Comparison of LCBDE vs ERCP + LC for Choledocholithiasis
Choledocholithiasis
About this trial
This is an interventional treatment trial for Choledocholithiasis focused on measuring Cholangiopancreatography, Endoscopic, Common bile duct, Complication, Recurrence, Laparoscopic
Eligibility Criteria
Inclusion Criteria:
- Age 18-65 years old
- Choledocholithiasis patient did not perform any operation
- Common bile duct stone less than 2cm in maximum diameter
Exclusion Criteria:
- Unwillingness or inability to consent for the study
- Coagulation dysfunction (INR> 1.3) and low peripheral blood platelet count (<50×109 / L) or using anti-coagulation drugs
- Previous EST, EPBD or percutaneous transhepatic biliary drainage (PTBD)
- Prior surgery of Bismuth Ⅱ and Roux-en-Y
- Benign or malignant CBD stricture
- Preoperative coexistent diseases: acute pancreatitis, GI tract hemorrhage, severe liver disease, primary sclerosing cholangitis (PSC), septic shock
- Combined with Mirizzi syndrome and intrahepatic bile duct stones
- Malignancies
- Biliary-duodenal fistula confirmed during ERCP
- Pregnant women
Sites / Locations
- The first hospital of Lanzhou UniversityRecruiting
- Union hospital,Tongji medical collage,Huazhong University of science and technologyRecruiting
- Second Xiangya Hospital, Central South UniversityRecruiting
- The First Hospital of Jilin UniversityRecruiting
- General Hospital of Ningxia Medical UniversityRecruiting
- Shandong jiaotong HospitalRecruiting
- The first affiliated hospital of Xi 'an jiaotong universityRecruiting
- The First Teaching Hospital of Xinjiang Medical UniversityRecruiting
- The First Affiliated Hospital, Zhejiang UniversityRecruiting
- Southwest Hospital of Third Military Medical UniversityRecruiting
- Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineRecruiting
- Tianjin Nankai HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
LCBDE group (single step)
ERCP group (sequential step)
Choledocholithiasis patient, after Laparoscopic Cholecystectomy (LC) to remove the gallbladder, Laparoscopic Common Bile Duct Exploration (LCBDE) was performed for removing the bile duct stone(s) in laparoscopy. Choledochoscope detection or cholangiograms should be chosen as a method of obtain stone clearance. T-tube was acceptable if needed.
Choledocholithiasis patient, Endoscopic Retrograde cholangiopancreatography (ERCP) was performed for removing the bile duct stone(s) in endoscopy prior to Laparoscopic Cholecystectomy (LC). Sphincterotomy (EST) and Endoscopic papillary balloon dilatation (EPBD) can be chosen accordingly. The laparoscopic cholecystectomy was subsequently performed as soon as technically feasible following the ERCP in one month.