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A Community-based Depression Screening Intervention for Middle-aged Suicide

Primary Purpose

Suicide

Status
Completed
Phase
Not Applicable
Locations
Japan
Study Type
Interventional
Intervention
Multi-level suicide prevention programs
Suicide prevention program as usual
Sponsored by
Aomori University of Health and Welfare
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional prevention trial for Suicide focused on measuring suicide, prevention

Eligibility Criteria

36 Years - 64 Years (Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • A municipal area located in the following 4 Aomori Second Medical Zones: Hachinohe, Kamitosan, Aomori, and Tsugaru.
  • A municipal area with the higher suicide rate than the prefectural average.
  • A municipal area having the sufficient and coverable size to serve the intervention (population 10,000-99,999).

Exclusion Criteria:

  • A municipal area receiving further intervention including a depression screening for middle-aged adults.

Sites / Locations

  • Control group
  • Intervention group
  • Intervention group
  • Intervention group
  • Control group
  • Intervention group
  • Intervention group
  • Control group
  • Control group
  • Control group
  • Control group

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

Multi-level suicide prevention programs

Community intervention as usual

Arm Description

The study team, including staff members from the intervention municipalities, provided each municipality with a standardized form of the work plan used in our study. The intervention municipality autonomously conducted the intervention program during the implementation period.

Suicide prevention program as usual

Outcomes

Primary Outcome Measures

Change in suicide rates among adults aged 40-64 years between the 4-year pre- and implementation periods.

Secondary Outcome Measures

Invitation rate in the screening component
Participation rate in the screening component

Full Information

First Posted
June 3, 2015
Last Updated
June 9, 2015
Sponsor
Aomori University of Health and Welfare
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1. Study Identification

Unique Protocol Identification Number
NCT02468466
Brief Title
A Community-based Depression Screening Intervention for Middle-aged Suicide
Official Title
Impact of a Community-based Screening and Educational Intervention for Depression on Suicide Rates Among Japanese Middle-aged Adults
Study Type
Interventional

2. Study Status

Record Verification Date
June 2015
Overall Recruitment Status
Completed
Study Start Date
January 2005 (undefined)
Primary Completion Date
December 2012 (Actual)
Study Completion Date
December 2012 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Aomori University of Health and Welfare

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The purpose of this study is to examine the effectiveness of a community-based depression-screening program for suicide prevention among middle-aged adults, the investigators conducted a quasi-experimental intervention study, using a parallel cluster design with communities at municipal level as the unit of allocation and individuals as the unit of analysis.
Detailed Description
Suicide is a major cause of premature death, particularly among middle-aged adults, in the majority of Western and Asian countries. A strong association of suicide and depression often indicates the necessity of a high-risk approach for suicide prevention. Improvements in identification and treatment can lead to better depression outcomes and suicide prevention. The investigators hypothesize that a 4-year community-based intervention, consisting of universal depression screening and subsequent care support in the target areas and health education programs, would result in reduced suicide rates among the middle-aged adult population in areas with a high suicide rate.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Suicide
Keywords
suicide, prevention

7. Study Design

Primary Purpose
Prevention
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
89700 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Multi-level suicide prevention programs
Arm Type
Experimental
Arm Description
The study team, including staff members from the intervention municipalities, provided each municipality with a standardized form of the work plan used in our study. The intervention municipality autonomously conducted the intervention program during the implementation period.
Arm Title
Community intervention as usual
Arm Type
Active Comparator
Arm Description
Suicide prevention program as usual
Intervention Type
Behavioral
Intervention Name(s)
Multi-level suicide prevention programs
Intervention Description
The intervention included both screening and educational components. The screening component invited residents aged 36-64 years to participate in a two-step screening program. In the initial screening, a self-report questionnaire were mailed to all of those residents in the priority districts with a past high suicide rate. The second stage was conducted for the participants who screened positive though a semi-structural interview. Based on the results, participants who were diagnosed with a major depressive episode were provided with a referral to a psychiatry and support for treatment adherence. Written feedback on the screening results was mailed to all respondents. The educational component was implemented through workshops open to the general public (3 times every year) and local public newsletters (twice every year) designed to improve access and adherence to treatment and to reduce stigma associated with suicide and depression.
Intervention Type
Behavioral
Intervention Name(s)
Suicide prevention program as usual
Intervention Description
Usual mental health program (not including depression screening among middle-aged)
Primary Outcome Measure Information:
Title
Change in suicide rates among adults aged 40-64 years between the 4-year pre- and implementation periods.
Time Frame
4 years pre versus 4 years post
Secondary Outcome Measure Information:
Title
Invitation rate in the screening component
Time Frame
4 years post
Title
Participation rate in the screening component
Time Frame
4 years post

10. Eligibility

Sex
All
Minimum Age & Unit of Time
36 Years
Maximum Age & Unit of Time
64 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: A municipal area located in the following 4 Aomori Second Medical Zones: Hachinohe, Kamitosan, Aomori, and Tsugaru. A municipal area with the higher suicide rate than the prefectural average. A municipal area having the sufficient and coverable size to serve the intervention (population 10,000-99,999). Exclusion Criteria: A municipal area receiving further intervention including a depression screening for middle-aged adults.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Hirofumi Oyama, MD, PhD
Organizational Affiliation
Aomori University of Health and Welfare
Official's Role
Study Director
Facility Information:
Facility Name
Control group
City
Fujisaki
State/Province
Aomori
Country
Japan
Facility Name
Intervention group
City
Gonohe
State/Province
Aomori
Country
Japan
Facility Name
Intervention group
City
Hashikami
State/Province
Aomori
Country
Japan
Facility Name
Intervention group
City
Hirakawa
State/Province
Aomori
Country
Japan
Facility Name
Control group
City
Hiranai
State/Province
Aomori
Country
Japan
Facility Name
Intervention group
City
Nanbu
State/Province
Aomori
Country
Japan
Facility Name
Intervention group
City
Oirase
State/Province
Aomori
Country
Japan
Facility Name
Control group
City
Owani
State/Province
Aomori
Country
Japan
Facility Name
Control group
City
Rokunohe
State/Province
Aomori
Country
Japan
Facility Name
Control group
City
Tohoku
State/Province
Aomori
Country
Japan
Facility Name
Control group
City
Towada
State/Province
Aomori
Country
Japan

12. IPD Sharing Statement

Citations:
PubMed Identifier
24647214
Citation
Oyama H, Sakashita T. Effects of universal screening for depression among middle-aged adults in a community with a high suicide rate. J Nerv Ment Dis. 2014 Apr;202(4):280-6. doi: 10.1097/NMD.0000000000000119.
Results Reference
background
PubMed Identifier
23824236
Citation
Oyama H, Sakashita T. Differences in specific depressive symptoms among community-dwelling middle-aged Japanese adults before and after a universal screening intervention. Soc Psychiatry Psychiatr Epidemiol. 2014 Feb;49(2):251-8. doi: 10.1007/s00127-013-0735-6. Epub 2013 Jul 4.
Results Reference
background

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A Community-based Depression Screening Intervention for Middle-aged Suicide

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