Skin and Soft Tissue Infection (SSTI) Study
Skin Diseases, Infectious, Soft Tissue Infections
About this trial
This is an interventional treatment trial for Skin Diseases, Infectious focused on measuring Abscess, Antiseptic, Provodine, Povidone-Iodine
Eligibility Criteria
Inclusion Criteria:
- Skin abscess
- Treatment requiring incision and drainage
Exclusion Criteria:
- Unable or unwilling to provide informed consent
- Homeless, incarcerated, or living in a group home
- Abscess on the face or breast
- Abscess requiring surgical drainage in the operating room or requiring admission to the hospital
- Intravenous drug users
- Previous enrollment in this study
- Documented history of iodine sensitivity
Sites / Locations
- University Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Provodine
Standard Care
Provodine patients will have standard care including incision and drainage. The contents of 1 packet of Provodine applied with a Q-tip to the walls and floor of the abscess cavity. The contents of a 2nd packet will be applied to the surrounding skin within 5 cm around the incision. Provodine patients will return within 48-72 hours for a follow-up visit, have the packing removed and the contents of the packet reapplied to the abscess cavity and surrounding skin. Provodine patients will be instructed to cleanse the abscess at home by soaking in water once a day and patting the wound dry. They will wash their hands with soap and water, pat dry, and apply the contents of 1 packet of Provodine to dorsum and palmar aspects of hands and fingers and rub together for 1 minute. They will apply the contents of a 2nd packet to the abscess cavity, and a 3rd packet to the surrounding skin. They will be then rinse their hands with water, pat dry, and cover the wound with 4x4 gauze.
Standard care patients will have standard care including incision and drainage. Standard care patients will return within 48-72 hours for a follow-up visit and have the packing removed. Standard care patients will be instructed to cleanse the abscess at home by soaking in water once a day and patting the wound dry. They will cover wound with 4x4 gauze and wash hands with soap and water for 1 minute.