Peri-Implantitis Surgical Treatment an RCT Study
Peri-implantitis
About this trial
This is an interventional treatment trial for Peri-implantitis focused on measuring Peri-implantitis, Peri-implant disease, Dental implants, Guided bone regeneration
Eligibility Criteria
Inclusion Criteria:
- It will include individuals diagnosed with early to moderate peri-implantitis (probing depth between 5 and 10 mm) rehabilitated with implant supporting fixed prosthesis for at least 6 months. Due to the great variation in implants' length the probing depth can shows great variability. In this way it is complicated to establish a cutoff point to define the severity of the disease. So in order to minimize this limitation, the peri-implant bone defect should be angular or circular involving at least 3 threads and should not exceed 50% of the total length of the implant.
Exclusion Criteria:
- Smokers
- Individuals with blood glucose more than 120 mg/dl or Insulin dependent diabetes
- Individuals who have undergone treatment of peri-implant disease over the last 6 months
- Individuals who used antibiotic therapy, for any reason, in the last 3 months
- Individuals who have any systemic condition that prevents surgical treatment
- Refusal to sign the informed consent
- A history of local radiotherapy to the head and neck region
- Pregnancy and lactation
- Active, uncontrolled periodontal pathology of the remaining dentition
Sites / Locations
- Federal University of Minas Gerais
Arms of the Study
Arm 1
Arm 2
Experimental
Other
JHS COL-HAP91 + JHS HAP-91
surgical and mechanical debridement
Surgical flaps debridement with plastic curette Implacare Hu-Friedy, cleaning the surface with chlorhexidine gel 2% 3 minutes and irrigation with saline solution 0.9 %. Bone defects will be treated with JHS COL-HAP91 (porous hydroxyapatite + collagen) + JHS HAP-91 (porous hydroxyapatite). Amoxicillin 500 mg 3 times/day 7 days, Tylenol 750 mg 3 times/day, and Nimesulide 100 mg 2 times/day will be prescribed.
Surgical flaps: All groups will receive the same surgical treatment for implant surface decontamination. Surgical intervention will be performed with full thickness mucoperiosteal flaps. Debridement with plastic curette Implacare Hu-Friedy, cleaning the surface with chlorhexidine gel 2% 3 minutes and irrigation with saline solution 0.9 %. Amoxicillin 500 mg 3 times/day 7 days, Tylenol 750 mg 3 times/day and Nimesulide 100 mg 2 times/day will be prescribed.