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Stimulus-response and Parkinson's Disease (SRlearning) (SRlearning)

Primary Purpose

Parkinson's Disease

Status
Terminated
Phase
Not Applicable
Locations
France
Study Type
Interventional
Intervention
Stimulus-response
Sponsored by
Fondation Ophtalmologique Adolphe de Rothschild
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional basic science trial for Parkinson's Disease

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • Patient : Parkinson's disease Controls: healthy volunteers paired to patients on sex and age group

Exclusion Criteria:

  • Other neurological condition
  • Known pregnancy or breastfeeding woman
  • No medical insurance coverage
  • Person under legal protection

Sites / Locations

  • Fondation Ophtalmologique A. de Rothschild

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Other

Arm Label

Parkinson's disease

Controls

Arm Description

Parkinson's disease patients

Healthy volunteers paired with Parkinson's disease patients on sex and age group, whose data will be extracted from a CNRS existing database

Outcomes

Primary Outcome Measures

Reaction time (second)

Secondary Outcome Measures

Full Information

First Posted
July 30, 2015
Last Updated
December 20, 2019
Sponsor
Fondation Ophtalmologique Adolphe de Rothschild
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1. Study Identification

Unique Protocol Identification Number
NCT02515136
Brief Title
Stimulus-response and Parkinson's Disease (SRlearning)
Acronym
SRlearning
Official Title
Stimulus-response Associations in Parkinson's Disease Patients
Study Type
Interventional

2. Study Status

Record Verification Date
December 2019
Overall Recruitment Status
Terminated
Study Start Date
July 1, 2015 (Actual)
Primary Completion Date
January 2018 (Actual)
Study Completion Date
January 2018 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Fondation Ophtalmologique Adolphe de Rothschild

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
In a computerized experiment, visual stimuli will be presented to the parkinson's disease patients and to the controls. They will respond to each image by acting on the keyboard in a specific manner. Each participant will repeat that task 384 times per session. A break will be inserted every 12 tests so that participants can rest. The experiment consists of three sessions. Each image will be presented three times. For the first two presentations it is assumed that a link will be created between the image and the task, and the image and action. In the third presentation, the same task and the same action will be maintained or will be swapped. In this way, It can be checked whether associations thus generated will affect the performance of the participants when tasks and actions will be incongruent.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Parkinson's Disease

7. Study Design

Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
100 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Parkinson's disease
Arm Type
Experimental
Arm Description
Parkinson's disease patients
Arm Title
Controls
Arm Type
Other
Arm Description
Healthy volunteers paired with Parkinson's disease patients on sex and age group, whose data will be extracted from a CNRS existing database
Intervention Type
Behavioral
Intervention Name(s)
Stimulus-response
Intervention Description
See summary
Primary Outcome Measure Information:
Title
Reaction time (second)
Time Frame
immediate

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: Patient : Parkinson's disease Controls: healthy volunteers paired to patients on sex and age group Exclusion Criteria: Other neurological condition Known pregnancy or breastfeeding woman No medical insurance coverage Person under legal protection
Facility Information:
Facility Name
Fondation Ophtalmologique A. de Rothschild
City
Paris
ZIP/Postal Code
75019
Country
France

12. IPD Sharing Statement

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Stimulus-response and Parkinson's Disease (SRlearning)

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