Multisensorial Information's Treatment in Autism Spectrum Disorder
Primary Purpose
Autism
Status
Completed
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
memory test
Sponsored by
About this trial
This is an interventional basic science trial for Autism
Eligibility Criteria
Inclusion Criteria:
- Boy or girl,
- 7 - 13 years,
- Presenting a diagnosis DSM IV of disorder(confusion) of the autistic spectre: detected by the scale(ladder) ADI ( Autism Diagnostic Interview) or by TEENAGERS (Autism Diagnostic Observation Schedule): typical autistic. These patients do not answer the diagnosis of psychosis according to Kiddie-SADS,
- Upper total IQ or equal to 50, examination dating less than year before the inclusion,
- French-speaking children,
- Signature of the informed consent by the parents(relatives) and the child,
- Membership to the Social Security.
Exclusion Criteria:
- Genetic, neurological or neurosensory pathologies,
- Diagnosis of intrusive disorder(confusion) of the not specified development: TED our,
- The patients will not be included who would participate in a program or a study of reeducation in the social fitnesses.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm Type
Other
Other
Arm Label
autistic patient
healthy volunteers
Arm Description
patient with autistic trouble
healthy volunteers
Outcomes
Primary Outcome Measures
rate of reminder after 30 minutes between the group autistic and the group witness( %)
Comparison between the group autistic and the group witness of the difference enter the rate of reminder(abseiling) in 30 minutes of the words proposed in video and audio sequences.
Secondary Outcome Measures
Difference of the scores of reminders words (%)
Difference of the scores of reminders between the both group, immediately after procedure and 30 minutes after procedure
Full Information
NCT ID
NCT02579109
First Posted
September 29, 2015
Last Updated
October 16, 2015
Sponsor
Centre Hospitalier Universitaire de Nice
1. Study Identification
Unique Protocol Identification Number
NCT02579109
Brief Title
Multisensorial Information's Treatment in Autism Spectrum Disorder
Official Title
Exploring Social Cognition in Autism Spectrum Disorder With Long Time Memory Task. Controlled Study on 8-13 Years Childs
Study Type
Interventional
2. Study Status
Record Verification Date
October 2015
Overall Recruitment Status
Completed
Study Start Date
February 2014 (undefined)
Primary Completion Date
February 2014 (Actual)
Study Completion Date
August 2014 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Centre Hospitalier Universitaire de Nice
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Introduction:
Autism spectrum disorder is characterized by deficits in three functional domains: language and communication, social reciprocity, and the presence of restricted interests/repetitive behaviors. There's also deficits in social cognition. When having a face-to-face conversation, a listener not only hears what a speaker is saying, but also sees the articulatory gestures that accompany those sounds. Speech signals needs then a multisensory processing. Impairments in multisensory perceptual binding may be particularly relevant in ASD, given that hallmark features of the disorder include difficulties in speech, communication, and social interactions.
Objectives:
The investigator suggest that atypical multisensory processing in ASD may have an impact on speech perception and social processing.
Aims:
Methods:
This pilot study measures free recall scores in 3 lists of words presentation after 30 minutes. In the first condition (CI) words are only listening. In the second condition (CII) words are associated with a picture of a mans face. In the third condition (CIII) words are associated with a video of a man speaking. Three lists are homogeneous form words characteristics (lexical frequency, emotional valence norm, imageability). Participants were 7- to 13-year-olds typically developing children (TD) (N = 19) and ASD children (N = 19).
The investigator would create some new tools for exploring the treatment of a social information. These tools should be the closest of a ecological social interaction.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Autism
7. Study Design
Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
38 (Actual)
8. Arms, Groups, and Interventions
Arm Title
autistic patient
Arm Type
Other
Arm Description
patient with autistic trouble
Arm Title
healthy volunteers
Arm Type
Other
Arm Description
healthy volunteers
Intervention Type
Other
Intervention Name(s)
memory test
Primary Outcome Measure Information:
Title
rate of reminder after 30 minutes between the group autistic and the group witness( %)
Description
Comparison between the group autistic and the group witness of the difference enter the rate of reminder(abseiling) in 30 minutes of the words proposed in video and audio sequences.
Time Frame
30 minutes
Secondary Outcome Measure Information:
Title
Difference of the scores of reminders words (%)
Description
Difference of the scores of reminders between the both group, immediately after procedure and 30 minutes after procedure
Time Frame
30 minutes
10. Eligibility
Sex
All
Minimum Age & Unit of Time
7 Years
Maximum Age & Unit of Time
13 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Boy or girl,
7 - 13 years,
Presenting a diagnosis DSM IV of disorder(confusion) of the autistic spectre: detected by the scale(ladder) ADI ( Autism Diagnostic Interview) or by TEENAGERS (Autism Diagnostic Observation Schedule): typical autistic. These patients do not answer the diagnosis of psychosis according to Kiddie-SADS,
Upper total IQ or equal to 50, examination dating less than year before the inclusion,
French-speaking children,
Signature of the informed consent by the parents(relatives) and the child,
Membership to the Social Security.
Exclusion Criteria:
Genetic, neurological or neurosensory pathologies,
Diagnosis of intrusive disorder(confusion) of the not specified development: TED our,
The patients will not be included who would participate in a program or a study of reeducation in the social fitnesses.
12. IPD Sharing Statement
Learn more about this trial
Multisensorial Information's Treatment in Autism Spectrum Disorder
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