Methylprednisolone Combined Electric-acupuncture on Cognitive Function
Postoperative Complication, Cognitive Retention Disorder
About this trial
This is an interventional prevention trial for Postoperative Complication focused on measuring Elderly, cognitive retention disorder, methylprednisolone
Eligibility Criteria
Inclusion Criteria:
- Aged from 65 to 75
- The American Society of anesthesiologists (American Society of Anesthesiology, ASA) class Ⅱ ~ III
- With a primary culture of above (including elementary school)
- There is no history of drug allergy.
Exclusion Criteria:
- Central nervous system and history of mental illness
- Taking sedatives or antidepressants history
- Insulin dependent diabetes
- Coronary heart disease
- Cerebral infarction
- Preoperative MOCA score less than 26 points
Sites / Locations
- Shengjing hospital of China medical universityRecruiting
Arms of the Study
Arm 1
Arm 2
Placebo Comparator
Experimental
Placebo
Methylprednisolne
Before anesthesia induction, with electroacupuncture can cave, inside the closed cavity, foot three mile point, cupping model for continuous wave type, current pulse frequency of 2 hz, adjust the intensity of the electric acupuncture, with patients complained of needle feeling, can accept no pain and discomfort.Intraoperative sustained electroacupuncture.The same volume of physiological saline will be given.
in the anaesthesia to 1 mg/kg intravenous methylprednisolone, methylprednisolone continuous use 1 mg/kg * d until the third day after surgery.Before anesthesia induction, with electroacupuncture can cave, inside the closed cavity, foot three mile point, cupping model for continuous wave type, current pulse frequency of 2 hz, adjust the intensity of the electric acupuncture, with patients complained of needle feeling, can accept no pain and discomfort.Intraoperative sustained electroacupuncture.