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Strength Training for Elderlies and Their Effects on Muscle Fatigue and Microcirculation - Randomized Clinical Trial

Primary Purpose

Aging

Status
Completed
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Strength training program
Sponsored by
Professor Fernando Figueira Integral Medicine Institute
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional basic science trial for Aging focused on measuring Microcirculation, Electromyography, Motor Activity

Eligibility Criteria

65 Years - 85 Years (Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • sedentary elderly
  • individuals who have physical and medical conditions to perform strength training
  • individuals who participate in the Open University Maturity Program

Exclusion Criteria:

  • individuals who do not have physical and medical conditions to perform strength training

Sites / Locations

    Arms of the Study

    Arm 1

    Arm 2

    Arm Type

    Experimental

    No Intervention

    Arm Label

    Group A

    Group B

    Arm Description

    group of elderly participants of strength training program

    group of seniors who did not practice strength training program

    Outcomes

    Primary Outcome Measures

    Change in elderlies's microcirculatory blood flow after 4 months
    The blood flow in the microcirculation in the elderly will be measured by laser-doppler flowmetry. The measures blood flow in the microcirculation will be quantified by the reactive hyperemia Post-occlusion protocol (PORH).
    Change in elderlies's muscle fatigue after 4 months
    muscle fatigue will be quantified by surface electromyography of the muscles of the lower limbs. The electromyographic fatigue threshold and fatigue index will be calculated by the Root Mean Square (RMS) and Median Frequency variables after 4 months.
    Change in elderlies's functional capacity after 4 months
    The functional capacity of the elderly will be evaluated by the Berg Balance Scale, the Timed up-and-go Test, and Falls Efficacy Scale International (FES-I) after 4 months

    Secondary Outcome Measures

    Change in elderlies's strength after 4 months
    The lower body strength of the elderly will be measured by 30-s chair test stand after 4 months.
    Change in elderlies's functional autonomy after 4 months
    The functional autonomy of the elderly will be determined by the general functionality index of the Latin American Development Group to Maturity Protocol after 4 months.

    Full Information

    First Posted
    August 3, 2015
    Last Updated
    August 11, 2016
    Sponsor
    Professor Fernando Figueira Integral Medicine Institute
    Collaborators
    Universidade Estadual da Paraiba
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    1. Study Identification

    Unique Protocol Identification Number
    NCT02516189
    Brief Title
    Strength Training for Elderlies and Their Effects on Muscle Fatigue and Microcirculation - Randomized Clinical Trial
    Official Title
    Strength Training for Elderlies and Their Effects on Muscle Fatigue and Microcirculation - Randomized Clinical Trial
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    August 2016
    Overall Recruitment Status
    Completed
    Study Start Date
    August 2015 (undefined)
    Primary Completion Date
    August 2016 (Actual)
    Study Completion Date
    August 2016 (Actual)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Principal Investigator
    Name of the Sponsor
    Professor Fernando Figueira Integral Medicine Institute
    Collaborators
    Universidade Estadual da Paraiba

    4. Oversight

    Data Monitoring Committee
    No

    5. Study Description

    Brief Summary
    The purpose of this study is to verify the effects of a strength training program on functional capacity, muscle performance and microcirculation in the elderly.
    Detailed Description
    Purpose The primary research question is: Do muscular strength training programs can improve functional capacity, muscle performance and microcirculation in the elderly? Hypothesis: Strength training program will promote electromyographic changes during the development of peripheral muscle fatigue and microcirculatory blood flow contributing to functional autonomy. Secondary Research Questions Does the strength training program in the elderly improve the standard of electromyographic fatigue? Hypothesis: Elderly practitioners of strength exercise program showed increased neuromuscular efficiency and electromyographic fatigue index. Do the strength training program in the elderly improve peripheral microcirculation? Hypothesis: A regular program of strength exercise in the elderly increases the blood flow in peripheral microcirculation changing the process of muscle fatigue. These biomechanical and physiological changes contribute to increased functional autonomy and reducing the risk of falls in the elderly.

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Aging
    Keywords
    Microcirculation, Electromyography, Motor Activity

    7. Study Design

    Primary Purpose
    Basic Science
    Study Phase
    Not Applicable
    Interventional Study Model
    Parallel Assignment
    Masking
    Care Provider
    Allocation
    Randomized
    Enrollment
    80 (Actual)

    8. Arms, Groups, and Interventions

    Arm Title
    Group A
    Arm Type
    Experimental
    Arm Description
    group of elderly participants of strength training program
    Arm Title
    Group B
    Arm Type
    No Intervention
    Arm Description
    group of seniors who did not practice strength training program
    Intervention Type
    Other
    Intervention Name(s)
    Strength training program
    Intervention Description
    Strength Training program applied twice a week for sixteen weeks. Each training exercises has a total time of 50 minutes. Warm-up: 5 minutes of stretching. Training: Leg press; Leg Curl; Vertical traction; Chest press; Abdominal crunch; Lower back. Gametherapy. Relaxation: 5 minutes of stretching.
    Primary Outcome Measure Information:
    Title
    Change in elderlies's microcirculatory blood flow after 4 months
    Description
    The blood flow in the microcirculation in the elderly will be measured by laser-doppler flowmetry. The measures blood flow in the microcirculation will be quantified by the reactive hyperemia Post-occlusion protocol (PORH).
    Time Frame
    4 months
    Title
    Change in elderlies's muscle fatigue after 4 months
    Description
    muscle fatigue will be quantified by surface electromyography of the muscles of the lower limbs. The electromyographic fatigue threshold and fatigue index will be calculated by the Root Mean Square (RMS) and Median Frequency variables after 4 months.
    Time Frame
    4 months
    Title
    Change in elderlies's functional capacity after 4 months
    Description
    The functional capacity of the elderly will be evaluated by the Berg Balance Scale, the Timed up-and-go Test, and Falls Efficacy Scale International (FES-I) after 4 months
    Time Frame
    4 months
    Secondary Outcome Measure Information:
    Title
    Change in elderlies's strength after 4 months
    Description
    The lower body strength of the elderly will be measured by 30-s chair test stand after 4 months.
    Time Frame
    4 months
    Title
    Change in elderlies's functional autonomy after 4 months
    Description
    The functional autonomy of the elderly will be determined by the general functionality index of the Latin American Development Group to Maturity Protocol after 4 months.
    Time Frame
    4 months

    10. Eligibility

    Sex
    All
    Minimum Age & Unit of Time
    65 Years
    Maximum Age & Unit of Time
    85 Years
    Accepts Healthy Volunteers
    Accepts Healthy Volunteers
    Eligibility Criteria
    Inclusion Criteria: sedentary elderly individuals who have physical and medical conditions to perform strength training individuals who participate in the Open University Maturity Program Exclusion Criteria: individuals who do not have physical and medical conditions to perform strength training
    Overall Study Officials:
    First Name & Middle Initial & Last Name & Degree
    Danilo A Vasconcelos, MS
    Organizational Affiliation
    Universidade Estadual da Paraiba
    Official's Role
    Principal Investigator
    First Name & Middle Initial & Last Name & Degree
    João G Alves, PhD
    Organizational Affiliation
    Instituto de Medicina Integral Professor Fernando Figueira
    Official's Role
    Principal Investigator

    12. IPD Sharing Statement

    Learn more about this trial

    Strength Training for Elderlies and Their Effects on Muscle Fatigue and Microcirculation - Randomized Clinical Trial

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