Comparison of the Effects of Gelatine Versus Balanced Crystalloid Solution for Volume Therapy (Gelaring)
Hemorrhage, Surgical, Hip Replacement, Total, Thrombocytopathy
About this trial
This is an interventional treatment trial for Hemorrhage, Surgical focused on measuring Hip Replacement, Total, Gelatine solution, Balanced Crystaloid Solution, Volume therapy, Platelet aggregation
Eligibility Criteria
Inclusion Criteria:
- patient scheduled for elective hip replacement surgery
- age between 19-85 years
- signed informed consent
Exclusion Criteria:
- informed consent not signed
- traumatic hip fracture
- anemia (hemoglobin level < 100 g/l)
- allergy to study drug and/or multiple allergies
- chronic heart failure with LVEF < 30%
- shock states
- coagulopathy
- thrombocytopenia
- thrombocytopathy
- chronic kidney disease with oliguria
- chronic antiplatelet drug medications
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Gelatine solution
Balanced Crystaloid solution
Gelofusine will be administrated like "fluid challenge" - 250ml of solution will be infused within 5 minutes in case of hypotension ( mean arterial pressure - MAP below 65 mmHg or below 70mmHg in patient with chronic hypertension disease). The blood pressure and heart rate before and after fluid challenge will be recorded.
Ringerfundin will be administrated like "fluid challenge" - 250ml of solution will be infused within 5 minutes in case of hypotension ( mean arterial pressure - MAP below 65 mmHg or below 70mmHg in patient with chronic hypertension disease). The blood pressure and heart rate before and after fluid challenge will be recorded.