Patient-Centered Comparative Effectiveness Research (CER) Study of Home-based Interventions to Prevent CA-MRSA Infection Recurrence (CAMP-2)
Methicillin-Resistant Staphylococcus Aureus, Recurrence, Staphylococcal Skin Infections
About this trial
This is an interventional treatment trial for Methicillin-Resistant Staphylococcus Aureus focused on measuring Methicillin-Resistant Staphylococcus aureus, Recurrence, Practice Based Research Network, Community Health Workers/Promotoras, Decolonization and Decontamination, Staphylococcal Skin Infections, Household Transmission
Eligibility Criteria
Inclusion Criteria:
- between 7 to 70 years of age
- fluent in English or Spanish
- plans to receive care in the Community Health Center during the next year
- presents with signs and symptoms of a SSTI
- willing/able to provide informed consent
Exclusion Criteria:
- The patient is unwilling to provide informed consent
- acutely sick (for example, crying, wheezing, bleeding, screaming or shaken)
- unable to participate in a discussion about the study
Sites / Locations
- NYU Lutheran Family Health CentersRecruiting
- NYU Lutheran Medical Center Emergency DepartmentRecruiting
- Coney Island HospitalRecruiting
- Community Healthcare NetworkRecruiting
- Metropolitan Hospital CenterRecruiting
- Urban Health PlanRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Decolonization and Decontamination
Usual Care
Index Patients will receive: 1) guidelines-directed care, which may consist of incision, drainage, oral antibiotics, and antibiogram-based antibiotic prescribing, and 2) a home-based intervention implemented by Community Health Workers/Promotoras that includes index patient and household member education and instructions to complete a decolonization and decontamination regimen, along with printed materials describing a standard hygiene protocol for reducing household contamination. Index patients and consenting household members will complete a decolonization regimen consisting of twice-daily application of 2% mupirocin ointment to the anterior nares with a clean cotton applicator for five days, as well as daily bathing with chlorhexidine wash for five days. The household decontamination hygiene protocol includes the use of hand-washing, surface disinfection, and laundering.
Index Patients will receive: 1) guidelines-directed care, which may consist of incision, drainage, and oral antibiotics, as well as antibiogram-based antibiotic prescribing, and 2) printed materials describing a standard hygiene protocol for reducing household contamination.