Total/Subtotal Colectomy in Ovarian Cancer
Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
About this trial
This is an interventional treatment trial for Epithelial Ovarian Cancer focused on measuring Total or subtotal colectomy, Ovarian cancer, Complications, One-year disease-free survival, Stage IIIc, Stage IV
Eligibility Criteria
Inclusion Criteria:
- Age ≥18 years and ≤ 75 years.
- Epithelial ovarian cancer, fallopian tube cancer, primary peritoneal carcinoma with pathology confirmed International Federation of Gynecology and Obstetrics (FIGO) stage IIIc or IV
- Extensive colonic metastasis, tumor involving the major part of bowel surface and/or mesentery
- Optimal cytoreductive surgery, including hysterectomy, bilateral salpinges-oophorectomy, omentectomy, and resection of all metastatic lesions, with a residual disease no more than 0.5cm
- Eastern Cooperative Oncology Group (ECOG) performance status 0-2.
- American Society of Anesthesiologists (ASA) performance 1-2.
- Follow-up available.
- Written informed consent.
Exclusion Criteria:
- Low-malignant potential ovarian tumor.
- Patient who underwent enterostomy in the surgery procedure.
- Tumor involving small intestine alone.
- More than 2 anastomoses.
- Other condition that could interfere with provision of informed consent, compliance to study procedures, or follow-up.
- Prior invasive malignancies within the last 5 years showing activity of disease.
Sites / Locations
- Fudan University Shanghai Zhongshan HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Total or Subtotal Colectomy
Other Bowel Resection
all patients who underwent total colectomy(removal of the large intestine from ileum to the rectum. After it is removed, the end of the small intestine is sewn to the rectum) or subtotal colectomy(removal of transverse colon, descending colon, sigmoid colon to the rectum. After it is removed, the end of the ascending colon is sewn to the rectum)as part of optimal cytoreductive surgery
all patients who underwent partial intestinal resection as part of optimal cytoreductive surgery