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A Study of Galeterone Compared to Enzalutamide In Men Expressing Androgen Receptor Splice Variant-7 mRNA (AR-V7) Metastatic CRPC (ARMOR3-SV)

Primary Purpose

Prostate Cancer

Status
Terminated
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Galeterone
Enzalutamide
Sponsored by
LTN PHARMACEUTICALS, INC.
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Prostate Cancer

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)MaleDoes not accept healthy volunteers

Inclusion Criteria:

  • Progressive metastatic (M1) disease on androgen deprivation therapy
  • Detectable AR-V7 from circulating tumors (CTCs)
  • ECOG performance status 0 or 1

Exclusion Criteria:

  • Prior treatment with second generation anti-androgens (e.g. abiraterone, enzalutamide)
  • Prior treatment with chemotherapy for CRPC

Sites / Locations

  • Pinnacle Oncology Hematology
  • University Of Arizona Cancer Center
  • City of Hope
  • USC Norris Comprehensive Cancer Center
  • UCLA Jonsson Comprehensive Cancer Center
  • Prostate Oncology Specialists, Inc.
  • UC Davis Cancer Center
  • San Bernardino Urological Associates
  • Urology Speciality Group
  • University of Colorado Cancer Center Anschultz Cancer Pavilion
  • The Urology Center of Colorado
  • Yale University School of Medicine
  • Georgetown University Medical Center
  • Sibley Memorial Hospital
  • Boca Raton Community Hospital, Inc.
  • University of Florida Health Cancer Center
  • Moffitt Cancer Center
  • First Urology
  • Tulane Medical Center
  • Regional Urology, LLC
  • University of Maryland Greenenbaum Cancer Center
  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  • Walter Reed National Military Medical Center
  • Massachusetts General Hospital
  • Dana-Farber Cancer Institute
  • Beth Israel Deaconess Medical Center
  • University of Michigan Health System
  • Karmanos Cancer Center
  • Urology Cancer Center and GU Research Network
  • Coastal Urology Associates
  • Brooklyn Urology Research Group
  • Advanced Urology Centers of New York
  • Premier Medical Group of the Hudson Valley
  • Associated Medical Professionals of NY
  • University of North Carolina Lineberger Cancer Center
  • Carolina Urology Partners, PLLC
  • Carolina Urology Partners
  • The Urology Group
  • Clinical Research Solutions
  • Oregon Urology Institute
  • Lancaster Urology
  • Fox Chase Cancer Center
  • UPMC Cancer Centers
  • Carolina Urologic Research Center
  • Urology Associates Clinical Research
  • Urology Clinics of North Texas
  • Texas Oncology/Baylor University Medical Center
  • Urology San Antonio
  • Virginia Urology
  • Urology of Virginia
  • The University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
  • St. George Private Hospital, Oncology Day Care Centre
  • Ashford Cancer Centre/Adelaide Cancer Centre Research
  • North Coast Cancer Institute
  • Prince of Wales Hospital
  • Macquarie University
  • Peninsula Specialist Centre
  • ICON Cancer Care
  • Princess Alexandra Hospital
  • Ashford Cancer Centre/Adelaide Cancer Centre Research
  • Box Hill Hospital
  • Monash Medical Centre
  • Peter MacCallum Cancer Centre
  • Cabrini Hospital
  • Jules Bordet Institute Clinique d'Oncologie Medicale
  • Universitair Ziekenhuis Gent
  • Jessa Ziekenhuis
  • CHU Sart Tilman
  • British Columbia Cancer
  • British Columbia Cancer
  • London Health Sciences Centre
  • Sunnybrook Research Institute
  • Princess Margaret Hospital
  • Centre Hospitalier De I'Universite de Montreal
  • Centre Hospitalier Universitaire de Quebec
  • Centre Paul Papin
  • Institut Sainte Catherine
  • Institut Bergonié
  • Centre François Baclesse
  • Service de Médecine Interne Onco-Hématologie
  • Clinique Victor Hugo Centre Jean Bernard
  • Centre Léon Bérard
  • Hôpital Edouard Herriot
  • Centre Antoine Lacassagne
  • Institut de Cancérologie de l'Ouest
  • Institut de Cancerlogie de la Loire
  • Centre René Gauducheau
  • Institut Gustave-Roussy
  • Centro Oncologico c/o Presidio Ospedaliero San Donato - Arezzo
  • Unità Operativa di Oncologia Ospedale Civile degli Infe
  • Romagnolo per lo Studio e la Cura dei Tumori IRST-IRCCS - Oncologia medica
  • AOU "S. Luigi", SCDU Oncologia Medica
  • Az. Ospedaliera San Camillo-Forlanini
  • University of Turin
  • Santa Chiara Hospital
  • Hospital Clínic i Provincial de Barcelona-Oncology
  • Instituto Catalan de Oncologia (Hospital Durans i Reynals)
  • Hospital General Universitario de Elche
  • Hospital General Universitario Gregorio Marañón
  • Spanish National Cancer Research Centre
  • Unidad Cnio Ibima de Investigacion en Prostata
  • Fundación Althaia Manresa
  • Hospital Son Espases - Oncología
  • Hospital Clinico Universitario de Navarra
  • Consorci Hospitalari de Parc Taulí
  • Hospital Universitario Virgen del Rocio
  • IVO-Oncología Médica
  • CR-UK Institute for Cancer Studies
  • Sussex Cancer Centre
  • University College of London Hospitals
  • Guy's and St. Thomas' NHS Foundation Trust
  • Southampton General Hospital
  • University of Surrey Post Graduate Medical Hospital
  • Royal Marsden Hospital
  • The Royal Cornwall Hospital
  • The Beatson West of Scotland Cancer Centre
  • Velindre Hospital

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

Galeterone

Enzalutamide

Arm Description

Outcomes

Primary Outcome Measures

Radiographic Progression-free survival

Secondary Outcome Measures

Overall Survival
Time to Initiation of Cytotoxic Chemotherapy

Full Information

First Posted
March 19, 2015
Last Updated
March 13, 2023
Sponsor
LTN PHARMACEUTICALS, INC.
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1. Study Identification

Unique Protocol Identification Number
NCT02438007
Brief Title
A Study of Galeterone Compared to Enzalutamide In Men Expressing Androgen Receptor Splice Variant-7 mRNA (AR-V7) Metastatic CRPC
Acronym
ARMOR3-SV
Official Title
ARMOR3-SV: A Phase 3, Randomized, Open Label, Multi-Center, Controlled Study of Galeterone Compared to Enzalutamide in Men Expressing Androgen Receptor Splice Variant-7 mRNA (AR-V7) Metastatic (M1) Castrate Resistant Prostate Cancer (CRPC)
Study Type
Interventional

2. Study Status

Record Verification Date
September 2017
Overall Recruitment Status
Terminated
Study Start Date
June 2015 (undefined)
Primary Completion Date
July 2016 (Actual)
Study Completion Date
November 2016 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
LTN PHARMACEUTICALS, INC.

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The purpose of this study is to compare galeterone to enzalutamide in men expressing androgen receptor spice variant-7 mRNA (AR-V7) in metastatic (M1) castrate resistant prostate cancer (CRPC).

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Prostate Cancer

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
953 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Galeterone
Arm Type
Experimental
Arm Title
Enzalutamide
Arm Type
Active Comparator
Intervention Type
Drug
Intervention Name(s)
Galeterone
Other Intervention Name(s)
TOK-001
Intervention Description
2550 mg galeterone tablets once daily PO
Intervention Type
Drug
Intervention Name(s)
Enzalutamide
Other Intervention Name(s)
Xtandi®
Intervention Description
160 mg enzalutamide capsules once daily PO
Primary Outcome Measure Information:
Title
Radiographic Progression-free survival
Time Frame
≥ 8 months
Secondary Outcome Measure Information:
Title
Overall Survival
Time Frame
≥ 8 months
Title
Time to Initiation of Cytotoxic Chemotherapy
Time Frame
≥ 8 months
Other Pre-specified Outcome Measures:
Title
Skeletal-related Events
Time Frame
≥ 8 months
Title
Safety measured by clinical safety laboratories and adverse events
Time Frame
≥ 8 months
Title
Prostate Specific Antigen (PSA) Response ≥ 50%
Time Frame
≥ 8 months
Title
Time to PSA progression
Time Frame
≥ 8 months
Title
Time to ECOG deterioration
Time Frame
≥ 8 months
Title
Best Overall Response by RECIST 1.1
Time Frame
≥ 8 months

10. Eligibility

Sex
Male
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Progressive metastatic (M1) disease on androgen deprivation therapy Detectable AR-V7 from circulating tumors (CTCs) ECOG performance status 0 or 1 Exclusion Criteria: Prior treatment with second generation anti-androgens (e.g. abiraterone, enzalutamide) Prior treatment with chemotherapy for CRPC
Facility Information:
Facility Name
Pinnacle Oncology Hematology
City
Scottsdale
State/Province
Arizona
ZIP/Postal Code
85258
Country
United States
Facility Name
University Of Arizona Cancer Center
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85724
Country
United States
Facility Name
City of Hope
City
Duarte
State/Province
California
ZIP/Postal Code
91010
Country
United States
Facility Name
USC Norris Comprehensive Cancer Center
City
Los Angeles
State/Province
California
ZIP/Postal Code
90033
Country
United States
Facility Name
UCLA Jonsson Comprehensive Cancer Center
City
Los Angeles
State/Province
California
ZIP/Postal Code
90095
Country
United States
Facility Name
Prostate Oncology Specialists, Inc.
City
Marina Del Rey
State/Province
California
ZIP/Postal Code
90292
Country
United States
Facility Name
UC Davis Cancer Center
City
Sacramento
State/Province
California
ZIP/Postal Code
95817
Country
United States
Facility Name
San Bernardino Urological Associates
City
San Bernardino
State/Province
California
ZIP/Postal Code
92404
Country
United States
Facility Name
Urology Speciality Group
City
Torrance
State/Province
California
ZIP/Postal Code
90505
Country
United States
Facility Name
University of Colorado Cancer Center Anschultz Cancer Pavilion
City
Aurora
State/Province
Colorado
ZIP/Postal Code
80045
Country
United States
Facility Name
The Urology Center of Colorado
City
Denver
State/Province
Colorado
ZIP/Postal Code
80211
Country
United States
Facility Name
Yale University School of Medicine
City
New Haven
State/Province
Connecticut
ZIP/Postal Code
06510
Country
United States
Facility Name
Georgetown University Medical Center
City
Washington
State/Province
District of Columbia
ZIP/Postal Code
20007
Country
United States
Facility Name
Sibley Memorial Hospital
City
Washington
State/Province
District of Columbia
ZIP/Postal Code
20016
Country
United States
Facility Name
Boca Raton Community Hospital, Inc.
City
Boca Raton
State/Province
Florida
ZIP/Postal Code
33486
Country
United States
Facility Name
University of Florida Health Cancer Center
City
Orlando
State/Province
Florida
ZIP/Postal Code
32806
Country
United States
Facility Name
Moffitt Cancer Center
City
Tampa
State/Province
Florida
ZIP/Postal Code
33612
Country
United States
Facility Name
First Urology
City
Jeffersonville
State/Province
Indiana
ZIP/Postal Code
47130
Country
United States
Facility Name
Tulane Medical Center
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70115
Country
United States
Facility Name
Regional Urology, LLC
City
Shreveport
State/Province
Louisiana
ZIP/Postal Code
71106
Country
United States
Facility Name
University of Maryland Greenenbaum Cancer Center
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21201
Country
United States
Facility Name
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21205
Country
United States
Facility Name
Walter Reed National Military Medical Center
City
Bethesda
State/Province
Maryland
ZIP/Postal Code
20307
Country
United States
Facility Name
Massachusetts General Hospital
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02114
Country
United States
Facility Name
Dana-Farber Cancer Institute
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02115
Country
United States
Facility Name
Beth Israel Deaconess Medical Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02215
Country
United States
Facility Name
University of Michigan Health System
City
Ann Arbor
State/Province
Michigan
ZIP/Postal Code
48109
Country
United States
Facility Name
Karmanos Cancer Center
City
Detroit
State/Province
Michigan
ZIP/Postal Code
48201
Country
United States
Facility Name
Urology Cancer Center and GU Research Network
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68130
Country
United States
Facility Name
Coastal Urology Associates
City
Brick
State/Province
New Jersey
ZIP/Postal Code
08724
Country
United States
Facility Name
Brooklyn Urology Research Group
City
Brooklyn
State/Province
New York
ZIP/Postal Code
11215
Country
United States
Facility Name
Advanced Urology Centers of New York
City
Plainview
State/Province
New York
ZIP/Postal Code
11803
Country
United States
Facility Name
Premier Medical Group of the Hudson Valley
City
Poughkeepsie
State/Province
New York
ZIP/Postal Code
12601
Country
United States
Facility Name
Associated Medical Professionals of NY
City
Syracuse
State/Province
New York
ZIP/Postal Code
13210
Country
United States
Facility Name
University of North Carolina Lineberger Cancer Center
City
Chapel Hill
State/Province
North Carolina
ZIP/Postal Code
27599
Country
United States
Facility Name
Carolina Urology Partners, PLLC
City
Charlotte
State/Province
North Carolina
ZIP/Postal Code
28277
Country
United States
Facility Name
Carolina Urology Partners
City
Concord
State/Province
North Carolina
ZIP/Postal Code
28025
Country
United States
Facility Name
The Urology Group
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45212
Country
United States
Facility Name
Clinical Research Solutions
City
Middleburg Heights
State/Province
Ohio
ZIP/Postal Code
44130
Country
United States
Facility Name
Oregon Urology Institute
City
Springfield
State/Province
Oregon
ZIP/Postal Code
97477
Country
United States
Facility Name
Lancaster Urology
City
Lancaster
State/Province
Pennsylvania
ZIP/Postal Code
17604
Country
United States
Facility Name
Fox Chase Cancer Center
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19111
Country
United States
Facility Name
UPMC Cancer Centers
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15232
Country
United States
Facility Name
Carolina Urologic Research Center
City
Myrtle Beach
State/Province
South Carolina
ZIP/Postal Code
29572
Country
United States
Facility Name
Urology Associates Clinical Research
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37209
Country
United States
Facility Name
Urology Clinics of North Texas
City
Dallas
State/Province
Texas
ZIP/Postal Code
75231
Country
United States
Facility Name
Texas Oncology/Baylor University Medical Center
City
Dallas
State/Province
Texas
ZIP/Postal Code
75246
Country
United States
Facility Name
Urology San Antonio
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Facility Name
Virginia Urology
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23235
Country
United States
Facility Name
Urology of Virginia
City
Virginia Beach
State/Province
Virginia
ZIP/Postal Code
23462
Country
United States
Facility Name
The University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
City
Madison
State/Province
Wisconsin
ZIP/Postal Code
53792
Country
United States
Facility Name
St. George Private Hospital, Oncology Day Care Centre
City
Kogarah
State/Province
New South Wales
ZIP/Postal Code
2217
Country
Australia
Facility Name
Ashford Cancer Centre/Adelaide Cancer Centre Research
City
Kurralta Park
State/Province
New South Wales
ZIP/Postal Code
5037
Country
Australia
Facility Name
North Coast Cancer Institute
City
Port Macquarie
State/Province
New South Wales
ZIP/Postal Code
2444
Country
Australia
Facility Name
Prince of Wales Hospital
City
Randwick
State/Province
New South Wales
ZIP/Postal Code
2031
Country
Australia
Facility Name
Macquarie University
City
Sydney
State/Province
New South Wales
ZIP/Postal Code
2109
Country
Australia
Facility Name
Peninsula Specialist Centre
City
Kippa-Ring
State/Province
Queensland
ZIP/Postal Code
4102
Country
Australia
Facility Name
ICON Cancer Care
City
Southport
State/Province
Queensland
ZIP/Postal Code
4215
Country
Australia
Facility Name
Princess Alexandra Hospital
City
Woolloongabba
State/Province
Queensland
ZIP/Postal Code
4102
Country
Australia
Facility Name
Ashford Cancer Centre/Adelaide Cancer Centre Research
City
Kurralta Park
State/Province
South Australia
ZIP/Postal Code
5037
Country
Australia
Facility Name
Box Hill Hospital
City
Box Hill
State/Province
Victoria
ZIP/Postal Code
3128
Country
Australia
Facility Name
Monash Medical Centre
City
East Bentleigh
State/Province
Victoria
ZIP/Postal Code
3165
Country
Australia
Facility Name
Peter MacCallum Cancer Centre
City
East Melbourne
State/Province
Victoria
ZIP/Postal Code
3002
Country
Australia
Facility Name
Cabrini Hospital
City
Malvern
State/Province
Victoria
ZIP/Postal Code
3144
Country
Australia
Facility Name
Jules Bordet Institute Clinique d'Oncologie Medicale
City
Brussels
ZIP/Postal Code
B-1000
Country
Belgium
Facility Name
Universitair Ziekenhuis Gent
City
Gent
ZIP/Postal Code
B-9000
Country
Belgium
Facility Name
Jessa Ziekenhuis
City
Hasselt
ZIP/Postal Code
B-3500
Country
Belgium
Facility Name
CHU Sart Tilman
City
Liège
ZIP/Postal Code
4000
Country
Belgium
Facility Name
British Columbia Cancer
City
Kelowna
State/Province
British Columbia
ZIP/Postal Code
V1Y 5L3
Country
Canada
Facility Name
British Columbia Cancer
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z 4E6
Country
Canada
Facility Name
London Health Sciences Centre
City
London
State/Province
Ontario
ZIP/Postal Code
N6A 4L6
Country
Canada
Facility Name
Sunnybrook Research Institute
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M4N 3M5
Country
Canada
Facility Name
Princess Margaret Hospital
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5G 2M9
Country
Canada
Facility Name
Centre Hospitalier De I'Universite de Montreal
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2L 4M1
Country
Canada
Facility Name
Centre Hospitalier Universitaire de Quebec
City
Quebec City
State/Province
Quebec
ZIP/Postal Code
G1R 3S1
Country
Canada
Facility Name
Centre Paul Papin
City
Angers Cedex 9
ZIP/Postal Code
49055
Country
France
Facility Name
Institut Sainte Catherine
City
Avignon
ZIP/Postal Code
84918
Country
France
Facility Name
Institut Bergonié
City
Bordeaux
ZIP/Postal Code
33076
Country
France
Facility Name
Centre François Baclesse
City
Caen Cedex
ZIP/Postal Code
14076
Country
France
Facility Name
Service de Médecine Interne Onco-Hématologie
City
La Roche Sur Yon Cedex 9
ZIP/Postal Code
85925
Country
France
Facility Name
Clinique Victor Hugo Centre Jean Bernard
City
Le Mans
ZIP/Postal Code
72000
Country
France
Facility Name
Centre Léon Bérard
City
Lyon
ZIP/Postal Code
69008
Country
France
Facility Name
Hôpital Edouard Herriot
City
Lyon
ZIP/Postal Code
Cedex 03
Country
France
Facility Name
Centre Antoine Lacassagne
City
Nice Cedex 2
ZIP/Postal Code
06189
Country
France
Facility Name
Institut de Cancérologie de l'Ouest
City
Saint Herblain
ZIP/Postal Code
44805
Country
France
Facility Name
Institut de Cancerlogie de la Loire
City
Saint Priest en Jarez
ZIP/Postal Code
42271
Country
France
Facility Name
Centre René Gauducheau
City
Saint-Herblain
ZIP/Postal Code
44805
Country
France
Facility Name
Institut Gustave-Roussy
City
Villejuif
ZIP/Postal Code
94805
Country
France
Facility Name
Centro Oncologico c/o Presidio Ospedaliero San Donato - Arezzo
City
Arezzo
ZIP/Postal Code
52100
Country
Italy
Facility Name
Unità Operativa di Oncologia Ospedale Civile degli Infe
City
Faenza (RA)
ZIP/Postal Code
48018
Country
Italy
Facility Name
Romagnolo per lo Studio e la Cura dei Tumori IRST-IRCCS - Oncologia medica
City
Meldola (FC)
ZIP/Postal Code
47014
Country
Italy
Facility Name
AOU "S. Luigi", SCDU Oncologia Medica
City
Orbassano (Torino)
ZIP/Postal Code
10043
Country
Italy
Facility Name
Az. Ospedaliera San Camillo-Forlanini
City
Roma
ZIP/Postal Code
00152
Country
Italy
Facility Name
University of Turin
City
Torino
ZIP/Postal Code
10126
Country
Italy
Facility Name
Santa Chiara Hospital
City
Trento
ZIP/Postal Code
38122
Country
Italy
Facility Name
Hospital Clínic i Provincial de Barcelona-Oncology
City
Barcelona
ZIP/Postal Code
08036
Country
Spain
Facility Name
Instituto Catalan de Oncologia (Hospital Durans i Reynals)
City
Barcelona
ZIP/Postal Code
08908
Country
Spain
Facility Name
Hospital General Universitario de Elche
City
Elche
ZIP/Postal Code
3203
Country
Spain
Facility Name
Hospital General Universitario Gregorio Marañón
City
Madrid
ZIP/Postal Code
28009
Country
Spain
Facility Name
Spanish National Cancer Research Centre
City
Madrid
ZIP/Postal Code
28050
Country
Spain
Facility Name
Unidad Cnio Ibima de Investigacion en Prostata
City
Malaga
Country
Spain
Facility Name
Fundación Althaia Manresa
City
Manresa
ZIP/Postal Code
08243
Country
Spain
Facility Name
Hospital Son Espases - Oncología
City
Palma de Mallorca
ZIP/Postal Code
07010
Country
Spain
Facility Name
Hospital Clinico Universitario de Navarra
City
Pamplona
ZIP/Postal Code
31008
Country
Spain
Facility Name
Consorci Hospitalari de Parc Taulí
City
Sabadell
ZIP/Postal Code
08208
Country
Spain
Facility Name
Hospital Universitario Virgen del Rocio
City
Sevilla
ZIP/Postal Code
41013
Country
Spain
Facility Name
IVO-Oncología Médica
City
Valencia
ZIP/Postal Code
46009
Country
Spain
Facility Name
CR-UK Institute for Cancer Studies
City
Birmingham
State/Province
England
ZIP/Postal Code
B15 2PR
Country
United Kingdom
Facility Name
Sussex Cancer Centre
City
Brighton
State/Province
England
ZIP/Postal Code
BN2 5BE
Country
United Kingdom
Facility Name
University College of London Hospitals
City
London
State/Province
England
ZIP/Postal Code
NWI 2PG
Country
United Kingdom
Facility Name
Guy's and St. Thomas' NHS Foundation Trust
City
London
State/Province
England
ZIP/Postal Code
SE1 9RT
Country
United Kingdom
Facility Name
Southampton General Hospital
City
Southampton
State/Province
England
ZIP/Postal Code
SO16 6YD
Country
United Kingdom
Facility Name
University of Surrey Post Graduate Medical Hospital
City
Surrey
State/Province
England
ZIP/Postal Code
GU2 7WG
Country
United Kingdom
Facility Name
Royal Marsden Hospital
City
Surrey
State/Province
England
ZIP/Postal Code
SM2 5PT
Country
United Kingdom
Facility Name
The Royal Cornwall Hospital
City
Truro
State/Province
England
ZIP/Postal Code
TR1 3LJ
Country
United Kingdom
Facility Name
The Beatson West of Scotland Cancer Centre
City
Glasgow
State/Province
Scotland
ZIP/Postal Code
G12 0YN
Country
United Kingdom
Facility Name
Velindre Hospital
City
Cardiff
State/Province
Wales
ZIP/Postal Code
CF14 2TL
Country
United Kingdom

12. IPD Sharing Statement

Citations:
PubMed Identifier
26908063
Citation
Aragon-Ching JB. The promising role of poly(ADP-ribose) polymerase inhibitors in prostate cancer. Asian J Androl. 2016 Jul-Aug;18(4):592-3. doi: 10.4103/1008-682X.172821.
Results Reference
derived

Learn more about this trial

A Study of Galeterone Compared to Enzalutamide In Men Expressing Androgen Receptor Splice Variant-7 mRNA (AR-V7) Metastatic CRPC

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