The Effect of no Muscle Relaxant Versus Reduced-dose Rocuronium on Anesthesia in Adenotonsillectomy
Muscle Relaxants
About this trial
This is an interventional supportive care trial for Muscle Relaxants focused on measuring no muscle relaxant, rocuronium, intubation condition, tracheal intubation, operating room time, low-dose rocuronium
Eligibility Criteria
Inclusion Criteria:
- American Society of Anesthesiologist[ASA] class 1-2
- scheduled adenotonsillectomy
- written informed consent
Exclusion Criteria:
- allergy of opioids, neuromuscular blocking drugs or other medications used during general anesthesia
- known or suspected upper respiratory infection
- disorder affecting neuromuscular blockade
- suspected difficult tracheal intubation
- Developmental Disability
- known or suspected psychologic disorder
- medication (psychoactive drugs)
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Placebo Comparator
R 0.15 group
R 0.3 group
S group
Rocuronium bromide 0.15 mg kg-1 group Anesthesia was induced with propofol 2.5 mg kg-1 , fentanyl 2 mcg kg-1, and rocuronium bromide 0.15 mg kg-1 After mask ventilation with 5 vol% sevoflurane in 100% oxygen for 2 minutes, tracheal intubation was done. At the end of surgery, discontinuation of sevoflurane and extubation, sending recovery room. When poor intubating condition., added rocuronium bromide 0.3 mg kg-1 . Drug: Rocuronium bromide Rocuronium bromide 0.15 mg kg-1 was injected at I.V. line to patients (R 0.15 group), as muscle relaxants during anesthesia for adenotonsillectomy.
Rocuronium bromide 0.3 mg kg-1 group Anesthesia was induced with propofol 2.5 mg kg-1 , fentanyl 2 mcg kg-1, and rocuronium bromide 0.3 mg kg-1 After mask ventilation with 5 vol% sevoflurane in 100% oxygen for 2 minutes, tracheal intubation was done. At the end of surgery, discontinuation of sevoflurane and extubation, sending recovery room. When poor intubating condition., added rocuronium bromide 0.3 mg kg-1 . Drug: Rocuronium bromide Rocuronium bromide 0.3 mg kg-1 was injected at I.V. line to patients (R 0.3 group), as muscle relaxants during anesthesia for adenotonsillectomy.
saline Anesthesia was induced with propofol 2.5 mg kg-1 , fentanyl 2 mcg kg-1, and saline. After mask ventilation with 5 vol% sevoflurane in 100% oxygen for 2 minutes, tracheal intubation was done. At the end of surgery, discontinuation of sevoflurane and extubation, sending recovery room. When poor intubating condition., added rocuronium bromide0.3 mg kg-1 .