Irradiated Blood Versus Non Irradiated Blood Transfusions in Craniosynostosis Repair
Graft Versus Host Disease, Hyperkalemia, Craniectomy
About this trial
This is an interventional prevention trial for Graft Versus Host Disease focused on measuring Irradiated Blood, Non-Irradiated Blood, graft versus host disease, TA-GVHD, potassium, Blood transfusion
Eligibility Criteria
Inclusion Criteria:
- Must be between 2-6 m/o
- Must be undergoing a craniosynostosis repair
- Must require a blood transfusion
Exclusion Criteria:
- n/a
Sites / Locations
- Phoenix Children's Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Patients under 4 months Receive Irradiated Blood
Patients Over 4 Months Recieve Non-Irradiated Blood
Patients under 4 months of age will receive irradiated blood products, as per hospital protocol. The patient's extracellular potassium levels will be recorded pre-transfusion, at 30 minute intervals during the transfusion, and post-transfusion. The collected data will be compared to test for correlation between extracellular potassium levels, the type of blood transfused, and the amount of calcium that is administered.
Patients over 4 months of age will receive non-irradiated blood products. The patient's extracellular potassium levels will be recorded pre-transfusion, at 30 minute intervals during the transfusion, and post-transfusion. The collected data will be compared to test for correlation between extracellular potassium levels, the type of blood transfused, and the amount of calcium that is administered.