Back to resultsPALbociclib CoLlaborative Adjuvant Study (PALLAS)
Primary Purpose
Breast Cancer
Status
Active
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Palbociclib
Standard Adjuvant Endocrine Therapy
Sponsored by
About this trial
This is an interventional treatment trial for Breast Cancer focused on measuring HR+/HER2- breast cancer, Palbociclib
Eligibility Criteria
Inclusion Criteria:
- Signed informed consent prior to study specific procedures.
- Age ≥18 years (or per national guidelines).
- Pre- and postmenopausal women or men with Stage II (Stage IIA limited to max. 1000 patients) or Stage III early invasive breast cancer
- Patients with multicentric and/or multifocal and/or bilateral early invasive breast cancer are eligible if all histopathologically examined tumors meet pathologic criteria for ER+ and/or PR+ and HER2-.
- Patients must have histologically confirmed ER+ and/or PR+, HER2-, early invasive breast cancer.
- Patients must have undergone adequate (definitive) breast surgery for the current malignancy.
FFPE tumor tissue block must be confirmed to be received at the central sample repository prior to randomization.
- ECOG performance status 0-1.
- Patients must be able and willing to swallow and retain oral medication.
- Serum or urine pregnancy test must be negative in premenopausal women within 14 days of randomization, or in women with amenorrhea of less than 12 months at time of randomization.
- Patients who received neo/adjuvant therapy must be after last dose of chemotherapy and/or biologic therapy and must have sufficient resolution of side effects.
- Patients who received breast/axilla/post-mastectomy chest wall radiotherapy must be after last dose of radiotherapy and must have sufficient resolution of side effects.
- Patients must have sufficient resolution of any surgical side effects (no active wound healing complications).
-Patients must either be initiating or have already started adjuvant hormonal treatment. -
- Patients who already received neo/adjuvant endocrine therapy are eligible as long as they are enrolled within 12 months of initial histological diagnosis and after completing no more than 6 months of adjuvant endocrine therapy.
- Absolute neutrophil count ≥ 1,500/µL
- Platelets ≥ 100,000/ mm3
- Hemoglobin ≥ 10g/dL
- Total serum bilirubin ≤ ULN; or total bilirubin ≤ 3.0 × ULN with direct bilirubin within normal range in patients with documented Gilbert's Syndrome.
- Aspartate amino transferase (AST or SGOT) and alanine amino transferase (ALT or SGPT) ≤ 1.5 × institutional ULN.
- Serum creatinine below the upper limit of the institutional normal range (ULN) or creatinine clearance ≥ 60 mL/min/1.73 m2 for patients with serum creatinine levels above institutional ULN.
Exclusion Criteria:
- Concurrent therapy with other Investigational Products.
- Prior therapy with any CDK inhibitor.
- Patients with Stage I or IV breast cancer are not eligible.
- History of allergic reactions attributed to compounds of chemical or biologic composition similar to palbociclib.
- Patients receiving any medications or substances that are potent inhibitors or inducers of
- CYP3A isoenzymes within 7 days of randomization.
- Uncontrolled intercurrent illness that would limit compliance with study requirements.
- Pregnant women, or women of childbearing potential without a negative pregnancy test within 14 days prior to randomization.
- Patients with a history of any malignancy are ineligible
- Patients who previously received endocrine therapy within 5 years prior to diagnosis of the current malignancy.
- Patients on antiretroviral therapy.
- Patients with clinically significant history of any chronic liver disease.
- Patients receiving concurrent exogenous hormone therapy (topical vaginal estrogen therapy is allowable).
Sites / Locations
- University of South Alabama Mitchell Cancer Institute
- Southern Cancer Center PC - Providence
- Katmai Oncology Group
- Providence Alaska Cancer Center
- Mayo Clinic in Arizona
- Kaiser Permanente Anaheim Medical Center
- Kaiser Permanente Baldwin Park Medical Center
- Kaiser Permanente Bellflower Medical Center
- Kaiser Permanente Fontana Medical Center
- Marin Cancer Care
- Marin Cancer Center
- Kaiser Permanente Harbor City Medical Center
- Kaiser Permanente Irvine Medical Center
- UCSD Moores Cancer Center
- Long Beach Memorial Medical Center - Todd Cancer Institute
- Kaiser Permanente Sunset Medical Center
- Cedars Sinai Medical Center
- Kaiser Permanente Oakland Medical Center
- Palo Alto Medical Foundation Health Care
- Kaiser Permanente Panorama City Medical Center
- Kaiser Permanente Riverside Medical Center
- Kaiser Permanente Roseville Medical Center
- Kaiser Permanente Sacramento Medical Center
- University of California
- Kaiser Permanente San Diego Medical Center
- Sharp Memorial Hospital
- Kaiser Permanente San Francisco Medical Center
- UCSF Helen Diller Comprehensive Cancer Center
- Kaiser Permanente San Jose Medical Center
- Kaiser Permanente San Leandro Medical Center
- Kaiser Permanente San Marcos Medical Center
- Kaiser Permanente Santa Clara Medical Center
- Kaiser Permanente South San Francisco Medical Center
- Stanford Women's Cancer Center
- Kaiser Permanente Vallejo Medical Center
- Kaiser Permanente Walnut Creek Medical Center
- Kaiser Permanente Cadillac Medical Center
- Kaiser Permanente Woodland Hills Medical Center
- Western States Cancer Research NCORP
- Hartford Hospital
- Memorial Sloan Cancer Center - Hartford Healthcare Center Institute at HOCC
- Christiana Health System - Christiana Hospital
- Georgetown University Medical Center
- George Washington University Medical Faculty Associates
- Morton Plant Hospital
- Mayo Clinic in Florida
- Mount Sinai Comprehensive Cancer Center
- University of Miami Miller School of Medicine Sylvester Cancer Center
- Advent Health Orlando
- Orlando Health Cancer Institute
- Phoebe Putney Memorial Hospital
- Emory University Hospital
- Memorial Health University Medical Center
- Rush University Medical Center
- University of Illinois
- University of Chicago Cancer Center LAPS
- Cancer Care Specialist of Central Illinois
- Decatur Memorial Hospital
- NorthShore University Health System - Evanston Hospital
- Ingalls Memorial Hospital
- Joliet Oncology Hematology Associates Limited
- Advocate Lutheran General Hospital
- Illinois CancerCare-Peoria
- OSF Saint Anthony Medical Center
- Orchard Healthcare Research Inc.
- NorthShore Hematology Oncology-Libertyville
- Carle Cancer Center
- Indiana University - Melvin and Bren Simon Cancer Center LAPS
- IU Health Ball Memorial Hospital
- McFarland Clinic PC-William R Bliss Cancer Center
- McFarland Clinic, P.C.
- Physicians' Clinic of Iowa PC
- Iowa Oncology Research Assoc
- Medical Oncology and Hematology Associates - Des Moines
- Covenant Medical Center
- University of Kentucky-Markey Cancer Center
- Norton Cancer Institute - Brownsboro
- Ochsner Medical Center
- Eastern Maine Medical Center d/b/a Northern Light Cancer Institute
- New England Cancer Specialists - Scarborough
- Anne Arundel Medical Center
- Mercy Medical Center
- Greater Baltimore Medical Center
- MedStar Good Samaritan Hospital
- MedStar Franklin Square Medical Center Winberg Cancer Institute
- Medstar Union Memorial Hospital
- JHU Sidney Kimmel Comprehensive Cancer Center LAPS
- Frederick Regional Health System James M Stockman Cancer Institute
- Maryland Oncology Hematology PA
- Tidal Health Peninsula Regional
- Holy Cross Hospital
- Tufts Medical Center
- Massachusetts General Hospital
- Dana Farber Cancer Institute
- Beth Israel Deaconess Medical Center
- Lowell General Hospital
- Beth Israel Deaconess Hospital - Plymouth Jordan Club Cancer Center
- Saint Joseph Mercy Hospital
- Cancer Research Consortium of West Michigan NCORP
- Spectrum Health Butterworth Research Pharmacy
- Trinity Health Michigan
- Essentia Health NCORP
- Mayo Clinic-Rochester
- Mayo Clinic
- Coborn Cancer Center at Saint Cloud Hospital
- Metro Minnesota Community Oncology Research Consortium
- Metro Minnesota Oncology Research Consortium
- St. Luke's Hospital
- Phelps Country Regional Medical Center
- Washington University School of Medicine
- Missouri Baptist Medical Center
- Mercy Hospital Saint Louis
- Cancer Research for the Ozarks NCORP
- Nebraska Hematology and Oncology
- Southeast Nebraska Cancer Center
- Cancer Alliance of Nebraska
- Missouri Valley Cancer Consortium
- New Hampshire Oncology-Hematology PA, Concord
- New Hampshire Oncology-Hematology PA
- Solinsky Center for Cancer Care
- Dartmouth Hitchcock Medical Center
- Norris Cotton Cancer Center - Nashua
- Englewood Hospital and Medical Center
- Hackensack University Medical Center
- Rutgers Cancer Center Institute of New Jersey
- Robert Wood Johnson University Hospital Somerset
- University of New Mexico Comprehensive Cancer Center
- Montefiore Medical Center - Einstein Campus
- Roswell Park Cancer Institute
- Mary Imogene Bassett Hospital
- Hematology Oncology Associates of Central New York - East Syracuse
- Queens Hospital Center
- Northwell Health NCORP
- Beth Israel Medical Center - New York
- Laura and Isaac Perlmutter Cancer Center at NYU Langone
- Memorial Sloan Kettering Cancer Center - LAPS
- Oneonta FoxCare Center
- SUNY Upstate Medical University
- Carolinas Medical Center/Levine Cancer Institute
- The Charlotte-Mecklenburg Hospital Authority
- Duke University Medical Center
- Cone Health Cancer Center
- Kinston Medical Specialists, PA
- First Health of the Carolinas - Moore Regional Hospital
- Cleveland Clinic Cancer Center/Fairview Hospital
- Cleveland Clinic
- Ohio State University Comprehensive Cancer Center
- Cleveland Clinic Cancer Center/Hillcrest Hospital
- Cancer Centers of Southwest Oklahoma Research
- Stephenson Cancer Center
- University of Oklahoma Health Sciences Center
- Providence Portland Medical Center
- Hematology & Oncology Associates of Northeastern PA
- Penn State Milton S Hershey Medical Center
- Lancaster General Hospital
- Hospital of the University of Pennsylvania Perelman Center for Advanced Medicine
- University of Pennsylvania/Abramson Cancer Center
- Pennsylvania Hospital
- Thomas Jefferson University
- Fox Chase Cancer Center
- Allegheny General Hospital
- UPMC MaGee Women's Hospital
- University of Pittsburgh Cancer Institute- Hillman Cancer Center
- Reading Hospital/McGlinn Cancer Institute
- WellSpan Health York Cancer Center
- Rhode Island Hospital
- Women & Infants Hospital of Rhode Island
- Lexington Medical Center/Lexington Oncology Associates
- Avera Cancer Institute-Aberdeen
- Monument Health Rapid City Hospital
- Rapid City Regional Hospital/Regional Cancer Care Institute
- Avera Cancer Institute
- Vanderbilt University/Ingram Cancer Center
- Nashville General Hospital at Meharry
- Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
- Houston Methodist Hospital Cancer Center
- MD Anderson Cancer Center
- Doctors Hospital of Laredo
- Huntsman Cancer Institute - University of Utah
- Inova Schar Cancer Institute
- VCU Massey Cancer Center
- CAMC Cancer Center
- ThedaCare Regional Cancer Center
- HSHS Saint Vincent Hospital
- Gunderson Lutheran Medical Center
- University of Wisconsin Hospital and Clinics
- Wheaton Franciscan Healthcare - St. Joseph
- Columbia St. Mary's Water Tower Medical Commons
- Wheaton Franciscan Healthcare-All Saints
- Orchard Healthcare Research Inc.
- UW Cancer Center at ProHealth Care
- Wheaton Franciscan Healthcare - Wauwatosa
- Southern Highlands Cancer Centre
- Coffs Harbour Health Campus - MNCCI
- The Breast & Endocrine Centre
- Gosford Hospital
- Macquarie University Hospital
- Orange Health Service
- Wollongong Hospital
- Royal Brisbane & Women's Hospital
- Flinders Drive
- Royal Hobart Hospital
- The Northern Hospital
- St Vincent's Hospital
- Peninsula Health - Frankston Hospital
- University Hospital, Geelong
- Peter MacCallum Cancer Centre
- Peninsula Health - Frankston Hospital
- Western Health, Sunshine Hospital
- South West Healthcare, Warrnambool
- St John of God Bunbury Hospital
- Fiona Stanley Hospital
- Breast Cancer Research Centre - WA
- LKH Feldkirch, Department of Internal Medicine
- LKH Univ Klinikum Graz, Dept of Internal Med. and Oncology
- Medical University of Graz, Gyn. Dept.
- University Hospital Innsbruck, Department of Obstetrics and Gynaecology
- BKH Kufstein, Innere Medizin
- LKH Hochsteiermark Leoben
- Hospital of the Sisters of Charity Linz, Surg. Dept., Breast Health Center
- Kepler Universitätsklinikum Med. Campus III
- Weinviertelklinikum Mistelbach, Department of Surgery
- BHS Ried, Abt. f. Gynäkologie
- LKH Salzburg, Univ. Klinik f. Innere Med. III
- Universitätsklinikum St. Pölten, Innere Medizin
- Breast Centre Dr. Wette Viktor
- Phyrn-Eisenwurzen Klinikum Steyr
- Medical University of Vienna Department of Obstetrics and Gynaecology
- Medical University Vienna - Coop Group Surgery/Oncology
- Hospital Hietzing, Gynecology
- St. Josef Krankenhaus, Department of Internal I
- Klinik Ottakring
- Salzkammergut-Klinikum Vöcklabruck
- Brustordination Dr. Thiel
- Klinikum Wels - Grieskirchen GmbH, Department of Internal Medicine IV
- LKH Wolfsberg, Department of Surgery
- Landesklinikum Wr. Neustadt, Department of Surgery
- OLV ziekenhuis Aalst/Radiotherapy-Oncology
- CHU Saint Pierre/Medical Oncology
- Institut Jules Bordet/Medical Oncology Department
- Cliniques Universitaires Saint-Luc, Oncologisch centrum
- Grand Hopital de Charleroi - Oncologie-hématologie
- University Hospital Antwerp (UZA)
- UZ Leuven/ Gynaecologie-Oncologie
- CHC - Saint-Joseph/Oncology-Hematology
- CHU Sart Tilman Liège (Medical Oncology)
- Clinique et Maternite Sainte-Elisabeth - Oncology Department
- CHR - Centre Hospitalier Peltzer La Tourelle/ Oncology Department
- GZA Ziekenhuizen (Campus Sint-Augustinus) / Oncologische Centrum
- Tom Baker Cancer Centre - Dept. of Oncology
- BC Cancer Agency- Abbotsford Centre
- BC Cancer Agency - Sindi Ahluwalia Hawkins Centre for the Southern Interior
- BC Cancer Agency - Vancouver Cancer Centre
- CancerCare Manitoba - St. Boniface Hospital
- The Vitalite Health Network - Dr. Leon Richard
- Horizon Health Network - Saint John Regional Hospital
- Queen Elizabeth II Health Sciences Centre
- Juravinski Cancer Centre
- Kingston General Hospital, Cancer Centre of Southeastern Ontario/Oncology
- Grand River Regional Cancer Center
- Niagara Health System
- Sunnybrook
- University Health Network Princess Margaret Cancer Centre
- The Jewish General Hospital
- CHUM Hôtel Dieu
- CHU de Québec - Hôpital du St Sacrement
- Allan Blair Cancer Centre
- Saskatoon Cancer Center, University of Saskatchewan
- University Hospital Aachen
- Praxisklinik Krebsheilkunde für Frauen
- Helios Klinikum Berlin-Buch
- Studienzentrum City
- Marienhospital Bottrop, Klinik für Gynäkologie und Geburtshilfe
- Studien GbR Braunschweig, Lorenz&HeckerWesche
- Praxis und Tagesklinik für gynäkologische Onkologie,
- MVZ Eggenfelden
- Frauenklinik/University Hospital Erlangen
- Centrum für Hämatologie und Onkologie Bethanien
- Agaplesion Markus Krankenhaus
- Klinikum Frankfurt Höchst
- Onkol. GP Dres. med. Wilke/Wagner/Petzoldt
- Universitätsfrauenklinik Halle (Saale)
- University Medical Center Hamburg-Eppendorf, Department of Gynecology
- Albertinen Krankenhaus
- Städtisches Klinikum Karlsruhe
- Elisabeth Krankenhaus Kassel Brustzentrum
- St. Elisabeth Krankenhaus Leipzig
- St. Vincenz KH Limburg Frauenklinik
- UKSH Campus Lübeck, Klinik für Frauenheilkunde und Geburtshilfe
- Universitätsmedizin Mainz
- Praxis Gynäkologie Arabella
- University Clinic Oldenburg
- Oncologianova GmbH
- HELIOS Klinik Rottweil - Gynäkologie
- St. Josefs-Hospital
- Országos Onkológiai Intézet - "B" Belgyógyászati Onkológiai és Klinikai Farmakológiai Osztály
- Uzsoki Utcai Kórház - Onkoradiológia, Sugárterápia, Fővárosi Onkoradiológiai Központ
- University of Debrecen Medical Center, Clinic of Oncology
- Petz Aladár Megyei Oktatókórház - Onkoradiológiai Osztály
- Szegedi Tudomanyegyetem Általános Orvostudományi Kar Szent-Györgyi Albert Klinikai Központ, Onkoterápiás Klinika
- Bon Secours Hospital, Cork
- Cork University Hospital, Oncology Clinical Trials Unit
- Beaumont Hospital - Cancer Clinical Trials Unit
- Mater Misericordiae University Hospital
- St James's Hospital, Cancer Clinical Trials Office, Old Admin Building,
- St Vincent Hospital - Medical Oncology Research Department
- University Hospital Limerick, Midwestern Cancer Centre
- Sligo University Hospital
- University Hospital Waterford, Cancer Research Department
- Rabin Medical Center (RMC)
- Sheba Medical Center Tel Hashomer
- Sourasky Medical Center
- Azienda Ospedaliero-Universitaria di Ferrara
- Azienda Ospedaliero-Universitaria Careggi/Florence University/Radiation Oncology Unit
- Department of Internal Medicine (DIMI) - IRCCS San Martino University Hospital
- P.O. Misericordia AUSL Toscana Sud Est
- Ospedale "Mater Salutis" di Legnago, Dept. of Medical Oncology
- Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.) IRCCS
- Ospedale San Raffaele
- Istituto Europeo di Oncologia
- Policlinico di Monza - Istituto di Oncologia del Policlinico di Monza
- Medical Oncology Unit; University Hospital of Parma (Azienda Ospedaliero-Universitaria di Parma)
- Nuovo Ospedale di Prato (NOP) - Azienda USL4 Prato
- ASST Bergamo Ovest
- S. Anna Hospital (Ospedale Sant'Anna)- Turin
- Nagoya City University Hospital/Dept. of Breast & Endocrine Surgery
- Department of Breast Surgery National Hospital Organization Hokkaido Cancer Center
- Chiba Cancer Center
- Kyoto University Hospital/Breast Surgery
- National Hospital Organization Osaka National Hospital
- Osaka International Cancer Institute
- Seoul National University Hospital, Hematology-Medical Oncology
- Severance Hospital Medical Doctor at Department of Medical Oncology
- Samsung Medical Centre, Breast Cancer Center, Department of Medicine, Division of Hematology/Oncology
- Centro Médico Zambrano Hellion
- Centro Oncológico Estatal ISSEMYM
- National Cancer Institute Mexico, Breast Cancer Department
- Hagaziekenhuis
- Máxima Medisch Centrum
- Zuyderland Ziekenhuis, Oncology
- St Antonius Hospital
- Zaans Medical Center
- Isala, Dept of Medical Oncology
- Uniwersyteckie Centrum Kliniczne (UCK), Klinika Onkologii I Radioterapii
- Opolskie Centrum Onkologii, Oddzial Onkologii Klinicznej
- Klinika Nowotworów Piersi i Chirurgii Rekonstrukcyjnej, Centrum Onkologii-Instytut im. Marii Skłodowskiej-Curie
- Instytut MSF Spółka z ograniczoną odpowiedzialnością
- Instituto Português de Oncologia (IPO) de Lisboa Francisco Gentil
- Hospital da Luz
- CUF Descobertas Hospital, Hemato-Oncologia
- Centro Clinico Champalimaud
- Instituto Português de Oncologia (IPO) Francisco Gentil do Porto
- Complejo Hospitalario Universitario A Coruña (CHUAC)
- Centro Oncologico de Galicia
- Hospital General Universitario Alicante
- ICO Badalona
- Hospital del Mar
- Hospital Universitari Quirón Dexeus
- Hospital Clinic Barcelona
- Hospital General de Granollers
- Instituto Catalán de Oncología (ICO) de L'Hospitalet de Llobregat
- Hospital Vall d´Hebron
- Hospital Universitario de Burgos
- Consorcio Hospitalario Provincial de Castellon
- San Pedro de Alcántara
- Hospital Reina Sofía
- Hospital General Universitario de Elche
- ICO/ H. Josep Trueta
- Complejo asistencial universitario de Leon
- Hospital Universitario Gregorio Marañón
- MD Anderson Cancer Center
- Hospital Universitario Ramon y Cajal
- Fundación Jiménez Díaz
- Hospital Universitario 12 de Octubre
- Hospital La Paz, Servicio de Oncologia Médica
- CIOCC - Centro Integral Oncológico Clara Campal / Hospital HM Universitario Sanchinarro
- Hospital Puerta de Hierro Majadahonda, Oncologia Médica
- Hospital Universitario Fundacion Alcorcón
- Hospital General Universitario José Mª Morales Meseguer
- Hospital Clínico Universitario Virgen de la Arrixaca
- Hospital Clínico Universitario Virgen de la Victoria
- Hospital Universitario Central de Asturias
- Hospitali Universitari son Espases
- Hospital Son Llatzer
- Complejo Hospitalario de Navarra
- Hospital Universitari Sant Joan de Reus
- Hospital Universitario Donostia
- Hospital de Sant Juan Despi Moisés Broggi
- Hospital Clinico Universitario de Santiago
- Hospital Unversitario Virgen Macarena
- Hospital Quirón Sagrado Corazón
- Hospital Universitario Virgen del Rocio
- Consorci Sanitari de Terrassa
- Hospital Virgen de la Salud
- Hospital Clínico Universitario de Valencia
- Hosital Arnau de Vilanova Valencia
- Hospital Clinico Universitario Lozano Blesa
- Hospital Universitario Miguel Servet
- Gävle Hospital, Dept. of Oncology
- Sahlgrenska University Hospital, Dept. Oncology
- Karolinska Universitetssjukhuset, Bröstcentrum A2:00
- Akademiska Sjukhuset Uppsala (University Hospital), Onkologkliniken
- Universitetssjukhuset Örebro (University Hospital) Örebro, Onkologkliniken
- Kantonspital Baden
- Spital STS AG, Onkologiezentrum Thun-Berner Oberland
- Hôpitaux Universitaires de Genève
- Kantonsspital Graubünden
- IOSI-Breast Cancer Unit-Ospedale San Giovanni-Bellinzona
- Fondazione Oncologia Lago Maggiore, Locarno
- Dep. Oncology, University Hospital
- HFR Fribourg, Oncology Department
- Luzerner Kantonsspital, Dept. of Medical Oncology
- Onkologisches Forschungszentrum Klinik St. Anna, Hirslanden
- Kantonsspital St.Gallen, Onkologie/Hämatologie
- Brust-Zentrum Zürich
- Universitätsspital Zürich, Klinik für Onkologie
- Changhua Christian Hospital/General Surgery
- Kaohsiung Medical University Hospital
- National Cheng Kung University Hospital, Division of Hemato-Oncology, Dept. Internal Medicine
- National Taiwan University Hospital/Department of Surgery
- Taipei Veterans General Hospital/General Surgery
- City Hospital Birmingham
- University Hospitals Bristol NHS Foundation Trust
- Velindre Cancer Centre
- Royal Marsden Hospital Chelsea
- The Beatson West of Scotland Cancer Centre
- University Hospitals of Leicester
- Royal Liverpool University Hospital
- Guy's and St Thomas' NHS Foundation Trust
- The Royal Marsden Sutton
- Charing Cross Hospital
- Maidstone Hospital, Kent Oncology Centre
- The Christie NHS Foundation Trust
- Northern Centre for Cancer Care
- Nottingham University Hospitals NHS TRUST UK
- Weston Park Hospital, Sheffield Teaching Hospitals
- Royal Cornwall Hospitals NHS Trust, Oncology Trials, Sunrise Centre
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Other
Arm Label
Arm A
Arm B
Arm Description
Palbociclib at a dose of 125 mg orally once daily, Day 1 to Day 21 followed by 7 days off treatment in a 28-day cycle for a total duration of 2 years, in addition to standard adjuvant endocrine therapy for a duration of at least 5 years.
Standard adjuvant endocrine therapy for a duration of at least 5 years.
Outcomes
Primary Outcome Measures
Invasive Disease Free Survival (iDFS)
Invasive disease-free survival (iDFS) for the combination of at least 5 years endocrine therapy and 2-year palbociclib treatment versus at least 5 years endocrine therapy alone in patients with histologically confirmed HR+/HER2- invasive early breast cancer (EBC) at 4 years. iDFS is defined as the time from randomization to the date of the first event: local/regional invasive ipsilateral recurrence, contralateral invasive breast cancer, distant recurrence, second primary invasive cancer of non-breast origin or death from any cause. Direct comparison between arms used time to iDFS events and Kaplan-Meier Log-rank analysis. Due to the medians not yet achieved, the percentage of patients considered iDFS at 4 years is reported.
Secondary Outcome Measures
Invasive Disease Free Survival (iDFS) Excluding Second Primary Invasive Cancers of Non-breast Origin.
Invasive disease-free survival (iDFS, excluding second primary invasive cancers of non-breast origin) for the combination of at least 5 years endocrine therapy and 2-year palbociclib treatment versus at least 5 years endocrine therapy alone in patients with histologically confirmed HR+/HER2- invasive early breast cancer (EBC) at 4 years. iDFS excluding second primary invasive cancers of non-breast origin is defined as the time from randomization to the date of the first event: local/regional invasive ipsilateral recurrence, contralateral invasive breast cancer, distant recurrence, or death from any cause. Second primary invasive cancers of non-breast origin will not be considered as events for this endpoint. Direct comparison between arms used time to iDFS events and Kaplan-Meier Log-rank analysis. Due to the medians not yet achieved, the percentage of patients considered iDFS at 4 years is reported.
Distant Recurrence-free Survival (DRFS)
Compare time to distant recurrence-free survival (DRFS). Distant recurrence is defined according to STEEP criteria as the time from randomization to the date of the first event: distant recurrence or death from any cause. Patients with a locoregional recurrence will continue to be followed for DRFS. Surviving patients who are event-free will be censored at: the date of last disease assessment, or withdrawal of consent to be followed, or death whichever came first. Direct comparison between arms used time to DRFS events and Kaplan-Meier Log-rank analysis. Due to the medians not yet achieved, the percentage of patients considered DRFS at 4 years is reported.
Overall Survival (OS)
Compare overall survival (OS). Overall survival is defined as the time period between randomization and death. Surviving patients classified as lost-to-follow up or having withdrawn consent to be followed will be censored at their date of last contact or withdrawal of consent to be followed, whichever occurs first.
Locoregional Recurrences-free Survival (LRRFS)
Compare locoregional recurrence-free survival (LRRFS). LRRFS is defined as the time from randomization to the date of the first event: local/regional invasive ipsilateral recurrence, contralateral invasive breast cancer, or death from any cause. Patients with second primary invasive cancers of non-breast origin or distant recurrence will be censored at the date of diagnosis. Surviving patients who are event-free will be censored at: the date of last disease assessment, or withdrawal of consent to be followed, whichever occurs first.
Full Information
NCT ID
NCT02513394
First Posted
July 29, 2015
Last Updated
June 13, 2023
Sponsor
Alliance Foundation Trials, LLC.
Collaborators
Austrian Breast & Colorectal Cancer Study Group, NSABP Foundation Inc, PrECOG, LLC., Breast International Group, Pfizer
1. Study Identification
Unique Protocol Identification Number
NCT02513394
Brief Title
PALbociclib CoLlaborative Adjuvant Study
Acronym
PALLAS
Official Title
PALbociclib CoLlaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR+) / Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Early Breast Cancer
Study Type
Interventional
2. Study Status
Record Verification Date
April 2023
Overall Recruitment Status
Active, not recruiting
Study Start Date
August 2015 (undefined)
Primary Completion Date
November 2020 (Actual)
Study Completion Date
September 2025 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Alliance Foundation Trials, LLC.
Collaborators
Austrian Breast & Colorectal Cancer Study Group, NSABP Foundation Inc, PrECOG, LLC., Breast International Group, Pfizer
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
This is a prospective, two arm, international, multicenter, randomized, open-label Phase III study evaluating the addition of 2 years of palbociclib to standard adjuvant endocrine therapy for patients with HR+ / HER2- early breast cancer (EBC).
The purpose of the PALLAS study is to determine whether the addition of palbociclib to adjuvant endocrine therapy will improve outcomes over endocrine therapy alone for HR+/HER2- early breast cancer. Assessment of a variety of correlative analysis, including evaluation of the effect of palbociclib in genomically defined tumor subgroups, is planned.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Breast Cancer
Keywords
HR+/HER2- breast cancer, Palbociclib
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
5796 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Arm A
Arm Type
Experimental
Arm Description
Palbociclib at a dose of 125 mg orally once daily, Day 1 to Day 21 followed by 7 days off treatment in a 28-day cycle for a total duration of 2 years, in addition to standard adjuvant endocrine therapy for a duration of at least 5 years.
Arm Title
Arm B
Arm Type
Other
Arm Description
Standard adjuvant endocrine therapy for a duration of at least 5 years.
Intervention Type
Drug
Intervention Name(s)
Palbociclib
Intervention Type
Drug
Intervention Name(s)
Standard Adjuvant Endocrine Therapy
Primary Outcome Measure Information:
Title
Invasive Disease Free Survival (iDFS)
Description
Invasive disease-free survival (iDFS) for the combination of at least 5 years endocrine therapy and 2-year palbociclib treatment versus at least 5 years endocrine therapy alone in patients with histologically confirmed HR+/HER2- invasive early breast cancer (EBC) at 4 years. iDFS is defined as the time from randomization to the date of the first event: local/regional invasive ipsilateral recurrence, contralateral invasive breast cancer, distant recurrence, second primary invasive cancer of non-breast origin or death from any cause. Direct comparison between arms used time to iDFS events and Kaplan-Meier Log-rank analysis. Due to the medians not yet achieved, the percentage of patients considered iDFS at 4 years is reported.
Time Frame
4 years
Secondary Outcome Measure Information:
Title
Invasive Disease Free Survival (iDFS) Excluding Second Primary Invasive Cancers of Non-breast Origin.
Description
Invasive disease-free survival (iDFS, excluding second primary invasive cancers of non-breast origin) for the combination of at least 5 years endocrine therapy and 2-year palbociclib treatment versus at least 5 years endocrine therapy alone in patients with histologically confirmed HR+/HER2- invasive early breast cancer (EBC) at 4 years. iDFS excluding second primary invasive cancers of non-breast origin is defined as the time from randomization to the date of the first event: local/regional invasive ipsilateral recurrence, contralateral invasive breast cancer, distant recurrence, or death from any cause. Second primary invasive cancers of non-breast origin will not be considered as events for this endpoint. Direct comparison between arms used time to iDFS events and Kaplan-Meier Log-rank analysis. Due to the medians not yet achieved, the percentage of patients considered iDFS at 4 years is reported.
Time Frame
4 years
Title
Distant Recurrence-free Survival (DRFS)
Description
Compare time to distant recurrence-free survival (DRFS). Distant recurrence is defined according to STEEP criteria as the time from randomization to the date of the first event: distant recurrence or death from any cause. Patients with a locoregional recurrence will continue to be followed for DRFS. Surviving patients who are event-free will be censored at: the date of last disease assessment, or withdrawal of consent to be followed, or death whichever came first. Direct comparison between arms used time to DRFS events and Kaplan-Meier Log-rank analysis. Due to the medians not yet achieved, the percentage of patients considered DRFS at 4 years is reported.
Time Frame
4 years
Title
Overall Survival (OS)
Description
Compare overall survival (OS). Overall survival is defined as the time period between randomization and death. Surviving patients classified as lost-to-follow up or having withdrawn consent to be followed will be censored at their date of last contact or withdrawal of consent to be followed, whichever occurs first.
Time Frame
4 years
Title
Locoregional Recurrences-free Survival (LRRFS)
Description
Compare locoregional recurrence-free survival (LRRFS). LRRFS is defined as the time from randomization to the date of the first event: local/regional invasive ipsilateral recurrence, contralateral invasive breast cancer, or death from any cause. Patients with second primary invasive cancers of non-breast origin or distant recurrence will be censored at the date of diagnosis. Surviving patients who are event-free will be censored at: the date of last disease assessment, or withdrawal of consent to be followed, whichever occurs first.
Time Frame
4 years
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Signed informed consent prior to study specific procedures.
Age ≥18 years (or per national guidelines).
Pre- and postmenopausal women or men with Stage II (Stage IIA limited to max. 1000 patients) or Stage III early invasive breast cancer
Patients with multicentric and/or multifocal and/or bilateral early invasive breast cancer are eligible if all histopathologically examined tumors meet pathologic criteria for ER+ and/or PR+ and HER2-.
Patients must have histologically confirmed ER+ and/or PR+, HER2-, early invasive breast cancer.
Patients must have undergone adequate (definitive) breast surgery for the current malignancy.
FFPE tumor tissue block must be confirmed to be received at the central sample repository prior to randomization.
ECOG performance status 0-1.
Patients must be able and willing to swallow and retain oral medication.
Serum or urine pregnancy test must be negative in premenopausal women within 14 days of randomization, or in women with amenorrhea of less than 12 months at time of randomization.
Patients who received neo/adjuvant therapy must be after last dose of chemotherapy and/or biologic therapy and must have sufficient resolution of side effects.
Patients who received breast/axilla/post-mastectomy chest wall radiotherapy must be after last dose of radiotherapy and must have sufficient resolution of side effects.
Patients must have sufficient resolution of any surgical side effects (no active wound healing complications).
-Patients must either be initiating or have already started adjuvant hormonal treatment. -
Patients who already received neo/adjuvant endocrine therapy are eligible as long as they are enrolled within 12 months of initial histological diagnosis and after completing no more than 6 months of adjuvant endocrine therapy.
Absolute neutrophil count ≥ 1,500/µL
Platelets ≥ 100,000/ mm3
Hemoglobin ≥ 10g/dL
Total serum bilirubin ≤ ULN; or total bilirubin ≤ 3.0 × ULN with direct bilirubin within normal range in patients with documented Gilbert's Syndrome.
Aspartate amino transferase (AST or SGOT) and alanine amino transferase (ALT or SGPT) ≤ 1.5 × institutional ULN.
Serum creatinine below the upper limit of the institutional normal range (ULN) or creatinine clearance ≥ 60 mL/min/1.73 m2 for patients with serum creatinine levels above institutional ULN.
Exclusion Criteria:
Concurrent therapy with other Investigational Products.
Prior therapy with any CDK inhibitor.
Patients with Stage I or IV breast cancer are not eligible.
History of allergic reactions attributed to compounds of chemical or biologic composition similar to palbociclib.
Patients receiving any medications or substances that are potent inhibitors or inducers of
CYP3A isoenzymes within 7 days of randomization.
Uncontrolled intercurrent illness that would limit compliance with study requirements.
Pregnant women, or women of childbearing potential without a negative pregnancy test within 14 days prior to randomization.
Patients with a history of any malignancy are ineligible
Patients who previously received endocrine therapy within 5 years prior to diagnosis of the current malignancy.
Patients on antiretroviral therapy.
Patients with clinically significant history of any chronic liver disease.
Patients receiving concurrent exogenous hormone therapy (topical vaginal estrogen therapy is allowable).
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Suzanne George, MD
Organizational Affiliation
Alliance Foundation Trials, LLC.
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
Erica Mayer, MD
Organizational Affiliation
Dana-Farber Cancer Institute
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
Angela DeMichele, MD
Organizational Affiliation
University of Pennsylvania
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
Michael Gnant, MD
Organizational Affiliation
ABCSG, Medical University Vienna
Official's Role
Principal Investigator
Facility Information:
Facility Name
University of South Alabama Mitchell Cancer Institute
City
Mobile
State/Province
Alabama
ZIP/Postal Code
36604
Country
United States
Facility Name
Southern Cancer Center PC - Providence
City
Mobile
State/Province
Alabama
ZIP/Postal Code
36608
Country
United States
Facility Name
Katmai Oncology Group
City
Anchorage
State/Province
Alaska
ZIP/Postal Code
99508
Country
United States
Facility Name
Providence Alaska Cancer Center
City
Anchorage
State/Province
Alaska
ZIP/Postal Code
99508
Country
United States
Facility Name
Mayo Clinic in Arizona
City
Phoenix
State/Province
Arizona
ZIP/Postal Code
85054
Country
United States
Facility Name
Kaiser Permanente Anaheim Medical Center
City
Anaheim
State/Province
California
ZIP/Postal Code
92806
Country
United States
Facility Name
Kaiser Permanente Baldwin Park Medical Center
City
Baldwin Park
State/Province
California
ZIP/Postal Code
91706
Country
United States
Facility Name
Kaiser Permanente Bellflower Medical Center
City
Bellflower
State/Province
California
ZIP/Postal Code
90706
Country
United States
Facility Name
Kaiser Permanente Fontana Medical Center
City
Fontana
State/Province
California
ZIP/Postal Code
92335
Country
United States
Facility Name
Marin Cancer Care
City
Greenbrae
State/Province
California
ZIP/Postal Code
94904
Country
United States
Facility Name
Marin Cancer Center
City
Greenbrae
State/Province
California
ZIP/Postal Code
94904
Country
United States
Facility Name
Kaiser Permanente Harbor City Medical Center
City
Harbor City
State/Province
California
ZIP/Postal Code
90710
Country
United States
Facility Name
Kaiser Permanente Irvine Medical Center
City
Irvine
State/Province
California
ZIP/Postal Code
92618
Country
United States
Facility Name
UCSD Moores Cancer Center
City
La Jolla
State/Province
California
ZIP/Postal Code
92093
Country
United States
Facility Name
Long Beach Memorial Medical Center - Todd Cancer Institute
City
Long Beach
State/Province
California
ZIP/Postal Code
90806
Country
United States
Facility Name
Kaiser Permanente Sunset Medical Center
City
Los Angeles
State/Province
California
ZIP/Postal Code
90027
Country
United States
Facility Name
Cedars Sinai Medical Center
City
Los Angeles
State/Province
California
ZIP/Postal Code
90048
Country
United States
Facility Name
Kaiser Permanente Oakland Medical Center
City
Oakland
State/Province
California
ZIP/Postal Code
94611
Country
United States
Facility Name
Palo Alto Medical Foundation Health Care
City
Palo Alto
State/Province
California
ZIP/Postal Code
94301
Country
United States
Facility Name
Kaiser Permanente Panorama City Medical Center
City
Panorama City
State/Province
California
ZIP/Postal Code
91402
Country
United States
Facility Name
Kaiser Permanente Riverside Medical Center
City
Riverside
State/Province
California
ZIP/Postal Code
92505
Country
United States
Facility Name
Kaiser Permanente Roseville Medical Center
City
Roseville
State/Province
California
ZIP/Postal Code
95661
Country
United States
Facility Name
Kaiser Permanente Sacramento Medical Center
City
Sacramento
State/Province
California
ZIP/Postal Code
95825
Country
United States
Facility Name
University of California
City
San Diego
State/Province
California
ZIP/Postal Code
92093
Country
United States
Facility Name
Kaiser Permanente San Diego Medical Center
City
San Diego
State/Province
California
ZIP/Postal Code
92120
Country
United States
Facility Name
Sharp Memorial Hospital
City
San Diego
State/Province
California
ZIP/Postal Code
92123
Country
United States
Facility Name
Kaiser Permanente San Francisco Medical Center
City
San Francisco
State/Province
California
ZIP/Postal Code
94115
Country
United States
Facility Name
UCSF Helen Diller Comprehensive Cancer Center
City
San Francisco
State/Province
California
ZIP/Postal Code
94115
Country
United States
Facility Name
Kaiser Permanente San Jose Medical Center
City
San Jose
State/Province
California
ZIP/Postal Code
95119
Country
United States
Facility Name
Kaiser Permanente San Leandro Medical Center
City
San Leandro
State/Province
California
ZIP/Postal Code
94577
Country
United States
Facility Name
Kaiser Permanente San Marcos Medical Center
City
San Marcos
State/Province
California
ZIP/Postal Code
92078
Country
United States
Facility Name
Kaiser Permanente Santa Clara Medical Center
City
Santa Clara
State/Province
California
ZIP/Postal Code
95051
Country
United States
Facility Name
Kaiser Permanente South San Francisco Medical Center
City
South San Francisco
State/Province
California
ZIP/Postal Code
94080
Country
United States
Facility Name
Stanford Women's Cancer Center
City
Stanford
State/Province
California
ZIP/Postal Code
94305
Country
United States
Facility Name
Kaiser Permanente Vallejo Medical Center
City
Vallejo
State/Province
California
ZIP/Postal Code
94589
Country
United States
Facility Name
Kaiser Permanente Walnut Creek Medical Center
City
Walnut Creek
State/Province
California
ZIP/Postal Code
94596
Country
United States
Facility Name
Kaiser Permanente Cadillac Medical Center
City
West Los Angeles
State/Province
California
ZIP/Postal Code
90034
Country
United States
Facility Name
Kaiser Permanente Woodland Hills Medical Center
City
Woodland Hills
State/Province
California
ZIP/Postal Code
91367
Country
United States
Facility Name
Western States Cancer Research NCORP
City
Denver
State/Province
Colorado
ZIP/Postal Code
80222
Country
United States
Facility Name
Hartford Hospital
City
Hartford
State/Province
Connecticut
ZIP/Postal Code
06102
Country
United States
Facility Name
Memorial Sloan Cancer Center - Hartford Healthcare Center Institute at HOCC
City
New Britain
State/Province
Connecticut
ZIP/Postal Code
06053
Country
United States
Facility Name
Christiana Health System - Christiana Hospital
City
Newark
State/Province
Delaware
ZIP/Postal Code
19718
Country
United States
Facility Name
Georgetown University Medical Center
City
Washington
State/Province
District of Columbia
ZIP/Postal Code
20007
Country
United States
Facility Name
George Washington University Medical Faculty Associates
City
Washington
State/Province
District of Columbia
ZIP/Postal Code
20037
Country
United States
Facility Name
Morton Plant Hospital
City
Clearwater
State/Province
Florida
ZIP/Postal Code
33756
Country
United States
Facility Name
Mayo Clinic in Florida
City
Jacksonville
State/Province
Florida
ZIP/Postal Code
32224
Country
United States
Facility Name
Mount Sinai Comprehensive Cancer Center
City
Miami Beach
State/Province
Florida
ZIP/Postal Code
33140
Country
United States
Facility Name
University of Miami Miller School of Medicine Sylvester Cancer Center
City
Miami
State/Province
Florida
ZIP/Postal Code
33136
Country
United States
Facility Name
Advent Health Orlando
City
Orlando
State/Province
Florida
ZIP/Postal Code
32804
Country
United States
Facility Name
Orlando Health Cancer Institute
City
Orlando
State/Province
Florida
ZIP/Postal Code
32806
Country
United States
Facility Name
Phoebe Putney Memorial Hospital
City
Albany
State/Province
Georgia
ZIP/Postal Code
31701
Country
United States
Facility Name
Emory University Hospital
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30322
Country
United States
Facility Name
Memorial Health University Medical Center
City
Savannah
State/Province
Georgia
ZIP/Postal Code
317404
Country
United States
Facility Name
Rush University Medical Center
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60612
Country
United States
Facility Name
University of Illinois
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60612
Country
United States
Facility Name
University of Chicago Cancer Center LAPS
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60637
Country
United States
Facility Name
Cancer Care Specialist of Central Illinois
City
Decatur
State/Province
Illinois
ZIP/Postal Code
62526
Country
United States
Facility Name
Decatur Memorial Hospital
City
Decatur
State/Province
Illinois
ZIP/Postal Code
62526
Country
United States
Facility Name
NorthShore University Health System - Evanston Hospital
City
Evanston
State/Province
Illinois
ZIP/Postal Code
60201
Country
United States
Facility Name
Ingalls Memorial Hospital
City
Harvey
State/Province
Illinois
ZIP/Postal Code
60426
Country
United States
Facility Name
Joliet Oncology Hematology Associates Limited
City
Joliet
State/Province
Illinois
ZIP/Postal Code
60435
Country
United States
Facility Name
Advocate Lutheran General Hospital
City
Park Ridge
State/Province
Illinois
ZIP/Postal Code
60068
Country
United States
Facility Name
Illinois CancerCare-Peoria
City
Peoria
State/Province
Illinois
ZIP/Postal Code
61615
Country
United States
Facility Name
OSF Saint Anthony Medical Center
City
Rockford
State/Province
Illinois
ZIP/Postal Code
61108
Country
United States
Facility Name
Orchard Healthcare Research Inc.
City
Skokie
State/Province
Illinois
ZIP/Postal Code
60017
Country
United States
Facility Name
NorthShore Hematology Oncology-Libertyville
City
Skokie
State/Province
Illinois
ZIP/Postal Code
60077
Country
United States
Facility Name
Carle Cancer Center
City
Urbana
State/Province
Illinois
ZIP/Postal Code
61801
Country
United States
Facility Name
Indiana University - Melvin and Bren Simon Cancer Center LAPS
City
Indianapolis
State/Province
Indiana
ZIP/Postal Code
46202
Country
United States
Facility Name
IU Health Ball Memorial Hospital
City
Muncie
State/Province
Indiana
ZIP/Postal Code
47303
Country
United States
Facility Name
McFarland Clinic PC-William R Bliss Cancer Center
City
Ames
State/Province
Iowa
ZIP/Postal Code
50010
Country
United States
Facility Name
McFarland Clinic, P.C.
City
Ames
State/Province
Iowa
ZIP/Postal Code
50010
Country
United States
Facility Name
Physicians' Clinic of Iowa PC
City
Cedar Rapids
State/Province
Iowa
ZIP/Postal Code
52403
Country
United States
Facility Name
Iowa Oncology Research Assoc
City
Des Moines
State/Province
Iowa
ZIP/Postal Code
50309
Country
United States
Facility Name
Medical Oncology and Hematology Associates - Des Moines
City
Des Moines
State/Province
Iowa
ZIP/Postal Code
50309
Country
United States
Facility Name
Covenant Medical Center
City
Waterloo
State/Province
Iowa
ZIP/Postal Code
50702
Country
United States
Facility Name
University of Kentucky-Markey Cancer Center
City
Lexington
State/Province
Kentucky
ZIP/Postal Code
40536
Country
United States
Facility Name
Norton Cancer Institute - Brownsboro
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
20202
Country
United States
Facility Name
Ochsner Medical Center
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70121
Country
United States
Facility Name
Eastern Maine Medical Center d/b/a Northern Light Cancer Institute
City
Bangor
State/Province
Maine
ZIP/Postal Code
04401
Country
United States
Facility Name
New England Cancer Specialists - Scarborough
City
Scarborough
State/Province
Maine
ZIP/Postal Code
04074
Country
United States
Facility Name
Anne Arundel Medical Center
City
Annapolis
State/Province
Maryland
ZIP/Postal Code
21401
Country
United States
Facility Name
Mercy Medical Center
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21202
Country
United States
Facility Name
Greater Baltimore Medical Center
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21204
Country
United States
Facility Name
MedStar Good Samaritan Hospital
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21218
Country
United States
Facility Name
MedStar Franklin Square Medical Center Winberg Cancer Institute
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21237
Country
United States
Facility Name
Medstar Union Memorial Hospital
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21237
Country
United States
Facility Name
JHU Sidney Kimmel Comprehensive Cancer Center LAPS
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21287
Country
United States
Facility Name
Frederick Regional Health System James M Stockman Cancer Institute
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21701
Country
United States
Facility Name
Maryland Oncology Hematology PA
City
Bethesda
State/Province
Maryland
ZIP/Postal Code
20817
Country
United States
Facility Name
Tidal Health Peninsula Regional
City
Salisbury
State/Province
Maryland
ZIP/Postal Code
21801
Country
United States
Facility Name
Holy Cross Hospital
City
Silver Spring
State/Province
Maryland
ZIP/Postal Code
20910
Country
United States
Facility Name
Tufts Medical Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02111
Country
United States
Facility Name
Massachusetts General Hospital
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02114
Country
United States
Facility Name
Dana Farber Cancer Institute
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02115
Country
United States
Facility Name
Beth Israel Deaconess Medical Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02215
Country
United States
Facility Name
Lowell General Hospital
City
Lowell
State/Province
Massachusetts
ZIP/Postal Code
01852
Country
United States
Facility Name
Beth Israel Deaconess Hospital - Plymouth Jordan Club Cancer Center
City
Plymouth
State/Province
Massachusetts
ZIP/Postal Code
02360
Country
United States
Facility Name
Saint Joseph Mercy Hospital
City
Ann Arbor
State/Province
Michigan
ZIP/Postal Code
48106
Country
United States
Facility Name
Cancer Research Consortium of West Michigan NCORP
City
Grand Rapids
State/Province
Michigan
ZIP/Postal Code
49503
Country
United States
Facility Name
Spectrum Health Butterworth Research Pharmacy
City
Grand Rapids
State/Province
Michigan
ZIP/Postal Code
49503
Country
United States
Facility Name
Trinity Health Michigan
City
Livonia
State/Province
Michigan
ZIP/Postal Code
48152
Country
United States
Facility Name
Essentia Health NCORP
City
Duluth
State/Province
Minnesota
ZIP/Postal Code
55805
Country
United States
Facility Name
Mayo Clinic-Rochester
City
Rochester
State/Province
Minnesota
ZIP/Postal Code
55902
Country
United States
Facility Name
Mayo Clinic
City
Rochester
State/Province
Minnesota
ZIP/Postal Code
55905
Country
United States
Facility Name
Coborn Cancer Center at Saint Cloud Hospital
City
Saint Cloud
State/Province
Minnesota
ZIP/Postal Code
56303
Country
United States
Facility Name
Metro Minnesota Community Oncology Research Consortium
City
Saint Louis Park
State/Province
Minnesota
ZIP/Postal Code
55416
Country
United States
Facility Name
Metro Minnesota Oncology Research Consortium
City
Saint Louis Park
State/Province
Minnesota
ZIP/Postal Code
55416
Country
United States
Facility Name
St. Luke's Hospital
City
Kansas City
State/Province
Missouri
ZIP/Postal Code
64111
Country
United States
Facility Name
Phelps Country Regional Medical Center
City
Rolla
State/Province
Missouri
ZIP/Postal Code
65401
Country
United States
Facility Name
Washington University School of Medicine
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63110
Country
United States
Facility Name
Missouri Baptist Medical Center
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63131
Country
United States
Facility Name
Mercy Hospital Saint Louis
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63141
Country
United States
Facility Name
Cancer Research for the Ozarks NCORP
City
Springfield
State/Province
Missouri
ZIP/Postal Code
65807
Country
United States
Facility Name
Nebraska Hematology and Oncology
City
Lincoln
State/Province
Nebraska
ZIP/Postal Code
68506
Country
United States
Facility Name
Southeast Nebraska Cancer Center
City
Lincoln
State/Province
Nebraska
ZIP/Postal Code
68510
Country
United States
Facility Name
Cancer Alliance of Nebraska
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68106
Country
United States
Facility Name
Missouri Valley Cancer Consortium
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68106
Country
United States
Facility Name
New Hampshire Oncology-Hematology PA, Concord
City
Concord
State/Province
New Hampshire
ZIP/Postal Code
03301
Country
United States
Facility Name
New Hampshire Oncology-Hematology PA
City
Hooksett
State/Province
New Hampshire
ZIP/Postal Code
03106
Country
United States
Facility Name
Solinsky Center for Cancer Care
City
Hooksett
State/Province
New Hampshire
ZIP/Postal Code
03106
Country
United States
Facility Name
Dartmouth Hitchcock Medical Center
City
Lebanon
State/Province
New Hampshire
ZIP/Postal Code
03756
Country
United States
Facility Name
Norris Cotton Cancer Center - Nashua
City
Lebanon
State/Province
New Hampshire
ZIP/Postal Code
03766
Country
United States
Facility Name
Englewood Hospital and Medical Center
City
Englewood
State/Province
New Jersey
ZIP/Postal Code
07631
Country
United States
Facility Name
Hackensack University Medical Center
City
Hackensack
State/Province
New Jersey
ZIP/Postal Code
07601
Country
United States
Facility Name
Rutgers Cancer Center Institute of New Jersey
City
New Brunswick
State/Province
New Jersey
ZIP/Postal Code
08903
Country
United States
Facility Name
Robert Wood Johnson University Hospital Somerset
City
Somerville
State/Province
New Jersey
ZIP/Postal Code
08876
Country
United States
Facility Name
University of New Mexico Comprehensive Cancer Center
City
Albuquerque
State/Province
New Mexico
ZIP/Postal Code
87131
Country
United States
Facility Name
Montefiore Medical Center - Einstein Campus
City
Bronx
State/Province
New York
ZIP/Postal Code
10461
Country
United States
Facility Name
Roswell Park Cancer Institute
City
Buffalo
State/Province
New York
ZIP/Postal Code
14263
Country
United States
Facility Name
Mary Imogene Bassett Hospital
City
Cooperstown
State/Province
New York
ZIP/Postal Code
11326
Country
United States
Facility Name
Hematology Oncology Associates of Central New York - East Syracuse
City
East Syracuse
State/Province
New York
ZIP/Postal Code
13057
Country
United States
Facility Name
Queens Hospital Center
City
Jamaica
State/Province
New York
ZIP/Postal Code
11432
Country
United States
Facility Name
Northwell Health NCORP
City
New Hyde Park
State/Province
New York
ZIP/Postal Code
11042
Country
United States
Facility Name
Beth Israel Medical Center - New York
City
New York
State/Province
New York
ZIP/Postal Code
10011
Country
United States
Facility Name
Laura and Isaac Perlmutter Cancer Center at NYU Langone
City
New York
State/Province
New York
ZIP/Postal Code
10016
Country
United States
Facility Name
Memorial Sloan Kettering Cancer Center - LAPS
City
New York
State/Province
New York
ZIP/Postal Code
10065
Country
United States
Facility Name
Oneonta FoxCare Center
City
Oneonta
State/Province
New York
ZIP/Postal Code
13820
Country
United States
Facility Name
SUNY Upstate Medical University
City
Syracuse
State/Province
New York
ZIP/Postal Code
13210
Country
United States
Facility Name
Carolinas Medical Center/Levine Cancer Institute
City
Charlotte
State/Province
North Carolina
ZIP/Postal Code
28204
Country
United States
Facility Name
The Charlotte-Mecklenburg Hospital Authority
City
Charlotte
State/Province
North Carolina
ZIP/Postal Code
28204
Country
United States
Facility Name
Duke University Medical Center
City
Durham
State/Province
North Carolina
ZIP/Postal Code
27710
Country
United States
Facility Name
Cone Health Cancer Center
City
Greensboro
State/Province
North Carolina
ZIP/Postal Code
27403
Country
United States
Facility Name
Kinston Medical Specialists, PA
City
Kinston
State/Province
North Carolina
ZIP/Postal Code
28504
Country
United States
Facility Name
First Health of the Carolinas - Moore Regional Hospital
City
Pinehurst
State/Province
North Carolina
ZIP/Postal Code
28374
Country
United States
Facility Name
Cleveland Clinic Cancer Center/Fairview Hospital
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44111
Country
United States
Facility Name
Cleveland Clinic
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44195
Country
United States
Facility Name
Ohio State University Comprehensive Cancer Center
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43210
Country
United States
Facility Name
Cleveland Clinic Cancer Center/Hillcrest Hospital
City
Mayfield Heights
State/Province
Ohio
ZIP/Postal Code
44124
Country
United States
Facility Name
Cancer Centers of Southwest Oklahoma Research
City
Lawton
State/Province
Oklahoma
ZIP/Postal Code
73505
Country
United States
Facility Name
Stephenson Cancer Center
City
Oklahoma City
State/Province
Oklahoma
ZIP/Postal Code
73104
Country
United States
Facility Name
University of Oklahoma Health Sciences Center
City
Oklahoma City
State/Province
Oklahoma
ZIP/Postal Code
73104
Country
United States
Facility Name
Providence Portland Medical Center
City
Portland
State/Province
Oregon
ZIP/Postal Code
97213
Country
United States
Facility Name
Hematology & Oncology Associates of Northeastern PA
City
Dunmore
State/Province
Pennsylvania
ZIP/Postal Code
18512
Country
United States
Facility Name
Penn State Milton S Hershey Medical Center
City
Hershey
State/Province
Pennsylvania
ZIP/Postal Code
17033
Country
United States
Facility Name
Lancaster General Hospital
City
Lancaster
State/Province
Pennsylvania
ZIP/Postal Code
17604
Country
United States
Facility Name
Hospital of the University of Pennsylvania Perelman Center for Advanced Medicine
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19104
Country
United States
Facility Name
University of Pennsylvania/Abramson Cancer Center
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19104
Country
United States
Facility Name
Pennsylvania Hospital
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19106
Country
United States
Facility Name
Thomas Jefferson University
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19107
Country
United States
Facility Name
Fox Chase Cancer Center
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19111
Country
United States
Facility Name
Allegheny General Hospital
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15212
Country
United States
Facility Name
UPMC MaGee Women's Hospital
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15213
Country
United States
Facility Name
University of Pittsburgh Cancer Institute- Hillman Cancer Center
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15232
Country
United States
Facility Name
Reading Hospital/McGlinn Cancer Institute
City
Wyomissing
State/Province
Pennsylvania
ZIP/Postal Code
19610
Country
United States
Facility Name
WellSpan Health York Cancer Center
City
York
State/Province
Pennsylvania
ZIP/Postal Code
17403
Country
United States
Facility Name
Rhode Island Hospital
City
Providence
State/Province
Rhode Island
ZIP/Postal Code
02903
Country
United States
Facility Name
Women & Infants Hospital of Rhode Island
City
Providence
State/Province
Rhode Island
ZIP/Postal Code
02905
Country
United States
Facility Name
Lexington Medical Center/Lexington Oncology Associates
City
Columbia
State/Province
South Carolina
ZIP/Postal Code
29169
Country
United States
Facility Name
Avera Cancer Institute-Aberdeen
City
Aberdeen
State/Province
South Dakota
ZIP/Postal Code
57401
Country
United States
Facility Name
Monument Health Rapid City Hospital
City
Rapid City
State/Province
South Dakota
ZIP/Postal Code
57701
Country
United States
Facility Name
Rapid City Regional Hospital/Regional Cancer Care Institute
City
Rapid City
State/Province
South Dakota
ZIP/Postal Code
57701
Country
United States
Facility Name
Avera Cancer Institute
City
Sioux Falls
State/Province
South Dakota
ZIP/Postal Code
57105
Country
United States
Facility Name
Vanderbilt University/Ingram Cancer Center
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37204
Country
United States
Facility Name
Nashville General Hospital at Meharry
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37208
Country
United States
Facility Name
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
Houston Methodist Hospital Cancer Center
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
MD Anderson Cancer Center
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
Doctors Hospital of Laredo
City
Laredo
State/Province
Texas
ZIP/Postal Code
78045
Country
United States
Facility Name
Huntsman Cancer Institute - University of Utah
City
Salt Lake City
State/Province
Utah
ZIP/Postal Code
84112
Country
United States
Facility Name
Inova Schar Cancer Institute
City
Fairfax
State/Province
Virginia
ZIP/Postal Code
22031
Country
United States
Facility Name
VCU Massey Cancer Center
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23298
Country
United States
Facility Name
CAMC Cancer Center
City
Charleston
State/Province
West Virginia
ZIP/Postal Code
25304
Country
United States
Facility Name
ThedaCare Regional Cancer Center
City
Appleton
State/Province
Wisconsin
ZIP/Postal Code
54913
Country
United States
Facility Name
HSHS Saint Vincent Hospital
City
Green Bay
State/Province
Wisconsin
ZIP/Postal Code
54301
Country
United States
Facility Name
Gunderson Lutheran Medical Center
City
La Crosse
State/Province
Wisconsin
ZIP/Postal Code
54601
Country
United States
Facility Name
University of Wisconsin Hospital and Clinics
City
Madison
State/Province
Wisconsin
ZIP/Postal Code
53792
Country
United States
Facility Name
Wheaton Franciscan Healthcare - St. Joseph
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53210
Country
United States
Facility Name
Columbia St. Mary's Water Tower Medical Commons
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53711
Country
United States
Facility Name
Wheaton Franciscan Healthcare-All Saints
City
Racine
State/Province
Wisconsin
ZIP/Postal Code
53405
Country
United States
Facility Name
Orchard Healthcare Research Inc.
City
Waukesha
State/Province
Wisconsin
ZIP/Postal Code
53188
Country
United States
Facility Name
UW Cancer Center at ProHealth Care
City
Waukesha
State/Province
Wisconsin
ZIP/Postal Code
53188
Country
United States
Facility Name
Wheaton Franciscan Healthcare - Wauwatosa
City
Wauwatosa
State/Province
Wisconsin
ZIP/Postal Code
53226
Country
United States
Facility Name
Southern Highlands Cancer Centre
City
Bowral
State/Province
New South Wales
ZIP/Postal Code
2576
Country
Australia
Facility Name
Coffs Harbour Health Campus - MNCCI
City
Coffs Harbour
State/Province
New South Wales
ZIP/Postal Code
2450
Country
Australia
Facility Name
The Breast & Endocrine Centre
City
Gateshead
State/Province
New South Wales
ZIP/Postal Code
2290
Country
Australia
Facility Name
Gosford Hospital
City
Gosford
State/Province
New South Wales
ZIP/Postal Code
2500
Country
Australia
Facility Name
Macquarie University Hospital
City
Macquarie Park
State/Province
New South Wales
ZIP/Postal Code
2109
Country
Australia
Facility Name
Orange Health Service
City
Orange
State/Province
New South Wales
ZIP/Postal Code
2800
Country
Australia
Facility Name
Wollongong Hospital
City
Wollongong
State/Province
New South Wales
ZIP/Postal Code
2500
Country
Australia
Facility Name
Royal Brisbane & Women's Hospital
City
Brisbane
State/Province
Queensland
ZIP/Postal Code
4029
Country
Australia
Facility Name
Flinders Drive
City
Bedford Park
State/Province
South Australia
ZIP/Postal Code
5042
Country
Australia
Facility Name
Royal Hobart Hospital
City
Hobart
State/Province
Tasmania
ZIP/Postal Code
7000
Country
Australia
Facility Name
The Northern Hospital
City
Epping
State/Province
Victoria
ZIP/Postal Code
3076
Country
Australia
Facility Name
St Vincent's Hospital
City
Fitzroy
State/Province
Victoria
ZIP/Postal Code
3065
Country
Australia
Facility Name
Peninsula Health - Frankston Hospital
City
Frankston
State/Province
Victoria
ZIP/Postal Code
3199
Country
Australia
Facility Name
University Hospital, Geelong
City
Geelong
State/Province
Victoria
ZIP/Postal Code
3220
Country
Australia
Facility Name
Peter MacCallum Cancer Centre
City
Melbourne
State/Province
Victoria
ZIP/Postal Code
3000
Country
Australia
Facility Name
Peninsula Health - Frankston Hospital
City
Melbourne
State/Province
Victoria
Country
Australia
Facility Name
Western Health, Sunshine Hospital
City
St. Albans
State/Province
Victoria
ZIP/Postal Code
3021
Country
Australia
Facility Name
South West Healthcare, Warrnambool
City
Warrnambool
State/Province
Victoria
ZIP/Postal Code
3280
Country
Australia
Facility Name
St John of God Bunbury Hospital
City
Bunbury
State/Province
Western Australia
ZIP/Postal Code
6231
Country
Australia
Facility Name
Fiona Stanley Hospital
City
Murdoch
State/Province
Western Australia
Country
Australia
Facility Name
Breast Cancer Research Centre - WA
City
Nedlands
State/Province
Western Australia
ZIP/Postal Code
6009
Country
Australia
Facility Name
LKH Feldkirch, Department of Internal Medicine
City
Feldkirch
ZIP/Postal Code
6807
Country
Austria
Facility Name
LKH Univ Klinikum Graz, Dept of Internal Med. and Oncology
City
Graz
ZIP/Postal Code
8036
Country
Austria
Facility Name
Medical University of Graz, Gyn. Dept.
City
Graz
ZIP/Postal Code
8036
Country
Austria
Facility Name
University Hospital Innsbruck, Department of Obstetrics and Gynaecology
City
Innsbruck
ZIP/Postal Code
6020
Country
Austria
Facility Name
BKH Kufstein, Innere Medizin
City
Kufstein
ZIP/Postal Code
6330
Country
Austria
Facility Name
LKH Hochsteiermark Leoben
City
Leoben
ZIP/Postal Code
8700
Country
Austria
Facility Name
Hospital of the Sisters of Charity Linz, Surg. Dept., Breast Health Center
City
Linz
ZIP/Postal Code
4010
Country
Austria
Facility Name
Kepler Universitätsklinikum Med. Campus III
City
Linz
ZIP/Postal Code
4020
Country
Austria
Facility Name
Weinviertelklinikum Mistelbach, Department of Surgery
City
Mistelbach
ZIP/Postal Code
2130
Country
Austria
Facility Name
BHS Ried, Abt. f. Gynäkologie
City
Ried
ZIP/Postal Code
4910
Country
Austria
Facility Name
LKH Salzburg, Univ. Klinik f. Innere Med. III
City
Salzburg
ZIP/Postal Code
5020
Country
Austria
Facility Name
Universitätsklinikum St. Pölten, Innere Medizin
City
St. Pölten
ZIP/Postal Code
3100
Country
Austria
Facility Name
Breast Centre Dr. Wette Viktor
City
St. Veit an der Glan
ZIP/Postal Code
9300
Country
Austria
Facility Name
Phyrn-Eisenwurzen Klinikum Steyr
City
Steyr
ZIP/Postal Code
4400
Country
Austria
Facility Name
Medical University of Vienna Department of Obstetrics and Gynaecology
City
Vienna
ZIP/Postal Code
1090
Country
Austria
Facility Name
Medical University Vienna - Coop Group Surgery/Oncology
City
Vienna
ZIP/Postal Code
1090
Country
Austria
Facility Name
Hospital Hietzing, Gynecology
City
Vienna
ZIP/Postal Code
1130
Country
Austria
Facility Name
St. Josef Krankenhaus, Department of Internal I
City
Vienna
ZIP/Postal Code
1130
Country
Austria
Facility Name
Klinik Ottakring
City
Vienna
ZIP/Postal Code
1160
Country
Austria
Facility Name
Salzkammergut-Klinikum Vöcklabruck
City
Voecklabruck
ZIP/Postal Code
4840
Country
Austria
Facility Name
Brustordination Dr. Thiel
City
Weiz
ZIP/Postal Code
8160
Country
Austria
Facility Name
Klinikum Wels - Grieskirchen GmbH, Department of Internal Medicine IV
City
Wels
ZIP/Postal Code
4600
Country
Austria
Facility Name
LKH Wolfsberg, Department of Surgery
City
Wolfsberg
ZIP/Postal Code
9400
Country
Austria
Facility Name
Landesklinikum Wr. Neustadt, Department of Surgery
City
Wr. Neustadt
ZIP/Postal Code
2700
Country
Austria
Facility Name
OLV ziekenhuis Aalst/Radiotherapy-Oncology
City
Aalst
ZIP/Postal Code
9300
Country
Belgium
Facility Name
CHU Saint Pierre/Medical Oncology
City
Brussels
ZIP/Postal Code
1000
Country
Belgium
Facility Name
Institut Jules Bordet/Medical Oncology Department
City
Brussels
ZIP/Postal Code
1000
Country
Belgium
Facility Name
Cliniques Universitaires Saint-Luc, Oncologisch centrum
City
Bruxelles
ZIP/Postal Code
1200
Country
Belgium
Facility Name
Grand Hopital de Charleroi - Oncologie-hématologie
City
Charleroi
ZIP/Postal Code
6000
Country
Belgium
Facility Name
University Hospital Antwerp (UZA)
City
Edegem
ZIP/Postal Code
2650
Country
Belgium
Facility Name
UZ Leuven/ Gynaecologie-Oncologie
City
Leuven
ZIP/Postal Code
3000
Country
Belgium
Facility Name
CHC - Saint-Joseph/Oncology-Hematology
City
Liège
ZIP/Postal Code
4000
Country
Belgium
Facility Name
CHU Sart Tilman Liège (Medical Oncology)
City
Liège
ZIP/Postal Code
4000
Country
Belgium
Facility Name
Clinique et Maternite Sainte-Elisabeth - Oncology Department
City
Namur
ZIP/Postal Code
5000
Country
Belgium
Facility Name
CHR - Centre Hospitalier Peltzer La Tourelle/ Oncology Department
City
Verviers
ZIP/Postal Code
4800
Country
Belgium
Facility Name
GZA Ziekenhuizen (Campus Sint-Augustinus) / Oncologische Centrum
City
Wilrijk
ZIP/Postal Code
2610
Country
Belgium
Facility Name
Tom Baker Cancer Centre - Dept. of Oncology
City
Calgary
State/Province
Alberta
ZIP/Postal Code
T2N4N2
Country
Canada
Facility Name
BC Cancer Agency- Abbotsford Centre
City
Abbotsford
State/Province
British Columbia
ZIP/Postal Code
V2S0C2
Country
Canada
Facility Name
BC Cancer Agency - Sindi Ahluwalia Hawkins Centre for the Southern Interior
City
Kelowna
State/Province
British Columbia
ZIP/Postal Code
V1Y5L3
Country
Canada
Facility Name
BC Cancer Agency - Vancouver Cancer Centre
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z4E6
Country
Canada
Facility Name
CancerCare Manitoba - St. Boniface Hospital
City
Winnipeg
State/Province
Manitoba
ZIP/Postal Code
R2H2A6
Country
Canada
Facility Name
The Vitalite Health Network - Dr. Leon Richard
City
Moncton
State/Province
New Brunswick
ZIP/Postal Code
E1C8X3
Country
Canada
Facility Name
Horizon Health Network - Saint John Regional Hospital
City
Saint John
State/Province
New Brunswick
ZIP/Postal Code
E2L4L4
Country
Canada
Facility Name
Queen Elizabeth II Health Sciences Centre
City
Halifax
State/Province
Nova Scotia
ZIP/Postal Code
B3H2Y9
Country
Canada
Facility Name
Juravinski Cancer Centre
City
Hamilton
State/Province
Ontario
ZIP/Postal Code
L8V5C2
Country
Canada
Facility Name
Kingston General Hospital, Cancer Centre of Southeastern Ontario/Oncology
City
Kingston
State/Province
Ontario
ZIP/Postal Code
K7L5P9
Country
Canada
Facility Name
Grand River Regional Cancer Center
City
Kitchener
State/Province
Ontario
ZIP/Postal Code
N2G1G3
Country
Canada
Facility Name
Niagara Health System
City
St. Catharines
State/Province
Ontario
ZIP/Postal Code
L2S0A9
Country
Canada
Facility Name
Sunnybrook
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M4N3M
Country
Canada
Facility Name
University Health Network Princess Margaret Cancer Centre
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5G1X5
Country
Canada
Facility Name
The Jewish General Hospital
City
Montréal
State/Province
Quebec
ZIP/Postal Code
H2L4M1
Country
Canada
Facility Name
CHUM Hôtel Dieu
City
Montréal
State/Province
Quebec
ZIP/Postal Code
H2W1T8
Country
Canada
Facility Name
CHU de Québec - Hôpital du St Sacrement
City
Québec
State/Province
Quebec
ZIP/Postal Code
G1S4L8
Country
Canada
Facility Name
Allan Blair Cancer Centre
City
Regina
State/Province
Saskatchewan
ZIP/Postal Code
S4T7TI
Country
Canada
Facility Name
Saskatoon Cancer Center, University of Saskatchewan
City
Saskatoon
State/Province
Saskatchewan
ZIP/Postal Code
S7N4H4
Country
Canada
Facility Name
University Hospital Aachen
City
Aachen
ZIP/Postal Code
52074
Country
Germany
Facility Name
Praxisklinik Krebsheilkunde für Frauen
City
Berlin
ZIP/Postal Code
10367
Country
Germany
Facility Name
Helios Klinikum Berlin-Buch
City
Berlin
ZIP/Postal Code
13125
Country
Germany
Facility Name
Studienzentrum City
City
Berlin
ZIP/Postal Code
14169
Country
Germany
Facility Name
Marienhospital Bottrop, Klinik für Gynäkologie und Geburtshilfe
City
Bottrop
ZIP/Postal Code
46236
Country
Germany
Facility Name
Studien GbR Braunschweig, Lorenz&HeckerWesche
City
Braunschweig
ZIP/Postal Code
38100
Country
Germany
Facility Name
Praxis und Tagesklinik für gynäkologische Onkologie,
City
Ebersberg
ZIP/Postal Code
85560
Country
Germany
Facility Name
MVZ Eggenfelden
City
Eggenfelden
ZIP/Postal Code
84307
Country
Germany
Facility Name
Frauenklinik/University Hospital Erlangen
City
Erlangen
ZIP/Postal Code
91054
Country
Germany
Facility Name
Centrum für Hämatologie und Onkologie Bethanien
City
Frankfurt
ZIP/Postal Code
60389
Country
Germany
Facility Name
Agaplesion Markus Krankenhaus
City
Frankfurt
ZIP/Postal Code
60431
Country
Germany
Facility Name
Klinikum Frankfurt Höchst
City
Frankfurt
ZIP/Postal Code
65929
Country
Germany
Facility Name
Onkol. GP Dres. med. Wilke/Wagner/Petzoldt
City
Fürth
ZIP/Postal Code
90766
Country
Germany
Facility Name
Universitätsfrauenklinik Halle (Saale)
City
Halle (Saale)
ZIP/Postal Code
'06120
Country
Germany
Facility Name
University Medical Center Hamburg-Eppendorf, Department of Gynecology
City
Hamburg
ZIP/Postal Code
20246
Country
Germany
Facility Name
Albertinen Krankenhaus
City
Hamburg
ZIP/Postal Code
22457
Country
Germany
Facility Name
Städtisches Klinikum Karlsruhe
City
Karlsruhe
ZIP/Postal Code
76133
Country
Germany
Facility Name
Elisabeth Krankenhaus Kassel Brustzentrum
City
Kassel
ZIP/Postal Code
34125
Country
Germany
Facility Name
St. Elisabeth Krankenhaus Leipzig
City
Leipzig
ZIP/Postal Code
04277
Country
Germany
Facility Name
St. Vincenz KH Limburg Frauenklinik
City
Limburg
ZIP/Postal Code
65549
Country
Germany
Facility Name
UKSH Campus Lübeck, Klinik für Frauenheilkunde und Geburtshilfe
City
Lübeck
ZIP/Postal Code
23538
Country
Germany
Facility Name
Universitätsmedizin Mainz
City
Mainz
ZIP/Postal Code
55131
Country
Germany
Facility Name
Praxis Gynäkologie Arabella
City
München
ZIP/Postal Code
81925
Country
Germany
Facility Name
University Clinic Oldenburg
City
Oldenburg
ZIP/Postal Code
26133
Country
Germany
Facility Name
Oncologianova GmbH
City
Recklinghausen
ZIP/Postal Code
45657
Country
Germany
Facility Name
HELIOS Klinik Rottweil - Gynäkologie
City
Rottweil
ZIP/Postal Code
78628
Country
Germany
Facility Name
St. Josefs-Hospital
City
Wiesbaden
ZIP/Postal Code
65189
Country
Germany
Facility Name
Országos Onkológiai Intézet - "B" Belgyógyászati Onkológiai és Klinikai Farmakológiai Osztály
City
Budapest
ZIP/Postal Code
1122
Country
Hungary
Facility Name
Uzsoki Utcai Kórház - Onkoradiológia, Sugárterápia, Fővárosi Onkoradiológiai Központ
City
Budapest
ZIP/Postal Code
1145
Country
Hungary
Facility Name
University of Debrecen Medical Center, Clinic of Oncology
City
Debrecen
ZIP/Postal Code
4032
Country
Hungary
Facility Name
Petz Aladár Megyei Oktatókórház - Onkoradiológiai Osztály
City
Győr
ZIP/Postal Code
9023
Country
Hungary
Facility Name
Szegedi Tudomanyegyetem Általános Orvostudományi Kar Szent-Györgyi Albert Klinikai Központ, Onkoterápiás Klinika
City
Szeged
ZIP/Postal Code
6720
Country
Hungary
Facility Name
Bon Secours Hospital, Cork
City
Cork
Country
Ireland
Facility Name
Cork University Hospital, Oncology Clinical Trials Unit
City
Cork
Country
Ireland
Facility Name
Beaumont Hospital - Cancer Clinical Trials Unit
City
Dublin
Country
Ireland
Facility Name
Mater Misericordiae University Hospital
City
Dublin
Country
Ireland
Facility Name
St James's Hospital, Cancer Clinical Trials Office, Old Admin Building,
City
Dublin
Country
Ireland
Facility Name
St Vincent Hospital - Medical Oncology Research Department
City
Dublin
Country
Ireland
Facility Name
University Hospital Limerick, Midwestern Cancer Centre
City
Limerick
Country
Ireland
Facility Name
Sligo University Hospital
City
Sligo
Country
Ireland
Facility Name
University Hospital Waterford, Cancer Research Department
City
Waterford
Country
Ireland
Facility Name
Rabin Medical Center (RMC)
City
Petah Tikva
State/Province
Central
ZIP/Postal Code
49100
Country
Israel
Facility Name
Sheba Medical Center Tel Hashomer
City
Ramat Gan
State/Province
Tel Aviv
ZIP/Postal Code
52621
Country
Israel
Facility Name
Sourasky Medical Center
City
Tel-Aviv
ZIP/Postal Code
64239
Country
Israel
Facility Name
Azienda Ospedaliero-Universitaria di Ferrara
City
Ferrara
ZIP/Postal Code
44124
Country
Italy
Facility Name
Azienda Ospedaliero-Universitaria Careggi/Florence University/Radiation Oncology Unit
City
Florence
ZIP/Postal Code
50134
Country
Italy
Facility Name
Department of Internal Medicine (DIMI) - IRCCS San Martino University Hospital
City
Genoa
ZIP/Postal Code
16132
Country
Italy
Facility Name
P.O. Misericordia AUSL Toscana Sud Est
City
Grosseto
ZIP/Postal Code
58100
Country
Italy
Facility Name
Ospedale "Mater Salutis" di Legnago, Dept. of Medical Oncology
City
Legnago
ZIP/Postal Code
37045
Country
Italy
Facility Name
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.) IRCCS
City
Meldola
ZIP/Postal Code
47014
Country
Italy
Facility Name
Ospedale San Raffaele
City
Milano
ZIP/Postal Code
20132
Country
Italy
Facility Name
Istituto Europeo di Oncologia
City
Milano
ZIP/Postal Code
20141
Country
Italy
Facility Name
Policlinico di Monza - Istituto di Oncologia del Policlinico di Monza
City
Monza
ZIP/Postal Code
20900
Country
Italy
Facility Name
Medical Oncology Unit; University Hospital of Parma (Azienda Ospedaliero-Universitaria di Parma)
City
Parma
ZIP/Postal Code
43100
Country
Italy
Facility Name
Nuovo Ospedale di Prato (NOP) - Azienda USL4 Prato
City
Prato
ZIP/Postal Code
59100
Country
Italy
Facility Name
ASST Bergamo Ovest
City
Treviglio
ZIP/Postal Code
24047
Country
Italy
Facility Name
S. Anna Hospital (Ospedale Sant'Anna)- Turin
City
Turin
ZIP/Postal Code
10126
Country
Italy
Facility Name
Nagoya City University Hospital/Dept. of Breast & Endocrine Surgery
City
Nagoya
State/Province
Aichi
ZIP/Postal Code
467-8601
Country
Japan
Facility Name
Department of Breast Surgery National Hospital Organization Hokkaido Cancer Center
City
Sapporo
State/Province
Hokkaido
ZIP/Postal Code
003-0804
Country
Japan
Facility Name
Chiba Cancer Center
City
Chiba
ZIP/Postal Code
260-8717
Country
Japan
Facility Name
Kyoto University Hospital/Breast Surgery
City
Kyoto
ZIP/Postal Code
606-8507
Country
Japan
Facility Name
National Hospital Organization Osaka National Hospital
City
Osaka
ZIP/Postal Code
540-0006
Country
Japan
Facility Name
Osaka International Cancer Institute
City
Osaka
ZIP/Postal Code
541-8567
Country
Japan
Facility Name
Seoul National University Hospital, Hematology-Medical Oncology
City
Seoul
ZIP/Postal Code
03080
Country
Korea, Republic of
Facility Name
Severance Hospital Medical Doctor at Department of Medical Oncology
City
Seoul
ZIP/Postal Code
03722
Country
Korea, Republic of
Facility Name
Samsung Medical Centre, Breast Cancer Center, Department of Medicine, Division of Hematology/Oncology
City
Seoul
ZIP/Postal Code
06351
Country
Korea, Republic of
Facility Name
Centro Médico Zambrano Hellion
City
Monterrey
State/Province
Nuevo León
ZIP/Postal Code
66278
Country
Mexico
Facility Name
Centro Oncológico Estatal ISSEMYM
City
Toluca de Lerdo
State/Province
Toluca
ZIP/Postal Code
50180
Country
Mexico
Facility Name
National Cancer Institute Mexico, Breast Cancer Department
City
Mexico City
ZIP/Postal Code
14080
Country
Mexico
Facility Name
Hagaziekenhuis
City
Den Haag
ZIP/Postal Code
2545 AA
Country
Netherlands
Facility Name
Máxima Medisch Centrum
City
Eindhoven
ZIP/Postal Code
5631 BM
Country
Netherlands
Facility Name
Zuyderland Ziekenhuis, Oncology
City
Geleen
ZIP/Postal Code
6162 BG
Country
Netherlands
Facility Name
St Antonius Hospital
City
Nieuwegein
ZIP/Postal Code
3435 CM
Country
Netherlands
Facility Name
Zaans Medical Center
City
Zaandam
ZIP/Postal Code
1502 DV
Country
Netherlands
Facility Name
Isala, Dept of Medical Oncology
City
Zwolle
ZIP/Postal Code
8025 AB
Country
Netherlands
Facility Name
Uniwersyteckie Centrum Kliniczne (UCK), Klinika Onkologii I Radioterapii
City
Gdansk
ZIP/Postal Code
80-952
Country
Poland
Facility Name
Opolskie Centrum Onkologii, Oddzial Onkologii Klinicznej
City
Opole
ZIP/Postal Code
45-001
Country
Poland
Facility Name
Klinika Nowotworów Piersi i Chirurgii Rekonstrukcyjnej, Centrum Onkologii-Instytut im. Marii Skłodowskiej-Curie
City
Warsaw
ZIP/Postal Code
02-781
Country
Poland
Facility Name
Instytut MSF Spółka z ograniczoną odpowiedzialnością
City
Łódź
Country
Poland
Facility Name
Instituto Português de Oncologia (IPO) de Lisboa Francisco Gentil
City
Lisboa
ZIP/Postal Code
1099-023
Country
Portugal
Facility Name
Hospital da Luz
City
Lisboa
ZIP/Postal Code
1500-650
Country
Portugal
Facility Name
CUF Descobertas Hospital, Hemato-Oncologia
City
Lisboa
ZIP/Postal Code
1998-018
Country
Portugal
Facility Name
Centro Clinico Champalimaud
City
Lisbon
ZIP/Postal Code
1400-038
Country
Portugal
Facility Name
Instituto Português de Oncologia (IPO) Francisco Gentil do Porto
City
Porto
ZIP/Postal Code
4200
Country
Portugal
Facility Name
Complejo Hospitalario Universitario A Coruña (CHUAC)
City
A Coruña
ZIP/Postal Code
15006
Country
Spain
Facility Name
Centro Oncologico de Galicia
City
A Coruña
ZIP/Postal Code
15009
Country
Spain
Facility Name
Hospital General Universitario Alicante
City
Alicante
ZIP/Postal Code
03010
Country
Spain
Facility Name
ICO Badalona
City
Badalona
ZIP/Postal Code
08916
Country
Spain
Facility Name
Hospital del Mar
City
Barcelona
ZIP/Postal Code
08003
Country
Spain
Facility Name
Hospital Universitari Quirón Dexeus
City
Barcelona
ZIP/Postal Code
08028
Country
Spain
Facility Name
Hospital Clinic Barcelona
City
Barcelona
ZIP/Postal Code
08036
Country
Spain
Facility Name
Hospital General de Granollers
City
Barcelona
ZIP/Postal Code
08402
Country
Spain
Facility Name
Instituto Catalán de Oncología (ICO) de L'Hospitalet de Llobregat
City
Barcelona
ZIP/Postal Code
08908
Country
Spain
Facility Name
Hospital Vall d´Hebron
City
Barcelona
ZIP/Postal Code
8035
Country
Spain
Facility Name
Hospital Universitario de Burgos
City
Burgos
ZIP/Postal Code
09006
Country
Spain
Facility Name
Consorcio Hospitalario Provincial de Castellon
City
Castellón De La Plana
ZIP/Postal Code
12002
Country
Spain
Facility Name
San Pedro de Alcántara
City
Cáceres
ZIP/Postal Code
10003
Country
Spain
Facility Name
Hospital Reina Sofía
City
Córdoba
ZIP/Postal Code
14004
Country
Spain
Facility Name
Hospital General Universitario de Elche
City
Elche
ZIP/Postal Code
03203
Country
Spain
Facility Name
ICO/ H. Josep Trueta
City
Girona
ZIP/Postal Code
17007
Country
Spain
Facility Name
Complejo asistencial universitario de Leon
City
León
ZIP/Postal Code
24001
Country
Spain
Facility Name
Hospital Universitario Gregorio Marañón
City
Madrid
ZIP/Postal Code
28007
Country
Spain
Facility Name
MD Anderson Cancer Center
City
Madrid
ZIP/Postal Code
28033
Country
Spain
Facility Name
Hospital Universitario Ramon y Cajal
City
Madrid
ZIP/Postal Code
28034
Country
Spain
Facility Name
Fundación Jiménez Díaz
City
Madrid
ZIP/Postal Code
28040
Country
Spain
Facility Name
Hospital Universitario 12 de Octubre
City
Madrid
ZIP/Postal Code
28041
Country
Spain
Facility Name
Hospital La Paz, Servicio de Oncologia Médica
City
Madrid
ZIP/Postal Code
28046
Country
Spain
Facility Name
CIOCC - Centro Integral Oncológico Clara Campal / Hospital HM Universitario Sanchinarro
City
Madrid
ZIP/Postal Code
28050
Country
Spain
Facility Name
Hospital Puerta de Hierro Majadahonda, Oncologia Médica
City
Madrid
ZIP/Postal Code
28222
Country
Spain
Facility Name
Hospital Universitario Fundacion Alcorcón
City
Madrid
ZIP/Postal Code
28922
Country
Spain
Facility Name
Hospital General Universitario José Mª Morales Meseguer
City
Murcia
ZIP/Postal Code
30008
Country
Spain
Facility Name
Hospital Clínico Universitario Virgen de la Arrixaca
City
Murcia
ZIP/Postal Code
30120
Country
Spain
Facility Name
Hospital Clínico Universitario Virgen de la Victoria
City
Málaga
ZIP/Postal Code
29010
Country
Spain
Facility Name
Hospital Universitario Central de Asturias
City
Oviedo
ZIP/Postal Code
33011
Country
Spain
Facility Name
Hospitali Universitari son Espases
City
Palma
ZIP/Postal Code
07120
Country
Spain
Facility Name
Hospital Son Llatzer
City
Palma
ZIP/Postal Code
07198
Country
Spain
Facility Name
Complejo Hospitalario de Navarra
City
Pamplona
ZIP/Postal Code
31008
Country
Spain
Facility Name
Hospital Universitari Sant Joan de Reus
City
Reus
ZIP/Postal Code
43204
Country
Spain
Facility Name
Hospital Universitario Donostia
City
San Sebastián
ZIP/Postal Code
20014
Country
Spain
Facility Name
Hospital de Sant Juan Despi Moisés Broggi
City
Sant Joan Despì
ZIP/Postal Code
08970
Country
Spain
Facility Name
Hospital Clinico Universitario de Santiago
City
Santiago
ZIP/Postal Code
15706
Country
Spain
Facility Name
Hospital Unversitario Virgen Macarena
City
Sevilla
ZIP/Postal Code
41009
Country
Spain
Facility Name
Hospital Quirón Sagrado Corazón
City
Sevilla
ZIP/Postal Code
41013
Country
Spain
Facility Name
Hospital Universitario Virgen del Rocio
City
Sevilla
ZIP/Postal Code
41013
Country
Spain
Facility Name
Consorci Sanitari de Terrassa
City
Terrassa
ZIP/Postal Code
08227
Country
Spain
Facility Name
Hospital Virgen de la Salud
City
Toledo
ZIP/Postal Code
45004
Country
Spain
Facility Name
Hospital Clínico Universitario de Valencia
City
Valencia
ZIP/Postal Code
46010
Country
Spain
Facility Name
Hosital Arnau de Vilanova Valencia
City
Valencia
ZIP/Postal Code
46015
Country
Spain
Facility Name
Hospital Clinico Universitario Lozano Blesa
City
Zaragoza
ZIP/Postal Code
50009
Country
Spain
Facility Name
Hospital Universitario Miguel Servet
City
Zaragoza
ZIP/Postal Code
50009
Country
Spain
Facility Name
Gävle Hospital, Dept. of Oncology
City
Gävle
ZIP/Postal Code
801 87
Country
Sweden
Facility Name
Sahlgrenska University Hospital, Dept. Oncology
City
Göteborg
ZIP/Postal Code
413 45
Country
Sweden
Facility Name
Karolinska Universitetssjukhuset, Bröstcentrum A2:00
City
Stockholm
ZIP/Postal Code
171 76
Country
Sweden
Facility Name
Akademiska Sjukhuset Uppsala (University Hospital), Onkologkliniken
City
Uppsala
ZIP/Postal Code
751 85
Country
Sweden
Facility Name
Universitetssjukhuset Örebro (University Hospital) Örebro, Onkologkliniken
City
Örebro
ZIP/Postal Code
701 85
Country
Sweden
Facility Name
Kantonspital Baden
City
Baden
State/Province
Aargau
ZIP/Postal Code
5404
Country
Switzerland
Facility Name
Spital STS AG, Onkologiezentrum Thun-Berner Oberland
City
Thun
State/Province
Bern
ZIP/Postal Code
3600
Country
Switzerland
Facility Name
Hôpitaux Universitaires de Genève
City
Genève
State/Province
Geneva
ZIP/Postal Code
1211
Country
Switzerland
Facility Name
Kantonsspital Graubünden
City
Chur
State/Province
Graubünden
ZIP/Postal Code
7000
Country
Switzerland
Facility Name
IOSI-Breast Cancer Unit-Ospedale San Giovanni-Bellinzona
City
Bellinzona
State/Province
Tessin
ZIP/Postal Code
6500
Country
Switzerland
Facility Name
Fondazione Oncologia Lago Maggiore, Locarno
City
Locarno
State/Province
Tessin
ZIP/Postal Code
6600
Country
Switzerland
Facility Name
Dep. Oncology, University Hospital
City
Basel
ZIP/Postal Code
4031
Country
Switzerland
Facility Name
HFR Fribourg, Oncology Department
City
Fribourg
ZIP/Postal Code
1708
Country
Switzerland
Facility Name
Luzerner Kantonsspital, Dept. of Medical Oncology
City
Luzern
ZIP/Postal Code
6000
Country
Switzerland
Facility Name
Onkologisches Forschungszentrum Klinik St. Anna, Hirslanden
City
Luzern
ZIP/Postal Code
6006
Country
Switzerland
Facility Name
Kantonsspital St.Gallen, Onkologie/Hämatologie
City
St.Gallen
ZIP/Postal Code
9007
Country
Switzerland
Facility Name
Brust-Zentrum Zürich
City
Zurich
ZIP/Postal Code
8008
Country
Switzerland
Facility Name
Universitätsspital Zürich, Klinik für Onkologie
City
Zurich
ZIP/Postal Code
8091
Country
Switzerland
Facility Name
Changhua Christian Hospital/General Surgery
City
Changhua
State/Province
Changhua County
ZIP/Postal Code
500
Country
Taiwan
Facility Name
Kaohsiung Medical University Hospital
City
Kaohsiung
ZIP/Postal Code
807
Country
Taiwan
Facility Name
National Cheng Kung University Hospital, Division of Hemato-Oncology, Dept. Internal Medicine
City
Tainan
ZIP/Postal Code
704
Country
Taiwan
Facility Name
National Taiwan University Hospital/Department of Surgery
City
Taipei
ZIP/Postal Code
100
Country
Taiwan
Facility Name
Taipei Veterans General Hospital/General Surgery
City
Taipei
ZIP/Postal Code
112
Country
Taiwan
Facility Name
City Hospital Birmingham
City
Birmingham
ZIP/Postal Code
B18 7QH
Country
United Kingdom
Facility Name
University Hospitals Bristol NHS Foundation Trust
City
Bristol
ZIP/Postal Code
BS2 8ED
Country
United Kingdom
Facility Name
Velindre Cancer Centre
City
Cardiff
ZIP/Postal Code
CF14 2TL
Country
United Kingdom
Facility Name
Royal Marsden Hospital Chelsea
City
Chelsea
ZIP/Postal Code
SW3 6JJ
Country
United Kingdom
Facility Name
The Beatson West of Scotland Cancer Centre
City
Glasgow
ZIP/Postal Code
G12 0YN
Country
United Kingdom
Facility Name
University Hospitals of Leicester
City
Leicester
ZIP/Postal Code
LE1 5WW
Country
United Kingdom
Facility Name
Royal Liverpool University Hospital
City
Liverpool
ZIP/Postal Code
L7 8XP
Country
United Kingdom
Facility Name
Guy's and St Thomas' NHS Foundation Trust
City
London
ZIP/Postal Code
SE1 7EH
Country
United Kingdom
Facility Name
The Royal Marsden Sutton
City
London
ZIP/Postal Code
SW3 6JJ
Country
United Kingdom
Facility Name
Charing Cross Hospital
City
London
ZIP/Postal Code
W6 8RF UK
Country
United Kingdom
Facility Name
Maidstone Hospital, Kent Oncology Centre
City
Maidstone
ZIP/Postal Code
ME16 9QQ
Country
United Kingdom
Facility Name
The Christie NHS Foundation Trust
City
Manchester
ZIP/Postal Code
M20 4BX
Country
United Kingdom
Facility Name
Northern Centre for Cancer Care
City
Newcastle upon Tyne
ZIP/Postal Code
NE7 7DN
Country
United Kingdom
Facility Name
Nottingham University Hospitals NHS TRUST UK
City
Nottingham
ZIP/Postal Code
NG5 1PB
Country
United Kingdom
Facility Name
Weston Park Hospital, Sheffield Teaching Hospitals
City
Sheffield
ZIP/Postal Code
S10 2SJ
Country
United Kingdom
Facility Name
Royal Cornwall Hospitals NHS Trust, Oncology Trials, Sunrise Centre
City
Truro
ZIP/Postal Code
TR1 3LQ
Country
United Kingdom
12. IPD Sharing Statement
Citations:
PubMed Identifier
34995105
Citation
Mayer EL, Fesl C, Hlauschek D, Garcia-Estevez L, Burstein HJ, Zdenkowski N, Wette V, Miller KD, Balic M, Mayer IA, Cameron D, Winer EP, Ponce Lorenzo JJ, Lake D, Pristauz-Telsnigg G, Haddad TC, Shepherd L, Iwata H, Goetz M, Cardoso F, Traina TA, Sabanathan D, Breitenstein U, Ackerl K, Metzger Filho O, Zehetner K, Solomon K, El-Abed S, Theall KP, Lu DR, Dueck A, Gnant M, DeMichele A. Treatment Exposure and Discontinuation in the PALbociclib CoLlaborative Adjuvant Study of Palbociclib With Adjuvant Endocrine Therapy for Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer (PALLAS/AFT-05/ABCSG-42/BIG-14-03). J Clin Oncol. 2022 Feb 10;40(5):449-458. doi: 10.1200/JCO.21.01918. Epub 2022 Jan 7.
Results Reference
derived
PubMed Identifier
34874182
Citation
Gnant M, Dueck AC, Frantal S, Martin M, Burstein HJ, Greil R, Fox P, Wolff AC, Chan A, Winer EP, Pfeiler G, Miller KD, Colleoni M, Suga JM, Rubovsky G, Bliss JM, Mayer IA, Singer CF, Nowecki Z, Hahn O, Thomson J, Wolmark N, Amillano K, Rugo HS, Steger GG, Hernando Fernandez de Aranguiz B, Haddad TC, Perello A, Bellet M, Fohler H, Metzger Filho O, Jallitsch-Halper A, Solomon K, Schurmans C, Theall KP, Lu DR, Tenner K, Fesl C, DeMichele A, Mayer EL; PALLAS groups and investigators. Adjuvant Palbociclib for Early Breast Cancer: The PALLAS Trial Results (ABCSG-42/AFT-05/BIG-14-03). J Clin Oncol. 2022 Jan 20;40(3):282-293. doi: 10.1200/JCO.21.02554. Epub 2021 Dec 7.
Results Reference
derived
PubMed Identifier
33460574
Citation
Mayer EL, Dueck AC, Martin M, Rubovszky G, Burstein HJ, Bellet-Ezquerra M, Miller KD, Zdenkowski N, Winer EP, Pfeiler G, Goetz M, Ruiz-Borrego M, Anderson D, Nowecki Z, Loibl S, Moulder S, Ring A, Fitzal F, Traina T, Chan A, Rugo HS, Lemieux J, Henao F, Lyss A, Antolin Novoa S, Wolff AC, Vetter M, Egle D, Morris PG, Mamounas EP, Gil-Gil MJ, Prat A, Fohler H, Metzger Filho O, Schwarz M, DuFrane C, Fumagalli D, Theall KP, Lu DR, Bartlett CH, Koehler M, Fesl C, DeMichele A, Gnant M. Palbociclib with adjuvant endocrine therapy in early breast cancer (PALLAS): interim analysis of a multicentre, open-label, randomised, phase 3 study. Lancet Oncol. 2021 Feb;22(2):212-222. doi: 10.1016/S1470-2045(20)30642-2. Epub 2021 Jan 15.
Results Reference
derived
PubMed Identifier
30032196
Citation
Dieras V, Rugo HS, Schnell P, Gelmon K, Cristofanilli M, Loi S, Colleoni M, Lu DR, Mori A, Gauthier E, Huang Bartlett C, Slamon DJ, Turner NC, Finn RS. Long-term Pooled Safety Analysis of Palbociclib in Combination With Endocrine Therapy for HR+/HER2- Advanced Breast Cancer. J Natl Cancer Inst. 2019 Apr 1;111(4):419-430. doi: 10.1093/jnci/djy109.
Results Reference
derived
Learn more about this trial
PALbociclib CoLlaborative Adjuvant Study
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