Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor
Labor Pain
About this trial
This is an interventional treatment trial for Labor Pain focused on measuring Epidural, Labor analgesia, Programmed intermittent epidural bolus
Eligibility Criteria
Inclusion Criteria:
- ASA I or II
- Full term (≥ 37 weeks gestation)
- nulliparous
- Singleton pregnancy, vertex presentation
- Regular painful contractions occurring at least every 5 minutes
- VAS Pain score at requesting analgesia > 5 (VNPS 0-10)
- Cervical dilatation < 5 cm
Exclusion Criteria:
- Refusal to provide written informed consent.
- Any contraindication to epidural anesthesia
- Accidental dural puncture
- Allergy or hypersensitivity to bupivacaine or fentanyl
- Use of opioids or sedatives within the last 4 hours.
Sites / Locations
- Mount Sinai Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Experimental
Experimental
60 minutes
50 minutes
40 minutes
30 minutes
The infusion pump will deliver programmed intermittent epidural boluses at a 60-minute interval. The bolus will consist of 10mL of 0.0625% Bupivacaine plus fentanyl 2mcg/ml. A PCEA bolus of 5mL of 0.0625% Bupivacaine plus fentanyl 2mcg/ml will also be available.
The infusion pump will deliver programmed intermittent epidural boluses at a 50-minute interval. The bolus will consist of 10mL of 0.0625% Bupivacaine plus fentanyl 2mcg/ml. A PCEA bolus of 5mL of 0.0625% Bupivacaine plus fentanyl 2mcg/ml will also be available.
The infusion pump will deliver programmed intermittent epidural boluses at a 40-minute interval. The bolus will consist of 10mL of 0.0625% Bupivacaine plus fentanyl 2mcg/ml. A PCEA bolus of 5mL of 0.0625% Bupivacaine plus fentanyl 2mcg/ml will also be available.
The infusion pump will deliver programmed intermittent epidural boluses at a 30-minute interval. The bolus will consist of 10mL of 0.0625% Bupivacaine plus fentanyl 2mcg/ml. A PCEA bolus of 5mL of 0.0625% Bupivacaine plus fentanyl 2mcg/ml will also be available.