Cognitive Training for the Remediation of Functional Brain Health in HIV
HIV - Human Immunodeficiency Virus, Cognitive Impairment
About this trial
This is an interventional diagnostic trial for HIV - Human Immunodeficiency Virus focused on measuring HIV - Human Immunodeficiency Virus, Memory, Concentration
Eligibility Criteria
Inclusion Criteria:
- age 35 years or older;
- HIV infection for at least 1 year;
- able to communicate in English or French;
- capable of providing informed consent;
- easy access to the internet;
- EEG and MRI compatible
Exclusion Criteria:
- presence of dementia;
- life expectancy < 3 y;
- other neurological disorder including active opportunistic CNS infection;
- psychotic disorder;
- current substance dependence or abuse; and
- Hepatitis C requiring interferon therapy during the study period
Sites / Locations
- Montreal Neurological Institute and Hospital (McGill University)
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Immediate cognitive training group
Waitlist control group
Plasticity-based Adaptive Cognitive Remediation (PACR) is an 8 week training to improve executive functions (e.g., working memory, flexibility, cognitive control) as well as attention. Participants in the immediate cognitive training group will receive the PACR intervention shortly after enrollment.
Participants in the waitlist control group will receive a brochure with 8 simple tips for better brain health around the time of enrollment. They will begin the Plasticity-based Adaptive Cognitive Remediation (PACR) intervention within 8 weeks of the initial enrollment.