outcome Measures
The 3-year disease-free survival
Secondary Outcome Measures
Overal survival
Observed toxicities, graded according to NCI-CTC v4
Full Information
NCT ID
NCT02355379
First Posted
January 26, 2015
Last Updated
August 16, 2023
Sponsor
Federation Francophone de Cancerologie Digestive
1. Study Identification
Unique Protocol Identification Number
NCT02355379
Brief Title
Randomised Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over
Acronym
ADAGE
Official Title
Randomised Phase III Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over Intergroup Trial: Ffcd, Gercor, Gerico, Unicancer-gi
Study Type
Interventional
2. Study Status
Record Verification Date
August 2023
Overall Recruitment Status
Recruiting
Study Start Date
January 2015 (undefined)
Primary Completion Date
February 2024 (Anticipated)
Study Completion Date
August 2025 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Federation Francophone de Cancerologie Digestive
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
Colorectal cancer occurs mainly in elderly patients. Recent estimation showed that in France more than 50% of the patients diagnosed with a colorectal cancer are 70 years old or more. Adjuvant chemotherapy has demonstrated a benefit on disease-free survival and overall survival after a stage III colon cancer resection. Nevertheless adjuvant chemotherapy is poorly used in elderly patients. Prognostic improvement with chemotherapy based on 5FU is suggested by a post-hoc analysis of randomized prospective clinical trial. But elderly patients in this study were highly selected and patients older than 80 represented only 0.7% of the total population. Thus, there is still a concern about the benefit of adjuvant 5FU-based chemotherapy in very elderly unselected patients.
The recommended treatment for stage III adjuvant chemotherapy is a combination of fuoropyrimidine and oxaliplatin. Nevertheless oxaliplatin did not demonstrated survival advantage in elderly patients.
Altogether there are still two matters of debate:
First, is there a benefit of fluoropyrimidine-based adjuvant chemotherapy for unfit elderly patients?
Second, is there a benefit of oxaliplatin-based adjuvant chemotherapy for fit elderly patients? The aim of this randomized phase III study is to evaluate the benefit for disease-free survival of adjuvant chemotherapy in elderly patient and which chemotherapy.
The elderly patient population will be dichotomized into two groups according to physician's choice after a multidisciplinary evaluation involving a geriatrician, with two different randomization assignments. The patients with an expected life-expectancy below 4 years according Lee score are excluded of this study.
Some biological tumour abnormalities are more frequently observed in elderly (i.e. mismatch repair deficiency), therefore an evaluation of specific biological prognostic factors is needed in elderly population.
Detailed Description
Colorectal cancer occurs mainly in elderly patients. Recent estimation showed that in France more than 50% of the patients diagnosed with a colorectal cancer are 70 years old or more. Adjuvant chemotherapy has demonstrated a benefit on disease-free survival and overall survival after a stage III colon cancer resection. Nevertheless adjuvant chemotherapy is poorly used in elderly patients. Prognostic improvement with chemotherapy based on 5FU is suggested by a post-hoc analysis of randomized prospective clinical trial. But elderly patients in this study were highly selected and patients older than 80 represented only 0.7% of the total population. Thus, there is still a concern about the benefit of adjuvant 5FU-based chemotherapy in very elderly unselected patients.
The recommended treatment for stage III adjuvant chemotherapy is a combination of fuoropyrimidine and oxaliplatin. Nevertheless oxaliplatin did not demonstrated survival advantage in elderly patients.
Altogether there are still two matters of debate:
First, is there a benefit of fluoropyrimidine-based adjuvant chemotherapy for unfit elderly patients?
Second, is there a benefit of oxaliplatin-based adjuvant chemotherapy for fit elderly patients? The aim of this randomized phase III study is to evaluate the benefit for disease-free survival of adjuvant chemotherapy in elderly patient and which chemotherapy.
The elderly patient population will be dichotomized into two groups according to physician's choice after a multidisciplinary evaluation involving a geriatrician, with two different randomization assignments. The patients with an expected life-expectancy below 4 years according Lee score are excluded of this study.
Some biological tumour abnormalities are more frequently observed in elderly (i.e. mismatch repair deficiency), therefore an evaluation of specific biological prognostic factors is needed in elderly population.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Colonic Adenocarcinoma
Keywords
Adjuvant chemotherapy in colonic adenocarcinoma in elderly
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
774 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
GROUP1 -ARM A
Arm Type
Experimental
Arm Description
LV5FU2 or capecitabine
Arm Title
GROUP1-ARMB
Arm Type
Experimental
Arm Description
FOLFOX4 or XELOX
Arm Title
GROUP2- ARM C
Arm Type
Experimental
Arm Description
Observation
Arm Title
GROUP2-ARM D
Arm Type
Experimental
Arm Description
LV5FU2 or capecitabine
Intervention Type
Drug
Intervention Name(s)
LV5FU2 or capectitabine
Intervention Type
Drug
Intervention Name(s)
FOLFOX4 or XELOX
Intervention Type
Other
Intervention Name(s)
Observation
Intervention Type
Drug
Intervention Name(s)
LV5FU2 or capecitabine
Primary Outcome Measure Information:
Title
The 3-year disease-free survival
Time Frame
3 years after last patient in
Secondary Outcome Measure Information:
Title
Overal survival
Time Frame
5 years after last patient in
Title
Observed toxicities, graded according to NCI-CTC v4
Time Frame
3 years after last patient in
10. Eligibility
Sex
All
Minimum Age & Unit of Time
75 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Age ≥ 70 years
Patient considered able to receive chemotherapy
Lee score detailed faxed to CRGA
Stage III colon adenocarcinoma
R0 resection of the primary tumor
Start of the potential adjuvant chemotherapy within 12 weeks after surgery
No prior chemotherapy for colon cancer
Geriatric Self-administered questionnaire completed faxed to CRGA
Geriatric Questionnaire completed by the team faxed to CRGA
Effective contraception for men patients throughout treatment and for at least 6 months after discontinuation of oxaliplatin
Consent signed
Exclusion Criteria:
Other progressive disease (cancer uncontrolled for less than 2 years)
Rectal Cancer (located less than 15 cm from the anal verge endoscopy or sub-peritoneal)
ANC <2000 / mm3 for group 1 and ANC <1500 / mm3 for group 2 and platelets <100,000 / mm3 or hemoglobin <9 g / dL
Neuropathy for patients in group 1
Known deficit of dihydropyrimidine dehydrogenase (DPD)
Patients with severe hepatic insufficiency
Any contrindication to the drugs used in the study
Inability to submit to medical follow-up for geographical, social or psychological reasons.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Martina Schneider
Phone
+33 3 80 39 34 83
Email
martina.schneider@u-bourgogne.fr
First Name & Middle Initial & Last Name or Official Title & Degree
Jaique Cario
Phone
+33 3 80 39 34 86
Email
jaique.cario_isat@u-bourgogne.fr
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Thomas Aparicio, Pr
Organizational Affiliation
FFCD member
Official's Role
Principal Investigator
Facility Information:
Facility Name
CHU de Fort de France
City
Fort De France
State/Province
Guadeloupe
ZIP/Postal Code
97261
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Nathalie GROSSAT BERNADOU, Dr
Email
nathalie.grossat-bernadou@chu-martinique.fr
Facility Name
CH d'Abbeville
City
Abbeville CEDEX
ZIP/Postal Code
80142
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mathieu PAUWELS, Dr
Email
pauwels.mathieu@ch-abbeville.fr; pauwels.gastro@wanadoo.fr
Facility Name
CROMG
City
Agen
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Adela CAUCHOIS
Phone
05 53 69 12 00
First Name & Middle Initial & Last Name & Degree
Adela CAUCHOIS
First Name & Middle Initial & Last Name & Degree
Sévrine GUARNIERI
First Name & Middle Initial & Last Name & Degree
Xavier CARLES
First Name & Middle Initial & Last Name & Degree
Olivier BERNARD
Facility Name
Centre hospitalier du Pays d'Aix
City
Aix-en-Provence
ZIP/Postal Code
13616
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sophie NAHON BRISSONNEAU, Dr
Email
arc.emrc13@gmail.com
Facility Name
Centre hospitalier d'Albi
City
Albi
ZIP/Postal Code
81000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Nadia MUNSCH, Dr
Email
nadia.munsch@ch-albi.rss.fr
Facility Name
Clinique Claude Bernard
City
Albi
ZIP/Postal Code
81030
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yann BERGE, Dr
Email
berge@claude-bernard-albi.com
Facility Name
Clinique Claude Bernard
City
Albi
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yann BERGE
Email
berge@claude-bernard-albi.com
First Name & Middle Initial & Last Name & Degree
Yann BERGE
First Name & Middle Initial & Last Name & Degree
Philippe HOUYAU
First Name & Middle Initial & Last Name & Degree
Marie-Hélène GASPARD
First Name & Middle Initial & Last Name & Degree
Amaury SYLVESTRE
Facility Name
Centre Oncogard
City
Alès
ZIP/Postal Code
30103
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jacques CRETIN, Dr
Email
cretinjacques@yahoo.fr
Facility Name
Hôpital Sud
City
Amiens CEDEX 1
ZIP/Postal Code
80054
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Vincent HAUTEFEUILLE, Dr
Email
hautefeuille.vincent@chu-amiens.fr
Facility Name
ICO Site Paul Papin
City
Angers CEDEX 2
ZIP/Postal Code
49055
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sandrine HIRET, Dr
Email
Sandrine.hiret@ico.unicancer.fr
Facility Name
CHU d'Angers
City
Angers CEDEX 9
ZIP/Postal Code
49933
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Nathalie BAIZE, Dr
Email
nabaize@chu-angers.fr
Facility Name
HOP Privé
City
Annemasse
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Oxana SHESTAEVA
Email
o.shestaeva@ramsaygds.fr
First Name & Middle Initial & Last Name & Degree
Oxana SHESTAEVA
Facility Name
CH Victor Dupouy
City
Argenteuil
ZIP/Postal Code
95107
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Arnaud BOUTAN-LAROZE, Dr
Email
arnaud.boutan-laroze@ch-argenteuil.fr
Facility Name
Hôpital Les Bonnettes
City
Arras CEDEX
ZIP/Postal Code
62012
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Bruno HUGUENIN, Dr
Email
drbhuguenin@orange.fr
Facility Name
Hôpital Privé Bonnettes
City
Arras
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Bruno HUGUENIN
Email
drbhuguenin@orange.fr
First Name & Middle Initial & Last Name & Degree
Bruno HUGUENIN
First Name & Middle Initial & Last Name & Degree
Sophie BLANC
Facility Name
Centre Hospitalier Ardèche Méridionale
City
Aubenas CEDEX
ZIP/Postal Code
07205
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Brigitte VELAY, Dr
Email
brigitte.velay@ch-ardeche-meridionale.fr
Facility Name
CH D'Auxerre
City
Auxerre
ZIP/Postal Code
89000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Anne-Laure VILLING, Dr
Email
alvilling@ch-auxerre.fr
Facility Name
Institut Sainte Catherine
City
Avignon CEDEX
ZIP/Postal Code
84918
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Laurent MINEUR, Dr
Email
l.mineur@isc84.org
Facility Name
Hôpital Henri Duffaut
City
Avignon
ZIP/Postal Code
84902
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Olivier BOULAT, Dr
Email
OBoulat@ch-avignon.fr
Facility Name
Hôpital de Bayeux
City
Bayeux CEDEX
ZIP/Postal Code
14401
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Annie PEYTIER, Dr
Email
a.peytier@sih-bessin.fr
Facility Name
CH Côte Basque
City
Bayonne CEDEX
ZIP/Postal Code
64109
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Franck AUDEMAR, Dr
Email
faudemar@ch-cotebasque.fr
Facility Name
Centre d'Oncologie et de Radiothérapie du Pays-Basque
City
Bayonne
ZIP/Postal Code
64100
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Stéphane REMY, Dr
Email
stephane.remy@oncologie-pays-basque.org
Facility Name
CH de Beauvais
City
Beauvais
ZIP/Postal Code
60021
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Fayçal HOCINE, Dr
Email
f.hocine@ch-beauvais.fr ; fayoncologie@yahoo.fr
Facility Name
CH de Blois
City
Blois
ZIP/Postal Code
41000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Dany GARGOT, Dr
Email
dgargot@ch-blois.fr
Facility Name
CHU Avicenne
City
BOBIGNY cedex
ZIP/Postal Code
93009
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Thomas APARICIO, Pr
Phone
01 48 95 54 31
Email
thomas.aparicio@avc.aphp.fr
First Name & Middle Initial & Last Name & Degree
Mourad BENALLAOUA
Phone
01 48 95 54 31
Email
thomas.aparicio@avc.aphp.fr
First Name & Middle Initial & Last Name & Degree
Thomas APARICIO
First Name & Middle Initial & Last Name & Degree
Florence MARY
Facility Name
Polyclinique Bordeaux Nord
City
Bordeaux CEDEX
ZIP/Postal Code
33077
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Cédric LECAILLE, Dr
Email
lecail@hotmail.com; m.balhadere@hotmail.fr
Facility Name
Hôpital Duchenne
City
Boulogne-sur-Mer
ZIP/Postal Code
62321
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Vincent BOURGEOIS, Dr
Email
vincebourgeois@hotmail.com
Facility Name
Hôpital Pierre Oudot
City
Bourgoin-Jallieu
ZIP/Postal Code
38300
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Benoit AVISSE, Dr
Email
benoit.avisse@club-internet.fr;bavisse@ch-bourgoin.fr
Facility Name
Clinique Pasteur Saint Esprit
City
Brest
ZIP/Postal Code
29200
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Véronique JESTIN LE TALLEC, Dr
Email
veronique.jestin-letallec@orange.fr
Facility Name
CH de Béziers
City
Béziers
ZIP/Postal Code
34525
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mohamed RAMDANI, Dr
Email
mohamed.ramdani@ch-beziers.fr
Facility Name
CHU Côte de Nacre
City
Caen
ZIP/Postal Code
14033
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Karine BOUHIER LEPORRIER, Dr
Email
bouhierleporrier-k@chu-caen.fr
Facility Name
CH
City
Cahors
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Nadia LEVASSEUR
Email
nadia.levasseur@ch-cahors.fr
First Name & Middle Initial & Last Name & Degree
Nadia LEVASSEUR
Facility Name
Infirmerie Protestante de Lyon
City
Caluire-et-Cuire
ZIP/Postal Code
69300
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Johannes HARTWIG, Dr
Email
johannes.hartwig@infirmerie-protestante.com
Facility Name
CH William Morey
City
Chalon-sur-Saône
ZIP/Postal Code
71100
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Laurie RAMBACH, Dr
Email
laurie.rambach@ch-chalon71.fr
Facility Name
Hôpital Privé Sainte Marie
City
Chalon-sur-Saône
ZIP/Postal Code
71100
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Adrien MELIS, Dr
Email
melisadrien@yahoo.fr
Facility Name
Centre Hospitalier Métropole Savoie
City
Chambery CEDEX
ZIP/Postal Code
73011
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jocelyne PROVENCAL, Dr
Email
jocelyne.provencal@ch-metropole-savoie.fr
Facility Name
Centre Hospitalier Public du Cotentin
City
Cherbourg
ZIP/Postal Code
50102
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Laure KALUZINSKI, Dr
Email
recherche-clinique@ch-cotentin.fr
Facility Name
CH
City
Cherbourg
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Laure KALUZINSKI
Email
l.kaluzinski@ch-cherbourg.fr
First Name & Middle Initial & Last Name & Degree
Laure KALUZINSKI
First Name & Middle Initial & Last Name & Degree
Arm ELWESHI
First Name & Middle Initial & Last Name & Degree
Jean-Nicolas PINHO
Facility Name
Centre Hospitalier Général
City
Châlons-en-Champagne
ZIP/Postal Code
51005
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Naceur ABDELLI, Dr
Email
nabdelli@ch-chalonsenchampagne.fr; docteurnaceurabdelli@gmail.com
Facility Name
CHU Estaing
City
Clermont-Ferrand
ZIP/Postal Code
63003
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Caroline PETORIN, Dr
Email
cpetorin@chu-clermontferrand.fr
Facility Name
Hopitaux Civils de Colmar
City
Colmar
ZIP/Postal Code
68024
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Gilles BREYSACHER, Dr
Email
gilles.breysacher@ch-colmar.fr
Facility Name
Centre Hospitalier
City
Compiègne CEDEX
ZIP/Postal Code
60321
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jean-Christophe DUCHMANN, Dr
Email
jc.duchmann@ch-compiegnenoyon.fr
Facility Name
CH
City
Contamine sur Arve
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Carol ALLIOT
Email
calliot@ch-alpes-leman.fr
First Name & Middle Initial & Last Name & Degree
Carol ALLIOT
Facility Name
Centre Hospitalier Sud Francilien
City
Corbeil-Essonnes
ZIP/Postal Code
91106
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Samy LOUAFI, Dr
Email
samy.louafi@gmail.com; samy.louafi@chsf.fr
Facility Name
Clinique des Cèdres
City
Cornebarrieu
ZIP/Postal Code
31700
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Isabelle ROQUE, Dr
Email
isa.roque@wanadoo.fr
Facility Name
Clinique des Cèdres
City
Cornebarrieu
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Isabelle ROQUE
Email
isa.roque@wanadoo.fr
First Name & Middle Initial & Last Name & Degree
Isabelle ROQUE
First Name & Middle Initial & Last Name & Degree
Alain LEDIT
Facility Name
Centre Hospitalier de Dax
City
Dax CEDEX
ZIP/Postal Code
40107
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Laure GAUTIER FELIZOT, Dr
Email
gautier-felizot@ch-dax.fr
Facility Name
Service de médecine
City
Digne-les-Bains
ZIP/Postal Code
04000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Gilbert BORDES, Dr
Email
gbordes@ch-digne.fr
Facility Name
Hôpital François Mitterand
City
Dijon CEDEX
ZIP/Postal Code
21079
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Côme LEPAGE, Pr
Email
come.lepage@u-bourgogne.fr
Facility Name
Institut de Cancérologie de Bourgogne - GRRECC
City
Dijon
ZIP/Postal Code
21000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Geneviève BOILLEAU-JOLIMOY, Dr
Email
gjolimoy@icb-cancer.fr; gjolimoy@yahoo.fr
Facility Name
Centre Goerges François Leclerc
City
Dijon
ZIP/Postal Code
21079
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Leila BENGRINE LEFEVRE, Dr
Email
lbengrine@cgfl.fr
Facility Name
CHI Elbeuf-Louviers-Val de Reuil
City
Elbeuf
ZIP/Postal Code
76503
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Anne-Marie QUENIET, Dr
Email
anne-marie.queuniet@chi-elbeuf-louviers.fr
Facility Name
CH
City
Flers
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Pierre-Emmanuel HENNERESSE
Email
pierre-emmanuel.henneresse@ch-flers.fr ; netpeh@orange.fr
First Name & Middle Initial & Last Name & Degree
Pierre-Emmanuel HENNERESSE
First Name & Middle Initial & Last Name & Degree
Laurent LION
Facility Name
CHI de Fréjus Saint-Raphaël
City
Fréjus
ZIP/Postal Code
83600
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Bruno VALENZA, Dr
Email
valenza-b@chi-frejus-saint-raphael.fr;oncologie-sec@chi-fsr.fr; brunovalenza@msn.com
Facility Name
Centre médical des Forcilles
City
Férolles-Attilly
ZIP/Postal Code
77150
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hélène DALL OSTO, Dr
Email
hdallosto@cognacq-jay.fr
Facility Name
Centre Hospitalier
City
Gap
ZIP/Postal Code
05007
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Olivier GUILLEM, Dr
Email
olivier.guillem@chicas-gap.fr; olivier.guillem@gmail.com
Facility Name
Centre Hospitalier
City
Gonesse
ZIP/Postal Code
95500
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yacine HADJARAB, Mr
Email
yacine.hadjarab@wanadoo.fr
Facility Name
CH
City
Gonesse
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sabri AHMED
Facility Name
CHU de Grenoble - Hôpital A. Michallon
City
Grenoble CEDEX
ZIP/Postal Code
38043
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jean-Luc FAUCHERON, Pr
Email
jlfaucheron@chu-grenoble.fr
Facility Name
CH Marne La Vallée-Jossigny
City
Jossigny
ZIP/Postal Code
77600
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Christine LE FOLL, Dr
Email
clefoll@ch-marnelavallee.fr
Facility Name
CHD Vendée
City
La Roche-sur-Yon
ZIP/Postal Code
85925
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Roger FAROUX, Dr
Email
roger.faroux@chd-vendee.fr
Facility Name
Groupe Hospitalier de la Rochelle Ré-Aunis
City
La Rochelle
ZIP/Postal Code
17019
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Marie BRECHON, Dr
Email
marie.brechon@ch-larochelle.fr
Facility Name
CH
City
Le Coudray
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Gabriela TOSSEN
Email
gtossen@hotmail.com
First Name & Middle Initial & Last Name & Degree
Gabriela TOSSEN
First Name & Middle Initial & Last Name & Degree
Michèle MANGOLD
Facility Name
CH du Mans
City
Le Mans CEDEX 9
ZIP/Postal Code
72037
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Oana COJOCARASU, Dr
Email
ocojocarasu@ch-lemans.fr; oanaalexa@hotmail.com
Facility Name
Centre Oscar Lambret
City
Lille
ZIP/Postal Code
59037
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Farid EL HAJBI, Dr
Email
f-elhajbi@o-lambret.fr
Facility Name
CHRU Hôpital Claude Huriez 4eme EST
City
Lille
ZIP/Postal Code
59037
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Anthony TURPIN, Dr
Email
turpin.anth@yahoo.fr; anthony.turpin@chru-lille.fr
Facility Name
Clinique François Chénieux
City
Limoges
ZIP/Postal Code
87000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jean MARTIN, Dr
Email
jm@imagemed-87.com
Facility Name
CHU Dupuytren
City
Limoges
ZIP/Postal Code
87042
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Valérie LE BRUN LY, Dr
Email
valerie.lebrun@chu-limoges.fr
Facility Name
CH
City
Longjumeau
ZIP/Postal Code
91164
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Joël EZENFIS, Dr
Email
joel.ezenfis@ch-longjumeau.fr
Facility Name
CHBS - Hôpital du Scorff
City
Lorient CEDEX
ZIP/Postal Code
56322
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Joëlle EGRETEAU, Dr
Email
j.egreteau@ch-bretagne-sud.fr
Facility Name
Clinique de la Sauvegarde
City
Lyon CEDEX 09
ZIP/Postal Code
69009
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Isabelle MOULLET, Dr
Email
i.moullet@wanadoo.fr
Facility Name
Clinique Mutualiste Eugène André
City
Lyon
ZIP/Postal Code
69003
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Cécile FOURNEL, Dr
Email
cecile.fournel@icloire.fr
Facility Name
Hôpital Privé Jean Mermoz
City
Lyon
ZIP/Postal Code
69008
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jérôme DESRAME, Pr
Email
jerome.desrame@orange.fr
Facility Name
CHU de Lyon - Croix Rousse
City
Lyon
ZIP/Postal Code
69317
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Marielle GUILLET, Dr
Email
marielle.guillet@chu-lyon.fr; marielguillet@hotmail.fr; celine.leclercq@chu-lyon.fr
Facility Name
CH ST Joseph-ST Luc
City
Lyon
ZIP/Postal Code
69365
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Denis PERE VERGE, Dr
Email
dpereverge@ch-stjoseph-stluc-lyon.fr; fannydenis@sfr.fr
Facility Name
Hôpital Edouard Herriot
City
Lyon
ZIP/Postal Code
69437
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Julien FORESTIER, Dr
Email
julien.forestier@chu-lyon.fr
Facility Name
Centre Radiologie
City
Macon
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Isabelle POUCHARD
Email
rthmacon@orange.fr; iporlem@orange.fr
First Name & Middle Initial & Last Name & Degree
Isabelle POUCHARD
First Name & Middle Initial & Last Name & Degree
Fabrice LORCHEL
First Name & Middle Initial & Last Name & Degree
Nicolas BARBET
Facility Name
Hôpital Européen Marseille
City
Marseille CEDEX 03
ZIP/Postal Code
13331
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yves RINALDI, Dr
Email
y.rinaldi@hopital-europeen.fr; yrinaldi@wanadoo.fr
Facility Name
Hopital Nord
City
Marseille CEDEX 20
ZIP/Postal Code
13915
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mohamed GASMI, Dr
Email
mohamed.gasmi@ap-hm.fr
Facility Name
CHU La Timone
City
Marseille CEDEX 5
ZIP/Postal Code
13385
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Laétitia DAHAN, Pr
Email
laetitia.dahan@ap-hm.fr
Facility Name
CH de Meaux
City
Meaux
ZIP/Postal Code
77100
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Christophe LOCHER, Dr
Email
c-locher@ch-meaux.fr
Facility Name
Hôpital Layne
City
Mont-de-Marsan
ZIP/Postal Code
40024
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jérôme DAUBA, Dr
Email
jerome.dauba@ch-mt-marsan.fr
Facility Name
Hôpital Monod
City
Montivilliers
ZIP/Postal Code
76290
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Charline MARRE, Dr
Email
charline.marre@ch-havre.fr; charlinemarre@gmail.com
Facility Name
Centre Hospitalier
City
Montélimar
ZIP/Postal Code
26216
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Agnès PELAQUIER, Dr
Email
agnes.pelaquier@ch-montelimar.fr; agnes.pelaquier@free.fr
Facility Name
Centre Hospitalier
City
Morlaix CEDEX
ZIP/Postal Code
29672
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Marc FEREC, Dr
Email
mferec@ch-morlaix.fr; marc_ferec@hotmail.com
Facility Name
Centre Azuréen de Cancérologie
City
Mougins
ZIP/Postal Code
06250
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Benjamin HOCH, Dr
Email
dr.bhoch@gmail.com
Facility Name
Hôpital Privé du Confluent SAS
City
Nantes
ZIP/Postal Code
44277
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hélène CASTANIE, Dr
Email
helene.castanie@groupeconfluent.fr
Facility Name
Hôpital Américain de Paris
City
Neuilly-sur-Seine
ZIP/Postal Code
92200
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lionel VEDRINE, Pr
Email
lionelvedrine@orange.fr
Facility Name
Hôpital Pierre Bérégovoy
City
Nevers CEDEX
ZIP/Postal Code
58033
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Abdelkader OUAZIR, Dr
Email
abdelkader.ouazir@ch-nevers.fr
Facility Name
Centre Antoine Lacassagne
City
Nice CEDEX 2
ZIP/Postal Code
06189
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Eric FRANCOIS, Dr
Email
eric.francois@nice.unicancer.fr
Facility Name
Centre Oncogard
City
Nîmes CEDEX 9
ZIP/Postal Code
30029
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jacques CRETIN, Dr
Email
cretinjacques@yahoo.fr
Facility Name
CHU Carémeau
City
Nîmes
ZIP/Postal Code
30029
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Valérie PHOUTTHASANG, Dr
Email
Valivalo@hotmail.com
Facility Name
Hôpital de la Source
City
Orléans CEDEX 2
ZIP/Postal Code
45067
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jean-Paul LAGASSE, Dr
Email
jean-paul.lagasse@chr-orleans.fr
Facility Name
Hôpital Privé des Peupliers
City
Paris
ZIP/Postal Code
75013
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mustapha ZOUBIR, Dr
Email
m.zoubir@gsante.fr
Facility Name
Hôpital Saint Antoine
City
Paris
ZIP/Postal Code
75571
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Daniel LOPEZ-TRABADA, Dr
Email
daniel.lopez-trabada-ataz@aphp.fr
Facility Name
HEGP
City
Paris
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Julien TAIEB
Email
julien.taieb@egp.aphp.fr; jtaieb75@gmail.com
First Name & Middle Initial & Last Name & Degree
Julien TAIEB
First Name & Middle Initial & Last Name & Degree
Céline LEPERE
First Name & Middle Initial & Last Name & Degree
Bruno LANDI
First Name & Middle Initial & Last Name & Degree
Anne-Laure POINTET
First Name & Middle Initial & Last Name & Degree
Géraldine PERKINS
First Name & Middle Initial & Last Name & Degree
Aziz ZAANAN
First Name & Middle Initial & Last Name & Degree
Jean-Nicolas VAILLANT
First Name & Middle Initial & Last Name & Degree
Jeanne NETTER
First Name & Middle Initial & Last Name & Degree
Simon PERNOT
Facility Name
Hôpital Cochin
City
Paris
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Romain CORIAT
Email
romain.coriat@cch.aphp.fr
First Name & Middle Initial & Last Name & Degree
Romain CORIAT
First Name & Middle Initial & Last Name & Degree
Marion DHOOGE
First Name & Middle Initial & Last Name & Degree
Johann DREANIC
First Name & Middle Initial & Last Name & Degree
Jean-Marie TIGAUD
First Name & Middle Initial & Last Name & Degree
Catherine BREZAULT
Facility Name
Hôpital Saint Louis
City
Paris
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jean-Marc GORNET
Email
jean-marc.gornet@sls.aphp.fr
First Name & Middle Initial & Last Name & Degree
Jean-Marc GORNET
Facility Name
Institut Montsouris
City
Paris
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Christophe LOUVET
Email
christophe.louvet@imm.fr
First Name & Middle Initial & Last Name & Degree
Christophe LOUVET
First Name & Middle Initial & Last Name & Degree
Mostefa BENNANMOUN
First Name & Middle Initial & Last Name & Degree
Jean-Luc MOLITOR
Facility Name
Pitié Salpêtière
City
Paris
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Olivier DUBREUIL
Email
olivier.dubreuil@aphp.fr
First Name & Middle Initial & Last Name & Degree
Olivier DUBREUIL
First Name & Middle Initial & Last Name & Degree
Jean-Baptiste BACHET
First Name & Middle Initial & Last Name & Degree
Solène DOAT
Facility Name
Centre Hospitalier
City
Pau CEDEX
ZIP/Postal Code
64046
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Juliette THAURY, Dr
Email
juliette.thaury@ch-pau.fr; jthaury@yahoo.fr
Facility Name
Hôpital Haut Leveque
City
Pessac CEDEX
ZIP/Postal Code
33604
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Eric TERREBONNE, Dr
Email
eric.terrebonne@chu-bordeaux.fr
Facility Name
CHU Lyon Sud
City
Pierre-Bénite
ZIP/Postal Code
64495
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Claire FALANDRY, Dr
Email
claire.falandry@chu-lyon.fr
Facility Name
Centre CARIO - HCPA
City
Plérin
ZIP/Postal Code
22190
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Pierre-Luc ETIENNE, Dr
Email
pl.etienne@cario-sante.fr ; pl.etienne@wanadoo.fr
Facility Name
Hôpital de la Milétrie
City
Poitiers
ZIP/Postal Code
86021
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
David TOUGERON, Pr
Email
david.tougeron@chu-poitiers.fr
Facility Name
CH Annecy Genevois
City
Pringy
ZIP/Postal Code
74374
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Emmanuel MAILLARD, Dr
Email
emaillard@ch-annecygenevois.fr
Facility Name
Polyclinique Francheville
City
Périgueux
ZIP/Postal Code
24004
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Laurent CANY, Dr
Email
l.cany@oncoradio24.com
Facility Name
CHU Robert Debré
City
Reims CEDEX
ZIP/Postal Code
51092
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Olivier BOUCHE, Pr
Email
obouche@chu-reims.fr
Facility Name
CHU de Pontchaillou
City
Rennes CEDEX 9
ZIP/Postal Code
35033
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Astrid LIEVRE, Pr
Email
astrid.lievre@chu-rennes.fr
Facility Name
Centre Eugène Marquis
City
Rennes CEDEX
ZIP/Postal Code
35042
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Astrid LIEVRE, Dr
Email
astrid.lievre@chu-rennes.fr
Facility Name
CH
City
Rodez
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Laurent MOSSER
Email
l.mosser@ch-rodez.fr
First Name & Middle Initial & Last Name & Degree
Laurent MOSSER
Facility Name
Hôpital Drome Nord
City
Romans-sur-Isère
ZIP/Postal Code
26100
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Marie-Claude GOUTTEBEL, Dr
Email
mc.gouttebel@hopitaux-drome-nord.fr
Facility Name
CHU Charles Nicolle
City
Rouen CEDEX 01
ZIP/Postal Code
76031
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
David SEFRIOUI, Dr
Email
david.sefrioui@chu-rouen.fr
Facility Name
Clinique Mathilde
City
Rouen CEDEX
ZIP/Postal Code
76175
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sakher ALADEN, Dr
Facility Name
Hôpital Privé Saint Grégoire
City
Saint Gregoire
ZIP/Postal Code
35768
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Anne MERCIER BLAS, Dr
Email
amercierblas@vivalto-sante.com
Facility Name
ICO - Site René Gauducheau
City
Saint Herblain
ZIP/Postal Code
44805
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sandrine HIRET, Dr
Email
Sandrine.hiret@ico.unicancer.fr
Facility Name
Institut de Cancérologie Lucien Neuwirth
City
Saint Priest en Jarez
ZIP/Postal Code
42271
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jean-Marc PHELIP, Pr
Email
j.marc.phelip@chu-st-etienne.fr
Facility Name
CH
City
Saint Quentin
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Innocenti DADAMESSI
Email
I.dadamessi@ch-stquentin.fr;dadamessi@gmail.com
First Name & Middle Initial & Last Name & Degree
Innocenti DADAMESSI
Facility Name
Institut Curie
City
Saint-Cloud
ZIP/Postal Code
92210
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Amani ASNACIOS-LECERF, Dr
Email
amaniasnacios@yahoo.fr; amani.asnacioslecerf@curie.fr
Facility Name
Polyclinique Côte Basque Sud
City
Saint-Jean-de-Luz
ZIP/Postal Code
64500
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Etienne MAURIAC, Dr
Email
etiennemauriac@gmail.com
Facility Name
Centre Hospitalier de Saint-Malo
City
Saint-Malo
ZIP/Postal Code
35403
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Romain DESGRIPPES, Dr
Email
r.desgrippes@ch-stmalo.fr
Facility Name
Hôpital d'Instruction des Armées Begin
City
Saint-Mandé
ZIP/Postal Code
94163
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Serge CREMADES, Pr
Email
cremades.sa@club-internet.fr
Facility Name
Polyclinique Saint Claude
City
Saint-Quentin
ZIP/Postal Code
02100
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Pierre VANELSLANDER, Dr
Email
vanelspi@gmail.com
Facility Name
CH Saintonge
City
Saintes
ZIP/Postal Code
17108
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Florence BORDE-MOUGENOT, Dr
Email
3C@ch-saintonge.fr; f.borde@ch-saintonge.fr
Facility Name
CH Morlevat
City
Semur-en-Auxois
ZIP/Postal Code
21140
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Arnaud PATENOTTE, Dr
Email
arnaud.patenotte@ch-semur-en-auxois.fr
Facility Name
CH
City
Senlis CEDEX
ZIP/Postal Code
60309
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Elisabeth CAROLA, Dr
Email
elisabeth.carola@ghpso.fr
Facility Name
Centre Hospitalier
City
Sens CEDEX
ZIP/Postal Code
89108
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hélène COSME GASSMANN, Dr
Email
hcosme@ch-sens.fr
Facility Name
CH Région Saint Omer
City
St Omer
ZIP/Postal Code
62505
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Claire CAPELLE, Dr
Email
c.capelle@ch-boulogne.fr; claire.capelle@gmx.fr
Facility Name
Clinique Sainte Anne
City
Strasbourg
ZIP/Postal Code
67000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Louis-Marie DOURTHE, Dr
Email
lm.dourthe@solcrr.org
Facility Name
Centre Paul Strauss
City
Strasbourg
ZIP/Postal Code
67065
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Meher BEN ABDELGHANI, Dr
Email
mbenabdelghani@strasbourg.unicancer.fr
Facility Name
Hôpitaux du Leman
City
Thonon-les-Bains
ZIP/Postal Code
74203
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ahmed BEDJAOUI, Dr
Email
a-bedjaoui@ch-hopitauxduleman.fr
Facility Name
Hôpital Sainte Musse
City
Toulon
ZIP/Postal Code
83000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Frédéric VIRET, Dr
Email
frederic.viret@ch-toulon.fr
Facility Name
Hôpital Sainte Musse
City
Toulon
ZIP/Postal Code
83000
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Camille SIBERTIN-BLANC, Dr
Email
camille.sibertin-blanc@ch-toulon.fr
Facility Name
Clinique Saint Jean du Languedoc
City
Toulouse
ZIP/Postal Code
31077
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Etienne Suc, Dr
Email
esucsjl@club-internet.fr
Facility Name
Hôpitaux Trousseau
City
Tours CEDEX 9
ZIP/Postal Code
37044
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Thierry LECOMTE, Pr
Email
thierry.lecomte@med.univ-tours.fr
Facility Name
Centre Hospitalier
City
Valenciennes
ZIP/Postal Code
59322
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Isabelle BONNET, Dr
Email
bonnet-i@ch-valenciennes.fr
Facility Name
CHU de Nancy-Bradois
City
Vandoeuvre les nancy
ZIP/Postal Code
54511
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Anthony LOPEZ, Dr
Email
anthony-lopez@hotmail.fr; a.lopez@chru-nancy.fr
Facility Name
Institut de Cancérologie de Lorraine
City
Vandoeuvre les nancy
ZIP/Postal Code
54519
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Marie-Christine KAMINSKY, Dr
Email
mc.kaminsky@nancy.unicancer.fr
Facility Name
Paul Brousse
City
Villejuif
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Anne THIROT-BIDAULT
Email
anne.bidault@bct.aphp.fr
First Name & Middle Initial & Last Name & Degree
Anne THIROT-BIDAULT
Facility Name
Centre Hospitalier
City
Villeneuve-Saint-Georges
ZIP/Postal Code
94195
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Linda BOUAITA, Dr
Email
lindabouaita@yahoo.fr
12. IPD Sharing Statement
Citations:
PubMed Identifier
26748426
Citation
Aparicio T, Francois E, Cristol-Dalstein L, Carola E, Maillard E, Paillaud E, Retornaz F, Faroux R, Andre T, Bedenne L, Seitz JF. PRODIGE 34-FFCD 1402-ADAGE: Adjuvant chemotherapy in elderly patients with resected stage III colon cancer: A randomized phase 3 trial. Dig Liver Dis. 2016 Feb;48(2):206-7. doi: 10.1016/j.dld.2015.11.023. Epub 2015 Dec 2. No abstract available.
Results Reference
background
Learn more about this trial
Randomised Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over
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