Aerobic Exercise for Cognition in Schizophrenia
Schizophrenia
About this trial
This is an interventional treatment trial for Schizophrenia focused on measuring Schizophrenia, Exercise, Cognition
Eligibility Criteria
Inclusion Criteria:
- Diagnosis of schizophrenia or schizoaffective disorder
- maintained on stable doses of outpatient psychiatric medications for at least 30 days
- compliant with outpatient follow-up
- have a stable place to live
- access to transportation to the hospital
- doing less than 20 minutes per week of regular physical activity in the past month
Exclusion Criteria:
- Bipolar disorder;
- active substance dependence within the prior 30 days
- more than 2 psychiatric admissions within the prior six months
- known HIV infection or AIDS
- history of traumatic brain injury
- current seizure disorder
- Alzheimer's disease or other dementia
- clinical history of mild cognitive impairment
- Parkinson's disease
- other current clinically significant neurological disease
- unstable medical condition that would be expected to interfere with fitness training
- significant hearing or visual impairment
Sites / Locations
- Atlanta VA Medical and Rehab Center, Decatur, GA
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Aerobic Exercise
Balance and Stretching
Subjects with a diagnosis of SCZ will complete aerobic exercises consisting of spin classes 3 times a week on a stationary bicycle ergometer. Exercise time will progress from an initial 20 minutes per session to a maximum of 45 minutes by increasing 5 minutes each week for 12 weeks.
Subjects with a diagnosis of SCZ will complete a balance and stretching program consisting of progressive whole body stretching and toning exercises. Exercise time will progress from an initial 20 minutes per session to a maximum of 45 minutes by increasing 5 minutes each week for 12 weeks.