search
Back to results

Exercise Intensity and Appetite in Adolescents

Primary Purpose

Pediatric Obesity

Status
Unknown status
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
acute exercise
Sponsored by
Université Blaise Pascal, Clermont-Ferrand
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional basic science trial for Pediatric Obesity

Eligibility Criteria

12 Years - 15 Years (Child)MaleAccepts Healthy Volunteers

Inclusion Criteria:

  • 12 to 15 years old adolescents
  • Obese according to international values for BMI
  • Being registered to the national social security insurance
  • no eating disorders
  • no medications
  • metabolic disorders

Exclusion Criteria:

  • metabolic disorders
  • food disorders
  • physical disability

Sites / Locations

    Arms of the Study

    Arm 1

    Arm 2

    Arm Type

    Experimental

    Experimental

    Arm Label

    Lean adolescents

    Obese adolescents

    Arm Description

    15 lean adolescents (BMI Under the national cut-offs for obesity), 12-15 years old, males, will be recruited

    15 obese adolescents (BMI above the national cut-offs for obesity), 12-15 years old, males, will be recruited

    Outcomes

    Primary Outcome Measures

    energy intake in kcal
    buffet meal

    Secondary Outcome Measures

    Full Information

    First Posted
    June 19, 2015
    Last Updated
    May 10, 2016
    Sponsor
    Université Blaise Pascal, Clermont-Ferrand
    search

    1. Study Identification

    Unique Protocol Identification Number
    NCT02484612
    Brief Title
    Exercise Intensity and Appetite in Adolescents
    Official Title
    Effect of Acute Exercise Intensity on Energy Intake in Adolescents: Effect of Weight Status
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    May 2016
    Overall Recruitment Status
    Unknown status
    Study Start Date
    September 2016 (undefined)
    Primary Completion Date
    December 2017 (Anticipated)
    Study Completion Date
    December 2017 (Anticipated)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Principal Investigator
    Name of the Sponsor
    Université Blaise Pascal, Clermont-Ferrand

    4. Oversight

    Data Monitoring Committee
    No

    5. Study Description

    Brief Summary
    Acute exercise has been shown to affect subsequent energy intake in obese adolescents. Indeed, it has been shown several times that an intensive bout of exercise (above 70% of the individual maximal capacities) can reduce energy intake at the following meal in obese adolescents, with no modification of his appetite feelings. Although this results has been replicated several times, it remains unknown if those nutritional adaptations are due to post-exercise modifications of some gastro-peptides implicated in appetite control, as detailed in adults. The aim of this work is to question whether or not post-exercise energy intake is explained by appetite-regulating hormones that are affected by the exercise bout in both lean and obese youth.
    Detailed Description
    After an first medical visit to ensure that the adolescents have the ability to complete the whole study, the participants will have to complete several clinical examinations: anthropometric measurements Body composition assessed by dual energy x-ray absorptiometry Maximal aerobic test They will then randomly complete the following conditions: CON: a control day without exercise; HIE: an exercise day with an exercise set at 75% of the capacities LIE: an exercise day with an exercise set at 40% of the capacities The exercises or the rest condition will be done by the end of the morning and a buffet meal will be proposed during which the participants will be asked to eat as much as wanted. Blood samples will be drawn before, after, 15 after and 30 minutes after the exercise to assess the main appetite regulating hormones involved in appetite regulation (PYY, Cholecystokinin ...) appetite feelings will be assessed throughout the day at regular interval using visual analogue scales.

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Pediatric Obesity

    7. Study Design

    Primary Purpose
    Basic Science
    Study Phase
    Not Applicable
    Interventional Study Model
    Factorial Assignment
    Masking
    None (Open Label)
    Allocation
    Randomized
    Enrollment
    30 (Anticipated)

    8. Arms, Groups, and Interventions

    Arm Title
    Lean adolescents
    Arm Type
    Experimental
    Arm Description
    15 lean adolescents (BMI Under the national cut-offs for obesity), 12-15 years old, males, will be recruited
    Arm Title
    Obese adolescents
    Arm Type
    Experimental
    Arm Description
    15 obese adolescents (BMI above the national cut-offs for obesity), 12-15 years old, males, will be recruited
    Intervention Type
    Behavioral
    Intervention Name(s)
    acute exercise
    Primary Outcome Measure Information:
    Title
    energy intake in kcal
    Description
    buffet meal
    Time Frame
    up to 2 months

    10. Eligibility

    Sex
    Male
    Minimum Age & Unit of Time
    12 Years
    Maximum Age & Unit of Time
    15 Years
    Accepts Healthy Volunteers
    Accepts Healthy Volunteers
    Eligibility Criteria
    Inclusion Criteria: 12 to 15 years old adolescents Obese according to international values for BMI Being registered to the national social security insurance no eating disorders no medications metabolic disorders Exclusion Criteria: metabolic disorders food disorders physical disability

    12. IPD Sharing Statement

    Learn more about this trial

    Exercise Intensity and Appetite in Adolescents

    We'll reach out to this number within 24 hrs