SystemCHANGE: An Intervention for Medication Change in Adult Kidney Transplant Patients (MAGIC)
Kidney Disease
About this trial
This is an interventional treatment trial for Kidney Disease focused on measuring medication adherence, outcomes, intervention, randomized controlled trial
Eligibility Criteria
Inclusion Criteria:
- age 18 years or older,
- prescribed at least 1 immunosuppressive medication taken twice a day,
- functioning KT (not on dialysis),
- has received a kidney-only transplant,
- agreement from the transplant physician and nephrologist that individual is able to participate in the study,
- able to speak, hear, and understand English as determined by the ability to participate and comprehend conversation about potential inclusion in the study,
- able to open a MEMS cap as assessed by the Research Assistant (RA) asking if there is any problem with opening pill bottle caps,
- able to administer immunosuppressive medications to self,
- has a telephone or has access to a telephone,
- has no cognitive impairment as determined by a score of 4 or greater on the 6-item Telephone Mental Status Screen Derived from the Mini-Mental Status Exam,
- has no other diagnoses that may shorten life span, such as metastatic cancer,
- is not currently hospitalized,
- receives post-transplant care by the Missouri or Tennessee transplant programs.
Exclusion Criteria:
- None
Sites / Locations
- University of Missouri-Kansas City
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
SystemCHANGE
Patient-education attention-control
SystemCHANGE supports patient-designed, interventionist-guided, small experiments to: 1) assess individual systems (including important others who shape medication taking) and the system's impact on medication taking and propose individual system solutions to improve MA, 2) implement the proposed individual systems' solutions to improve MA, 3) track MA data, and 4) evaluate MA data.
The 6-month Patient education attention-control (AC) intervention includes 6 transplant educational materials, covering healthy post-transplant behavior, developed by the International Transplant Nurses Society. The RA calls Pps at 1, 2, 3, 4, 5 and 6 months to review the brochure information and answer any questions about it.