Evaluation of Motor Sparing Knee Block to Infiltration Analgesia for Pain Following Knee Arthroplasty
Osteoarthritis, Knee Arthroplasty, Pain Management
About this trial
This is an interventional treatment trial for Osteoarthritis focused on measuring Adductor canal Block, ultrasound, periarticular injections, Dexmedetomidine
Eligibility Criteria
Inclusion Criteria:
- Male and females of 18-85 years of age, scheduled to undergo elective primary total knee arthroplasty.
- ASA Class I, II, III
- Good contralateral leg strength
Exclusion Criteria:
- ASA physical status 4 or above
- Patients who will need hospitalization due to reason other than the planned surgery.
- Psychiatric illnesses.
- Revision knee surgery
- Narcotic dependency
- Extraneous sources of chronic pain
- Inability to provide informed consent.
- Allergy to any of the drugs used in the study.
- Contraindications to blocks and multimodal analgesia
- Wheel chair bound
Sites / Locations
- University Hospital, London Health Sciences CentreRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Experimental
Experimental
Periarticular
Motor free
Motor free with Dex
Patients in group 1 will receive periarticular infiltration of LA mixture (100 ml) consisting of 0.3% ropivacaine, 2.5 µg/mL of epinephrine, 10 mg of morphine and 30 mg of ketorolac at the end of surgery and sham injections of saline into the motor sparing knee blocks preoperatively.
Patients in group 2 will receive motor sparing knee blocks with 0.5% ropivacaine with 2.5 µg/mL of epinephrine, 30 mg of ketorolac and 10 mg of morphine with a total local anesthetic volume of 60 ml (300 mg). Sham injections of saline (100 ml) will be injected periarticularly at the end of surgery.
Patients in group 3 will receive motor sparing knee blocks with 0.5% ropivacaine with 1 µg/Kg of dexmedetomidine, 30 mg of ketorolac and 10 mg of morphine with a total local anesthetic volume of 60 ml (300 mg). Patients in group 3 will receive sham injections of saline (100 ml) periarticularly at the end of surgery.